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产品概述
| 名称 | HPAF-II (人胰腺癌细胞) (STR鉴定正确) |
| 别称 | HPAF II; HPAFII; HPAF-2; HPAF2; HPAF/CD18; CD18/HPAF; HPAF-II/CD18; CD-18; CD18; CD 18 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | HPAF-II is a human pancreatic adenocarcinoma cell line derived from peritoneal ascitic fluid of a 44 year old Caucasian male with primary pancreatic adenocarcinoma and metastases to the liver, diaphragm and lymph nodes. |
| 年龄（性别） | 男性；44岁 |
| 组织来源 | 胰腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胰腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | 26 hours (PubMed=2734279); 70 hours (PubMed=25984343) |
| 保藏机构 | ATCC; CRL-1997 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10,11 D2S1338 16,19 D3S1358 14,18 D5S818 11,13 D7S820 10,13 D8S1179 11,12 D13S317 12 D16S539 11,13 D18S51 13 D19S433 12 D21S11 30,31 FGA 21,24 PentaD 9,13 PentaE 10,13 TH01 9 TPOX 8 vWA 17 D6S1043 12 D12S391 17 D2S441 11,14 -
STR鉴定图
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参考文献
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Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes (2024-01-25)
作者：Mao-Lin Li:1.School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, Guangdong 510006, China. ; Le-Tian Dai:1.School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, Guangdong 510006, China. ; Zhuo-Yu Gao:1.School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, Guangdong 510006, China. ; Jia-Tong Yan:1.School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, Guangdong 510006, China. ; Shu-Min Xu:1.School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, Guangdong 510006, China. ; Jia-Heng Tan:1.School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory
期刊：Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes
DOI：10.1021/acs.jmedchem.3c01773
影响因子 ：7.3
引用产品： MIA PaCa-2 细胞 , DMEM高糖 培养基 , 293 [HEK-293] 细胞 , HPAF-II 细胞 , U-87 MG 细胞 , MEM (ATCC改良) 培养基 , PANC-1 细胞 , HCT 116 细胞 , HFL1 细胞
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Novel PORCN inhibitor WHN-88 targets Wnt/β-catenin pathway and prevents the growth of Wnt-driven cancers (2023-02-28)
作者：Qihong Yang:1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China; University of Chinese Academy of Sciences, Beijing, 100049, China. ; Tong Qin:1.State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China. ; Tao An:1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China; School of Pharmaceutical Sciences, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, China. ; Hongna Wu:1.State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China. ; Gang Xu:1.Key Laboratory of Me
期刊：Novel PORCN inhibitor WHN-88 targets Wnt/β-catenin pathway and prevents the growth of Wnt-driven cancers
DOI：10.1016/j.ejphar.2023.175628
影响因子 ：5.0
引用产品： AsPC-1 细胞 , HPAF-II 细胞 , PA-1 细胞 , NCCIT 细胞
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