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产品概述
| 名称 | MFC (小鼠胃癌细胞) (STR鉴定正确) |
| 别称 | Mouse Forestomach Carcinoma |
| 种属 | 小鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | MFC细胞是由钱书森、高进等于1985年建立；利用源自615小鼠前胃鳞癌移植瘤FC瘤组织，小块法培养得到，已传132代；MFC细胞细胞在615小鼠皮下移植100%成功。 |
| 年龄（性别） | 不详 |
| 组织来源 | 胃癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胃癌细胞 |
STR鉴定
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STR位点信息
18-3 17,18 6-7 15 5-5 12 X-1 27 1-2 15,16,17 7-1 30 8-1 16 1-1 10,15 19-2 12 15-3 21.3 12-1 16,17 6-4 15.3 4-2 20.3 3-2 13,14 2-1 16 13-1 17.1
11-2 13,14,18 17-2 15 -
STR鉴定图
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参考文献
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KDM3A Ablation Activates Endogenous Retrovirus Expression to Stimulate Antitumor Immunity in Gastric Cancer (2024-07-19)
期刊：Advanced Science
影响因子 ：14.3
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Overall survival prediction of gastric cancer using the gene signature of CT-detected extramural venous invasion combined with M2 macrophages infiltration (2024-09-09)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05628-3
影响因子 ：6.1
引用产品： GES-1 细胞 , AGS 细胞 , HGC-27 细胞 , KATO III [KATO 3] 细胞 , MKN1 细胞 , MKN-45 细胞 , MFC 细胞
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RORα inhibits gastric cancer proliferation through attenuating G6PD and PFKFB3 induced glycolytic activity (2024-01-06)
期刊：Cancer Cell International
DOI：10.1186/s12935-023-03201-4
影响因子 ：5.8
引用产品： AGS 细胞 , MKN74 细胞 , MFC 细胞 , RPMI-1640 培养基
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New genetic insights into immunotherapy outcomes in gastric cancer via single-cell RNA sequencing and random forest model (2024-05-02)
期刊：CANCER IMMUNOLOGY IMMUNOTHERAPY
DOI：10.1007/s00262-024-03684-8
影响因子 ：5.8
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Gypenoside induces apoptosis by inhibiting the PI3K/AKT/mTOR pathway and enhances T-cell antitumor immunity by inhibiting PD-L1 in gastric cancer (2024-02-28)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1243353
影响因子 ：5.6
引用产品： HGC-27 细胞 , SGC-7901 细胞 , MFC 细胞
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Swertianin Promotes Anti-Tumor activity by facilitating Macrophage M1 polarization via STING signaling (2024-09-18)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113182
影响因子 ：4.8
引用产品： RAW 264.7 细胞 , 小鼠视网膜微血管内皮细胞 , MFC 细胞
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Ganodermanontriol regulates tumor-associated M2 macrophage polarization in gastric cancer (2024-01-19)
期刊：Aging-US
影响因子 ：3.9
引用产品： RAW 264.7 细胞 , RAW 264.7细胞专用培养基 , MFC 细胞
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Closed-loop of Catalyzed Lactate Oxidization Synergistically Sensitizes Apoptosis and Ferroptosis for Cancer Therapy (2024-02-01)
期刊：ChemNanoMat
影响因子 ：3.8
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System analysis based on T-cell exhaustion-related genes identifies PTPRT as a promising diagnostic and prognostic biomarker for gastric cancer (2024-09-09)
期刊：Scientific Reports
DOI：10.1038/s41598-024-72135-2
影响因子 ：3.8
引用产品： MFC 细胞
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CLEC4E upregulation in gastric cancer: A potential therapeutic target correlating with tumor-associated macrophages (2024-02-28)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e27172
影响因子 ：3.4
引用产品： MFC 细胞
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Akkermansia muciniphila improves gastric cancer treatment by modulating the immune microenvironment (2024-04-17)
期刊：Future Microbiology
影响因子 ：3.1
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KPNA2/KPNB1 promotes the malignant progression of gastric cancer induced by M2 macrophage polarization (2024-12-31)
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2024.102714
影响因子 ：2.7
引用产品： DMEM高糖完全培养基（含10% FBS） , MFC 细胞 , RPMI-1640 培养基
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A novel antidiuretic hormone governs tumour-induced renal dysfunction (2023-12-06)
期刊：NATURE
DOI：10.1038/s41586-023-06833-8
影响因子 ：64.8
引用产品： MFC 细胞 , B16 细胞 , HCT 116 细胞
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Oxyhaemoglobin saturation NIR-IIb imaging for assessing cancer metabolism and predicting the response to immunotherapy (2023-09-11)
期刊：Nature Nanotechnology
DOI：10.1038/s41565-023-01501-4
影响因子 ：38.3
引用产品： 4T1 细胞 , EMT6 [EMT-6] 细胞 , Renca [RenCa] 细胞 , LLC [LL/2; LLC1] 细胞 , CT26.WT 细胞 , MFC 细胞
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CHSY3 promotes proliferation and migration in gastric cancer and is associated with immune infiltration (2023-07-17)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04333-x
影响因子 ：7.4
引用产品： MFC 细胞
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Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway (2023-12-12)
期刊：Cell Death Discovery
DOI：10.1038/s41420-023-01752-z
影响因子 ：7.0
引用产品： MFC 细胞
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Efficacy of anti-programmed cell death protein 1 monoclonal antibody combined with bevacizumab and/or Pseudomonas aeruginosa injection in transplanted tumor of mouse forestomach carcinoma cell gastric cancer in mice and its mechanism in regulating tumor immune microenvironment (2023-07-01)
期刊：CLINICAL AND EXPERIMENTAL IMMUNOLOGY
影响因子 ：4.6
引用产品： MFC 细胞
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SUZ12 promotes the malignant behavior of gastric cancer cells by CDKs (2023-03-30)
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 ：3.6
引用产品： MFC 细胞
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m6A Reader YTHDF1-Targeting Engineered Small Extracellular Vesicles for Gastric Cancer Therapy via Epigenetic and Immune Regulation (2022-12-09)
期刊：ADVANCED MATERIALS
影响因子 ：32.1
引用产品： MFC 细胞
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Transfer of LncRNA CRNDE in TAM-derived exosomes is linked with cisplatin resistance in gastric cancer (2021-12-06)
期刊：Embo Reports
影响因子 ：9.1
引用产品： SGC-7901 细胞 , MFC 细胞
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Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages (2021-08-18)
期刊：Biomaterials Science
影响因子 ：6.6
引用产品： NCTC clone 929 [L 细胞, L-929] 细胞 , RAW 264.7 细胞 , MFC 细胞
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GC-Derived EVs Enriched with MicroRNA-675-3p Contribute to the MAPK/PD-L1-Mediated Tumor Immune Escape by Targeting CXXC4 (2020-08-21)
期刊：Molecular Therapy-Nucleic Acids
DOI：10.1016/j.omtn.2020.08.020
影响因子 ：8.8
引用产品： MFC 细胞
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