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产品概述
| 名称 | MH-S (小鼠肺泡巨噬细胞) (种属鉴定正确) |
| 种属 | 小鼠 |
| 生长特性 | 半贴半悬 |
| 细胞形态 | 巨噬细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:5 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | The MH-S cell line was derived by SV40 transformation of an adherent cell enriched population of mouse alveolar macrophages. |
| 年龄（性别） | 雄性；7周龄 |
| 组织来源 | 肺巨噬细胞 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-2 |
| 抗原表达情况 | CD11b (Mac-1); Class II antigens (I-A); T antigen |
| 基因表达情况 | interleukin 1 (IL-1) |
| 保藏机构 | ATCC; CRL-2019 BCRC; 60419 ECACC; 95090612 |
STR鉴定
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STR位点信息
18-3 16 6-7 15 5-5 17 X-1 26,27 1-2 19 7-1 26.2 8-1 16 1-1 16 19-2 13 15-3 22.3 12-1 17 6-4 18 4-2 20.3 3-2 14 2-1 16 13-1 17.1,18.1
11-2 16 17-2 15 -
STR鉴定图
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参考文献
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Polyhexamethylene guanidine accelerates the macrophage foamy formation mediated pulmonary fibrosis (2024-02-13)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116084
影响因子 ：6.8
引用产品： MH-S 细胞 , NIH/3T3 细胞
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Discovery of the Active Compounds of the Ethyl Acetate Extract Site of Ardisia japonica (Thunb.) Blume for the Treatment of Acute Lung Injury (2024-02-07)
期刊：MOLECULES
影响因子 ：4.6
引用产品： MH-S 细胞
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Single-dose of hybrid eukaryotic-prokaryotic nanovesicles to drive a rapid and controllable immune response against Klebsiella pneumoniae induced nosocomial pneumonia (2023-12-28)
期刊：Nano Today
DOI：10.1016/j.nantod.2023.102135
影响因子 ：17.4
引用产品： MH-S 细胞
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Ythdf2 promotes pulmonary hypertension by suppressing Hmox1-dependent anti-inflammatory and antioxidant function in alveolar macrophages (2023-02-15)
期刊：Redox Biology
DOI：10.1016/j.redox.2023.102638
影响因子 ：11.4
引用产品： MH-S 细胞
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Naringin alleviates pneumonia caused by Klebsiella pneumoniae infection by suppressing NLRP3 inflammasome (2023-12-18)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.116028
影响因子 ：7.5
引用产品： MH-S 细胞
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Uncovering mechanisms of Baojin Chenfei formula treatment for silicosis by inhibiting inflammation and fibrosis based on serum pharmacochemistry and network analysis (2023-05-29)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115082
影响因子 ：6.8
引用产品： HFL1 细胞 , MH-S 细胞 , Ham's F-12K 培养基 , 青霉素-链霉素溶液 (双抗)，100×
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5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway (2023-07-17)
期刊：INFLAMMATION RESEARCH
DOI：10.1007/s00011-023-01769-1
影响因子 ：6.7
引用产品： MH-S 细胞
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MiR-223-3p attenuates radiation-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages (2023-07-16)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110616
影响因子 ：5.6
引用产品： MH-S 细胞
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Cordyceps militaris Solid Medium Extract Alleviates Lipoteichoic Acid-Induced MH-S Inflammation by Inhibiting TLR2/NF-κB/NLRP3 Pathways (2023-10-24)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.6
引用产品： MH-S 细胞
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4-octyl itaconate ameliorates alveolar macrophage pyroptosis against ARDS via rescuing mitochondrial dysfunction and suppressing the cGAS/STING pathway (2023-03-31)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110104
影响因子 ：5.6
引用产品： MH-S 细胞
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A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages (2023-09-21)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110965
影响因子 ：5.6
引用产品： MH-S 细胞
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Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD (2023-12-02)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： MH-S 细胞
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Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary alveolar macrophage pyroptosis (2023-10-28)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： MH-S 细胞
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Xuanfei Baidu Decoction suppresses complement overactivation and ameliorates IgG immune complex-induced acute lung injury by inhibiting JAK2/STAT3/SOCS3 and NF-κB signaling pathway (2022-11-21)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2022.154551
影响因子 ：6.7
引用产品： MH-S 细胞
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Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS-induced inflammation in vitro and in vivo (2022-09-23)
期刊：Food Science & Nutrition
影响因子 ：3.6
引用产品： MH-S 细胞
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Effective-components combination improves airway remodeling in COPD rats by suppressing M2 macrophage polarization via the inhibition of mTORC2 activity (2009-01-20)
期刊：Phytomedicine
DOI：10.1016/j.phymed.2021.153759
影响因子 ：7.9
引用产品： MH-S 细胞
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Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection (2003-01-20)
期刊：Frontiers in Cellular and Infection Microbiology
影响因子 ：5.5
引用产品： MH-S 细胞 , RAW 264.7 细胞
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Transforming Growth Factor-β1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis (2008-01-20)
期刊：Frontiers in Cellular and Infection Microbiology
影响因子 ：5.5
引用产品： MH-S 细胞
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MicroRNA-205-5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2-mediated Beclin1 ubiquitination (2008-01-20)
期刊：Journal Of Cellular And Molecular Medicine
影响因子 ：5.3
引用产品： MH-S 细胞 , 293T [HEK-293T] 细胞
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Upregulated expression of long non-coding RNA MEG3 serves as a prognostic biomarker in severe pneumonia children and its regulatory mechanism (2009-01-20)
期刊：Bioengineered
DOI：10.1080/21655979.2021.1979351
影响因子 ：4.9
引用产品： MH-S 细胞
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3-O-trans-caffeoyloleanolic acid improves acute lung injury via anti-inflammation and antioxidative stress-involved PI3K/AKT pathway (2005-01-20)
期刊：Chemical Biology & Drug Design
影响因子 ：2.9
引用产品： MH-S 细胞
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LncRNA NEAT1 Knockdown Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulation of miR-182-5p/WISP1 Axis (2005-01-20)
期刊：Biochemical Genetics
DOI：10.1007/s10528-021-10081-8
影响因子 ：2.4
引用产品： MH-S 细胞 , RPMI-1640完全培养基 (含10%FBS)
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