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产品概述
| 名称 | BPH-1 (人前列腺增生细胞) (STR鉴定正确) |
| 别称 | BPH1; Benign Prostatic Hyperplasia-1 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:5 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | prostate epithelial cells from a 68-year-old man with benign prostate hyperplasia; cells were immortalized with SV-40 large T-antigen; cells were described in the literature to express cytokeratins 8, 18, and 19 (but not 14) and to metabolize prostatic androgens. |
| 年龄（性别） | 男性；68岁 |
| 组织来源 | 前列腺 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~50 hours (DSMZ=ACC-143) |
| 保藏机构 | DSMZ; ACC-143 |
STR鉴定
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STR位点信息
Amelogenin X, Y CSF1PO 10,12 D2S1338 17 D3S1358 16 D5S818 11,12 D7S820 10,11 D8S1179 10,15 D13S317 11,12 D16S539 9 D18S51 10,16 D19S433 12.1,15 D21S11 28,32.2 FGA 21,24 PentaD 14 PentaE 7,10 TH01 6,7 TPOX 8,12 vWA 17 D6S1043 11,12 D12S391 22 D2S441 14 -
STR鉴定图
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参考文献
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Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate (2024-03-09)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05048-3
影响因子 ：7.4
引用产品： BPH-1 细胞
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Y-27632 targeting ROCK1&2 modulates cell growth, fibrosis and epithelial-mesenchymal transition in hyperplastic prostate by inhibiting β-catenin pathway (2024-10-26)
期刊：Molecular Biomedicine
DOI：10.1186/s43556-024-00216-9
影响因子 ：6.3
引用产品： BPH-1 细胞
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Epigenetic-related Gene-based Prognostic Model Construction and Validation in Prostate Adenocarcinoma (2024-05-08)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e30941
影响因子 ：4.0
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Identification of RBM15 as a prognostic biomarker in prostate cancer involving the regulation of prognostic m6A-related lncRNAs (2024-08-08)
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-024-02000-5
影响因子 ：2.8
引用产品： BPH-1 细胞 , C4-2 细胞 , PC-3 细胞 , RWPE-1 细胞 , DU 145 细胞 , LNCaP clone FGC 细胞 , 22RV1 细胞
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ARPC1A correlates with poor prognosis in prostate cancer and is up-regulated by glutamine metabolism to promote tumor cell migration, invasion and cytoskeletal changes (2023-02-22)
期刊：Cell and Bioscience
DOI：10.1186/s13578-023-00985-w
影响因子 ：7.5
引用产品： BPH-1 细胞
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Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles (2023-10-20)
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-023-00734-2
影响因子 ：5.7
引用产品： BPH-1 细胞
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STEAP4 modulates cell proliferation and oxidative stress in benign prostatic hyperplasia (2023-10-20)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110933
影响因子 ：4.8
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Changes in the Expression and Functional Activities of C-X-C Motif Chemokine Ligand 13 (CXCL13) in Hyperplastic Prostate (2022-12-21)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：6.2
引用产品： BPH-1 细胞
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