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产品概述
| 名称 | Capan-2 (人胰腺癌细胞) (STR鉴定正确) |
| 种属 | 人类 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | Capan-2是一种多角形细胞系，1975年从一名56岁白人男性胰腺癌患者的胰腺中分离出来。 |
| 年龄（性别） | 男性；56岁 |
| 组织来源 | 胰腺 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胰腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | 96 hours (PubMed=3019537); 45-60 hours (CLS); ~50-70 hours (DSMZ). |
| 致瘤性 | Yes, in nude mice; forms well differentiated adenocarcinoma consistent with pancreatic carcinoma |
| 抗原表达情况 | Blood Type B; Rh+ |
| 基因表达情况 | Blood Type B; Rh+; high levels of MUC-1 mucin mRNA; low levels of MUC-2 mRNA; MUC-3 gene not expressed |
| 保藏机构 | ATCC; HTB-80BCRJ; 0060CLS; 300144/p660_Capan-2DSMZ; ACC-245IZSLER; BS TCL 10KCLB; 30080 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 19,25 D3S1358 17,18 D5S818 11,12 D7S820 9,11 D8S1179 12,13 D13S317 11,12 D16S539 9,13 D18S51 13 D19S433 13,15 D21S11 31 FGA 21,24 PentaD 13,15 PentaE 11 TH01 9.3 TPOX 8 vWA 17 D6S1043 11 D12S391 20,23 D2S441 8,10 -
STR鉴定图
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参考文献
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LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4 (2024-03-19)
作者：Zhenchong Li:1.Department of General Surgery, Heyuan people's Hospital, Heyuan, 517000, China. ; 2.Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. ; 3.Junior Clinical Cooperation Unit Translational Gastrointestinal Oncology and Preclinical Models, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. ; Zuyi Ma:1.Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China. ; Shujie Wang:1.The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong Province, 510515, China. ; Qian Yan:1.Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. ; 2.South China Univer
期刊：LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4
DOI：10.1186/s13062-024-00463-4
影响因子 ：5.5
引用产品： PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞 , AsPC-1 细胞 , SW 1990 细胞 , HPED-6 细胞
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5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis (2023-10-12)
作者：Wenpeng Cao:1.Department of Anatomy, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Zhirui Zeng:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Shan Lei:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ;
期刊：5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis
影响因子 ：5.5
引用产品： MIA PaCa-2 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , Capan-2 细胞 , SW 1990 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , 人胰腺上皮细胞
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ZMAT1 acts as a tumor suppressor in pancreatic ductal adenocarcinoma by inducing SIRT3/p53 signaling pathway (2004-02-20)
作者：Zuyi Ma:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.Shantou University of Medical College, Shantou, 515000, China. ; Zhenchong Li:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.South China University of Technology School of Medicine, Guangzhou, 51000, China. ; Shujie Wang:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China. ; Zixuan Zhou:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. ; 2.South China University of Technology School of Medicine, Guangzhou, 51000, China. ; Chunsheng Liu:1.Department of General Surgery, Guangd
期刊：ZMAT1 acts as a tumor suppressor in pancreatic ductal adenocarcinoma by inducing SIRT3/p53 signaling pathway
DOI：10.1186/s13046-022-02310-8
影响因子 ：11.3
引用产品： PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞 , SW 1990 细胞 , AsPC-1 细胞
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Deciphering the action mechanism of paeoniflorin in suppressing pancreatic cancer: A network pharmacology study and experimental validation (2022-10-20)
作者：Chunhao Cao:1.Department of Integrated Traditional Chinese and Western Medicine, The First Affiliate Hospital of Chongqing Medical University, Chongqing, China. ; Wenting Zhao:1.Hubei University of Chinese Medicine, Wuhan, China. ; Xianglin Chen:1.Hubei University of Chinese Medicine, Wuhan, China. ; Bin Shen:1.Chongqing Medical University, Chongqing, China. ; Teng Wang:1.Chongqing Medical University, Chongqing, China. ; Chaoxu Wu:1.Department of Integrated Traditional Chinese and Western Medicine, The First Affiliate Hospital of Chongqing Medical University, Chongqing, China. ; Xiaofeng Rong:1.Department of Integrated Traditional Chinese and Western Medicine, The First Affiliate Hospital of Chongqing Medical University, Chongqing, China. ;
期刊：Deciphering the action mechanism of paeoniflorin in suppressing pancreatic cancer: A network pharmacology study and experimental validation
DOI：10.3389/fphar.2022.1032282
影响因子 ：6.0
引用产品： PANC-1 细胞 , Capan-2 细胞
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CMTM3 Overexpression Predicts Poor Survival and Promotes Proliferation and Migration in Pancreatic Cancer (2008-01-20)
作者：Zixuan Zhou:1.South China University of Technology School of Medicine, Guangzhou 510006,Guangdong Province, China. ; 2.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; Zuyi Ma:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; 2.Shantou University of Medical College, Shantou 515000, China. ; Zhenchong Li:1.South China University of Technology School of Medicine, Guangzhou 510006,Guangdong Province, China. ; 2.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; Hongkai Zhuang:1.Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ; 2.Shantou University of Medical College, Shantou 515000, China. ; Chunsheng Liu:1.Department of General Surgery, Gua
期刊：CMTM3 Overexpression Predicts Poor Survival and Promotes Proliferation and Migration in Pancreatic Cancer
影响因子 ：3.9
引用产品： SW 1990 细胞 , AsPC-1 细胞 , PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞
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