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产品概述
名称 | HGC-27 (人胃癌细胞(未分化)) (STR鉴定正确) |
别称 | HGC27 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | HGC-27细胞源自未分化胃癌组织,能分泌粘液素。 |
组织来源 | 胃,淋巴结转移 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胃癌细胞 |
倍增时间 | ~17 hours |
保藏机构 | BCRJ; 0310 ECACC; 94042256 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 22,24 D3S1358 17 D5S818 12 D7S820 11,12,13 D8S1179 11,16 D13S317 10,11 D16S539 10,11 D18S51 16,17 D19S433 14 D21S11 30,33,34 FGA 22 PentaD 9,13 PentaE 18 TH01 9 TPOX 8 vWA 14 D6S1043 18 D12S391 20,21 D2S441 9.1,13 -
STR鉴定图
参考文献
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AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination(2022/11/14)
作者:Zhao, Rou, He, Baoyu, Bie, Qingli, Cao, Jinghe, Lu, Haoran, Zhang, Zhixin, Liang, Jing, Wei, Li, Xiong, Huabao, Zhang, Bin
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-022-02532-w
影响因子 :11.300
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FLOT1 promotes gastric cancer progression and metastasis through BCAR1/ERK signaling(2023/10/02)
作者:Ran Wang, Wei Huang, Kaimei Cai
期刊:International Journal of Biological Sciences
影响因子 :9.200
引用产品:CL-0107
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miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling(2021/08/08)
作者:Lihui Zhang, Liwen Yao, Wei Zhou
期刊:Molecular Therapy-Nucleic Acids
DOI:10.1016/j.omtn.2021.07.025
影响因子 :8.800
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Neutrophil extracellular traps promote angiogenesis in gastric cancer(2023/07/21)
作者:Shifeng Yang, Boshi Sun, Jiacheng Li
期刊:Cell Communication and Signaling
DOI:10.1186/s12964-023-01196-z
影响因子 :8.400
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Self-Monitoring and Self-Delivery of Self-Assembled Fluorescent Nanoparticles in Cancer Therapy(2021/03/29)
作者:Hongmei Liu, Minghao Yuan, Yushi Liu
期刊:International Journal of Nanomedicine
影响因子 :8.000
引用产品:CL-0107
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CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1(2022/11/12)
作者:Li, Dongbao, Wang, Yuhong, Dong, Chao, Chen, Tao, Dong, Anqi, Ren, Jiayu, Li, Weikang, Shu, Gege, Yang, Jiaoyang, Shen, Wenhao, Qin, Lei, Hu, Lin, Zhou, Jin
期刊:ONCOGENE
DOI:10.1038/s41388-022-02537-x
影响因子 :8.000
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Compound Kushen Injection inhibits epithelial-mesenchymal transition of gastric carcinoma by regulating VCAM1 induced by the TNF signaling pathway(2023/07/17)
作者:Zhihong Huang, Chao Wu, Wei Zhou
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2023.154984
影响因子 :7.900
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A new strategy to identify ADAM12 and PDGFRB as a novel prognostic biomarker for matrine regulates gastric cancer via high throughput chip mining and computational verification(2023/10/11)
作者:Yifei Gao, Chao Wu, Jiaqi Huang
期刊:COMPUTERS IN BIOLOGY AND MEDICINE
DOI:10.1016/j.compbiomed.2023.107562
影响因子 :7.700
引用产品:CL-0107
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CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation(2024/03/08)
作者:Yongxin Zhang, Xiaofeng Wang, Wenwei Liu
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04625-2
影响因子 :7.400
引用产品:CL-0107
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Quercetin induces ferroptosis in gastric cancer cells by targeting SLC1A5 and regulating the p-Camk2/p-DRP1 and NRF2/GPX4 Axes(2024/01/06)
作者:Lixian Ding, Shuwei Dang, Mingjun Sun
期刊:FREE RADICAL BIOLOGY AND MEDICINE
DOI:10.1016/j.freeradbiomed.2024.01.002
影响因子 :7.400
引用产品:CL-0107
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Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer(2023/01/05)
作者:Hao Yang, Xinyi Gou, Caizhen Feng
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-022-03845-2
影响因子 :7.400
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Identification of lactylation related model to predict prognostic, tumor infiltrating immunocytes and response of immunotherapy in gastric cancer(2023/03/03)
作者:Hao Yang, Xiaoming Zou, Shifeng Yang
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1149989
影响因子 :7.300
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Effect of NETs/COX-2 pathway on immune microenvironment and metastasis in gastric cancer(2023/04/20)
作者:Ange Zhang, Xiaoming Zou, Shifeng Yang
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1177604
影响因子 :7.300
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RP11-789C1.1 inhibits gastric cancer cell proliferation and accelerates apoptosis via the ATR/CHK1 signaling pathway(2023/10/25)
作者:Wenwei Liu, Wei Feng, Yongxin Zhang
期刊:CHINESE MEDICAL JOURNAL
DOI:10.1097/CM9.0000000000002869
影响因子 :6.100
引用产品:CL-0107
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Glucose transporter 3 (GLUT3) promotes lactylation modifications by regulating lactate dehydrogenase A (LDHA) in gastric cancer(2023/12/01)
作者:Hao Yang, Shifeng Yang, Jixing He
期刊:Cancer Cell International
DOI:10.1186/s12935-023-03162-8
影响因子 :5.800
引用产品:CL-0107
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USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer(2024/01/17)
作者:Rongfu Tu, Ye Kang, Yiwen Pan
期刊:Cancer Cell International
DOI:10.1186/s12935-024-03224-5
影响因子 :5.800
引用产品:CL-0107
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Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma(2022/11/23)
作者:Yun Li, Jian-Bo Xiong, Zhi-Gang Jie, Hui Xiong
期刊:Frontiers in Oncology
影响因子 :5.738
引用产品:CL-0107
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DNMTs inhibitor Procyanidin B2 reactivates PTEN’s regulatory effects on abnormal glucose metabolism in gastric cancer(2024/02/08)
作者:Donghui Cao, Zhifang Jia, Yanhua Wu
期刊:Journal of Functional Foods
影响因子 :5.600
引用产品:CL-0107
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Asiaticoside promoted ferroptosis and suppressed immune escape in gastric cancer cells by downregulating the Wnt/β-catenin pathway(2024/05/10)
作者:Chenmin Ye, Zhichao Yao, Yaoyao Wang
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2024.112175
影响因子 :5.600
引用产品:CL-0107
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Gypenoside induces apoptosis by inhibiting the PI3K/AKT/mTOR pathway and enhances T-cell antitumor immunity by inhibiting PD-L1 in gastric cancer(2024/02/28)
作者:Hongliang Wu, Wenjing Lai, Qiaoling Wang
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2024.1243353
影响因子 :5.600
引用产品:CL-0107
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Identification of 14 Differentially-Expressed Metabolism-Related Genes as Potential Targets of Gastric Cancer by Integrated Proteomics and Transcriptomics(2022/02/21)
作者:Yongxin Zhang, Wenwei Liu, Wei Feng
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Long noncoding RNA PSMA3-AS1 functions as a competing endogenous RNA to promote gastric cancer progression by regulating the miR-329-3p/ALDOA axis(2023/07/04)
作者:Liang Kan, Meiqi Yang, Huijing Zhang
期刊:Biology Direct
DOI:10.1186/s13062-023-00392-8
影响因子 :5.500
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Gancao Xiexin Decoction inhibits gastric carcinoma proliferation and migration by regulating the JAK2/STAT3 signalling pathway(2023/09/28)
作者:Yating Yang, Ling Yuan, Fandi Meng
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.400
引用产品:CL-0107
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LINC01354 enhances the metastatic ability of gastric cancer cells by adjusting miR-153-5p/CADM2 expression(2023/06/15)
作者:Fa Fang, Yin Gu, Jie Gao
期刊:American Journal of Cancer Research
DOI:PMID:37424819
影响因子 :5.300
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Structural Characteristic, Strong Antioxidant, and Anti-Gastric Cancer Investigations on an Oleoresin from Ginger (Zingiber officinale var. roscoe)(2024/05/12)
作者:Meichun Chen, Enquan Lin, Rongfeng Xiao
期刊:Foods
影响因子 :5.200
引用产品:CL-0107
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ESM1 Interacts with c-Met to Promote Gastric Cancer Peritoneal Metastasis by Inducing Angiogenesis(2023/12/30)
作者:Jiaoyang Yang, Gege Shu, Tao Chen
期刊:Cancers
影响因子 :5.200
引用产品:CL-0107
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E2F5 promotes proliferation and invasion of gastric cancer through directly upregulating UBE2T transcription(2021/09/26)
作者:Lina Li, Jie Liu, Wei Huang
期刊:Digestive And Liver Disease
DOI:10.1016/+R32:W33j.dld.2021.09.003
影响因子 :5.165
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Identification of CERS5 as a molecular biomarker in pan-cancer through multiple omics integrative analysis(2024/01/18)
作者:Shengyu Wang, Jian Yang, Weijia Huang
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111054
影响因子 :4.800
引用产品:CL-0107
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Identification of specific modules and hub genes associated with the progression of gastric cancer(2019/10/16)
作者:Congcong Gong, Yang Hu, Mao Zhou
期刊:Carcinogenesis
影响因子 :4.700
引用产品:CL-0107
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miR-1304 targets KLK11 to regulate gastric cancer cell proliferation through the mTOR signaling pathway(2023/11/16)
作者:Yi Ding, Zehua Wang, Chen Chen
期刊:CARCINOGENESIS
影响因子 :4.700
引用产品:CL-0107
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The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11(2024/03/20)
作者:Qishuai Chen, Tongtong Zhang, Runzhi Zeng
期刊:Scientific Reports
DOI:10.1038/s41598-024-56746-3
影响因子 :4.600
引用产品:CL-0107
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Effects and mechanisms of trifluridine alone or in combination with cryptotanshinone in inhibiting malignant biological behavior of gastric cancer(2023/06/04)
作者:Panquan Luo, Lixiang Zhang, Zhangming Chen
期刊:CELL CYCLE
DOI:10.1080/15384101.2023.2215678
影响因子 :4.300
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Bile acids inhibit ferroptosis sensitivity through activating farnesoid X receptor in gastric cancer cells(2024/02/07)
作者:Chuxuan Liu, Ying Gao, Xiufang Xu
期刊:WORLD JOURNAL OF GASTROENTEROLOGY
影响因子 :4.300
引用产品:CL-0107
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18β-glycyrrhetinic acid inhibits proliferation of gastric cancer cells through regulating the miR-345-5p/TGM2 signaling pathway(2023/06/21)
作者:Xia Li, Xiaoling Ma, Yi Nan
期刊:WORLD JOURNAL OF GASTROENTEROLOGY
影响因子 :4.300
引用产品:CL-0107
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Gentiopicroside inhibits the progression of gastric cancer through modulating EGFR/PI3K/AKT signaling pathway(2024/01/11)
作者:Qishuai Chen, Tongtong Zhang, Bingjun Li
期刊:EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI:10.1186/s40001-024-01637-6
影响因子 :4.200
引用产品:CL-0107
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Cancer-associated fibroblast expression of glutamine fructose-6-phosphate aminotransferase 2 (GFPT2) is a prognostic marker in gastric cancer(2023/07/03)
作者:Shuo Yang, Guoli Li, Xin Yin
期刊:Journal of Pathology Clinical Research
DOI:10.1002/cjp2.333
影响因子 :4.100
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CIZ1 aggravates gastric cancer progression via mediating FBXL19-AS1 and miR-339-3p(2023/10/14)
作者:Houmin Wan, Lianzhen Wang, Bin Huo
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e21061
影响因子 :4.000
引用产品:CL-0107
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Suppression of gastric cancer cell proliferation by miR-494-3p inhibitor-loaded engineered exosomes(2024/05/06)
作者:Limin Zhang, Yingwei Xue, Hongfeng Zhang
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e30803
影响因子 :4.000
引用产品:CL-0107
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Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway(2022/03/02)
作者:Dong Tan, Yafei Zhang
期刊:Toxicology And Applied Pharmacology
DOI:10.1016/j.taap.2022.115968
影响因子 :3.800
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YTHDF2 promotes gastric cancer progression and enhances chemoradiotherapy resistance(2024/04/14)
作者:Jian Yang, Yawen Chen, Yang He
期刊:DRUG DEVELOPMENT RESEARCH
影响因子 :3.800
引用产品:CL-0107
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Unveiling DNA damage repair-based molecular subtypes, tumor microenvironment and pharmacogenomic landscape in gastric cancer(2023/04/14)
作者:Weiqi Kong, Zhiqiang Wang, Bingyi Wang
期刊:Frontiers in Genetics
DOI:10.3389/fgene.2023.1118889
影响因子 :3.700
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Circular RNA Circ_0006282 Promotes Cell Proliferation and Metastasis in Gastric Cancer by Regulating MicroRNA-144-5p/Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein β Axis(2022/12/21)
作者:Yunqi Hua, Hailong Wang, Haizhen Wang
期刊:Cancer Management and Research
影响因子 :3.602
引用产品:CL-0107
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WYC-209 inhibited GC malignant progression by down-regulating WNT4 through RARα(2024/01/04)
作者:Zhenyuan Qian, Wenfa Lin, Xufan Cai
期刊:CANCER BIOLOGY & THERAPY
DOI:10.1080/15384047.2023.2299288
影响因子 :3.600
引用产品:CL-0107
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PKNOX1 acts as a transcription factor of DHH and promotes the progression of stomach adenocarcinoma by regulating the Hedgehog signalling pathway(2023/10/21)
作者:Bing Liu, Siwei Zhao, Liqing Liu
期刊:INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
影响因子 :3.500
引用产品:CL-0107
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Circ_0000419 acts as a tumor suppressor in gastric cancer development via regulating miR-300/RGMB axis(2023/07/20)
作者:Jiajun Lu, Yuan Zhou, Zhiheng Chen
期刊:International Journal of Clinical Oncology
DOI:10.1007/s10147-023-02379-x
影响因子 :3.300
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Celastrus orbiculatus extract suppresses gastric cancer stem cells through the TGF-β/Smad signaling pathway(2023/10/10)
作者:Tengyang Ni, Zewen Chu, Li Tao
期刊:Journal of Natural Medicines
DOI:10.1007/s11418-023-01748-0
影响因子 :3.300
引用产品:CL-0107
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Circular RNA Circ_0006282 Promotes Cell Proliferation and Metastasis in Gastric Cancer by Regulating MicroRNA-144-5p/Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein β Axis(2021/1/27)
作者:Yunqi Hua, Hailong Wang, Haizhen Wang
期刊:Cancer Management and Research
影响因子 :3.300
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Circ_0026359 induces HOXA9 to regulate gastric cancer malignant progression through miR-140-3p(2022/08/22)
作者:Shuirong Lu, Jinlai Lu, Lang Liu
期刊:Applied Biological Chemistry
DOI:10.1186/s13765-022-00726-6
影响因子 :3.200
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Circ_0003159 upregulates LIFR expression through competitively binding to miR-221-3p/miR-222-3p to block gastric cancer development(2022/01/16)
作者:Liansheng Zheng, Boshi Yan, Guoliang Jin
期刊:Journal Of Molecular Histology
DOI:10.1007/s10735-021-10044-8
影响因子 :3.200
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The GLI2/CDH6 axis enhances migration, invasion and mitochondrial fission of stomach adenocarcinoma cells(2023/07/24)
作者:Guangyi Liu, Huan Wang, Rui Ran
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.07.038
影响因子 :3.100
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Lidocaine Suppresses Gastric Cancer Development Through Circ_ANO5/miR-21-5p/LIFR Axis(2021/5/29)
作者:Enjian Guan, Hongrong Liu, Ning Xu
期刊:Digestive Diseases And Sciences
DOI:10.1007/s10620-021-07055-6
影响因子 :3.100
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Akkermansia muciniphila improves gastric cancer treatment by modulating the immune microenvironment(2024/04/17)
作者:Jianming Fang, Huizhong Zhang, Xiaodong Zhang
期刊:Future Microbiology
影响因子 :3.100
引用产品:CL-0107
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Chrysophanol induces apoptosis and ferroptosis of gastric cancer cells by targeted regulation of mTOR(2024/01/07)
作者:Sujuan Xi, Wei Ding, Danping Weng
期刊:Chemical Biology & Drug Design
影响因子 :3.000
引用产品:CL-0107
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Amentoflavone attenuates cell proliferation and induces ferroptosis in human gastric cancer by miR-496/ATF2 axis(2023/07/16)
作者:Fengying Tang, Yongpan Xu, Erpeng Gao
期刊:Chemical Biology & Drug Design
影响因子 :3.000
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Sinomenine regulates circTRPM7-related pathway to inhibit gastric cancer cell growth and metastasis(2023/07/26)
作者:Jingwei Yan, Jingqing Yang, Huifen Shen
期刊:Chemical Biology & Drug Design
影响因子 :3.000
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Mechanism of pachymic acid in the treatment of gastric cancer based on network pharmacology and experimental verification(2024/01/15)
作者:Yuhua Du, Jianjun Zhao, Xia Li
期刊:World Journal of Gastrointestinal Oncology
影响因子 :3.000
引用产品:CL-0107
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Natural Bioactive Compounds Promote Cell Apoptosis in Gastric Cancer Treatment: Evidence from Network Pharmacological Study and Experimental Analysis(2023/02/06)
作者:Yan Wang, Haiyang Wang, Shun Xu
期刊:Journal of Chemistry
影响因子 :3.000
引用产品:CL-0107
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Immune-related long noncoding RNA zinc finger protein 710-AS1-201 promotes the metastasis and invasion of gastric cancer cells(2024/02/15)
作者:Wei Ding, Weiwei Chen, Yiqin Wang
期刊:World Journal of Gastrointestinal Oncology
影响因子 :3.000
引用产品:CL-0107
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Knockdown of Serum- and Glucocorticoid-Regulated Kinase 1 Enhances Cisplatin Sensitivity of Gastric Cancer Through Suppressing the Nuclear Factor Kappa-B Signaling Pathway.(2021/11/01)
作者:Jishui Zhang, Wenhao Lv, Yagang Liu
期刊:Balkan Medical Journal
DOI:10.5152/balkanmedj.2021.21114
影响因子 :3.000
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Nuclear factor‑κB inhibitor Bay11‑7082 inhibits gastric cancer cell proliferation by inhibiting Gli1 expression(2021/2/17)
作者:Yan Yan, Heya Qian, Ying Cao
期刊:Oncology Letters
影响因子 :2.900
引用产品:CL-0107
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E2F1-mediated up-regulation of TOP2A promotes viability, migration, and invasion, and inhibits apoptosis of gastric cancer cells(2022/12/18)
作者:Yu Chen, Yong Yu, Miaomiao Lv
期刊:JOURNAL OF BIOSCIENCES
DOI:10.1007/s12038-022-00322-2
影响因子 :2.900
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A prognostic marker LTBP1 is associated with epithelial mesenchymal transition and can promote the progression of gastric cancer(2024/02/15)
作者:Xinju Jiang, Shengjie Yin, Xin Yin
期刊:FUNCTIONAL & INTEGRATIVE GENOMICS
DOI:10.1007/s10142-024-01311-4
影响因子 :2.900
引用产品:CL-0107
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KBTBD2 promotes proliferation and migration of gastric cancer via activating EGFR signaling pathway(2024/01/04)
作者:Jishuang Ding, Wei Gao, Haiying Yang
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.800
引用产品:CL-0107
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Knockdown circZNF131 Inhibits Cell Progression and Glycolysis in Gastric Cancer Through miR-186-5p/PFKFB2 Axis(2022/01/21)
作者:Xingjie Shen, Xiaoyan Zhu, Peixin Hu
期刊:Biochemical Genetics
DOI:10.1007/s10528-021-10165-5
影响因子 :2.400
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Circular RNA circ_0001017 Sensitizes Cisplatin-Resistant Gastric Cancer Cells to Chemotherapy by the miR-543/PHLPP2 Axis(2021/7/27)
作者:Jianmin Zhang, Wenzhang Zha, Changchun Qian
期刊:Biochemical Genetics
DOI:10.1007/s10528-021-10110-6
影响因子 :2.400
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Exosomal circPRRX1 functions as a ceRNA for miR-596 to promote the proliferation, migration, invasion, and reduce radiation sensitivity of gastric cancer cells via the upregulation of NF-κB activating protein(2022/10/05)
作者:Yuxin He, Liangjian Zheng, Mengzhen Yuan
期刊:ANTI-CANCER DRUGS
DOI:10.1097/CAD.0000000000001358
影响因子 :2.300
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Curcumin suppresses the progression of gastric cancer by regulating circ_0056618/miR-194-5p axis(2021/1/1)
作者:Shan Li, Lihai Zhang, Shuhua Li
期刊:Open Life Sciences
影响因子 :2.200
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Elevated mRNA level indicates FSIP1 promotes EMT and gastric cancer progression by regulating fibroblasts in tumor microenvironment(2024/05/10)
作者:Yao Liu, Xinju Jiang, Xiuchun Yan
期刊:Open Medicine
影响因子 :2.100
引用产品:CL-0107
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Circular RNA circ_SKA3 enhances gastric cancer development by targeting miR-520h(2022/09/22)
作者:Chuntao Wang, Hao Jiang, Jiaqun Peng
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.000
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