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产品概述
名称 | NB4 (人急性早幼粒细胞白血病细胞) (STR鉴定正确) |
别称 | NB-4; NB.4 |
种属 | 人 |
生长特性 | 悬浮细胞 |
细胞形态 | 淋巴母细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐换液频率 | 2-3次/周 |
背景描述 | NB-4细胞系源自1989年第二次复发的急性早幼粒细胞白血病(APL = AML FAB M3)患者的骨髓。 |
年龄(性别) | 女性;23岁 |
组织来源 | 骨髓 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 白血病细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~35-45 hours |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 20,25 D3S1358 15,17 D5S818 13 D7S820 10,13 D8S1179 10,14 D13S317 11,12 D16S539 9 D18S51 12 D19S433 15 D21S11 28,33.2 FGA 21,22 PentaD 10,13 PentaE 7,13 TH01 7,9.3 TPOX 8,11 vWA 16,19 D6S1043 12 D12S391 19,22 D2S441 10,14 -
STR鉴定图
参考文献
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BATF promotes extramedullary infiltration through TGF-β1/Smad/MMPs axis in acute myeloid leukemia (2024-03-13)
作者:Ru Zhang:1.Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Jiyu Miao:1.Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Meng Zhai:1.Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Rui Liu:1.Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Fangmei Li:1.Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Xuezhu Xu:1.Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Lingjuan Huang:1.Department of Geriatrics, The First Affiliated Hospital of Xi'an Medical University, Xi'an, China. ; Ting Wang:1.Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Rui Yang:1.Department of Hematology, The Second Affiliated Hospital of
期刊:BATF promotes extramedullary infiltration through TGF-β1/Smad/MMPs axis in acute myeloid leukemia
DOI:10.1002/mc.23715
影响因子 :4.6
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Integrated analysis and validation reveal CYTH4 as a potential prognostic biomarker in acute myeloid leukemia (2024-01-16)
作者:Hong Wang:1.Central Laboratory, Shenzhen University General Hospital, Shenzhen, Guangdong 518071, P.R. China. ; 2.Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen, Guangdong 518060, P.R. China. ; Yishu Xiao:1.Central Laboratory, Shenzhen University General Hospital, Shenzhen, Guangdong 518071, P.R. China. ; Wei Zhou:1.Central Laboratory, Shenzhen University General Hospital, Shenzhen, Guangdong 518071, P.R. China. ; 2.Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen, Guangdong 518060, P.R. China. ; Yonghui Li:1.Central Laboratory, Shenzhen University General Hospital, Shenzhen, Guangdong 518071, P.R. China. ; 2.Guan
期刊:Integrated analysis and validation reveal CYTH4 as a potential prognostic biomarker in acute myeloid leukemia
影响因子 :2.9
引用产品: NOMO-1 细胞 , MOLM-13 细胞 , NB4 细胞 , BALL-1 细胞 , NALM-6 细胞 , SUP-B15 细胞
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Apicidin confers promising therapeutic effect on acute myeloid leukemia cells via increasing QPCT expression (2023-06-28)
作者:Lulu Liu:1.Medical Research Center, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Haihui Liu:1.Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Lei Liu:1.Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Qian Huang:1.Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Chunyan Yang:1.Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Panpan Cheng:1.Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Saisai Ren:1.Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Jingjing Zhang:1.Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China. ; Mingxiao Yu:1.Department of Graduate School, Jining Medical Un
期刊:Apicidin confers promising therapeutic effect on acute myeloid leukemia cells via increasing QPCT expression
DOI:10.1080/15384047.2023.2228497
影响因子 :3.6
引用产品: NB4 细胞
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Circ_0001602 aggravates the progression of acute myeloid leukemia by regulating the miR-192-5p/ZBTB20 axis (2023-08-10)
作者:Weihao Wu:1.Department of Hematology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan City, People's Republic of China. ; Jiayi Deng:1.Department of Hematology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan City, People's Republic of China. ; Congjie Chen:1.Department of Hematology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan City, People's Republic of China. ; Xiaomei Ma:1.Department of Hematology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan City, People's Republic of China. ; Lian Yu:1.Department of Hematology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan City, People's Republic of China. ; Longtian Chen:1.Department of Hematology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan City, People's Republic of China. ;
期刊:Circ_0001602 aggravates the progression of acute myeloid leukemia by regulating the miR-192-5p/ZBTB20 axis
DOI:10.1080/16078454.2023.2240133
影响因子 :1.9
引用产品: THP-1 细胞 , HL-60 细胞 , NB4 细胞 , 293T [HEK-293T] 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , IMDM 培养基 , RPMI-1640 培养基
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Exploration of differentially expressed mRNAs and miRNAs for pediatric acute myeloid leukemia (2022-09-06)
作者:Qing Wang:1.Department of Clinical Laboratory, The General Hospital of Tianjin Medical University, Tianjin, China. ; Chao Yue:1.Department of Blood Transfusion, The Fifth Central Hospital of Tianjin, Tianjin, China. ; Qin Liu:1.Department of Clinical Laboratory, The Fifth Central Hospital of Tianjin, Tianjin, China. ; Xuchun Che:1.Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Educational Ministry of China, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. ;
期刊:Exploration of differentially expressed mRNAs and miRNAs for pediatric acute myeloid leukemia
影响因子 :4.8
引用产品: NB4 细胞
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