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产品概述
名称 | BxPC-3 (人原位胰腺腺癌细胞) (STR鉴定正确) |
别称 | BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3; Biopsy xenograft of Pancreatic Carcinoma line-3 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:6 |
推荐换液频率 | 2-3次/周 |
背景描述 | BxPC-3细胞不表达囊肿性纤维化跨膜电导调节子(CFTR),CFTR阳性的细胞株是Capan-1。 |
年龄(性别) | 女性;61岁 |
组织来源 | 胰腺;腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胰腺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~48-60 hours |
致瘤性 | Yes, Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells. |
基因表达情况 | mucin; pancreas cancer specific antigen (pancreas cancer associated antigen); carcinoembryonic antigen (CEA) |
保藏机构 | ATCC; CRL-1687 BCRC; 60283 BCRJ; 0056 DSMZ; ACC-760 ECACC; 93120816 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 13 D2S1338 17,19 D3S1358 14,16 D5S818 11 D7S820 10,13 D8S1179 13 D13S317 11 D16S539 9,11 D18S51 12 D19S433 13,16.2 D21S11 29 FGA 20,21 PentaD 14 PentaE 12,14 TH01 9 TPOX 8 vWA 14,18 D6S1043 12 D12S391 19.3,20 D2S441 12,14 -
STR鉴定图
参考文献
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HMGA2 alleviates ferroptosis by promoting GPX4 expression in pancreatic cancer cells (2024-03-16)
作者:Ziyang Luo:1.Department of Biochemistry and Molecular Biology and Zhejiang Key Laboratory of Pathophysiology, School of Basic Medical Sciences, Health Science Center, Ningbo University, Ningbo, 315211, China. ; Qingfang Zheng:1.Department of Biochemistry and Molecular Biology and Zhejiang Key Laboratory of Pathophysiology, School of Basic Medical Sciences, Health Science Center, Ningbo University, Ningbo, 315211, China. ; Shazhou Ye:1.Department of Biochemistry and Molecular Biology and Zhejiang Key Laboratory of Pathophysiology, School of Basic Medical Sciences, Health Science Center, Ningbo University, Ningbo, 315211, China. ; Yanguo Li:1.Institute of Drug Discovery Technology, Ningbo University, Ningbo, 315211, China. ; Jiayi Chen:1.Department of Biochemistry and Molecular Biology and Zhejiang Key Laboratory of Pathophysiology, School of Basic Medical Sciences, Health Science Center, Ningbo University, Ningbo, 315211, China. ; Chengjiang Fan:1.Department of Biochemistry and Mol
期刊:HMGA2 alleviates ferroptosis by promoting GPX4 expression in pancreatic cancer cells
DOI:10.1038/s41419-024-06592-y
影响因子 :9.0
引用产品: PANC-1 细胞 , MIA PaCa-2 细胞 , BxPC-3 细胞
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Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2 (2024-01-26)
作者:Hao Yang:1.Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. ; Zhongyi Li:1.Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Munich, Germany. ; Shiqi Zhu:1.Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. ; Wenxia Wang:1.Department of General Medicine, Zhongshan Hospital Fudan University, Shanghai, China. ; Jing Zhang:1.Division of Basic Biomedical Sciences, The University of South Dakota Sanford School of Medicine, Vermillion, SD, United States. ; Dongxu Zhao:1.Department of Interventional Radiology, The Affiliated Changshu Hospital of Nantong University, Changshu No. 2 People's Hospital, Changshu, Jiangsu, China. ; Man Zhang:1.Department of Emergency Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China. ; Wenxin Zhu:1.Department of Gastroenterology, Kunshan Third People's Hospital,
期刊:Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2
DOI:10.3389/fimmu.2024.1347683
影响因子 :7.3
引用产品: PANC-1 细胞 , BxPC-3 细胞 , RPMI-1640 培养基
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LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4 (2024-03-19)
作者:Zhenchong Li:1.Department of General Surgery, Heyuan people's Hospital, Heyuan, 517000, China. ; 2.Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. ; 3.Junior Clinical Cooperation Unit Translational Gastrointestinal Oncology and Preclinical Models, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. ; Zuyi Ma:1.Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China. ; Shujie Wang:1.The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong Province, 510515, China. ; Qian Yan:1.Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. ; 2.South China Univer
期刊:LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4
DOI:10.1186/s13062-024-00463-4
影响因子 :5.5
引用产品: PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞 , AsPC-1 细胞 , SW 1990 细胞 , HPED-6 细胞
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GPX3 represses pancreatic cancer cell proliferation, migration and invasion, and improves their chemo‑sensitivity by regulating the JNK/c‑Jun signaling pathway (2024-01-29)
作者:Ye Ma:1.Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China. ; 2.Department of General Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu 215008, P.R. China. ; Lixing Zhang:1.Medical Laboratory, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163, P.R. China. ; Xin Gao:1.Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China. ; Dongming Zhu:1.Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China. ;
期刊:GPX3 represses pancreatic cancer cell proliferation, migration and invasion, and improves their chemo‑sensitivity by regulating the JNK/c‑Jun signaling pathway
影响因子 :2.7
引用产品: BxPC-3 细胞 , SW 1990 细胞 , PANC-1 细胞
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Accurate Visualization of Metabolic Aberrations in Cancer Cells by Temperature Mapping with Quantum Coherence Modulation Microscopy (2023-04-27)
作者:Haitao Zhou:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Collaborative Innovation Center of Molecular Imaging Precision Medical, Taiyuan, Shanxi 030001, China. ; Wei Yao:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Collaborative Innovation Center of Molecular Imaging Precision Medical, Taiyuan, Shanxi 030001, China. ; Xiaotong Zhou:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Collaborative Innovation Center of Molecular Imaging Precision Medical, Taiyuan, Shanxi 030001, China. ; Shuai Dong:1.State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, Shanxi 030006, China. ; Ruonan Wang:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Collaborative Innovation Center of Molecular Imaging Precision Medical, Taiyuan, Shanxi
期刊:Accurate Visualization of Metabolic Aberrations in Cancer Cells by Temperature Mapping with Quantum Coherence Modulation Microscopy
影响因子 :17.1
引用产品: A549 [A-549] 细胞 , Hela 细胞 , Hep G2 细胞 , BxPC-3 细胞 , DU 145 细胞 , 4T1 细胞 , BEAS-2B 细胞 , MET-5A 细胞 , 潮霉素B溶液 (50mg/mL)
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Radionuclide labeled nanocarrier for imaging guided combined radionuclide, sonodynamic, and photothermal therapy of pancreatic tumours (2023-03-30)
作者:Jie An:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Molecular Imaging Precision Medical Collaborative Innovation Center, Shanxi Medical University, Taiyuan 030001, Shanxi Province, PR China. ; Xinyi He:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Molecular Imaging Precision Medical Collaborative Innovation Center, Shanxi Medical University, Taiyuan 030001, Shanxi Province, PR China. ; Huizhu Ma:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Molecular Imaging Precision Medical Collaborative Innovation Center, Shanxi Medical University, Taiyuan 030001, Shanxi Province, PR China. ; Yanglei Li:1.Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Molecular Imaging Precision Medical Collaborative Innovation Center, Shanxi Medical University, Taiyuan 030001, Shanxi Province, PR China. ; Yayuan Li:1.Department of Nuclear Medicine, The First Hospital
期刊:Radionuclide labeled nanocarrier for imaging guided combined radionuclide, sonodynamic, and photothermal therapy of pancreatic tumours
DOI:10.1016/j.jcis.2023.03.111
影响因子 :9.9
引用产品: BxPC-3 细胞
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pH-Sensitive Biomimetic Nanosystem Based on Large-Pore Mesoporous Silica Nanoparticles with High Hyaluronidase Loading for Tumor Deep Penetration (2023-08-05)
作者:Xiaojie Song:1.School of Life Sciences, Zhengzhou University, Science Avenue 100#, Zhengzhou 450001, China. ; Chun-Ling Li:1.School of Life Sciences, Zhengzhou University, Science Avenue 100#, Zhengzhou 450001, China. ; Nan Qiu:1.School of Life Sciences, Zhengzhou University, Science Avenue 100#, Zhengzhou 450001, China. ; Qi-Yan Lv:1.School of Life Sciences, Zhengzhou University, Science Avenue 100#, Zhengzhou 450001, China. ; Xinxin Wu:1.Department of Molecular Pathology, Henan Cancer Hospital, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450001, China. ; Hui-Fang Cui:1.School of Life Sciences, Zhengzhou University, Science Avenue 100#, Zhengzhou 450001, China. ;
期刊:pH-Sensitive Biomimetic Nanosystem Based on Large-Pore Mesoporous Silica Nanoparticles with High Hyaluronidase Loading for Tumor Deep Penetration
影响因子 :9.5
引用产品: BxPC-3 细胞
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METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation (2023-03-28)
作者:Chengjie Lin:1.Department of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350001, China. ; 2.Fujian Abdominal Surgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350001, China. ; 3.National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350212, China. ; Ting Li:1.Department of Oncology, Fujian Provincial Hospital, Provincial Clinical College of Fujian Medical University, Fuzhou, Fujian, 350001, China. ; Yan Wang:1.Department of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350001, China. ; 2.Fujian Abdominal Surgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350001, China. ; 3.National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fu
期刊:METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation
DOI:10.1038/s41419-023-05715-1
影响因子 :9.0
引用产品: SW 1990 细胞 , PANC-1 细胞 , BxPC-3 细胞
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Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer (2023-08-03)
作者:Jinfeng Zhu:1.Jiangxi Province Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ; Hong Teng:1.Jiangxi Province Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ; 2.Department of Medical Genetics, The Second Affiliated Hospital of Nanchang University, Nanchang, China. ; 3.School of Public Health, Nanchang University, Nanchang, Jiangxi, China. ; Xiaojian Zhu:1.Tomas Lindahl Nobel Laureate Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China. ; Jingxuan Yuan:1.Jiangxi Province Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ; 2.Department of Medical Genetics, The Second Affiliated Hospital of Nanchang University, Nanchang, China. ; 3.School of Public Health, Nanchang University, Nanchang, Jiangxi, China. ; Qiong Zhang:1.Jiangxi Province Key Lab
期刊:Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer
DOI:10.3389/fimmu.2023.1167018
影响因子 :7.3
引用产品: BxPC-3 细胞
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Crosstalk of ferroptosis regulators and tumor immunity in pancreatic adenocarcinoma: novel perspective to mRNA vaccines and personalized immunotherapy (2023-06-27)
作者:Yanlong Shi:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Yizhu Wang:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Hui Dong:1.School of Medicine, Southeast University, 210009, Nanjing, China. ; Kaiyi Niu:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Wenning Zhang:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Kun Feng:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Rui Yang:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Yewei Zhang:1.H
期刊:Crosstalk of ferroptosis regulators and tumor immunity in pancreatic adenocarcinoma: novel perspective to mRNA vaccines and personalized immunotherapy
DOI:10.1007/s10495-023-01868-8
影响因子 :7.2
引用产品: HPNE 细胞 , CFPAC-1 细胞 , SW 1990 细胞 , BxPC-3 细胞
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5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis (2023-10-12)
作者:Wenpeng Cao:1.Department of Anatomy, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Zhirui Zeng:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Shan Lei:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ;
期刊:5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis
影响因子 :5.5
引用产品: MIA PaCa-2 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , Capan-2 细胞 , SW 1990 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , 人胰腺上皮细胞
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RBM15 Promates the Proliferation, Migration and Invasion of Pancreatic Cancer Cell Lines (2023-02-08)
作者:Hui Dong:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Haidong Zhang:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Xinyu Mao:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China. ; Shiwei Liu:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Wenjing Xu:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Yewei Zhang:1.School of Medicine, Southeast University, Nanjing 210009, China. ; 2.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China. ;
期刊:RBM15 Promates the Proliferation, Migration and Invasion of Pancreatic Cancer Cell Lines
影响因子 :5.2
引用产品: HPNE 细胞 , CFPAC-1 细胞 , BxPC-3 细胞
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COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation (2023-02-26)
作者:Yao Song:1.Department of Radiotherapy and Oncology, Affiliated Hospital of Nantong University, Nantong 226001, China. ; 2.Department of Radiation Oncology, Tenth People's Hospital Afflfliated to Tongji University, Shanghai 200072, China. ; Lei Wang:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; Kaidong Wang:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; Yuhua Lu:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; Pengcheng Zhou:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; 2.Department of Surgery, Medical School, Southeast University, Nanjing 210009, China. ;
期刊:COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation
影响因子 :5.2
引用产品: PANC-1 细胞 , BxPC-3 细胞 , CFPAC-1 细胞 , PATU8988 细胞 , AsPC-1 细胞 , MIA PaCa-2 细胞
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Aberrant expression of PELI1 caused by Jagged1 accelerates the malignant phenotype of pancreatic cancer (2023-08-30)
作者:Wenyang Zhou:1.Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. ; Yuying Hu:1.Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. ; Baosheng Wang:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Lina Yuan:1.Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. ; Jia Ma:1.Department of Gastroenterology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China. Electronic address: dorothy_mj@126.com. ; Xiangpeng Meng:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. Electronic address: mengxpcmu@126.com. ;
期刊:Aberrant expression of PELI1 caused by Jagged1 accelerates the malignant phenotype of pancreatic cancer
DOI:10.1016/j.cellsig.2023.110877
影响因子 :4.8
引用产品: BxPC-3 细胞 , IMDM 培养基 , SW 1990细胞专用培养基 (L15)
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Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer (2023-10-24)
作者:Xu Chen:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; 2.Laboratory of Integrative Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Qihang Yuan:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Hewen Guan:1.Department of Dermatology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Xueying Shi:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; 2.Laboratory of Integrative Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Jiaao Sun:1.Department of Urology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Zhiqiang Wu:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ;
期刊:Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer
影响因子 :4.7
引用产品: BxPC-3 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , MIA PaCa-2 细胞
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Tartary buckwheat root polysaccharides ameliorate non-alcoholic fatty liver disease via the IL6-SOCS3-SREBP1c pathway (2023-08-19)
作者:Litao Zhang:1.School of Biological Science, Jining Medical University, Rizhao, Shandong, 276826, China. ; Shuo Wang:1.School of Biological Science, Jining Medical University, Rizhao, Shandong, 276826, China. ; Yimin Li:1.Department of Pharmacy, Jining Medical University, Rizhao, Shandong, 276826, China. ; Boyu Liu:1.School of Biological Science, Jining Medical University, Rizhao, Shandong, 276826, China. ; Zeyu Duan:1.School of Biological Science, Jining Medical University, Rizhao, Shandong, 276826, China. ; Fei Liu:1.School of Biological Science, Jining Medical University, Rizhao, Shandong, 276826, China. ; Qiang Ren:1.Department of Pharmacy, Jining Medical University, Rizhao, Shandong, 276826, China. Electronic address: renqiang@mail.jnmc.edu.cn. ;
期刊:Tartary buckwheat root polysaccharides ameliorate non-alcoholic fatty liver disease via the IL6-SOCS3-SREBP1c pathway
影响因子 :4.3
引用产品: Hep G2 细胞 , BEL-7404 细胞 , BxPC-3 细胞
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Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis (2023-10-30)
作者:Zemin Zhu:1.Department of Hepatobiliary and Pancreatic Surgery, Zhuzhou Central Hospital, Zhuzhou, China. ; Bo Yi:1.Department of Hepatobiliary and Pancreatic Surgery, Zhuzhou Central Hospital, Zhuzhou, China. ; Zikai Tang:1.Department of Hepatobiliary and Pancreatic Surgery, Zhuzhou Central Hospital, Zhuzhou, China. ; Xun Chen:1.Department of Hepatobiliary and Pancreatic Surgery, Zhuzhou Central Hospital, Zhuzhou, China. ; 2.Department of Trauma Center, Zhuzhou Central Hospital, Zhuzhou, China. ; Ming Li:1.Department of Trauma Center, Zhuzhou Central Hospital, Zhuzhou, China. ; Tao Xu:1.Department of Hepatobiliary and Pancreatic Surgery, Zhuzhou Central Hospital, Zhuzhou, China. ; Zhijian Zhao:1.Department of Hepatobiliary and Pancreatic Surgery, Zhuzhou Central Hospital, Zhuzhou, China. zxyyzzj63@163.com. ; Caixi Tang:1.Department of Hepatobiliary and Pancreatic Surgery, Zhuzhou Central Hospital, Zhuzhou, China. tcx0864@163.com. ; 2.Department of Trauma Center, Zhuzhou Central
期刊:Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis
DOI:10.1186/s12885-023-11557-z
影响因子 :3.8
引用产品: MIA PaCa-2 细胞 , PANC-1 细胞 , AsPC-1 细胞 , BxPC-3 细胞 , THP-1 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , 特级胎牛血清 , 马血清 , 青霉素-链霉素溶液 (双抗),100× , β-巯基乙醇 (55mM),1000×
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Preparation and Characterization of PLGA-based Magnetic Polymer Nanoparticles for Targeting Pancreatic Adenocarcinoma (2023-03-01)
作者:Liangji Lu:1.Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China. ; Liyong Jie:1.Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China. ; Ying Zhou:1.College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China. ; Jiaojiao Zhang:1.College of Food and Health, Zhejiang A&F University, Hangzhou, 311300, China. ; Tingting Feng:1.College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China. ; Yue Zhu:1.College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China. ; 2.Nano-drug Technology Research Center of Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China. ; Teng Chen:1.College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China. ; 2.Nan
期刊:Preparation and Characterization of PLGA-based Magnetic Polymer Nanoparticles for Targeting Pancreatic Adenocarcinoma
DOI:10.2174/1381612829666230324091555
影响因子 :3.1
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Comprehensive pan-cancer analysis of role of GPRASP1, associated with clinical outcomes, immune microenvironment, and immunotherapeutic efficiency in pancreatic cancer (2023-02-12)
作者:Jiaxing Du:1.Department of Surgical Oncology, Xinyang Central Hospital, Xinyang 464000, Henan Province, PR China. Electronic address: djx13131313@126.com. ; Yongsheng Chen:1.Department of Radiation Oncology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong Province, PR China. Electronic address: 318483790@qq.com. ; Genglong Liu:1.Department of Pathology, Shunde Hospital, Southern Medical University (The First people's hospital of Shunde), Foshan 528308, Guangdong Province, PR China; Baishideng Publishing Group Inc, Pleasanton, CA 94566, United States. Electronic address: lglong3@mail2.sysu.edu.cn. ; Qingxing Zeng:1.Department of Intensive Care Unit, Xinyang Central Hospital, Xinyang 464000, Henan Province, PR China. Electronic address: gszengxing@163.com. ; Nan Zhou:1.Department of Surgical Oncology, Xinyang Central Hospital, Xinyang 464000, Henan Province, PR China. Electronic address: ntzhounan@126.com. ; Dajun Du:1.Department o
期刊:Comprehensive pan-cancer analysis of role of GPRASP1, associated with clinical outcomes, immune microenvironment, and immunotherapeutic efficiency in pancreatic cancer
影响因子 :2.8
引用产品: PANC-1 细胞 , MIA PaCa-2 细胞 , BxPC-3 细胞 , SW 1990 细胞 , AsPC-1 细胞
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The DEAD-box RNA helicase, DDX60, Suppresses immunotherapy and promotes malignant progression of pancreatic cancer (2023-05-26)
作者:Tiantian Lai:1.Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Jiangnan University, Wuxi, 214122, Jiangsu Province, China. ; 2.Wuxi Medical College, Jiangnan University, Wuxi, 214122, Jiangsu Province, China. ; Xiaowen Su:1.Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Jiangnan University, Wuxi, 214122, Jiangsu Province, China. ; 2.Wuxi Medical College, Jiangnan University, Wuxi, 214122, Jiangsu Province, China. ; Enhong Chen:1.Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Jiangnan University, Wuxi, 214122, Jiangsu Province, China. ; Yue Tao:1.Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Jiangnan University, Wuxi, 214122, Jiangsu Province, China. ; 2.Wuxi Medical College, Jiangnan University, Wuxi, 214122, Jiangsu Province, China. ; Shuo Zhang:1.Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Jiangnan University, Wuxi, 214122, Jiangsu Provinc
期刊:The DEAD-box RNA helicase, DDX60, Suppresses immunotherapy and promotes malignant progression of pancreatic cancer
DOI:10.1016/j.bbrep.2023.101488
影响因子 :2.7
引用产品: BxPC-3 细胞
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Synthesis of Copper and Cobalt complexes with a Hydrothermal Method and Their Applications in Antibiological Activity (2023-12-01)
作者:The Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry, Center of Physical Chemistry Test, Shenyang University of Chemical Technology, 110142 Shenyang, P. R. China
期刊:Synthesis of Copper and Cobalt complexes with a Hydrothermal Method and Their Applications in Antibiological Activity
影响因子 :2.1
引用产品: BxPC-3 细胞
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Biomimetic camouflaged nanoparticle-based folfirinox platform for optimizing clinical pancreatic cancer treatment (2022-12-21)
作者:Qian Wang: 1.Department of Diagnostic Imaging, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China;2.Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China; Zihua Wang: 1.Fujian Provincial Key Laboratory of Brain Aging and Neurodegenerative Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350122, China; Zhangfu Li: 1.Department of Hepato-Pancreato-Biliary Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, Guangzhou 518036, China; Dan Li: 1.State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China; Fangfei He: 1.CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanoma
期刊:Biomimetic camouflaged nanoparticle-based folfirinox platform for optimizing clinical pancreatic cancer treatment
DOI:10.1016/j.nantod.2022.101733
影响因子 :19.0
引用产品: BxPC-3 细胞
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Albumin binding revitalizes NQO1 bioactivatable drugs as novel therapeutics for pancreatic cancer (2022-08-04)
作者:Lei Dou:1.School of Pharmaceutical Sciences, Beijing Advanced Innovation Center for Structural Biology, and Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, PR China. ; Huiqin Liu:1.School of Pharmaceutical Sciences, Beijing Advanced Innovation Center for Structural Biology, and Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, PR China. ; Kaixin Wang:1.School of Pharmaceutical Sciences, Beijing Advanced Innovation Center for Structural Biology, and Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, PR China. ; Jing Liu:1.MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing 100084, PR China. ; Lei Liu:1.School of Pharmaceutical Sciences, Beijing Advanced Innovation Center for Structural Biology, and Key L
期刊:Albumin binding revitalizes NQO1 bioactivatable drugs as novel therapeutics for pancreatic cancer
DOI:10.1016/j.jconrel.2022.07.033
影响因子 :11.5
引用产品: MIA PaCa-2 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , SW 1990 细胞
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ZMAT1 acts as a tumor suppressor in pancreatic ductal adenocarcinoma by inducing SIRT3/p53 signaling pathway (2004-02-20)
作者:Zuyi Ma:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.Shantou University of Medical College, Shantou, 515000, China. ; Zhenchong Li:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.South China University of Technology School of Medicine, Guangzhou, 51000, China. ; Shujie Wang:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China. ; Zixuan Zhou:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.South China University of Technology School of Medicine, Guangzhou, 51000, China. ; Chunsheng Liu:1.Department of General Surgery, Guangd
期刊:ZMAT1 acts as a tumor suppressor in pancreatic ductal adenocarcinoma by inducing SIRT3/p53 signaling pathway
DOI:10.1186/s13046-022-02310-8
影响因子 :11.3
引用产品: PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞 , SW 1990 细胞 , AsPC-1 细胞
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Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer (2022-12-10)
作者:Xiao-Yan Yang:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Jin-Guo Zhang:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Qiao-Mei Zhou:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Jie-Ni Yu:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Yuan-Fei Lu:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Xiao-Jie Wang:1.Department of Radiology, Second Affiliated Hospital, School
期刊:Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer
DOI:10.1186/s12951-022-01738-6
影响因子 :9.4
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Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2 (2022-09-20)
作者:Meijie Chen:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Xuena Li:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Bulin Du:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Song Chen:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Yaming Li:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ;
期刊:Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2
影响因子 :6.1
引用产品: PANC-1 细胞 , MIA PaCa-2 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , CFPAC-1 细胞 , SW 1990 细胞 , CFPAC-1细胞专用培养基 , SW 1990细胞专用培养基 (L15)
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Pyroptosis regulators exert crucial functions in prognosis, progression and immune microenvironment of pancreatic adenocarcinoma: a bioinformatic and in vitro research (2001-02-20)
作者:Zhenghai Bai:1.Department of Emergency, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Fangshi Xu:1.Department of Emergency, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; 2.Department of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Xiaodan Feng:1.Department of Emergency, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Yuan Wu:1.Department of Emergency, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Junhua Lv:1.Department of Emergency, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Yu Shi:1.Department of Emergency, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Honghong Pei:1.Department of Emergency, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaan
期刊:Pyroptosis regulators exert crucial functions in prognosis, progression and immune microenvironment of pancreatic adenocarcinoma: a bioinformatic and in vitro research
DOI:10.1080/21655979.2021.2019873
影响因子 :4.9
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GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma (2006-02-20)
作者:Xiaoyuan Sun:1.Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, 150081, China. ; Huijun Chu:1.Department of Gynecology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China. ; Ke Lei:1.Department of Gastroenterology, Center of Tumor Immunology and Cytotherapy, Medical Research Center, Affiliated Hospital of Qingdao University, Qingdao, 266003, China. ; Yandong Ci:1.Department of Orthopedics, Qingdao Eighth People's Hospital, Qingdao, 266003, China. ; Haijun Lu:1.Department of Radiation Oncology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China. ; Jia Wang:1.Department of Gastroenterology, Center of Tumor Immunology and Cytotherapy, Medical Research Center, Affiliated Hospital of Qingdao University, Qingdao, 266003, China. ; Meng Zhou:1.Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, 150081, China. ; He Ren:1.Department of Gastroenterology, Center o
期刊:GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma
影响因子 :4.0
引用产品: AsPC-1 细胞 , BxPC-3 细胞 , PANC-1 细胞 , MIA PaCa-2 细胞 , SW 1990 细胞
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IFN-γ affects pancreatic cancer properties by MACC1-AS1/MACC1 axis via AKT/mTOR signaling pathway (2001-02-20)
作者:X-Y Shi:1.Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China. ; X-L Zhang:1.Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China. ; Q-Y Shi:1.Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China. ; X Qiu:1.Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China. ; X-B Wu:1.Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China. ; B-L Zheng:1.Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China. ; H-X Jiang:1.Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nannin
期刊:IFN-γ affects pancreatic cancer properties by MACC1-AS1/MACC1 axis via AKT/mTOR signaling pathway
DOI:10.1007/s12094-021-02748-w
影响因子 :3.4
引用产品: BxPC-3 细胞
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SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis (2007-01-20)
作者:Dianyun Ren:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: rendianyun@hust.edu.cn. ; Yan Sun:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: yansun@hust.edu.cn. ; Dan Zhang:1.Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: whuh_zd@163.com. ; Dan Li:1.Cardiovascular Medicine Department, Union Hospital, Ton
期刊:SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis
DOI:10.1016/j.canlet.2021.07.035
影响因子 :9.7
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GSK2126458 has the potential to inhibit the proliferation of pancreatic cancer uncovered by bioinformatics analysis and pharmacological experiments (2008-01-20)
作者:Yueqin Feng:1.Department of Ultrasound, The First Affiliated Hospital of China Medical University, Shenyang, 110022, Liaoning, China. fengjinyueqin@163.com. ; Yuguan Jiang:1.School of Pharmacy, China Medical University, Shenyang, 110122, Liaoning, China. ; Fengjin Hao:1.Department of Biochemistry and Molecular Biology, China Medical University, Shenyang, 110122, Liaoning, China. ;
期刊:GSK2126458 has the potential to inhibit the proliferation of pancreatic cancer uncovered by bioinformatics analysis and pharmacological experiments
DOI:10.1186/s12967-021-03050-7
影响因子 :7.4
引用产品: BxPC-3 细胞
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CMTM3 Overexpression Predicts Poor Survival and Promotes Proliferation and Migration in Pancreatic Cancer (2008-01-20)
作者:Zixuan Zhou:1.South China University of Technology School of Medicine, Guangzhou 510006,Guangdong Province, China. ; 2.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; Zuyi Ma:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; 2.Shantou University of Medical College, Shantou 515000, China. ; Zhenchong Li:1.South China University of Technology School of Medicine, Guangzhou 510006,Guangdong Province, China. ; 2.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; Hongkai Zhuang:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; 2.Shantou University of Medical College, Shantou 515000, China. ; Chunsheng Liu:1.Department of General Surgery, Gua
期刊:CMTM3 Overexpression Predicts Poor Survival and Promotes Proliferation and Migration in Pancreatic Cancer
影响因子 :3.9
引用产品: SW 1990 细胞 , AsPC-1 细胞 , PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞
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Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway (2003-00-20)
作者:Xiangpeng Meng:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China. ; Jia Ma:1.Department of Gastrointestinal Endoscopy, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, People's Republic of China. ; Baosheng Wang:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China. ; Xin Wu:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China. ; Zhen Liu:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China. docliuz3@sina.com. ;
期刊:Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway
DOI:10.1007/s13105-020-00734-4
影响因子 :3.4
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