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产品概述
名称 | PC-12(Undifferentiated) (大鼠肾上腺嗜铬细胞瘤细胞(未分化)) (种属鉴定正确) |
种属 | 大鼠 |
生长特性 | 疏松贴壁 |
细胞形态 | 圆形 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
注意事项 | 1.PC-12(Undifferentiated)细胞正常生长状态为悬浮聚团,若需要用NGF诱导时,需要使用多聚-L-赖氨酸溶液(货号 PB180523)包被培养瓶后促使细胞贴壁。2.Undifferentiated、Low differentiation和High differentiation的区别:Undifferentiated的PC-12从形态上看是圆形的,聚团生长的漂浮细胞;Low differentiation的成多角形,有较短的突起;High differentiation的细胞有多个突起,突起数目不等,突触较长,类似神经元轴突。3.Low differentiation和High differentiation是在Undifferentiated的PC-12基础上诱导产生的,Low differentiation和High differentiation指的与神经细胞表型的相似程度,High differentiation更接近神经细胞表型。 |
背景描述 | PC-12(Undifferentiated)细胞是来自能移植的雄性大鼠肾上腺嗜铬细胞瘤。PC-12(Undifferentiated)细胞表达神经生长因子(NGF)受体,NGF可诱导产生神经表型。PC-12(Undifferentiated)细胞不合成肾上腺素。 |
年龄(性别) | 雄性 |
组织来源 | 肾上腺嗜铬细胞瘤 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 嗜铬细胞瘤细胞 |
种属鉴定
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种属鉴定图
参考文献
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Axon-like aligned conductive CNT/GelMA hydrogel fibers combined with electrical stimulation for spinal cord injury recovery (2024-02-22)
作者:Shenglian Yao:1.School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China. ; Yongdong Yang:1.Key Laboratory of Advanced Materials of Ministry of Education, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China. ; 2.Department of Orthopedics, Dongzhimen Hospital, Beijing University of Chinese Medicine, 5 Hai Yun Cang, Beijing, 100700, China. ; Chenyu Li:1.School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China. ; Kaitan Yang:1.Department of Orthopedics, Dongzhimen Hospital, Beijing University of Chinese Medicine, 5 Hai Yun Cang, Beijing, 100700, China. ; Xin Song:1.School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China. ; Chuanhong Li:1.Department of Orthopedics, Dongzhimen Hospital, Beijing University of Chinese Medicine, 5 Hai Yun Cang, Beijing, 100700, China. ; Zheng Cao:1.
期刊:Axon-like aligned conductive CNT/GelMA hydrogel fibers combined with electrical stimulation for spinal cord injury recovery
DOI:10.1016/j.bioactmat.2024.01.021
影响因子 :18.9
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A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease (2024-01-24)
作者:Jiefei Wang:1.Henan-Macquarie Uni Joint Centre for Biomedical Innovation, Academy for Advanced Interdisciplinary Studies, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan, 475004, China. ; Ping Shangguan:1.Henan-Macquarie Uni Joint Centre for Biomedical Innovation, Academy for Advanced Interdisciplinary Studies, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan, 475004, China. ; Xiaoyu Chen:1.School of Medical Technology, Beijing Institute of Technology, Beijing, China. ; Yong Zhong:1.Key Laboratory for Special Functional Materials of Ministry of Education, National & Local Joint Engineering Research Center for High-efficiency Display and Lighting Technology, School of Materials Science and Engineering, Collaborative Innovation Center of Nano Functional Materials and Applications, Henan University, Kaifeng, 475004, China. ; Ming Lin:1.Henan-Macquarie Un
期刊:A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease
DOI:10.1038/s41467-024-44737-x
影响因子 :16.6
引用产品: PC-12 (Undifferentiated) 细胞 , BV2 细胞 , SH-SY5Y [SHSY-5Y] 细胞 , Neuro-2a [N2a; Neuro-2a] 细胞
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Enzyme-immobilized nanoclay hydrogel simultaneously reduces inflammation and scar deposition to treat spinal cord injury (2024-02-13)
作者:Tong Wu: 1.State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China; Yajun Li: 1.State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China; Zhiyan Wu: 1.State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China; Ziqiang Wang: 1.State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China; Ya Li: 1.State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China; Ke Jian: 1.State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China; Chaoyong He: 1.State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China; Can Zhang: 1.State Key Laboratory of Chemo/Biosensing and Chemomet
期刊:Enzyme-immobilized nanoclay hydrogel simultaneously reduces inflammation and scar deposition to treat spinal cord injury
影响因子 :15.1
引用产品: RAW 264.7细胞专用培养基 , BV2细胞专用培养基 (DMEM) , PC-12 (Undifferentiated) 细胞 , RAW 264.7 细胞 , BV2 细胞
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Live-cell imaging of human apurinic/apyrimidinic endonuclease 1 in the nucleus and nucleolus using a chaperone@DNA probe (2024-03-30)
作者:Xiangjian Cao:1.Beijing National Laboratory for Molecular Sciences and MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. ; Jinghui Zheng:1.Beijing National Laboratory for Molecular Sciences and MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. ; Ruilan Zhang:1.Beijing National Laboratory for Molecular Sciences and MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. ; Ying Sun:1.Beijing National Laboratory for Molecular Sciences and MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. ; Meiping Zhao:1.Beijing National Laboratory for Molecular Sciences and
期刊:Live-cell imaging of human apurinic/apyrimidinic endonuclease 1 in the nucleus and nucleolus using a chaperone@DNA probe
影响因子 :14.9
引用产品: MCF7 [MCF-7] 细胞 , PC-12 (Undifferentiated) 细胞 , PC-12 (High differentiation)细胞专用培养基
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Activation of STING signaling aggravates chronic alcohol exposure-induced cognitive impairment by increasing neuroinflammation and mitochondrial apoptosis (2024-03-22)
作者:Xinrou Lin:1.Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; 2.Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, China. ; Xiangpen Li:1.Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; 2.Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Shanwei, China. ; Chenguang Li:1.Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; Hongxuan Wang:1.Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; Lubin Zou:1.Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; 2.Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, China. ; Jingrui Pan:1.Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Gua
期刊:Activation of STING signaling aggravates chronic alcohol exposure-induced cognitive impairment by increasing neuroinflammation and mitochondrial apoptosis
影响因子 :5.5
引用产品: BV2 细胞 , PC-12 (Undifferentiated) 细胞
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Ultrasensitive detecting of dopamine in complex components by field effect transistor sensor based on the synergistic enhancement effect and overcoming debye length limitations (2024-02-17)
作者:Meng Tian: 1.School of Physics and Electronics, Shandong Normal University, Jinan 250014, China; Chonghui Li: 1.Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China; Renzhong Yu: 1.Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China; Congcong Shen: 1.Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China; Jihua Wang: 1.Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China; Jiajun Lu: 1.School of Physics and Electronics, Shandong Normal University, Jinan 250014, China; Guofeng Liu: 1.Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China; Zhenxing Wang: 1.Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China; Tiejun Wang: 1.Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezh
期刊:Ultrasensitive detecting of dopamine in complex components by field effect transistor sensor based on the synergistic enhancement effect and overcoming debye length limitations
DOI:10.1016/j.rinp.2024.107487
影响因子 :5.3
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Regulation mechanisms of sea cucumber peptides against scopolamine-induced memory disorder and novel memory-improving peptides identification (2024-02-16)
作者:Zhiqiang Lu:1.SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China; Engineering Research Center of Special Dietary Food of Liaoning Province, Food Engineering Technology Research Center of Liaoning Province, Dalian, 116034, PR China. ; Jingqi Yang:1.SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China; Engineering Research Center of Special Dietary Food of Liaoning Province, Food Engineering Technology Research Center of Liaoning Province, Dalian, 116034, PR China. ; Xiaomeng Xu:1.SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China; Engineering Research Center of Special Di
期刊:Regulation mechanisms of sea cucumber peptides against scopolamine-induced memory disorder and novel memory-improving peptides identification
DOI:10.1016/j.ejphar.2024.176430
影响因子 :5.0
引用产品: PC-12 (Undifferentiated) 细胞 , PC-12 (Undifferentiated)细胞专用培养基
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Two new quinoline alkaloid with neuroprotective activities from Xylaria longipes (2024-03-28)
作者:Tao-Hai Liu:1.Department of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China. ; Xia Xu:1.Department of General Practice, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China. ; Lan-Qing Li:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, PR China. ; Yu-Fen Tan:1.Department of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China. ; Si-Qian Zhou:1.The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, PR China. ; Shao Liu:1.Department of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China. ; Hong-Ping Long:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, PR China. ; Wen-Xuan Wang:1.X
期刊:Two new quinoline alkaloid with neuroprotective activities from Xylaria longipes
DOI:10.1016/j.fitote.2024.105930
影响因子 :3.4
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Development of Cholinesterase-Activatable Fluorescent Probes for Pesticide Residue Detection (2024-02-28)
作者:Yuanxiang Li: 1.College of Chemistry and Materials Engineering, Huaihua University, Huaihua 418008, P.R. China; Zi-Ye Zhang: 1.National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, P. R. China; Shuang-Yu Li: 1.National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, P. R. China; Xue-Yan Gong: 1.National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, P. R. China; Wen-Chao Yang: 1.College of Chemistry and Materials Engineering, Huaihua University, Huaihua 418008, P.R. China;
期刊:Development of Cholinesterase-Activatable Fluorescent Probes for Pesticide Residue Detection
DOI:10.1021/acsagscitech.3c00466
影响因子 :2.5
引用产品: PC-12 (Undifferentiated) 细胞 , OLN93 细胞
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Photoinhibiting via simultaneous photoabsorption and free-radical reaction for high-fidelity light-based bioprinting (2023-05-27)
作者:Ning He:1.National Engineering Research Centre for High Efficiency Grinding, Hunan University, 410082, Changsha, China. ; 2.State Key Laboratory of Advanced Design and Manufacture for Vehicle Body, Hunan University, 410082, Changsha, China. ; Xiaonan Wang:1.College of Biology, Hunan University, 410082, Changsha, China. ; Liyang Shi:1.College of Biology, Hunan University, 410082, Changsha, China. ; Jing Li:1.National Engineering Research Centre for High Efficiency Grinding, Hunan University, 410082, Changsha, China. ; Lan Mo:1.College of Food Science and Technology, Hunan Agricultural University, 410128, Changsha, China. ; Feng Chen:1.National Engineering Research Centre for High Efficiency Grinding, Hunan University, 410082, Changsha, China. fchen@hnu.edu.cn. ; Yuting Huang:1.College of Material Science and Engineering, Hunan University, 410082, Changsha, China. ; Hairong Liu:1.College of Material Science and Engineering, Hunan University, 410082, Changsha, China. ; Xiaolong Zh
期刊:Photoinhibiting via simultaneous photoabsorption and free-radical reaction for high-fidelity light-based bioprinting
DOI:10.1038/s41467-023-38838-2
影响因子 :16.6
引用产品: PC-12 (Undifferentiated) 细胞 , Hep G2 细胞
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Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy (2023-02-10)
作者:Ting-Ting Zhu:1.Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ; 2.Neuroscience Research InstituteZhengzhou University Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450052, China. ; He Wang:1.Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ; Han-Wen Gu:1.Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ; 2.Neuroscience Research InstituteZhengzhou University Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450052, China. ; Ling-Sha Ju:1.Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ; Xin-Miao Wu:1.Department of Anesthesiology, Pain and Perioperative Medicine, The First Affili
期刊:Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy
DOI:10.1186/s12951-023-01807-4
影响因子 :10.2
引用产品: PC-12 (Undifferentiated) 细胞 , MEM (含NEAA) 培养基 , 特级胎牛血清
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Plant Protein-Peptide Supramolecular Polymers with Reliable Tissue Adhesion for Surgical Sealing (2023-03-24)
作者:Junlian Nie:1.State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun, 130012, P. R. China. ; Yingchuan Sun:1.Department of Orthopedics, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin Province, 130014, P. R. China. ; Xueliang Cheng:1.Department of Orthopedics, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin Province, 130014, P. R. China. ; Guang Wen:1.State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun, 130012, P. R. China. ; Xiaohuan Liu:1.State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun, 130012, P. R. China. ; Meng Cheng:1.Department of Orthopedics, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Ji
期刊:Plant Protein-Peptide Supramolecular Polymers with Reliable Tissue Adhesion for Surgical Sealing
影响因子 :10.0
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The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis (2023-05-18)
作者:Jia Liu:1.Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou 510280, China. ; Zhendong Huang:1.Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou 510280, China. ; Suhan Yin:1.Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou 510280, China. ; Xinru Zhou:1.Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou 510280, China. ; Yanping Jiang:1.Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou 510280, China. ; Longquan Shao:1.Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou 510280, China. Electronic address: shaolongquan@smu.edu.cn. ;
期刊:The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis
DOI:10.1016/j.scitotenv.2023.164078
影响因子 :9.8
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An electrical microenvironment constructed based on electromagnetic induction stimulates neural differentiation (2023-03-13)
作者:Fangwei Qi: 1.Institute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, China E-mail: shuai@csu.edu.cn;2.State Key Lab of Polymer Materials Engineering, Polymer Research Institute, Sichuan University, Chengdu, China; Ruobing Liao: 1.Institute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, China E-mail: shuai@csu.edu.cn; ** Wu: 1.School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China; Huixing Li: 1.Institute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, China E-mail: shuai@csu.edu.cn; Jun Zan: 1.Institute of Bioadditive
期刊:An electrical microenvironment constructed based on electromagnetic induction stimulates neural differentiation
影响因子 :7.0
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Low beauvericin concentrations promote PC-12 cell survival under oxidative stress by regulating lipid metabolism and PI3K/AKT/mTOR signaling (2023-12-07)
作者:Liming Hu:1.College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China. ; Xintong Sui:1.College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China. ; Xin Dong:1.College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China. ; Zhimeng Li:1.College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China. ; Shiyi Lun:1.College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China. ; Shumin Wang:1.College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China. Electronic address: wangsm@ccucm.edu.cn. ;
期刊:Low beauvericin concentrations promote PC-12 cell survival under oxidative stress by regulating lipid metabolism and PI3K/AKT/mTOR signaling
DOI:10.1016/j.ecoenv.2023.115786
影响因子 :6.8
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IL-11 ameliorates oxidative stress damage in neurons after spinal cord injury by activating the JAK/STAT signaling pathway (2023-12-30)
作者:Yang Sun:1.Department of rehabilitation medicine, First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China. ; Xue Song:1.Department of Central Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China; Inflammatory Bowel Disease Research Center, First Affiliated Hospital of Bengbu Medical University, Bengbu, China; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-related Diseases, Bengbu, China. ; Zhijun Geng:1.Department of Central Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China; Inflammatory Bowel Disease Research Center, First Affiliated Hospital of Bengbu Medical University, Bengbu, China; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-related Diseases, Bengbu, China. ; Yibo Xu:1.Bengbu Medical University, Bengbu, China. ; Linyu Xiao:1.Department of rehabilitation medicine, First Affiliated Hospital of Bengbu Medical University, Bengb
期刊:IL-11 ameliorates oxidative stress damage in neurons after spinal cord injury by activating the JAK/STAT signaling pathway
DOI:10.1016/j.intimp.2023.111367
影响因子 :5.6
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Ameliorative effect of scopolamine-induced cognitive dysfunction by Fufangmuniziqi formula: The roles of alkaloids, saponins, and flavonoids (2023-06-24)
作者:Xiang Zhao:1.Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Rood, Shanghai, 201203, China. ; Xianrun Hu:1.Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Rood, Shanghai, 201203, China. ; Qi Xie:1.Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Rood, Shanghai, 201203, China. ; Shenglan Qi:1.Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardiza
期刊:Ameliorative effect of scopolamine-induced cognitive dysfunction by Fufangmuniziqi formula: The roles of alkaloids, saponins, and flavonoids
影响因子 :5.4
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Sanpian decoction ameliorates cerebral ischemia-reperfusion injury by regulating SIRT1/ERK/HIF-1α pathway through in silico analysis and experimental validation (2023-07-17)
作者:Tong Yang:1.Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China. ; Xiaolu Liu:1.Third-Grade Pharmacological Laboratory on Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, College of Medicine and Health Sciences, China Three Gorges University, Yichang, 443002, Hubei, China; State Key Laboratory of Natural Medicines and School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, Jiangsu, China. ; Yue Zhou:1.Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China. ; Lipeng Du:1.Thi
期刊:Sanpian decoction ameliorates cerebral ischemia-reperfusion injury by regulating SIRT1/ERK/HIF-1α pathway through in silico analysis and experimental validation
影响因子 :5.4
引用产品: PC-12 (Undifferentiated) 细胞 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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Dandelion (Taraxacum mongolicum) Extract Alleviated H2O2-Induced Oxidative Damage: The Underlying Mechanism Revealed by Metabolomics and Lipidomics (2023-09-03)
作者:Yannan Chen:1.Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Qinggongyuan, Gangjingzi District, Dalian 116034, China. ; 2.National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China. ; Siyuan Fei:1.Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Qinggongyuan, Gangjingzi District, Dalian 116034, China. ; 2.National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China. ; Xiaoting Yu:1.Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Qinggongyuan, Gangjingzi District, Dalian 116034, China. ; 2.National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China. ; Mingqian Tan:1.Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic Univer
期刊:Dandelion (Taraxacum mongolicum) Extract Alleviated H2O2-Induced Oxidative Damage: The Underlying Mechanism Revealed by Metabolomics and Lipidomics
影响因子 :5.2
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Two New Compounds from the Fungus Xylaria nigripes (2023-01-04)
作者:Hongping Long:1.The First Hospital of Hunan University of Chinese Medicine, Center for Medical Research and Innovation, Changsha 410007, China. ; Siqian Zhou:1.The First Hospital of Hunan University of Chinese Medicine, Center for Medical Research and Innovation, Changsha 410007, China. ; Lanqing Li:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China. ; Jing Li:1.Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China. ; 2.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China. ; Jikai Liu:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China. ;
期刊:Two New Compounds from the Fungus Xylaria nigripes
影响因子 :4.6
引用产品: 特级胎牛血清 , PC-12 (Undifferentiated) 细胞
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Gastrodin Induces Ferroptosis of Glioma Cells via Upregulation of Homeobox D10 (2023-12-13)
作者:Wenpeng Cao:1.Department of Anatomy, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; 2.Key Laboratory of Human Brain Bank for Functions and Diseases, Guizhou Medical University, Guiyang 550025, China. ; Jinzhi Lan:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Zhirui Zeng:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Wenfeng Yu:1.Department of Anatomy, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; 2.Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550025, China. ; 3.Key Laboratory of Medical Molecular Biology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ; Shan Lei:1.Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang 550025, China. ;
期刊:Gastrodin Induces Ferroptosis of Glioma Cells via Upregulation of Homeobox D10
影响因子 :4.6
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Characterization of Polysaccharides from the Pericarp of Zanthoxylum bungeanum Maxim by Saccharide Mapping and Their Neuroprotective Effects (2023-02-15)
作者:Mei-Bian Hu:1.Institute of Pharmaceutical & Food Engineering, Shanxi University of Chinese Medicine, Jinzhong 030619, China. ; 2.Key Laboratory of Traditional Chinese Medicine Processing of Shanxi Province, Shanxi University of Chinese Medicine, Jinzhong 030619, China. ; Kui-Xu Gao:1.Institute of Pharmaceutical & Food Engineering, Shanxi University of Chinese Medicine, Jinzhong 030619, China. ; 2.Key Laboratory of Traditional Chinese Medicine Processing of Shanxi Province, Shanxi University of Chinese Medicine, Jinzhong 030619, China. ; Yao Wang:1.Institute of Pharmaceutical & Food Engineering, Shanxi University of Chinese Medicine, Jinzhong 030619, China. ; 2.Key Laboratory of Traditional Chinese Medicine Processing of Shanxi Province, Shanxi University of Chinese Medicine, Jinzhong 030619, China. ; Yu-Jie Liu:1.Institute of Pharmaceutical & Food Engineering, Shanxi University of Chinese Medicine, Jinzhong 030619, China. ; 2.Key Laboratory of Traditional Chinese Medicine Processing
期刊:Characterization of Polysaccharides from the Pericarp of Zanthoxylum bungeanum Maxim by Saccharide Mapping and Their Neuroprotective Effects
影响因子 :4.6
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Enhancing both oral bioavailability and anti-ischemic stroke efficacy of ginkgolide B by preparing nanocrystals self-stabilized Pickering nano-emulsion (2023-10-21)
作者:Yun Liu: 1.School of Pharmacy, Liaoning University of Traditional Chinese Medicine, No. 77, Life One Road DD port, Dalian 116600, China; Chungang Zhang: 1.School of Pharmacy, Liaoning University of Traditional Chinese Medicine, No. 77, Life One Road DD port, Dalian 116600, China;2.Department of Pharmacy, Changzhi Medical College, Changzhi, China;3.Key Laboratory of Ministry of Education, Traditional Chinese Medicine Viscera-State Theory and Applications, Liaoning University of Traditional Chinese Medicine, Shenyang, China;4.Qimeng Co., LTD, Chifeng, China; Lan Cheng: 1.School of Pharmacy, Liaoning University of Traditional Chinese Medicine, No. 77, Life One Road DD port, Dalian 116600, China; Hongxin Wang: 1.Key Laboratory of Cardiovascular and Cerebrovascular Drug Research of Liaoning Province, Jinzhou Medical University, Jinzhou, Liaoning Province, China; Meili Lu: 1.Key Laboratory of Cardiovascular and Cerebrovascular Drug Research of Liaoning Province, Jinzhou Medical University, J
期刊:Enhancing both oral bioavailability and anti-ischemic stroke efficacy of ginkgolide B by preparing nanocrystals self-stabilized Pickering nano-emulsion
DOI:10.1016/j.ejps.2023.106620
影响因子 :4.6
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Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model (2023-05-06)
作者:Luchen Yang:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Zhengju Ren:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; 2.Department of Urology, the Second affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China. ; Pan Song:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Zhenghuan Liu:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Zhufeng Peng:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Jing Zhou:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Qiang Dong:1.Department of Urology, Institute of
期刊:Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model
DOI:10.1007/s11064-023-03946-4
影响因子 :4.4
引用产品: PC-12 (Undifferentiated) 细胞 , RSC96 细胞
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Bioinformatics and experimental analyses of glutamate receptor and its targets genes in myocardial and cerebral ischemia (2023-06-02)
作者:Wei Liao:1.Medical College of Soochow University, Suzhou, Jiangsu, China. ; 2.Department of Neurosurgery, First Affiliated of Gannan Medical University, Ganzhou, Jiangxi, China. ; 3.Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, Jiangxi, China. ; Chunming He:1.Department of Neurosurgery, First Affiliated of Gannan Medical University, Ganzhou, Jiangxi, China. ; 2.Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, Jiangxi, China. ; Shaochun Yang:1.Department of Neurosurgery, First Affiliated of Gannan Medical University, Ganzhou, Jiangxi, China. ; 2.Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, Jiangxi, China. ; Man Zhou:1.Gannan Medical University, Ganzhou, Jiangxi, China. ; Chuan Z
期刊:Bioinformatics and experimental analyses of glutamate receptor and its targets genes in myocardial and cerebral ischemia
DOI:10.1186/s12864-023-09408-z
影响因子 :4.4
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Downregulation of Preso protects against ischemic/reperfusion-mediated neuronal injury through regulating PSD95-nNOS/YAP pathways (2023-07-12)
作者:Rundong Chen:1.Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. ; Lei Qian:1.Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. ; Jin Fu:1.Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. ; Jiajun Qin:1.Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. ; Xianzhen Chen:1.Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. Electronic address: chenxianzheny@126.com. ; Xiaolong Xu:1.Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. Electronic address: dr_xxlong@163.com. ;
期刊:Downregulation of Preso protects against ischemic/reperfusion-mediated neuronal injury through regulating PSD95-nNOS/YAP pathways
DOI:10.1016/j.neuint.2023.105586
影响因子 :4.2
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Neuroprotective methylsuccinic acid and enoic acid derivatives from the fungus Xylaria longipes (2023-03-24)
作者:Jing Li:1.Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, PR China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, PR China. ; Yu-Fen Tan:1.Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, PR China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, PR China. ; Si-Qian Zhou:1.The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410007, PR China. ; Shao Liu:1.Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, PR China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, PR China. ; Wen-Xuan Wang:1.Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, PR China. ; Yue-Ping Jiang:1.Departmen
期刊:Neuroprotective methylsuccinic acid and enoic acid derivatives from the fungus Xylaria longipes
DOI:10.1016/j.phytochem.2023.113652
影响因子 :3.8
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Integrated insight into the molecular mechanisms of selenium-modulated, MPP+-induced cytotoxicity in a Parkinson’s disease model (2023-05-24)
作者:Wen Liu:1.Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Donghu Road 169, Wuhan 430071, China. ; Feiyang Zhang:1.Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Donghu Road 169, Wuhan 430071, China. ; Wu Liang:1.Department of Neurosurgery, Minda Hospital of Hubei Minzu University, Enshi 445000, China. ; Kaixin Huang:1.Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Donghu Road 169, Wuhan 430071, China. ; Chenguang Jia:1.Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Donghu Road 169, Wuhan 430071, China. ; Jie Zhang:1.Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Donghu Road 169, Wuhan 430071, China. ; Xiang Li:1.Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Donghu Road 169, Wuhan 430071, China; Neuroepigenetic Research Lab, Medical Research Institute, Wuhan University, Donghu Road 115, Wuhan 430071, China. ; Wei Wei:1.Department of Neurosurgery, Zhongnan Hospital, Wuhan Un
期刊:Integrated insight into the molecular mechanisms of selenium-modulated, MPP+-induced cytotoxicity in a Parkinson’s disease model
DOI:10.1016/j.jtemb.2023.127208
影响因子 :3.5
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Doping Ag2S quantum dots with Pb yields significantly enhanced in vivo fluorescence imaging in the NIR-II window and comparable toxic effects (2023-07-26)
作者:Qingyuan Cheng: 1.Department of Andrology/Sichuan Human Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China; Liman Li: 1.Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Mingxia Yu: 1.Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China E-mail: dewrosy520@whu.edu.cn;
期刊:Doping Ag2S quantum dots with Pb yields significantly enhanced in vivo fluorescence imaging in the NIR-II window and comparable toxic effects
影响因子 :3.3
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METTL3 silenced inhibited the ferroptosis development via regulating the TFRC levels in the Intracerebral hemorrhage progression (2023-04-25)
作者:Liu Zhang:1.Department of Neurosurgery, The First Affiliated Hospital of Jinan University, China. ; Xiangyu Wang:1.Department of Neurosurgery, The First Affiliated Hospital of Jinan University, China. ; Wenqiang Che:1.Department of Neurosurgery, The First Affiliated Hospital of Jinan University, China. ; Shuoming Zhou:1.Department of Neurosurgery, The First Affiliated Hospital of Jinan University, China. ; Yongjian Feng:1.Department of Neurosurgery, The First Affiliated Hospital of Jinan University, China. Electronic address: horse1980@163.com. ;
期刊:METTL3 silenced inhibited the ferroptosis development via regulating the TFRC levels in the Intracerebral hemorrhage progression
DOI:10.1016/j.brainres.2023.148373
影响因子 :2.9
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Umbilical mesenchymal stem cell-derived exosomes promote spinal cord functional recovery through the miR-146b/TLR4 -mediated NF-κB p65 signaling pathway in rats (2023-07-20)
作者:Xiujuan Wang:1.Technology Department, Everunion Biotechnology Co. LTD, Tianjin, China. ; Ying Yang:1.Technology Department, Everunion Biotechnology Co. LTD, Tianjin, China. ; Wei Li:1.Technology Department, Everunion Biotechnology Co. LTD, Tianjin, China. ; MingYuan Hao:1.Technology Department, Everunion Biotechnology Co. LTD, Tianjin, China. ; YongSheng Xu:1.Technology Department, Everunion Biotechnology Co. LTD, Tianjin, China. ;
期刊:Umbilical mesenchymal stem cell-derived exosomes promote spinal cord functional recovery through the miR-146b/TLR4 -mediated NF-κB p65 signaling pathway in rats
DOI:10.1016/j.bbrep.2023.101497
影响因子 :2.7
引用产品: 人脐带间充质干细胞 , PC-12 (Undifferentiated) 细胞
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STIM2 Suppression Blocks Glial Activation to Alleviate Brain Ischemia Reperfusion Injury via Inhibition of Inflammation and Pyroptosis (2023-08-12)
作者:Xihong Ye:1.Department of Anesthesiology&Institute of Neuroscience and Brain Diseases, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Jingzhou Road 136, Xiangcheng District, Xiangyang, Hubei, 441021, China. ; Qinyi Chen:1.Department of Anesthesiology&Institute of Neuroscience and Brain Diseases, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Jingzhou Road 136, Xiangcheng District, Xiangyang, Hubei, 441021, China. ; Xingrui Gong:1.Department of Anesthesiology&Institute of Neuroscience and Brain Diseases, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Jingzhou Road 136, Xiangcheng District, Xiangyang, Hubei, 441021, China. ; Chunli Zhou:1.Department of Anesthesiology&Institute of Neuroscience and Brain Diseases, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Jingzhou Road 136, Xiangcheng District, Xiangyang, Hubei, 4410
期刊:STIM2 Suppression Blocks Glial Activation to Alleviate Brain Ischemia Reperfusion Injury via Inhibition of Inflammation and Pyroptosis
DOI:10.1007/s12033-023-00823-x
影响因子 :2.6
引用产品: BV2 细胞 , PC-12 (Undifferentiated) 细胞
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Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2 (2023-06-30)
作者:Yingju Wang:1.Department of Neurology, the First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Harbin 150001, Heilongjiang Province, PR China. ; Hongping Chen:1.Department of Neurology, the First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Harbin 150001, Heilongjiang Province, PR China. ; Xuehui Fan:1.Department of Neurology, the First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Harbin 150001, Heilongjiang Province, PR China. ; Chen Xu:1.Department of Neurology, the First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Harbin 150001, Heilongjiang Province, PR China. ; Meng Li:1.Department of Neurology, the First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Harbin 150001, Heilongjiang Province, PR China. ; Hongxue Sun:1.Department of Neurology, the First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Harbin 150001, Heilongjiang Province,
期刊:Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2
DOI:10.1016/j.jstrokecerebrovasdis.2023.107235
影响因子 :2.5
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Two pairs of new isobenzofuranone enantiomers from a soil-derived fungus Penicillium canescens DWS225 (2023-04-11)
作者:Jing Wang:1.Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, PR China. ; 2.Hunan Key laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Central South University, Changsha, Hunan, PR China. ; Xiao-Qian Wu:1.Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, PR China. ; 2.Hunan Key laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Central South University, Changsha, Hunan, PR China. ; Ji-Song Mo:1.Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, PR China. ; 2.Hunan Key laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Central South University, Changsha, Hunan, PR China. ; Yu-Fen Tan:1.Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, PR China. ; 2.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan,
期刊:Two pairs of new isobenzofuranone enantiomers from a soil-derived fungus Penicillium canescens DWS225
DOI:10.1080/14786419.2023.2198712
影响因子 :2.2
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Inhibition of TERC inhibits neural apoptosis and inflammation in spinal cord injury through Akt activation and p-38 inhibition via the miR-34a-5p/XBP-1 axis (2023-01-24)
作者:Weiguo Ding:1.Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China. ; Weixing Xu:1.Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China. ; Di Lu:1.Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China. ; Hongfeng Sheng:1.Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China. ; Xinwei Xu:1.Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China. ; Bin Xu:1.Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China. ; Aote Zheng:1.Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China. ;
期刊:Inhibition of TERC inhibits neural apoptosis and inflammation in spinal cord injury through Akt activation and p-38 inhibition via the miR-34a-5p/XBP-1 axis
影响因子 :2.1
引用产品: PC-12 (Undifferentiated) 细胞 , 马血清
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Combining a Density Gradient of Biomacromolecular Nanoparticles with Biological Effectors in an Electrospun Fiber-Based Nerve Guidance Conduit to Promote Peripheral Nerve Repair (2022-12-09)
作者:Binghui Jin:1.Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, 100029, P. R. China. ; 2.Oujiang Laboratory, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. ; Yiling Yu:1.Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, 100029, P. R. China. ; Chenghao Lou:1.Oujiang Laboratory, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. ; Xiaodi Zhang:1.Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, 100029, P. R. China. ; Bowen Gong:1.Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, 100029, P. R. China. ; Jinghao Chen:1
期刊:Combining a Density Gradient of Biomacromolecular Nanoparticles with Biological Effectors in an Electrospun Fiber-Based Nerve Guidance Conduit to Promote Peripheral Nerve Repair
影响因子 :17.5
引用产品: PC-12 (Undifferentiated) 细胞 , 多聚-L-赖氨酸溶液 (10×) , PC-12 (Undifferentiated)细胞专用培养基
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Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice (2002-02-20)
作者:Libin Ni:1.Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ; 2.Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, Zhejiang Province, China. ; 3.The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ; Jian Xiao:1.Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ; 2.Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, Zhejiang Province, China. ; 3.The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ; Di Zhang:1.Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ; 2.Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, Zhejiang Province, China. ; 3.The Second Schoo
期刊:Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice
DOI:10.1038/s41419-022-04592-4
影响因子 :9.0
引用产品: BV2 细胞 , PC-12 (Undifferentiated) 细胞
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Antidepressant-like effects of geniposide in chronic unpredictable mild stress-induced mice by regulating the circ_0008405/miR-25-3p/Gata2 and Oip5os1/miR-25-3p/Gata2 networks (2022-12-14)
作者:Yu Zhao:1.Department of Acupuncture, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, PR China. ; Qian Zhang:1.Department of Acupuncture, Second Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, PR China. ; Yuzhu Yan:1.Department of Acupuncture, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, PR China. ; Xinbo Wang:1.Department of Acupuncture, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, PR China. ; Yin Shao:1.Department of Acupuncture, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, PR China. ; Cheng Mei:1.Department of Encephalopathy, Heilongjiang Academy of Chinese Medical Sciences, Harbin, PR China. ; Tianyu Zou:1.Department of Encephalopathy, Shenzhen Hospital of Shanghai University of Traditional Chinese Medicine, Shenzhen, PR China. ;
期刊:Antidepressant-like effects of geniposide in chronic unpredictable mild stress-induced mice by regulating the circ_0008405/miR-25-3p/Gata2 and Oip5os1/miR-25-3p/Gata2 networks
DOI:10.1002/ptr.7702
影响因子 :6.4
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Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury (2022-12-22)
作者:Zhenxin Hu:1.Department of Orthopedics, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China. ; Lina Xuan:1.Department of Neurosurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China. ; Tingting Wu:1.The First Clinical Medical Colloge, Wenzhou Medical University, Wenzhou 325035, China. ; Nizhou Jiang:1.Department of Orthopedics, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China. ; Xiangjun Liu:1.Department of Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China. ; Jiazhen Chang:1.Advanced Institute for Medical Sciences, Dalian Medical University, Dalian 116044, China. ; Te Wang:1.Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325088, China. ; Nan Han:1.Department of Ultrasonography, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China. Elect
期刊:Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury
DOI:10.1016/j.intimp.2022.109616
影响因子 :5.7
引用产品: BV2 细胞 , PC-12 (Undifferentiated) 细胞
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The SWGEDWGEIW from Soybean Peptides Reduce Oxidative Damage-Mediated Apoptosis in PC-12 Cells by Activating SIRT3/FOXO3a Signaling Pathway (2022-11-06)
作者:Guofu Yi:1.College of Biology and Food Engineering, Chuzhou University, Chuzhou 239000, China. ; Mengyue Zhou:1.College of Biology and Food Engineering, Chuzhou University, Chuzhou 239000, China. ; Qingfei Du:1.College of Biology and Food Engineering, Chuzhou University, Chuzhou 239000, China. ; Shuibing Yang:1.College of Biology and Food Engineering, Chuzhou University, Chuzhou 239000, China. ; Yuxia Zhu:1.College of Biology and Food Engineering, Chuzhou University, Chuzhou 239000, China. ; Yining Dong:1.College of Biology and Food Engineering, Chuzhou University, Chuzhou 239000, China. ; Yang Liu:1.College of Biology and Food Engineering, Chuzhou University, Chuzhou 239000, China. ; He Li:1.Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University (BTBU), Beijing 100048, China. ; You Li:1.Beijing Advanced Innovation Center for Food Nutrition and Human
期刊:The SWGEDWGEIW from Soybean Peptides Reduce Oxidative Damage-Mediated Apoptosis in PC-12 Cells by Activating SIRT3/FOXO3a Signaling Pathway
影响因子 :4.9
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Calycosin ameliorates spinal cord injury by targeting Hsp90 to inhibit oxidative stress and apoptosis of nerve cells (2022-11-17)
作者:Mingdong Li:1.Department of Orthopaedics and Traumatology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, 570311 Hainan Province, China. ; Hasiqiqige:1.Inner Mongolia innovative Engineering Research Center, Hohhot, 010060 Inner Mongolia, China. ; Yanqiang Huan:1.Department of Spine Surgery, Inner Mongolia People's Hospital, Hohhot, 010017 Inner Mongolia, China. ; Xiaolei Wang:1.Department of Spine Surgery, Inner Mongolia People's Hospital, Hohhot, 010017 Inner Mongolia, China. ; Mingkai Tao:1.Department of Spine Surgery, Inner Mongolia People's Hospital, Hohhot, 010017 Inner Mongolia, China. ; Tianqi Jiang:1.Department of Spine Surgery, Inner Mongolia People's Hospital, Hohhot, 010017 Inner Mongolia, China. ; Hongbin Xie:1.Department of Spine Surgery, Inner Mongolia People's Hospital, Hohhot, 010017 Inner Mongolia, China. ; Wu Jisiguleng:1.Department of Spine Surgery, Inner Mongolia People's Hospital, Hohhot, 010017 Inner Mongolia, Chin
期刊:Calycosin ameliorates spinal cord injury by targeting Hsp90 to inhibit oxidative stress and apoptosis of nerve cells
DOI:10.1016/j.jchemneu.2022.102190
影响因子 :3.1
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miR‑222-3p reduces neuronal cell apoptosis and alleviates spinal cord injury by inhibiting Bbc3 and Bim (2022-10-31)
作者:Qiangqiang Zhang:1.Department of Orthopedics, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou 121000, China. ; Gang Li:1.Department of Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Qingdao 266035, China. ; Jundong Kong:1.Department of Orthopedics, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou 121000, China. ; Junyu Dai:1.Department of Orthopedics, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou 121000, China. ; Zhongkai Fan:1.Department of Orthopedics, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou 121000, China. Electronic address: fanzk_ln@163.com. ; Jian Li:1.Department of Orthopedics, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou 121000, China. Electronic address: jk1403928214@163.com. ;
期刊:miR‑222-3p reduces neuronal cell apoptosis and alleviates spinal cord injury by inhibiting Bbc3 and Bim
DOI:10.1016/j.neures.2022.10.008
影响因子 :2.9
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Fabrication and detection of a novel hybrid conductive scaffold based on alginate/gelatin/carboxylated carbon nanotubes (Alg/Gel/mMWCNTs) for neural tissue engineering (2022-12-07)
作者:Hailin Ma:1.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China. ; Kai Yu:1.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China. ; Hao Wang:1.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China. ; Jiaqi Liu:1.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China. ; Yuen Yee Cheng:1.Institute for Biomedical Materials and Devices, Faculty of Science, University of Technology Sydney, NSW 2007, Australia. ; Yue Kang:1.Department of Breast Surgery, Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital & Institute, Shenyang 110042, China. Electronic address: kangyue@cancerhosp-ln-c
期刊:Fabrication and detection of a novel hybrid conductive scaffold based on alginate/gelatin/carboxylated carbon nanotubes (Alg/Gel/mMWCNTs) for neural tissue engineering
DOI:10.1016/j.tice.2022.101995
影响因子 :2.6
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Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo (2001-02-20)
作者:Dan Zhang:1.Department of Pharmacology, School of Pharmacy, Southwest Medical University. ; 2.Pharmaceutical Department of Traditional Chinese Medicine, School of Pharmacy, Southwest Medical University. ; Xiaofang Li:1.Department of Pharmacology, School of Pharmacy, Southwest Medical University. ; 2.Department of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China. ; Daqiang Song:1.Department of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China. ; Siwei Chen:1.Pharmaceutical Department of Traditional Chinese Medicine, School of Pharmacy, Southwest Medical University. ; Zhuo Zhang:1.Department of Pharmacology, School of Pharmacy, Southwest Medical University. ; Shousong Cao:1.Department of Pharmacology, School of Pharmacy, Southwest Medical University. ; Minghua Liu:1.Department of Pharmacology, School of Pharmacy, Southwest Medical University. ;
期刊:Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo
DOI:10.1097/CAD.0000000000001136
影响因子 :2.3
引用产品: HCT 116 细胞 , A549 [A-549] 细胞 , Hep G2 细胞 , PC-12 (Undifferentiated) 细胞
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Macroscopic Supramolecular Assembly Strategy to Construct 3D Biocompatible Microenvironments with Site-Selective Cell Adhesion (2006-01-20)
作者:Changyu Wang:1.State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, China. ; Cuiling Lin:1.State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, China. ; Rui Ming:1.State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, China. ; Xiangxin Li:1.State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Techn
期刊:Macroscopic Supramolecular Assembly Strategy to Construct 3D Biocompatible Microenvironments with Site-Selective Cell Adhesion
影响因子 :9.5
引用产品: MG-63 细胞 , PC-12 (Undifferentiated) 细胞 , 重组人胰岛素溶液 (10mg/mL) , MEM非必需氨基酸溶液 (NEAA),100× , PUMC-HUVEC-T1 , CCC-SMC-1 细胞
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Protective effect of plastrum testudinis extract on dopaminergic neurons in a Parkinsons disease model through DNMT1 nuclear translocation and SNCAs methylation (2006-01-20)
作者:Sen Ye:1.School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China; Department of Human Anatomy, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China; Research Center of Integrative Medicine (Key Laboratory of Chinese Medicine Pathogenesis and Therapy Research), School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, PR China. ; Jun Zhong:1.School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China; Department of Human Anatomy, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China; Research Center of Integrative Medicine (Key Laboratory of Chinese Medicine Pathogenesis and Therapy Research), School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 51
期刊:Protective effect of plastrum testudinis extract on dopaminergic neurons in a Parkinsons disease model through DNMT1 nuclear translocation and SNCAs methylation
DOI:10.1016/j.biopha.2021.111832
影响因子 :7.5
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Neuroprotective effects of NDEELNK from sea cucumber ovum against scopolamine-induced PC12 cell damage through enhancing energy metabolism and upregulation of the PKA/BDNF/NGF signaling pathway (2006-01-20)
作者:Yue Zhao:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P. R. China. linsongyi730@163.com. ; Yifei Dong: Qi Ge: Pengbo Cui: Na Sun: Songyi Lin:
期刊:Neuroprotective effects of NDEELNK from sea cucumber ovum against scopolamine-induced PC12 cell damage through enhancing energy metabolism and upregulation of the PKA/BDNF/NGF signaling pathway
影响因子 :6.1
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A novel nonapeptide SSDAFFPFR from Antarctic krill exerts a protective effect on PC12 cells through the BCL-XL/Bax/Caspase-3/p53 signaling pathway (2008-01-20)
作者:Jingru Zheng: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China; Mengqi Li: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China; Chuanzhi Wang: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China; Na Sun: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China;2.Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian, 116034, PR China; Songyi Lin: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, PR China;2.Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic Univers
期刊:A novel nonapeptide SSDAFFPFR from Antarctic krill exerts a protective effect on PC12 cells through the BCL-XL/Bax/Caspase-3/p53 signaling pathway
DOI:10.1016/j.fbio.2021.101345
影响因子 :5.2
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Adipose Mesenchymal Stem Cell-Derived Exosomes Enhance PC12 Cell Function through the Activation of the PI3K/AKT Pathway (2010-01-20)
作者:Yong Xie:1.Department of Obstetrics and Gynecology, The First People's Hospital of Foshan, Foshan 528000, China. ; Yangping Chen:1.Department of Obstetrics and Gynecology, The First People's Hospital of Foshan, Foshan 528000, China. ; Yuyuan Zhu:1.Department of Obstetrics and Gynecology, The First People's Hospital of Foshan, Foshan 528000, China. ; Xia Chen:1.Department of Obstetrics and Gynecology, The First People's Hospital of Foshan, Foshan 528000, China. ; Tiecheng Lin:1.Department of Obstetrics and Gynecology, The First People's Hospital of Foshan, Foshan 528000, China. ; Dan Zhou:1.Department of Galactophore Surgery, The First People's Hospital of Foshan, Foshan 528000, China. ;
期刊:Adipose Mesenchymal Stem Cell-Derived Exosomes Enhance PC12 Cell Function through the Activation of the PI3K/AKT Pathway
影响因子 :4.3
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Acupuncture Ameliorates Neuronal Cell Death, Inflammation, and Ferroptosis and Downregulated miR-23a-3p After Intracerebral Hemorrhage in Rats (2001-01-20)
作者:Ying Kong:1.First Ward of Acupuncture and Moxibustion Department, Second Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, 150001, China. ; Shulin Li:1.Second Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, 150001, China. ; Miao Zhang:1.Eighth Department of Acupuncture, Second Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, 150001, China. ; Wenting Xu:1.Second Ward of Rehabilitation Department, Second Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, 150001, China. ; Qiuxin Chen:1.Third Ward of Acupuncture and Moxibustion Department, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, 150040, China. ; Lihong Zheng:1.Department of Gastroenterology, Second Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, 150001, China. ; Peng Liu:1.Third Ward of Acupuncture and Moxibustion Department, First Affiliated Hospital, Heilongjiang Univers
期刊:Acupuncture Ameliorates Neuronal Cell Death, Inflammation, and Ferroptosis and Downregulated miR-23a-3p After Intracerebral Hemorrhage in Rats
DOI:10.1007/s12031-020-01770-x
影响因子 :3.1
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Four new resorcinol derivatives with neuroprotective activities from Xylaria nigripes (2003-01-20)
作者:Lan-Qing Li:1.College of Chemistry & Materials Science, South-Central University for Nationalities, Wuhan, China. ; Jing Li:1.Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, PR China. ; Hong-Ping Long:1.The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, PR China. ; Ji-Kai Liu:1.School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, PR China. ; Xian Wang:1.College of Chemistry & Materials Science, South-Central University for Nationalities, Wuhan, China. ;
期刊:Four new resorcinol derivatives with neuroprotective activities from Xylaria nigripes
DOI:10.1080/14786419.2021.1897591
影响因子 :2.2
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microRNA-184 enhances the sensitivity of pheochromocytoma-12 cells to doxorubicin by targeting ADAM22 (2002-01-20)
作者:Nairui Zhao: 1.Second Department of Endocrinology, Cangzhou Central Hospital, 16 **nhua West Road, Cangzhou, 061001, Hebei, China; Na Su: 1.Second Department of Endocrinology, Cangzhou Central Hospital, 16 **nhua West Road, Cangzhou, 061001, Hebei, China; Guangya Wang: 1.Second Department of Endocrinology, Cangzhou Central Hospital, 16 **nhua West Road, Cangzhou, 061001, Hebei, China; Dongxia Fu: 1.Second Department of Endocrinology, Cangzhou Central Hospital, 16 **nhua West Road, Cangzhou, 061001, Hebei, China; Fang Gao: 1.Second Department of Endocrinology, Cangzhou Central Hospital, 16 **nhua West Road, Cangzhou, 061001, Hebei, China; Yunna Zhang: 1.Second Department of Endocrinology, Cangzhou Central Hospital, 16 **nhua West Road, Cangzhou, 061001, Hebei, China;
期刊:microRNA-184 enhances the sensitivity of pheochromocytoma-12 cells to doxorubicin by targeting ADAM22
DOI:10.1007/s13273-021-00116-x
影响因子 :1.7
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A value-added application of eugenol as acaricidal agent: The mechanism of action and the safety evaluation (2012-00-20)
作者:Xiao-Fei Shang:1.Key Laboratory of New Animal Drug Project, Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, PR China. ; 2.School of Pharmacy, Lanzhou University, Lanzhou 730000, P.R. China. ; Li-Xia Dai:1.Key Laboratory of New Animal Drug Project, Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development of Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, PR China. ; Chen-Jie Yang:1.School of Pharmacy, Lanzhou University, Lanzhou 730000, P.R. China. ; Xiao Guo:1.Tibetan Medicine Research Center, Qinghai University, Xining 810016, P.R. China. ; Ying-Qian Liu:1.School of Pharmacy, Lanzhou University, Lanzhou 730000, P.R. China. ; Xiao-Lou Miao:1.Key Laboratory of New Animal Drug Project, Gansu Province, Key La
期刊:A value-added application of eugenol as acaricidal agent: The mechanism of action and the safety evaluation
DOI:10.1016/j.jare.2020.12.010
影响因子 :10.7
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Low-glucose-sensitive TRPC6 dysfunction drives hypoglycemia-induced cognitive impairment in diabetes (2010-00-20)
作者:Chengkang He:1.Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Chongqing Institute of Hypertension, Army Medical University, Chongqing, China. ; Peng Gao:1.Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Chongqing Institute of Hypertension, Army Medical University, Chongqing, China. ; Yuanting Cui:1.Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Chongqing Institute of Hypertension, Army Medical University, Chongqing, China. ; Qiang Li:1.Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Chongqing Institute of Hypertension, Army Medical University, Chongqing, China. ; Yingsha Li:1.Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Chongqing Institute of Hypertension, Army Medica
期刊:Low-glucose-sensitive TRPC6 dysfunction drives hypoglycemia-induced cognitive impairment in diabetes
DOI:10.1002/ctm2.205
影响因子 :10.6
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Neuroprotective Function of a Novel Hexapeptide QMDDQ from Shrimp via Activation of the PKA/CREB/BNDF Signaling Pathway and Its Structure–Activity Relationship (2006-00-20)
作者:Dan Wu:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. ; 2.College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, P.R. China. ; Shuyu Zhang:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. ; Na Sun:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. ; Beiwei Zhu:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. ; Songyi Lin:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. ;
期刊:Neuroprotective Function of a Novel Hexapeptide QMDDQ from Shrimp via Activation of the PKA/CREB/BNDF Signaling Pathway and Its Structure–Activity Relationship
影响因子 :6.1
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Optimal route of gold nanoclusters administration in mice targeting Parkinson’s disease (2002-00-20)
作者:Jinqi Hu:1.School of Chemistry, Chemical Engineering & Life Science, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan, 430070, PR China. ; Guanbin Gao:1.State Key Laboratory of Advanced Technology for Materials Synthesis & Processing, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan, 430070, PR China. ; Meng He:1.School of Chemistry, Chemical Engineering & Life Science, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan, 430070, PR China. ; Qiang Yin:1.School of Chemistry, Chemical Engineering & Life Science, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan, 430070, PR China. ; Xiaobing Gao:1.General Hospital of Central Theater Command, No. 627 Wuluo Road, Wuhan, 430070, PR China. ; Haixing Xu:1.School of Chemistry, Chemical Engineering & Life Science, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan, 430070, PR China. ; Taolei Sun:1.School of Chemistry, Chemical Engineering & Life Science, Wuhan University of Technology, No. 122 Lu
期刊:Optimal route of gold nanoclusters administration in mice targeting Parkinson’s disease
影响因子 :5.5
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Evaluation and structure–activity relationship analysis of antioxidant shrimp peptides (2008-09-20)
作者:Dan Wu:1.College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, P.R. China and National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. linsongyi730@163.com zhubeiwei@163.com. ; Na Sun:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. linsongyi730@163.com zhubeiwei@163.com. ; Jie Ding:1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. linsongyi730@163.com zhubeiwei@163.com. ; BeiWei Zhu:1.College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, P.R. China and National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, P.R. China. linsongyi730@163.com zhubeiwei@163.
期刊:Evaluation and structure–activity relationship analysis of antioxidant shrimp peptides
影响因子 :6.1
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Egg yolk phosphatidylcholine: Extraction, purification and its potential neuroprotective effect on PC12 cells (2003-09-20)
作者:Jin Chen: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; Songyi Lin: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; Na Sun: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; Zhijie Bao: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; Jiaying Shen: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; Xueqi Lu: 1.National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China;
期刊:Egg yolk phosphatidylcholine: Extraction, purification and its potential neuroprotective effect on PC12 cells
影响因子 :5.6
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Glutamine Improves Oxidative Stress through the Wnt3a/ β-Catenin Signaling Pathway in Alzheimers Disease In Vitro and In Vivo (2004-09-20)
作者:Yuan Wang:1.College of Acumoxibustion and Massage, Shaanxi University of Chinese Medicine, Xianyang 712046, China. ; 2.Shaanxi Key Laboratory of Acupuncture and Medicine, Xianyang 712046, China. ; Qiang Wang:1.College of Acumoxibustion and Massage, Shaanxi University of Chinese Medicine, Xianyang 712046, China. ; 2.Shaanxi Key Laboratory of Acupuncture and Medicine, Xianyang 712046, China. ; Jie Li:1.College of Acumoxibustion and Massage, Shaanxi University of Chinese Medicine, Xianyang 712046, China. ; 2.Shaanxi Key Laboratory of Acupuncture and Medicine, Xianyang 712046, China. ; Gang Lu:1.College of Acumoxibustion and Massage, Shaanxi University of Chinese Medicine, Xianyang 712046, China. ; 2.Shaanxi Key Laboratory of Acupuncture and Medicine, Xianyang 712046, China. ; Zhibin Liu:1.College of Acumoxibustion and Massage, Shaanxi University of Chinese Medicine, Xianyang 712046, China. ; 2.Shaanxi Key Laboratory of Acupuncture and Medicine, Xianyang 712046, China. ;
期刊:Glutamine Improves Oxidative Stress through the Wnt3a/ β-Catenin Signaling Pathway in Alzheimers Disease In Vitro and In Vivo
影响因子 :3.2
引用产品: PC-12 (Undifferentiated) 细胞 , RPMI-1640 (不含L-谷氨酰胺) 培养基
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Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells (2002-09-20)
作者:Pan Meng:1.Institute of Innovation and Applied Research in Chinese Medicine. ; Qing Zhu:1.Institute of Innovation and Applied Research in Chinese Medicine. ; 2.The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China. ; Hui Yang:1.The First Affiliated Hospital, Hunan University of Chinese Medicine. ; Dan Liu:1.The First Affiliated Hospital, Hunan University of Chinese Medicine. ; Xiaoyuan Lin:1.The First Affiliated Hospital, Hunan University of Chinese Medicine. ; Jian Liu:1.The First Affiliated Hospital, Hunan University of Chinese Medicine. ; Jingying Fan:1.Institute of Innovation and Applied Research in Chinese Medicine. ; Xiaodan Liu:1.Institute of Innovation and Applied Research in Chinese Medicine. ; Wei Su:1.Institute of Innovation and Applied Research in Chinese Medicine. ; Lin Liu:1.The First Affiliated Hospital, Hunan University of Chinese Medicine. ; Yuhong Wang:1.Institute of Innovation and
期刊:Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells
DOI:10.1097/WNR.0000000000001180
影响因子 :1.7
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