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产品概述
名称 | JIMT-1 (人乳腺癌细胞) (STR鉴定正确) |
别称 | JIMT1; JIMT |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样,单层生长 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:8 |
推荐换液频率 | 2-3次/周 |
背景描述 | established from the pleural effusion of a 62-year-old woman with ductal breast cancer (grade 3 invasive, T2N1M0) after postoperative radiation in 2003; cell line was described in the literature to carry an amplified HER-2 oncogene and to be insensitive to HER-2-inhibiting drugs, e.g. trastuzumab (Herceptin); listed in the CCLE (ref 18232) |
年龄(性别) | 女性;62岁 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 乳腺导管癌 |
生物安全等级 | BSL-1 |
倍增时间 | ~30-40 hours (DSMZ=ACC-589); 35.39 hours (GrayJW panel) |
保藏机构 | AddexBio; C0006005/50 DSMZ; ACC-589 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12,13 D2S1338 24 D3S1358 18 D5S818 12,13,14 D7S820 12 D8S1179 10,13 D13S317 8,13 D16S539 11 D18S51 10 D19S433 12,13 D21S11 27,31.2 FGA 21,23 PentaD 9,12 PentaE 7,19 TH01 7 TPOX 8 vWA 18 D6S1043 11 D12S391 17 D2S441 11.3,14 -
STR鉴定图
参考文献
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Characterization of a novel T cell-engaging bispecific antibody for elimination of L1CAM-positive tumors(2024/04/11)
作者:Yuan Yuan, Junyan Li, Jie Chen
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2024.116565
影响因子 :7.500
引用产品:CL-0770
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