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产品概述
名称 | SK-OV-3 (人卵巢癌细胞) (STR鉴定正确) |
别称 | SKOV-3; SK.OV.3; SKOV3; Skov3; SKO3 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | SK-OV-3细胞是由G·Trempe和L·J·Old于1973年从卵巢肿瘤病人的腹水分离得到。SK-OV-3细胞对肿瘤坏死因子和几种细胞毒性药物包括白喉毒素、顺铂和阿霉素均耐受。SK-OV-3细胞在裸鼠中致瘤,且形成与卵巢原位癌一致的中度分化的腺癌。 |
年龄(性别) | 女性;64岁 |
组织来源 | 卵巢腺癌,腹水转移 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 卵巢癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~20-48 hours |
致瘤性 | Yes, in nude mice; forms moderately well differentiated adenocarcinoma consistent with ovarian primary. |
抗原表达情况 | Blood Type B; Rh+ |
基因表达情况 | Blood Type B; Rh+ |
保藏机构 | ATCC; HTB-77 ECACC; 91091004 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11 D2S1338 18,23 D3S1358 14 D5S818 11 D7S820 13 D8S1179 14,15 D13S317 8,11 D16S539 12 D18S51 16,17,18 D19S433 14,14.2 D21S11 30,31.2 FGA 24,25 PentaD 12,13 PentaE 5,13 TH01 9,9.3 TPOX 7,8,11 vWA 17,18 D6S1043 12 D12S391 22 D2S441 10,11.3 -
STR鉴定图
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参考文献
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Combined inhibition of HER2 and VEGFR synergistically improves therapeutic efficacy via PI3K-AKT pathway in advanced ovarian cancer (2024-02-26)
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-024-02981-5
影响因子 :11.3
引用产品: NIH:OVCAR-3 [OVCAR3] 细胞 , SK-OV-3 细胞 , McCoy's 5A 培养基
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ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis (2024-02-21)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-024-04980-8
影响因子 :7.4
引用产品: OVCAR-8 细胞 , SK-OV-3 细胞 , ES-2 细胞
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m6A methylation-mediated regulation of LncRNA MEG3 suppresses ovarian cancer progression through miR-885-5p and the VASH1 pathway (2024-01-29)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-024-04929-x
影响因子 :7.4
引用产品: A2780 细胞 , Caov-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , SK-OV-3 细胞 , IOSE80 细胞
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Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors (2024-02-27)
期刊:JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1021/acs.jmedchem.3c02039
影响因子 :7.3
引用产品: SK-OV-3 细胞 , HCT-15 细胞 , CHO 细胞
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An exosome-derived lncRNA signature identified by machine learning associated with prognosis and biomarkers for immunotherapy in ovarian cancer (2024-02-09)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2024.1228235
影响因子 :7.3
引用产品: SK-OV-3 细胞 , IOSE80 细胞 , OVCAR-8 细胞
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Portulaca oleracea L. polysaccharide inhibits ovarian cancer via inducing ACSL4-dependent ferroptosis (2024-03-19)
期刊:Aging-US
影响因子 :5.2
引用产品: SK-OV-3 细胞 , Hey 细胞
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Signatures of tumor-associated macrophages correlate with treatment response in ovarian cancer patients (2024-01-03)
期刊:Aging-US
影响因子 :5.2
引用产品: A2780 细胞 , SK-OV-3 细胞 , RPMI-1640 培养基
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The roles of autophagy, ferroptosis and pyroptosis in the anti-ovarian cancer mechanism of harmine and their crosstalk (2024-03-18)
期刊:Scientific Reports
DOI:10.1038/s41598-024-57196-7
影响因子 :4.6
引用产品: IOSE80 细胞 , SK-OV-3 细胞 , ES-2 细胞 , A2780 细胞
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KIF26B and CREB3L1 Derived from Immunoscore Could Inhibit the Progression of Ovarian Cancer (2024-02-13)
期刊:Journal of Immunology Research
影响因子 :4.1
引用产品: SK-OV-3 细胞
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Design, synthesis and biological evaluation of rhein–piperazine–furanone hybrids as potential anticancer agents (2024-02-13)
期刊:RSC Medicinal Chemistry
影响因子 :4.1
引用产品: A549 [A-549] 细胞 , NCI-H460 [H460] 细胞 , PC-9 细胞 , Calu-1 细胞 , SK-BR-3 [SKBR3] 细胞 , SK-OV-3 细胞 , 786-O [786-0] 细胞 , HuH-7 细胞 , HCT 116 细胞 , Hela 细胞 , WI-38 细胞 , MCF 10A 细胞 , KGN 细胞 , 293T [HEK-293T] 细胞 , DMEM高糖 培养基 , MEM 培养基 , DMEM/F12 培养基 , McCoy's 5A 培养基 , RPMI-1640 培养基 , 0.25%胰蛋白酶溶液 (含EDTA,溶于PBS)
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CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells (2024-03-27)
期刊:Journal of Ovarian Research
DOI:10.1186/s13048-024-01393-5
影响因子 :4.0
引用产品: Annexin V Binding Buffer (1×) , SK-OV-3 细胞 , Hey 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , A2780 细胞 , ES-2 细胞 , HO-8910 细胞 , IOSE-80 细胞
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MAPRE3 as an epigenetic target of EZH2 restricts ovarian cancer proliferation in vitro and in vivo (2024-01-08)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2024.113913
影响因子 :3.7
引用产品: Anglne 细胞 , SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞
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Lipopolysaccharide-Educated Cancer-Associated Fibroblasts Facilitate Malignant Progression of Ovarian Cancer Cells via the NF-kB/IL-6/JAK2 Signal Transduction (2024-02-02)
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-024-01055-3
影响因子 :2.6
引用产品: SK-OV-3 细胞 , HEY A8 细胞
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A morpholine derivative N-(4-morpholinomethylene)ethanesulfonamide induces ferroptosis in tumor cells by targeting NRF2 (2024-01-30)
期刊:BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子 :2.0
引用产品: 22RV1 细胞 , LNCaP clone FGC 细胞 , C4-2 细胞 , SK-OV-3 细胞
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Honokiol induces ferroptosis in ovarian cancer cells through the regulation of YAP by OTUB2 (2024-03-13)
期刊:JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
影响因子 :1.6
引用产品: SK-OV-3 细胞
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Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression (2023-10-12)
期刊:CELL DEATH AND DIFFERENTIATION
DOI:10.1038/s41418-023-01226-w
影响因子 :12.4
引用产品: 293T [HEK-293T] 细胞 , SK-OV-3 细胞 , Caov-3 细胞 , A2780 细胞 , Hey 细胞 , SW626 细胞 , Anglne 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞
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Rational Design of Esterase-Insensitive Fluorogenic Probes for In Vivo Imaging (2023-05-05)
期刊:ACS Sensors
DOI:10.1021/acssensors.3c00264
影响因子 :8.9
引用产品: SK-OV-3 细胞 , KB 细胞
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Diterpenoid honatisine overcomes temozolomide resistance in glioblastoma by inducing mitonuclear protein imbalance through disruption of TFAM-mediated mtDNA transcription (2023-12-29)
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2023.155328
影响因子 :7.9
引用产品: SK-OV-3 细胞 , Caco-2 细胞 , PANC-1 细胞 , PC-3 细胞 , NCI-H1395 细胞 , MCF7 [MCF-7] 细胞
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A novel estrogen-targeted PEGylated liposome co-delivery oxaliplatin and paclitaxel for the treatment of ovarian cancer (2023-01-30)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2023.114304
影响因子 :7.5
引用产品: SK-OV-3 细胞
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The application of HER2 and CD47 CAR-macrophage in ovarian cancer (2023-09-22)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04479-8
影响因子 :7.4
引用产品: SK-OV-3 细胞 , A2780 细胞 , THP-1 细胞
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Identification of prognostic and diagnostic signatures for cancer and acute myocardial infarction: multi-omics approaches for deciphering heterogeneity to enhance patient management (2023-09-14)
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2023.1249145
影响因子 :5.6
引用产品: 人卵巢上皮细胞 , SK-OV-3 细胞
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Therapeutic potential of miRNAs in placental extracellular vesicles in ovarian and endometrial cancer (2023-10-06)
期刊:Human Cell
DOI:10.1007/s13577-023-00986-4
影响因子 :4.3
引用产品: SK-OV-3 细胞 , Ishikawa 细胞
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The role of OIP5 in the carcinogenesis and progression of ovarian cancer (2023-09-02)
期刊:Journal of Ovarian Research
DOI:10.1186/s13048-023-01265-4
影响因子 :4.0
引用产品: SK-OV-3 细胞 , A2780 细胞 , 人卵巢上皮细胞
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Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM) (2023-04-22)
期刊:Journal of Ovarian Research
DOI:10.1186/s13048-023-01156-8
影响因子 :4.0
引用产品: SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , ES-2 细胞 , A2780 细胞
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N6-methyladenosine methylation regulator FTO promotes oxidative stress and induces cell apoptosis in ovarian cancer (2023-02-22)
期刊:Epigenomics
影响因子 :3.8
引用产品: SK-OV-3 细胞
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Revealing the inhibitory effect of VASH1 on ovarian cancer from multiple perspectives (2023-11-27)
期刊:CANCER BIOLOGY & THERAPY
DOI:10.1080/15384047.2023.2285817
影响因子 :3.6
引用产品: A2780 细胞 , Caov-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , SK-OV-3 细胞 , IOSE80 细胞
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Ovarian carcinoma immune-related microRNA affects the heterogeneity of the endocrine microenvironment and anti-tumor immune pattern (2023-10-09)
期刊:JOURNAL OF GENE MEDICINE
DOI:10.1002/jgm.3602
影响因子 :3.5
引用产品: SK-OV-3 细胞 , A2780 细胞
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ARID5B promoted the histone demethylation of SORBS2 and hampered the metastasis of ovarian cancer (2023-11-03)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.8
引用产品: A2780 细胞 , SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞
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LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA3 (2023-02-01)
期刊:Recent Patents on Anti-Cancer Drug Discovery
DOI:10.2174/1574892817666220316152201
影响因子 :2.8
引用产品: SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , A2780 细胞 , HO-8910 细胞 , 人卵巢上皮细胞
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Comparative proteomic analysis of the mitochondria of menstrual stem cells and ovarian cancer cells (2023-01-16)
期刊:Experimental and Therapeutic Medicine
影响因子 :2.7
引用产品: SK-OV-3 细胞
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Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription (2002-02-20)
期刊:Journal Of Experimental & Clinical Cancer Research
DOI:10.1186/s13046-022-02260-1
影响因子 :11.3
引用产品: Hs 578T 细胞 , BT-549 细胞 , HCT-15 细胞 , MCF 10A 细胞 , A549 [A-549] 细胞 , SK-OV-3 细胞 , Hela 细胞 , PANC-1 细胞
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Toosendanin reduces cisplatin resistance in ovarian cancer through modulating the miR-195/ERK/β-catenin pathway (2022-11-25)
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2022.154571
影响因子 :6.7
引用产品: Annexin V-FITC/ PI荧光双染细胞凋亡检测试剂盒 , Annexin V-APC/ PI荧光双染细胞凋亡检测试剂盒 , SK-OV-3 细胞
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Wenshenyang recipe treats infertility through hormonal regulation and inflammatory responses revealed by transcriptome analysis and network pharmacology (2022-08-08)
期刊:Frontiers in Pharmacology
影响因子 :6.0
引用产品: SK-OV-3 细胞
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Circular RNA lysophosphatidic acid receptor 3 (circ-LPAR3) enhances the cisplatin resistance of ovarian cancer (2001-02-20)
期刊:Bioengineered
DOI:10.1080/21655979.2022.2029109
影响因子 :4.9
引用产品: A2780 细胞 , SK-OV-3/DDP 细胞 , A2780/DDP 细胞 , SK-OV-3 细胞 , SK-OV-3细胞专用培养基 , SK-OV-3/DDP细胞专用培养基 , A2780细胞专用培养基 , A2780/DDP细胞专用培养基 , NCI-H1299 细胞 , A549 [A-549] 细胞 , HCC827 细胞 , NCI-H460 [H460] 细胞
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Knockdown of lncRNA ACTA2-AS1 reverses cisplatin resistance of ovarian cancer cells via inhibition of miR-378a-3p-regulated Wnt5a (2004-02-20)
期刊:Bioengineered
DOI:10.1080/21655979.2022.2061181
影响因子 :4.9
引用产品: A2780 细胞 , SK-OV-3 细胞
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Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway (2022-11-04)
期刊:JOURNAL OF PHARMACY AND PHARMACOLOGY
影响因子 :4.8
引用产品: SK-OV-3 细胞
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LPA3 is a precise therapeutic target and potential biomarker for ovarian cancer (2001-02-20)
期刊:Medical Oncology
DOI:10.1007/s12032-021-01616-5
影响因子 :3.4
引用产品: A2780 细胞 , SK-OV-3 细胞
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Norcantharidin induces ferroptosis via the suppression of NRF2/HO‑1 signaling in ovarian cancer cells (2022-08-25)
期刊:Oncology Letters
影响因子 :3.1
引用产品: SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞
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Circ_0021573 acts as a competing endogenous RNA to promote the malignant phenotypes of human ovarian cancer cells (2022-12-05)
期刊:Reproductive Biology
DOI:10.1016/j.repbio.2022.100704
影响因子 :2.1
引用产品: SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , A2780 细胞 , ES-2 细胞 , 293T [HEK-293T] 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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A smart O2-generating nanocarrier optimizes drug transportation comprehensively for chemotherapy improving (2003-01-20)
期刊:Acta Pharmaceutica Sinica B
DOI:10.1016/j.apsb.2021.04.021
影响因子 :14.5
引用产品: SK-OV-3 细胞
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A solid lipid coated calcium peroxide nanocarrier enables combined cancer chemo/chemodynamic therapy with O2/H2O2 self-sufficiency (2001-01-20)
期刊:Acta Biomaterialia
DOI:10.1016/j.actbio.2020.12.036
影响因子 :9.3
引用产品: SK-OV-3 细胞
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Combination of Chemotherapy and Photodynamic Therapy with Oxygen Self-Supply in the Form of Mutual Assistance for Cancer Therapy (2005-01-20)
期刊:International Journal of Nanomedicine
影响因子 :8.0
引用产品: SK-OV-3 细胞
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Isothiocyanate Iberin inhibits cell proliferation and induces cell apoptosis in the progression of ovarian cancer by mediating ROS accumulation and GPX1 expression (2006-01-20)
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.111533
影响因子 :7.5
引用产品: CoC1 细胞 , SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , RPMI-1640 培养基 , McCoy's 5A 培养基
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Oncogenic microRNA-181d binding to OGT contributes to resistance of ovarian cancer cells to cisplatin (2012-01-20)
期刊:Cell Death Discovery
DOI:10.1038/s41420-021-00715-6
影响因子 :7.0
引用产品: CoC1 细胞 , CoC1/DDP 细胞 , SK-OV-3 细胞
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Co-encapsulation of (−)-epigallocatechin-3-gallate and piceatannol/oxyresveratrol in β-lactoglobulin: effect of ligand–protein binding on the antioxidant activity, stability, solubility and cytotoxicity (2006-01-20)
期刊:Food & Function
影响因子 :6.3
引用产品: SK-OV-3 细胞
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The anticancer effect of extract of medicinal mushroom Sanghuangprous vaninii against human cervical cancer cell via endoplasmic reticulum stress-mitochondrial apoptotic pathway (2006-01-20)
期刊:Journal Of Ethnopharmacology
影响因子 :5.4
引用产品: SGC-7901 细胞 , SiHa 细胞 , SK-OV-3 细胞
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P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway (2008-01-20)
期刊:Cell Cycle
DOI:10.1080/15384101.2021.1963910
影响因子 :5.2
引用产品: OV-90 细胞 , A2780 细胞 , SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , 人卵巢上皮细胞 , NIH:OVCAR-3 [OVCAR3]细胞专用培养基 , 人卵巢上皮细胞完全培养基 , OV-90细胞专用培养基
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MiR-29c downregulates tumor-expressed B7-H3 to mediate the antitumor NK-cell functions in ovarian cancer (2004-01-20)
期刊:Gynecologic Oncology
DOI:10.1016/j.ygyno.2021.04.013
影响因子 :4.7
引用产品: A2780 细胞 , 人卵巢上皮细胞 , SK-OV-3 细胞 , ES-2 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞
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CircLNPEP promotes the progression of ovarian cancer through regulating miR-876-3p/ WNT5A axis (2008-01-20)
期刊:Cell Cycle
DOI:10.1080/15384101.2021.1965723
影响因子 :4.3
引用产品: A2780 细胞 , SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , SK-BR-3 [SKBR3] 细胞
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Curcumin inhibits ovarian cancer progression by regulating circ-PLEKHM3/miR-320a/SMG1 axis (2011-01-20)
期刊:Journal of Ovarian Research
DOI:10.1186/s13048-021-00916-8
影响因子 :4.0
引用产品: A2780 细胞 , SK-OV-3 细胞 , 293T [HEK-293T] 细胞
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CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3 (2011-01-20)
期刊:Journal of Ovarian Research
DOI:10.1186/s13048-021-00875-0
影响因子 :4.0
引用产品: A2780 细胞 , SK-OV-3 细胞 , 人卵巢上皮细胞 , 293T [HEK-293T] 细胞
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RNA-binding protein IGF2BP2 enhances circ_0000745 abundancy and promotes aggressiveness and stemness of ovarian cancer cells via the microRNA-3187-3p/ERBB4/PI3K/AKT axis (2011-01-20)
期刊:Journal of Ovarian Research
DOI:10.1186/s13048-021-00917-7
影响因子 :4.0
引用产品: CoC1 细胞 , SW626 细胞 , ES-2 细胞 , SK-OV-3 细胞
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Long non-coding RNA SNHG25 promotes epithelial ovarian cancer progression by up-regulating COMP (2001-01-20)
期刊:Journal of Cancer
影响因子 :3.9
引用产品: A2780 细胞 , SK-OV-3 细胞 , Hey 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞
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Screening of CXC chemokines in the microenvironment of ovarian cancer and the biological function of CXCL10 (2011-01-20)
期刊:World Journal of Surgical Oncology
DOI:10.1186/s12957-021-02440-x
影响因子 :3.2
引用产品: VE 细胞 , SK-OV-3 细胞
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An Activity-Based Fluorogenic Probe Enables Cellular and in Vivo Profiling of Carboxylesterase Isozymes (2007-00-20)
期刊:Analytical Chemistry
DOI:10.1021/acs.analchem.0c01554
影响因子 :7.4
引用产品: Hep G2 细胞 , SK-OV-3 细胞 , Hela 细胞
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Knockdown of long non-coding RNA HOTAIR reverses cisplatin resistance of ovarian cancer cells through inhibiting miR-138-5p-regulated EZH2 and SIRT1 (2004-00-20)
期刊:Biological Research
DOI:10.1186/s40659-020-00286-3
影响因子 :6.7
引用产品: A2780 细胞 , SK-OV-3 细胞
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miR‑576‑3p overexpression enhances cisplatin sensitivity of ovarian cancer cells by dysregulating PD‑L1 and cyclin D1 (2011-00-20)
期刊:Molecular Medicine Reports
影响因子 :3.4
引用产品: SK-OV-3 细胞
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MiR-337–3p suppresses proliferation of epithelial ovarian cancer bytargeting PIK3CA and PIK3CB (2010-09-20)
期刊:Cancer Letters
DOI:10.1016/j.canlet.2019.10.021
影响因子 :9.7
引用产品: A2780 细胞 , 293T [HEK-293T] 细胞 , SK-OV-3 细胞 , NIH:OVCAR-3 [OVCAR3] 细胞 , ES-2 细胞
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IR780-loaded folate-targeted nanoparticles for near-infrared fluorescence image-guided surgery and photothermal therapy in ovarian cancer (2004-09-20)
期刊:International Journal of Nanomedicine
影响因子 :8.0
引用产品: SK-OV-3 细胞
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The Antitumor Potential of Extract of the Oak Bracket Medicinal Mushroom Inonotus baumii in SMMC-7721 Tumor Cells (2009-09-20)
期刊:Evidence-based Complementary and Alternative Medicine
影响因子 :2.7
引用产品: SMMC-7721 细胞 , A-375 细胞 , U-87 MG 细胞 , MDA-MB-231 细胞 , SK-OV-3 细胞
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Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization (2005-07-20)
期刊:Oncogene
影响因子 :8.0
引用产品: A2780 细胞 , SK-OV-3 细胞 , ES-2 细胞 , MCF7 [MCF-7] 细胞
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