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产品概述
名称 | RSC96 (大鼠雪旺细胞) (种属鉴定正确) |
别称 | RSC 96; RSC-96 |
种属 | 大鼠 |
生长特性 | 贴壁细胞 |
细胞形态 | 神经细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | RSC96细胞是原代培养的大鼠雪旺细胞经长时间培养后自发转化而成的。2002年12月提交到ATCC的RSC96细胞污染了支原体,RSC96细胞后代细胞通过BM细胞周期蛋白处理21天消除支原体。处理后6周,用Hoechst染色、PCR和标准培养测试进行支原体检测,结果都呈阴性。 |
组织来源 | 雪旺细胞 |
细胞类型 | 自发永生化细胞 |
生物安全等级 | BSL-1 |
受体表达情况 | Nerve growth factor receptor (Ngfr); Protein and mRNA, negative;Platelet derived growth factor receptor, alpha; negative;Platelet derived growth factor receptor, beta; negative |
保藏机构 | ATCC; CRL-2765 |
种属鉴定
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种属鉴定图
参考文献
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Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson’s disease autonomic dysfunction (2024-01-26)
作者:Yangxia Li:1.Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ; Qing Tong:1.Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ; Ye Wang:1.Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ; Yue Cheng:1.Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ; Yao Geng:1.Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ; Tian Tian:1.Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing, China. ; Yongsheng Yuan:1.Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ; Yi Fan:1.Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing, China. yfan@njmu.edu.cn. ; Ming Lu:1.Jiangs
期刊:Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson’s disease autonomic dysfunction
DOI:10.1038/s41420-024-01824-8
影响因子 :7.0
引用产品: RSC96 细胞 , DMEM高糖 培养基
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Acetyl-11-keto-beta-boswellic acid modulates macrophage polarization and Schwann cell migration to accelerate spinal cord injury repair in rats (2024-03-02)
作者:Yao Wang:1.Department of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Zongliang Xiong:1.Department of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Yuncong Qiao:1.School of Life Sciences, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Qiyuan Zhang:1.Department of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Guanghu Zhou:1.Department of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Chong Zhou:1.Department of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Xianglin Ma:1.Department of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Xiaowen Jiang:1.Department of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China. ; Wenhui Yu:1.Department of Veterinary Medicine, Northeast Agricultural Univers
期刊:Acetyl-11-keto-beta-boswellic acid modulates macrophage polarization and Schwann cell migration to accelerate spinal cord injury repair in rats
影响因子 :5.5
引用产品: RAW 264.7 细胞 , RSC96 细胞
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Endothelial cell-derived exosomes boost and maintain repair-related phenotypes of Schwann cells via miR199-5p to promote nerve regeneration (2023-01-09)
作者:Jinsheng Huang:1.Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. ; Geyi Zhang:1.Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. ; Senrui Li:1.Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. ; Jiangnan Li:1.Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. ; Wengang Wang:1.Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. ; Jiajia Xue:1.State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, China. ; Yuanyi Wang:1.Department of Spinal Surger
期刊:Endothelial cell-derived exosomes boost and maintain repair-related phenotypes of Schwann cells via miR199-5p to promote nerve regeneration
DOI:10.1186/s12951-023-01767-9
影响因子 :10.2
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Endogenous Electric Field-Coupled PD@BP Biomimetic Periosteum Promotes Bone Regeneration through Sensory Nerve via Fanconi Anemia Signaling Pathway (2023-01-18)
作者:Yanlin Su:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China. ; Lian Zeng:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China. ; Rongli Deng:1.PCFM Lab, School of Chemistry and School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, Guangdong, 510000, China. ; Bing Ye:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China. ; Shuo Tang:1.Department of Orthopedics, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, 510127, China. ; Zekang Xiong:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China. ; Tingfang Sun:1.Department of Orthopedics, Union Hospital, Tongji Medical Col
期刊:Endogenous Electric Field-Coupled PD@BP Biomimetic Periosteum Promotes Bone Regeneration through Sensory Nerve via Fanconi Anemia Signaling Pathway
影响因子 :10.0
引用产品: RSC96 细胞
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Honokiol attenuates high glucose-induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC-1ɑ pathway in Schwann cells (2023-08-14)
作者:Man Hu:1.National & Local Joint Engineering Research Center of High-throughput Drug Screening Technology, Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, China. ; Wen Jiang:1.National & Local Joint Engineering Research Center of High-throughput Drug Screening Technology, Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, China. ; Chen Ye:1.National & Local Joint Engineering Research Center of High-throughput Drug Screening Technology, Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, China. ; Ting Hu:1.National & Local Joint Engineering Research Center of High-throug
期刊:Honokiol attenuates high glucose-induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC-1ɑ pathway in Schwann cells
DOI:10.1002/ptr.7984
影响因子 :7.2
引用产品: RSC96 细胞
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Cisplatin causes erectile dysfunction by decreasing endothelial and smooth muscle content and inducing cavernosal nerve senescence in rats (2023-01-25)
作者:Yinghao Yin:1.Department of Urology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China. ; 2.Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China. ; Yihong Zhou:1.Department of Urology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China. ; 2.Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China. ; Jun Zhou:1.Department of Urology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China. ; 2.Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China. ; Liangyu Zhao:1.Department of Urology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China. ; 2.Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospi
期刊:Cisplatin causes erectile dysfunction by decreasing endothelial and smooth muscle content and inducing cavernosal nerve senescence in rats
DOI:10.3389/fendo.2023.1096723
影响因子 :5.2
引用产品: RSC96 细胞
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Evodiamine attenuates oxidative stress and ferroptosis by inhibiting the MAPK signaling to improve bortezomib-induced peripheral neurotoxicity (2023-11-27)
作者:Yunlong Tang:1.Department of Hematology, Affiliated Hospital 6 of Nantong University, Yancheng Third People's Hospital, Yancheng, Jiangsu, China. ; Weiying Gu:1.Department of Hematology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China. ; Lingling Cheng:1.Department of Oncology, Yancheng Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Yancheng, Jiangsu, China. ;
期刊:Evodiamine attenuates oxidative stress and ferroptosis by inhibiting the MAPK signaling to improve bortezomib-induced peripheral neurotoxicity
影响因子 :4.5
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Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model (2023-05-06)
作者:Luchen Yang:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Zhengju Ren:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; 2.Department of Urology, the Second affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China. ; Pan Song:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Zhenghuan Liu:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Zhufeng Peng:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Jing Zhou:1.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. ; Qiang Dong:1.Department of Urology, Institute of
期刊:Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model
DOI:10.1007/s11064-023-03946-4
影响因子 :4.4
引用产品: PC-12 (Undifferentiated) 细胞 , RSC96 细胞
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Aptamer engineering exosomes loaded on biomimetic periosteum to promote angiogenesis and bone regeneration by targeting injured nerves via JNK3 MAPK pathway (2022-09-20)
作者:Yanlin Su:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China. ; Qing Gao:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China. ; Rongli Deng:1.PCFM Lab, School of Chemistry and School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, Guangdong 510000, China. ; Lian Zeng:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China. ; Jingyi Guo:1.College of Arts and Science of Hubei Normal University, Huangshi, Hubei 430022, China. ; Bing Ye:1.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China. ; Jialin Yu:1.The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei 430022, China. ; Xiaodong Guo:1.De
期刊:Aptamer engineering exosomes loaded on biomimetic periosteum to promote angiogenesis and bone regeneration by targeting injured nerves via JNK3 MAPK pathway
DOI:10.1016/j.mtbio.2022.100434
影响因子 :10.8
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