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产品概述
名称 | HBE135-E6E7 (人支气管上皮细胞) (STR鉴定正确) |
别称 | HBE 135-E6E7; HBE 135-E6/E7 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样;卵圆形 |
冻存条件 | 冻存液:55%DM/F12+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | The HBE135-E6E7 cell line was derived from normal bronchial epithelium taken from a man undergoing lobectomy for squamous cell carcinoma. Cells from the primary explant in their first passage were infected with the recombinant retrovirus LXSN16E6E7 containing the human papilloma virus (HPV) E6E7 gene. Cells were selected in the presence of 0.4 mg/mL G418 |
年龄(性别) | 男性,;54岁 |
组织来源 | 肺;支气管 |
细胞类型 | 转化细胞系 |
生物安全等级 | BSL-2 |
倍增时间 | 24-30 hours |
保藏机构 | ATCC; CRL-2741 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 9,11 D2S1338 16,17 D3S1358 15,17 D5S818 12 D7S820 9,10 D8S1179 13,14 D13S317 8,11 D16S539 9,12 D18S51 12 D19S433 13,16 D21S11 28,30 FGA 24,25 PentaD 9,12 PentaE 12,16 TH01 5,6 TPOX 8,10 vWA 16,17 D6S1043 13 D12S391 19,24 D2S441 10,11 -
STR鉴定图
参考文献
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Comprehensive analysis of BUBs gene family in lung adenocarcinoma with immunological analysis (2023-02-13)
作者:Xiaojuan Li:1.Department of Nephrology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China. ; Tianqi Wang:1.Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China. ; Mi Li:1.Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China. ; 2.Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen 518000, Guangdong, China. ; Xing Bao:1.Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China. ; Tian Ma:1.Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China. ; Caihong Yang:1.Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huaz
期刊:Comprehensive analysis of BUBs gene family in lung adenocarcinoma with immunological analysis
影响因子 :5.2
引用产品: HBE135-E6E7 细胞
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Hsa_circ_0003220 Drives Chemoresistance of Human NSCLC Cells by Modulating miR-489-3p/IGF1 (2023-06-16)
作者:Shaofeng Xia:1.Department of Thoracic Surgery, The First People's Hospital of Jiujiang City, Jiujiang, Jiangxi, China. ; Chenliang Wang:1.Department of Pathology, The First People's Hospital of Jiujiang City, Jiujiang, Jiangxi, China. ;
期刊:Hsa_circ_0003220 Drives Chemoresistance of Human NSCLC Cells by Modulating miR-489-3p/IGF1
影响因子 :2.9
引用产品: 293T [HEK-293T] 细胞 , NCI-H460 [H460] 细胞 , A549 [A-549] 细胞 , HBE135-E6E7 细胞
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Hsa_circ_0003489 Drives PTX Resistance of Human NSCLC Cells Through Modulating miR-98-5p/IGF2 (2023-09-04)
作者:Shaofeng Xia:1.Department of Thoracic Surgery, The First People's Hospital of Jiujiang City, Jiujiang, Jiangxi, People's Republic of China. ; Chenliang Wang:1.Department of Pathology, The First People's Hospital of Jiujiang City, Jiujiang, Jiangxi, People's Republic of China. ;
期刊:Hsa_circ_0003489 Drives PTX Resistance of Human NSCLC Cells Through Modulating miR-98-5p/IGF2
影响因子 :1.9
引用产品: NCI-H460 [H460] 细胞 , A549 [A-549] 细胞 , HBE135-E6E7 细胞
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Low-density lipoprotein receptor-related protein 8 facilitates the proliferation and invasion of non-small cell lung cancer cells by regulating the Wnt/β-catenin signaling pathway (2003-02-20)
作者:Zhi Fang:1.Department of Oncology, The First Affiliated Hospital of Nanchang University, Nanchang, People's Republic of China. ; 2.Department of Abdominal Oncology, Jiangxi Key Laboratory for Individualized Cancer Therapy, Nanchang, People's Republic of China. ; Min Zhong:1.Department of Oncology, The First Affiliated Hospital of Nanchang University, Nanchang, People's Republic of China. ; 2.Department of Abdominal Oncology, Jiangxi Key Laboratory for Individualized Cancer Therapy, Nanchang, People's Republic of China. ; Ling Zhou:1.Department of Oncology, The First Affiliated Hospital of Nanchang University, Nanchang, People's Republic of China. ; 2.Department of Abdominal Oncology, Jiangxi Key Laboratory for Individualized Cancer Therapy, Nanchang, People's Republic of China. ; Yi Le:1.Department of Oncology, The First Affiliated Hospital of Nanchang University, Nanchang, People's Republic of China. ; 2.Department of Abdominal Oncology, Jiangxi Key Laboratory for Individualized Ca
期刊:Low-density lipoprotein receptor-related protein 8 facilitates the proliferation and invasion of non-small cell lung cancer cells by regulating the Wnt/β-catenin signaling pathway
DOI:10.1080/21655979.2022.2036917
影响因子 :4.9
引用产品: HBE135-E6E7 细胞
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Hsa_circ_0017639 regulates cisplatin resistance and tumor growth via acting as a miR-1296-5p molecular sponge and modulating sine oculis homeobox 1 expression in non-small cell lung cancer (2003-02-20)
作者:Feiyun Chang:1.Department of Thoracic Surgery, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. ; Jiali Li:1.Department of Thoracic Surgery, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. ; Quan Sun:1.Department of Thoracic Surgery, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. ; Shuqing Wei:1.Department of Thoracic Surgery, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. ; Yongming Song:1.D
期刊:Hsa_circ_0017639 regulates cisplatin resistance and tumor growth via acting as a miR-1296-5p molecular sponge and modulating sine oculis homeobox 1 expression in non-small cell lung cancer
DOI:10.1080/21655979.2022.2053810
影响因子 :4.9
引用产品: 293T [HEK-293T] 细胞 , NCI-H460 [H460] 细胞 , NCI-H1650 细胞 , A549 [A-549] 细胞 , NCI-H1299 细胞 , HBE135-E6E7 细胞
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Lidocaine represses the malignant behavior of lung carcinoma cells via the circ_PDZD8/miR-516b-5p/GOLT1A axis (2001-02-20)
作者:Huafen Zi:1.Department of Anesthesiology, the First Affiliated Hospital of Chengdu Medical College, Sichuan, PR China. ; Li Chen:1.Department of Anesthesiology, the First Affiliated Hospital of Chengdu Medical College, Sichuan, PR China. ; Qian Ruan:1.Department of Anesthesiology, the First Affiliated Hospital of Chengdu Medical College, Sichuan, PR China. rq881231@163.com. ;
期刊:Lidocaine represses the malignant behavior of lung carcinoma cells via the circ_PDZD8/miR-516b-5p/GOLT1A axis
影响因子 :2.0
引用产品: HBE135-E6E7 细胞
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FERMT3 mediates cigarette smoke-induced epithelial–mesenchymal transition through Wnt/β-catenin signaling (2011-01-20)
作者:Xiaoshan Su:1.Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Fujian Medical University, Respirology Medicine Centre of Fujian Province, Quanzhou, China. ; Junjie Chen:1.Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ; Xiaoping Lin:1.Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Fujian Medical University, Respirology Medicine Centre of Fujian Province, Quanzhou, China. ; Xiaoyang Chen:1.Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Fujian Medical University, Respirology Medicine Centre of Fujian Province, Quanzhou, China. ; Zhixing Zhu:1.Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Fujian Medical University, Respirology Medicine Centre of Fujian Province, Quanzhou, China. ; Weijing Wu:1.Department of Pulmonary and Critical Care Medicine, The Se
期刊:FERMT3 mediates cigarette smoke-induced epithelial–mesenchymal transition through Wnt/β-catenin signaling
DOI:10.1186/s12931-021-01881-y
影响因子 :7.2
引用产品: A549 [A-549] 细胞 , HBE135-E6E7 细胞
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Vitamin E relieves chronic obstructive pulmonary disease by inhibiting COX2-mediated p-STAT3 nuclear translocation through the EGFR/MAPK signaling pathway (2011-01-20)
作者:Hui Zhao:1.Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, PR China. hui_zhao@sxmu.edu.cn. ; Jiannan Gong:1.Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, PR China. ; Lifang Li:1.Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, PR China. ; Shuyin Zhi:1.Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, PR China. ; Guang Yang:1.Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, PR China. ; Pingping Li:1.Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, PR China. ; Ruina Li:1.Department of Respiratory and Critical Care Medicine, The Second Hospital of Shanxi M
期刊:Vitamin E relieves chronic obstructive pulmonary disease by inhibiting COX2-mediated p-STAT3 nuclear translocation through the EGFR/MAPK signaling pathway
DOI:10.1038/s41374-021-00652-z
影响因子 :5.5
引用产品: HBE135-E6E7 细胞
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Circ_0017956 promotes the proliferation and metastasis of non-small cell lung cancer through regulating miR-515-5p/ITGB8 axis (2005-01-20)
作者:Na Li:1.Department of Respiratory, The Second Affiliated Hospital of Dalian Medical University, Dalian, China. ; Dan Zhu:1.Department of Respiratory, The Second Affiliated Hospital of Dalian Medical University, Dalian, China. ;
期刊:Circ_0017956 promotes the proliferation and metastasis of non-small cell lung cancer through regulating miR-515-5p/ITGB8 axis
DOI:10.1080/15384101.2021.1919829
影响因子 :4.3
引用产品: A549/DDP 细胞 , NCI-H1299 细胞 , HBE135-E6E7 细胞
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MUC13 promotes lung cancer development and progression by activating ERK signaling (2012-01-20)
作者:Yao Pang:1.Department of Thoracic Surgery No. 2, Gansu Provincial Hospital, Lanzhou, Gansu 730000, P.R. China. ; Yu Zhang:1.Department of Clinical Medicine, Gansu Health Vocational College, Lanzhou, Gansu 730000, P.R. China. ; Hong-Yi Zhang:1.Department of Thoracic Surgery No. 2, Gansu Provincial Hospital, Lanzhou, Gansu 730000, P.R. China. ; Wen-Hao Wang:1.Department of Thoracic Surgery No. 2, Gansu Provincial Hospital, Lanzhou, Gansu 730000, P.R. China. ; Gang Jin:1.Department of Thoracic Surgery No. 2, Gansu Provincial Hospital, Lanzhou, Gansu 730000, P.R. China. ; Jia-Wei Liu:1.Department of Thoracic Surgery No. 2, Gansu Provincial Hospital, Lanzhou, Gansu 730000, P.R. China. ; Zi-Jiang Zhu:1.Department of Thoracic Surgery No. 2, Gansu Provincial Hospital, Lanzhou, Gansu 730000, P.R. China. ;
期刊:MUC13 promotes lung cancer development and progression by activating ERK signaling
影响因子 :2.9
引用产品: HBE135-E6E7 细胞
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A novel EZH2/NXPH4/CDKN2A axis is involved in regulating the proliferation and migration of non-small cell lung cancer cells (2012-01-20)
作者:Zeng Yang:1.Department of Thoracic Surgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. ; Bo Wei:1.Department of Thoracic Surgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. ; Anbang Qiao:1.Department of Thoracic Surgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. ; Popo Yang:1.Department of Thoracic Surgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. ; Wenhui Chen:1.Department of Thoracic Surgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. ; Dezhi Zhen:1.Department of Thoracic Surgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. ; Xiaojian Qiu:1.Department of Respiratory Medicine, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. ;
期刊:A novel EZH2/NXPH4/CDKN2A axis is involved in regulating the proliferation and migration of non-small cell lung cancer cells
影响因子 :1.6
引用产品: HBE135-E6E7 细胞
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N-Butanol Fraction of Wenxia Formula Extract Inhibits the Growth and Invasion of Non-Small Cell Lung Cancer by Down-Regulating Sp1-Mediated MMP2 Expression (2011-00-20)
作者:QianYu Bi:1.School of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China. ; 2.College of Chinese Traditional Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China. ; MengRan Wang:1.School of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China. ; Fang Zhao:1.School of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China. ; Meng Wang:1.College of Chinese Traditional Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China. ; 2.Department of Medicine, Jining NO.1 People's Hospital, Jining, China. ; XiangJun Yin:1.School of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China. ; JiaZhao Ruan:1.School of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China. ; DeLong Wang:1.School of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, China. ; XuMing Ji:1.School of Basic Medical Science, Zhejiang Chinese Medica
期刊:N-Butanol Fraction of Wenxia Formula Extract Inhibits the Growth and Invasion of Non-Small Cell Lung Cancer by Down-Regulating Sp1-Mediated MMP2 Expression
影响因子 :5.6
引用产品: HBE135-E6E7 细胞
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Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose (2012-00-20)
作者:Jing Fei:1.Department of Oncology, The First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China. ; Chi Xiao:1.Department of Clinical Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China. ; Meiying Yang:1.Department of Clinical Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China. ; Xue Zhou:1.Department of Clinical Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China. ; Ping Gong:1.Department of Oncology, The First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China. ;
期刊:Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose
影响因子 :3.4
引用产品: HBE135-E6E7 细胞
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Luminescent ruthenium(II) polypyridyl complexes acted as radiosensitizer for pancreatic cancer by enhancing radiation-induced DNA damage (2009-09-20)
作者:Yuyang Zhou:1.School of Chemistry, Biology and Materials Engineering, Jiangsu Key Laboratory of Environmental Functional Materials, Suzhou University of Science and Technology, Suzhou, Jiangsu, 215009, P. R. China. ; Ying Xu:1.School of Radiation Medicine and Protection, State Key Laboratory of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, Jiangsu 215123, P. R. China. ; Lunjie Lu:1.Department of Radiation Physics, Qingdao Central Hospital, Qingdao, Shandong, 266000, P. R. China. ; Jingyang Ni:1.School of Chemistry, Biology and Materials Engineering, Jiangsu Key Laboratory of Environmental Functional Materials, Suzhou University of Science and Technology, Suzhou, Jiangsu, 215009, P. R. China. ; Jihua Nie:1.School of Radiation Medicine and Protection, State Key Laboratory of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, Jiangsu 215123, P. R. China. ; Jianping Cao:1.School of Radiation Medicine and Protection, St
期刊:Luminescent ruthenium(II) polypyridyl complexes acted as radiosensitizer for pancreatic cancer by enhancing radiation-induced DNA damage
影响因子 :12.4
引用产品: HBE135-E6E7 细胞
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Thymic stromal lymphopoietin induced early stage of epithelial-mesenchymal transition in human bronchial epithelial cells through upregulation of transforming growth factor beta 1 (2008-09-20)
作者:Liang-Ming Cai:1.Department of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. ; Yu-Qi Zhou:1.Department of Pulmonary Diseases, The Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou , China. ; Li-Fen Yang:1.Department of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. ; Jing-Xin Qu:1.Department of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. ; Zhen-Yuan Dai:1.Department of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. ; Hong-Tao Li:1.Department of Pulmonary Diseases, The Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou , China. ; Li Pan:1.Department of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. ; Hui-Qing Ye:1.Department of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. ; Zhuang-Gui Chen:1.Departm
期刊:Thymic stromal lymphopoietin induced early stage of epithelial-mesenchymal transition in human bronchial epithelial cells through upregulation of transforming growth factor beta 1
DOI:10.1080/01902148.2019.1646841
影响因子 :1.7
引用产品: HBE135-E6E7 细胞
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LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer (2001-07-20)
作者:Zhihong Zhao:1.Department of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University, China. Electronic address: zhihongzhao123@126.com. ; Ju Wang:1.Department of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University, China. ; Shengfa Wang:1.Department of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University, China. ; Hao Chang:1.Department of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University, China. ; Tiewa Zhang:1.Department of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University, China. ; Junfeng Qu:1.Department of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University, China. ;
期刊:LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer
DOI:10.1016/j.biopha.2016.12.122
影响因子 :7.5
引用产品: PC-9 细胞 , NCI-H358 细胞 , NCI-H1975 细胞 , HBE135-E6E7 细胞
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