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产品概述
名称 | Neuro-2a [N2a; Neuro-2a] (小鼠脑神经瘤细胞) (STR鉴定正确) |
别称 | NEURO-2A; Neuro 2a; Neuro2a; Neuro2A; N-2a; N2a; N2A; Nb2a; NB2a |
种属 | 小鼠 |
生长特性 | 贴壁细胞 |
细胞形态 | 神经细胞样、阿米巴样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | Neuro-2a [N2a; Neuro-2a]细胞是由R·J·Klebe和F·H·Ruddle经A株白鼠的自生肿瘤建立;Neuro-2a [N2a; Neuro-2a]细胞产生大量微管蛋白,此蛋白在神经细胞中起应答轴浆流动的收缩系统作用。 |
组织来源 | 脑神经母细胞瘤,神经母细胞 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 神经母细胞瘤细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~70 hours |
抗原表达情况 | H-2, a haploType; Mus musculus, expressed |
基因表达情况 | acetylcholinesterase, tubulin |
保藏机构 | ATCC; CCL-131 DSMZ; ACC-148 ECACC; 89121404 |
STR鉴定
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STR位点信息
18-3 22 6-7 12 5-5 15,17 X-1 26,27 1-2 17,18 7-1 25.2 8-1 16,17 1-1 11 19-2 12 15-3 21.3,22.3,23.3,24.3 12-1 16 6-4 18,20 4-2 21.3,22.3 3-2 13,14 2-1 16 13-1 16.2,17.2
11-2 15 17-2 16 -
STR鉴定图
参考文献
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Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders(2024/01/22)
作者:Ailian Wang, Chen Chen, Chen Mei
期刊:NATURE CELL BIOLOGY
DOI:10.1038/s41556-023-01339-x
影响因子 :21.300
引用产品:CL-0168
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A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease(2024/01/24)
作者:Jiefei Wang, Shangguan Ping, Xiaoyu Chen
期刊:Nature Communications
DOI:10.1038/s41467-024-44737-x
影响因子 :16.600
引用产品:CL-0168
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SSK1-Loaded Neurotransmitter-Derived Nanoparticles for Alzheimers Disease Therapy via Clearance of Senescent Cells(2024/03/01)
作者:Wenbo Ji, Honglei Zhou, Wendanqi Liang
期刊:Small
影响因子 :13.300
引用产品:CL-0168
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CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinsons disease(2022/08/12)
作者:Quancheng Cheng, Jianwei Wang, Man Li
期刊:Redox Biology
DOI:10.1016/j.redox.2022.102430
影响因子 :11.400
引用产品:CL-0168
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Anti-ferroptosis exosomes engineered for targeting M2 microglia to improve neurological function in ischemic stroke(2024/05/27)
作者:Yong Wang, Zhuohang Liu, Luyu Li
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-024-02560-y
影响因子 :10.200
引用产品:CL-0168
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Anti-CHAC1 exosomes for nose-to-brain delivery of miR-760-3p in cerebral ischemia/reperfusion injury mice inhibiting neuron ferroptosis(2023/03/27)
作者:Yong Wang, Huicong Niu, Luyu Li
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-023-01862-x
影响因子 :10.200
引用产品:CL-0168
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Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging(2022/10/01)
作者:Minghao Yuan, Yangyang Wang, Jie Wen
期刊:Aging and Disease
影响因子 :9.968
引用产品:CL-0168
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Olfactory bulb microglia activation mediated neuronal death in real-ambient particulate matter exposure mice with depression-like behaviors(2022/01/29)
作者:Xiaoya Ji, Rui Liu, Jiajun Guo
期刊:Science Of The Total Environment
DOI:10.1016/j.scitotenv.2022.153456
影响因子 :9.800
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Piceatannol-3′-O-β-D-glucopyranoside attenuates colistin-induced neurotoxicity by suppressing oxidative stress via the NRF2/HO-1 pathway(2023/02/21)
作者:Liguang Xiong, Debiao Xiang, Fang Yuan
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2023.114419
影响因子 :7.500
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Identification and analysis of short open reading frame-encoded peptides in different regions of mouse brain(2023/03/17)
作者:Shengjie Li, Die Peng, Ni Pan
期刊:iScience
DOI:10.1016/j.isci.2023.106427
影响因子 :5.800
引用产品:CL-0168
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YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring(2023/12/09)
作者:Likui Lu, Yajun Shi, Bin Wei
期刊:iScience
DOI:10.1016/j.isci.2023.108703
影响因子 :5.800
引用产品:CL-0168
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Berberine Rescues D-Ribose-Induced Alzheimer‘s Pathology via Promoting Mitophagy(2023/03/20)
作者:Chuanling Wang, Qian Zou, Yinshuang Pu
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.600
引用产品:CL-0168
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Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation(2024/04/13)
作者:Jiaxi Chen, Jieping Zhang, Lijuan Cai
期刊:Marine Drugs
影响因子 :5.400
引用产品:CL-0168
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Extracellular cold-inducible RNA-binding protein mediated neuroinflammation and neuronal apoptosis after traumatic brain injury(2024/05/29)
作者:Yuxiao Liu, Ming Zhao, Yang Yu
期刊:Burns & Trauma
影响因子 :5.300
引用产品:CL-0168
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High-fat diet induces cognitive impairment through repression of SIRT1/AMPK-mediated autophagy(2023/10/26)
作者:Wenmin Yi, Fei Chen, Minghao Yuan
期刊:EXPERIMENTAL NEUROLOGY
DOI:10.1016/j.expneurol.2023.114591
影响因子 :5.300
引用产品:CL-0168
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Enriched oxygen improves age-related cognitive impairment through enhancing autophagy(2024/02/14)
作者:Shengyuan Wang, Bengang Chen, Minghao Yuan
期刊:Frontiers in Aging Neuroscience
DOI:10.3389/fnagi.2024.1340117
影响因子 :4.800
引用产品:CL-0168
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Network Pharmacology and Molecular Docking Identify the Potential Mechanism and Therapeutic Role of Scutellaria baicalensis in Alzheimer’s Disease(2024/04/18)
作者:Yutao Peng, Chanjuan Zhou
期刊:Drug Design Development and Therapy
影响因子 :4.800
引用产品:CL-0168
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Dietary salt promotes cognition impairment through GLP-1R/mTOR/p70S6K signaling pathway(2024/04/04)
作者:Xu Yang, Shu Liu, Chuanling Wang
期刊:Scientific Reports
DOI:10.1038/s41598-024-57998-9
影响因子 :4.600
引用产品:CL-0168
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Biological and Immunological Characterization of a Functional L-HN Derivative of Botulinum Neurotoxin Serotype F(2023/03/06)
作者:Zhiying Li, Bolin Li, Jiansheng Lu
期刊:Toxins
影响因子 :4.200
引用产品:CL-0168
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Molecular mechanism of Acanthopanax senticosus in the treatment of Alzheimer’s disease based on network pharmacology and molecular docking(2022/12/28)
作者:Kuang Feng, Xiang Tao
期刊:MOLECULAR DIVERSITY
DOI:10.1007/s11030-022-10586-3
影响因子 :3.800
引用产品:CL-0168
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Neuroprotective effects of miR-532-5p against ischemic stroke(2020/01/21)
作者:Jingwei Mu, Xi Cheng, Shanshan Zhong
期刊:Metabolic Brain Disease
DOI:10.1007/s11011-020-00544-z
影响因子 :3.600
引用产品:CL-0168
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High salt diet induces cognitive impairment and is linked to the activation of IGF1R/mTOR/p70S6K signaling(2024/05/21)
作者:Shu Liu, Xu Yang, Minghao Yuan
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-024-01358-z
影响因子 :3.600
引用产品:CL-0168
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LncRNA SNHG3 promotes autophagy-induced neuronal cell apoptosis by acting as a ceRNA for miR-485 to up-regulate ATG7 expression( 2020/8/29)
作者:Yanbin Cao, Lihua Pan, Xuejun Zhang
期刊:Metabolic Brain Disease
DOI:10.1007/s11011-020-00607-1
影响因子 :3.600
引用产品:CL-0168
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miR‑183‑5p attenuates cerebral ischemia injury by negatively regulating PTEN(2020/9/7)
作者:Li Zhu, Xueying Zhou, Shanshan Li
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0168
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Downregulation of BACH1 Protects AGAINST Cerebral Ischemia/Reperfusion Injury through the Functions of HO-1 and NQO1(2020/6/1)
作者:Shan Yu, Jingjie Zhai, Jing Yu
期刊:Neuroscience
DOI:10.1016/j.neuroscience.2020.04.014.
影响因子 :3.300
引用产品:CL-0168
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Activation of β2-adrenergic receptor ameliorates amyloid-β-induced mitophagy defects and tau pathology in mice(2022/10/05)
作者:Gaoshang Chai, Jiajun Wu, Juan Gong
期刊:NEUROSCIENCE
DOI:10.1016/j.neuroscience.2022.09.020
影响因子 :3.300
引用产品:CL-0168
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Biology activity and characterization of the functional L-HN fragment derivative of botulinum neurotoxin serotype E(2023/07/20)
作者:Xiao Tan, Congcong Zhang, Jiansheng Lu
期刊:ANAEROBE
DOI:10.1016/j.anaerobe.2023.102764
影响因子 :2.300
引用产品:CL-0168
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Effect of intrathecal injection of γ-Oryzanol on motor function in mice after spinal cord injury(2023/09/18)
作者:Zhiyi Fan, Wanda Zhan, Jun Cai
期刊:Interdisciplinary Neurosurgery-Advanced Techniques and Case Management
DOI:10.1016/j.inat.2023.101845
影响因子 :0.400
引用产品:CL-0168
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Dietary High-Fat Promotes Cognitive Impairment by Suppressing Mitophagy(2023/01/21)
作者:Jie Wen, Yangyang Wang, Chuanling Wang
期刊:Oxidative Medicine and Cellular Longevity
影响因子 :0.000
引用产品:CL-0168
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