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产品概述
| 名称 | CFPAC-1 (人胰腺癌细胞) (STR鉴定正确) |
| 别称 | CFPac-1; CF PAC-1; CF-PAC1; CF-Pac1; CF Pac1; CFPAC1; CFPac1; CFPAC |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | CFPAC-1细胞是胰腺管腺癌细胞系，建自26岁白人男性囊性纤维变性(CF)的肝转移灶。CFPAC-1细胞表达囊性纤维变性跨膜调节因子(CFTR)，CFPAC-1细胞形态为上皮细胞样且顶端微绒毛极化。CFPAC-1细胞表达胰腺管细胞特征性的细胞角蛋白和癌胚抗原，倍增时间为30-32小时。CFPAC-1细胞是亚3倍体的细胞系，36％的细胞的染色体模式数为75。CFPAC-1细胞传代至24代时，可在免疫抑制小鼠中致瘤。 |
| 年龄（性别） | 男性；26岁 |
| 组织来源 | 胰腺管腺癌，肝转移 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胰腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~30-45 hours |
| 致瘤性 | Yes, in nude mice (passage 34) |
| 抗原表达情况 | CA19-9 antigen, 12000 units/mL, epithelial keratins |
| 基因表达情况 | carcinoembryonic antigen (CEA), 9ng/mL; pancreatic oncofetal antigen (POA), 28ng/mL; adenocarcinoma associated antigen (ACAA), 5000ng/mL; CA 19-9 antigen, 12000 units/mL; epithelial keratins |
| 保藏机构 | ATCC; CRL-1918 ECACC; 91112501 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10 D2S1338 18,23 D3S1358 16 D5S818 10,11 D7S820 8,10 D8S1179 11,15 D13S317 12 D16S539 9,11 D18S51 12 D19S433 13,15 D21S11 30,31.2 FGA 21,22 PentaD 11,13 PentaE 10,12 TH01 8 TPOX 8 vWA 17 D6S1043 20 D12S391 17 D2S441 10,14 -
STR鉴定图
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参考文献
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Concurrent inhibition of pBADS99 synergistically improves MEK inhibitor efficacy in KRASG12D-mutant pancreatic ductal adenocarcinoma (2024-02-26)
作者：Yan Qin Tan:1.Institute of Biopharmaceutical and Health Engineering and Tsinghua Berkeley Shenzhen Institute, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, People's Republic of China. ; 2.Food Science and Technology Program, Department of Life Sciences, BNU-HKBU United International College, Zhuhai, 519087, Guangdong, People's Republic of China. ; Bowen Sun:1.Institute of Biopharmaceutical and Health Engineering and Tsinghua Berkeley Shenzhen Institute, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, People's Republic of China. ; Xi Zhang:1.Institute of Biopharmaceutical and Health Engineering and Tsinghua Berkeley Shenzhen Institute, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, People's Republic of China. ; 2.Shenzhen Bay Laboratory, Shenzhen, 518055, Guangdong, People's Republic of China. ; Shuwei Zhang:1.Institute of Biopharmaceutical and Health Engineering
期刊：Concurrent inhibition of pBADS99 synergistically improves MEK inhibitor efficacy in KRASG12D-mutant pancreatic ductal adenocarcinoma
DOI：10.1038/s41419-024-06551-7
影响因子 ：9.0
引用产品： SW 1990 细胞 , PANC-1 细胞 , AsPC-1 细胞 , CFPAC-1 细胞
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METTL3 promotes pancreatic cancer proliferation and stemness by increasing stability of ID2 mRNA in a m6A-dependent manner (2023-05-19)
作者：Jiaoshun Chen:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; Haoxiang Zhang:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; Chaoyang Xiu:1.TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610000, China. ; Chenggang Gao:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wu
期刊：METTL3 promotes pancreatic cancer proliferation and stemness by increasing stability of ID2 mRNA in a m6A-dependent manner
DOI：10.1016/j.canlet.2023.216222
影响因子 ：9.7
引用产品： PC 细胞 , CFPAC-1 细胞 , HPDEC 细胞 , Panc02 细胞
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High glucose-upregulated PD-L1 expression through RAS signaling-driven downregulation of PTRH1 leads to suppression of T cell cytotoxic function in tumor environment (2023-07-11)
作者：Chenggang Gao:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; 2.Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; Jiaoshun Chen:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; 2.Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; Jianwei Bai:1.Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; 2.Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer, Union Hospital, Tongji Medical College, Huazhong University of Science and T
期刊：High glucose-upregulated PD-L1 expression through RAS signaling-driven downregulation of PTRH1 leads to suppression of T cell cytotoxic function in tumor environment
DOI：10.1186/s12967-023-04302-4
影响因子 ：7.4
引用产品： CFPAC-1 细胞 , Panc02 细胞
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Construction and comprehensive analysis of a novel prognostic signature associated with pyroptosis molecular subtypes in patients with pancreatic adenocarcinoma (2023-02-03)
作者：Qian Huang:1.Department of General Practice, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. ; 2.Department of Geriatrics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. ; Xingyu Peng:1.Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China. ; Qingqing Li:1.Department of General Practice, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. ; 2.Department of Geriatrics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. ; Jinfeng Zhu:1.Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China. ; Ju Xue:1.Department of Pathology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China. ; Hua Jiang:1.Department of General Practice, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. ; 2.Department o
期刊：Construction and comprehensive analysis of a novel prognostic signature associated with pyroptosis molecular subtypes in patients with pancreatic adenocarcinoma
DOI：10.3389/fimmu.2023.1111494
影响因子 ：7.3
引用产品： CFPAC-1 细胞 , CFPAC-1细胞专用培养基
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Crosstalk of ferroptosis regulators and tumor immunity in pancreatic adenocarcinoma: novel perspective to mRNA vaccines and personalized immunotherapy (2023-06-27)
作者：Yanlong Shi:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Yizhu Wang:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Hui Dong:1.School of Medicine, Southeast University, 210009, Nanjing, China. ; Kaiyi Niu:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Wenning Zhang:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Kun Feng:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Rui Yang:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, 210003, Nanjing, Jiangsu Province, China. ; Yewei Zhang:1.H
期刊：Crosstalk of ferroptosis regulators and tumor immunity in pancreatic adenocarcinoma: novel perspective to mRNA vaccines and personalized immunotherapy
DOI：10.1007/s10495-023-01868-8
影响因子 ：7.2
引用产品： HPNE 细胞 , CFPAC-1 细胞 , SW 1990 细胞 , BxPC-3 细胞
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PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression (2023-04-10)
作者：Jia Ma:1.Department of Gastroenterology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Wenyang Zhou:1.Department of Pathology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Yifeng Yuan:1.Pancreatic Endocrinology Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Baosheng Wang:1.Pancreatic Endocrinology Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Xiangpeng Meng:1.Pancreatic Endocrinology Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. mengxp@sj-hospital.org. ;
期刊：PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression
DOI：10.1038/s41417-023-00609-y
影响因子 ：6.4
引用产品： CFPAC-1 细胞 , IMDM 培养基 , Leibovitz's L-15 培养基
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5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis (2023-10-12)
作者：Wenpeng Cao:1.Department of Anatomy, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Zhirui Zeng:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Shan Lei:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ;
期刊：5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis
影响因子 ：5.5
引用产品： MIA PaCa-2 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , Capan-2 细胞 , SW 1990 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , 人胰腺上皮细胞
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RBM15 Promates the Proliferation, Migration and Invasion of Pancreatic Cancer Cell Lines (2023-02-08)
作者：Hui Dong:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Haidong Zhang:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Xinyu Mao:1.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China. ; Shiwei Liu:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Wenjing Xu:1.School of Medicine, Southeast University, Nanjing 210009, China. ; Yewei Zhang:1.School of Medicine, Southeast University, Nanjing 210009, China. ; 2.Hepatopancreatobiliary Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China. ;
期刊：RBM15 Promates the Proliferation, Migration and Invasion of Pancreatic Cancer Cell Lines
影响因子 ：5.2
引用产品： HPNE 细胞 , CFPAC-1 细胞 , BxPC-3 细胞
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COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation (2023-02-26)
作者：Yao Song:1.Department of Radiotherapy and Oncology, Affiliated Hospital of Nantong University, Nantong 226001, China. ; 2.Department of Radiation Oncology, Tenth People's Hospital Afflfliated to Tongji University, Shanghai 200072, China. ; Lei Wang:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; Kaidong Wang:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; Yuhua Lu:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; Pengcheng Zhou:1.Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China. ; 2.Department of Surgery, Medical School, Southeast University, Nanjing 210009, China. ;
期刊：COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation
影响因子 ：5.2
引用产品： PANC-1 细胞 , BxPC-3 细胞 , CFPAC-1 细胞 , PATU8988 细胞 , AsPC-1 细胞 , MIA PaCa-2 细胞
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Identifying endoplasmic reticulum stress-related molecular subtypes and prognostic model for predicting the immune landscape and therapy response in pancreatic cancer (2023-10-09)
作者：Biao Zhang:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; Xu Chen:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; Zhizhou Wang:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; Fangyue Guo:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; 2.Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China. ; Xiaonan Zhang:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; 2.Institute (College) of Integrative Medicine, Dalian Medical University
期刊：Identifying endoplasmic reticulum stress-related molecular subtypes and prognostic model for predicting the immune landscape and therapy response in pancreatic cancer
影响因子 ：5.2
引用产品： CFPAC-1 细胞 , PANC-1 细胞
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GID2 Interacts With CDKN3 and Regulates Pancreatic Cancer Growth and Apoptosis (2023-02-23)
作者：Xin Deng:1.Pancreatic Endocrinology Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Jia Ma:1.Department of Gastroenterology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Wenyang Zhou:1.Department of Pathology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Yifeng Yuan:1.Pancreatic Endocrinology Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Baosheng Wang:1.Pancreatic Endocrinology Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ; Xiangpeng Meng:1.Pancreatic Endocrinology Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. Electronic address: mengxp@sj-hospital.org. ;
期刊：GID2 Interacts With CDKN3 and Regulates Pancreatic Cancer Growth and Apoptosis
DOI：10.1016/j.labinv.2023.100122
影响因子 ：5.0
引用产品： CFPAC-1 细胞 , IMDM 培养基 , Leibovitz's L-15 培养基
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Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer (2023-05-12)
作者：Junliang Chen:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. ; Zhihao Liu:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. ; Zhiyuan Wu:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. ; Wenjun Li:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. ; Xiaodong Tan:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. ;
期刊：Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer
影响因子 ：4.7
引用产品： AsPC-1 细胞 , CFPAC-1 细胞 , PANC-1 细胞 , IMDM 培养基 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100×
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PANoptosis-related molecular subtype and prognostic model associated with the immune microenvironment and individualized therapy in pancreatic cancer (2023-07-14)
作者：Biao Zhang:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; Bingqian Huang:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; 2.Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China. ; Xiaonan Zhang:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; 2.Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China. ; Shuang Li:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China. ; Jingyi Zhu:1.Department of General Surgery, Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical Univers
期刊：PANoptosis-related molecular subtype and prognostic model associated with the immune microenvironment and individualized therapy in pancreatic cancer
影响因子 ：4.7
引用产品： PANC-1 细胞 , CFPAC-1 细胞
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Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer (2023-10-24)
作者：Xu Chen:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; 2.Laboratory of Integrative Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Qihang Yuan:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Hewen Guan:1.Department of Dermatology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Xueying Shi:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; 2.Laboratory of Integrative Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Jiaao Sun:1.Department of Urology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Zhiqiang Wu:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ;
期刊：Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer
影响因子 ：4.7
引用产品： BxPC-3 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , MIA PaCa-2 细胞
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Involvement of Ataxin-3 (ATXN3) in the malignant progression of pancreatic cancer via deubiquitinating HDAC6 (2023-07-07)
作者：Xin Wu:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, PR China. ; Xin Zhang:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, PR China. ; Peng Liu:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, PR China. ; Yao Wang:1.Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, PR China. Electronic address: wangyao@sj-hospital.org. ;
期刊：Involvement of Ataxin-3 (ATXN3) in the malignant progression of pancreatic cancer via deubiquitinating HDAC6
影响因子 ：3.6
引用产品： CFPAC-1 细胞
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A prospective prognostic signature for pancreatic adenocarcinoma based on ubiquitination-related mRNA-lncRNA with experimental validation in vitro and vivo (2023-08-04)
作者：Zhizhou Wang:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; 2.Laboratory of Integrative Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Qihang Yuan:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Xu Chen:1.Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; Fei Luo:1.Laboratory of Integrative Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; 2.Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, China. ; Xueying Shi:1.Laboratory of Integrative Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. ; 2.Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, China. ; Fangyue Guo:1.Laboratory of I
期刊：A prospective prognostic signature for pancreatic adenocarcinoma based on ubiquitination-related mRNA-lncRNA with experimental validation in vitro and vivo
DOI：10.1007/s10142-023-01158-1
影响因子 ：2.9
引用产品： CFPAC-1 细胞 , PANC-1 细胞 , IMEM
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System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma (2022-10-05)
作者：Cheng Yan:1.School of Pharmacy, Key Laboratory of Nano-Carbon Modified Film Technology of Henan Province, Diagnostic Laboratory of Animal Diseases, Xinxiang University, Xinxiang, 453000, Henan, China. ; Yandie Niu:1.School of Pharmacy, Key Laboratory of Nano-Carbon Modified Film Technology of Henan Province, Diagnostic Laboratory of Animal Diseases, Xinxiang University, Xinxiang, 453000, Henan, China. ; Feng Li:1.School of Pharmacy, Key Laboratory of Nano-Carbon Modified Film Technology of Henan Province, Diagnostic Laboratory of Animal Diseases, Xinxiang University, Xinxiang, 453000, Henan, China. ; Wei Zhao:1.School of Pharmacy, Key Laboratory of Nano-Carbon Modified Film Technology of Henan Province, Diagnostic Laboratory of Animal Diseases, Xinxiang University, Xinxiang, 453000, Henan, China. ; Liukai Ma:1.School of Pharmacy, Key Laboratory of Nano-Carbon Modified Film Technology of Henan Province, Diagnostic Laboratory of Animal Diseases, Xinxiang University, Xinxiang, 453000,
期刊：System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma
DOI：10.1186/s12967-022-03632-z
影响因子 ：8.4
引用产品： CFPAC-1 细胞 , PANC-1 细胞
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Synthesis and anti-tumor activity of nitrogen-containing derivatives of the natural product diphyllin (2022-08-26)
作者：Yang Li:1.Targeted Drug Research Center of Digestive Tract Tumor, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China. ; Qing Lu:1.Targeted Drug Research Center of Digestive Tract Tumor, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China. ; Ruoxuan Xiao:1.Targeted Drug Research Center of Digestive Tract Tumor, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China. ; Jing Ma:1.Targeted Drug Research Center of Digestive Tract Tumor, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China. ; Yuqi Tang:1.Targeted Drug Research Center of Digestive Tract Tumor, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China; Department of Oral and Maxillofacial-Head & Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China. ; Wantao Che
期刊：Synthesis and anti-tumor activity of nitrogen-containing derivatives of the natural product diphyllin
DOI：10.1016/j.ejmech.2022.114708
影响因子 ：7.1
引用产品： MIA PaCa-2 细胞 , CFPAC-1 细胞 , PaTu 8988t 细胞
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Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2 (2022-09-20)
作者：Meijie Chen:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Xuena Li:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Bulin Du:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Song Chen:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ; Yaming Li:1.Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang, China. ;
期刊：Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2
影响因子 ：6.1
引用产品： PANC-1 细胞 , MIA PaCa-2 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , CFPAC-1 细胞 , SW 1990 细胞 , CFPAC-1细胞专用培养基 , SW 1990细胞专用培养基 (L15)
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miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression (2005-09-20)
作者：Wenjie Huang:1.Department of First Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University Guangzhou 510280, Guangdong, China. ; 2.Institute of Hepatopancreatobiliary Surgery, Southwest Hospital, Army Medical University Chongqing 400038, China. ; Yaohuan Huang:1.Department of First Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University Guangzhou 510280, Guangdong, China. ; Jianyou Gu:1.Department of First Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University Guangzhou 510280, Guangdong, China. ; Junfeng Zhang:1.Institute of Hepatopancreatobiliary Surgery, Southwest Hospital, Army Medical University Chongqing 400038, China. ; Jiali Yang:1.Institute of Hepatopancreatobiliary Surgery, Southwest Hospital, Army Medical University Chongqing 400038, China. ; Songsong Liu:1.Institute of Hepatopancreatobiliary Surgery, Southwest Hospital, Army Medical University Chongqing 400038, China. ; Chuanming Xie:1.Institute of Hepatopancreatobiliary Surg
期刊：miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression
DOI：PMID:31217868
影响因子 ：2.2
引用产品： AsPC-1 细胞 , CFPAC-1 细胞
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