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产品概述
| 名称 | A-673 (人横纹肌肉瘤细胞) (STR鉴定正确) |
| 别称 | A673; RMS 1598; RMS1598 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 多边形 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | A-673细胞是一株源自15岁女性的横纹肌肉瘤的细胞株。A-673细胞在软琼脂上可形成克隆，亦能在免疫抑制血清处理的小鼠中成瘤。A-673细胞有四个以上的标志染色体，一个额外的F染色体和两个异常的B染色体。 |
| 年龄（性别） | 女性；15岁 |
| 组织来源 | 肌肉；横纹肌肉瘤 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肉瘤细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~28 hours |
| 致瘤性 | Yes, in immunosuppressed mice. |
| 保藏机构 | ATCC; CRL-1598 ATCC; CRL-7910ECACC; 85111504 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 16,21 D3S1358 14 D5S818 11,12 D7S820 10,12 D8S1179 11,13 D13S317 8,13 D16S539 11 D18S51 13,16 D19S433 13,14 D21S11 29,30.2 FGA 19,20 PentaD 12,13 PentaE 10,13 TH01 9.3 TPOX 8 vWA 15,18 D6S1043 11,12 D12S391 19,21 D2S441 14,15 -
STR鉴定图
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参考文献
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Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing’s sarcoma (2023-03-28)
作者：Xiangwen Shi:1.Kunming Medical University, Kunming, China. ; 2.Laboratory of Yunnan Traumatology and Orthopedics Clinical Medical Center, Yunnan Orthopedics and Sports Rehabilitation Clinical Medical Research Center, Department of Orthopedic Surgery, 920th Hospital of Joint Logistics Support Force of PLA, Kunming, China. ; Yipeng Wu:1.Kunming Medical University, Kunming, China. ; 2.Laboratory of Yunnan Traumatology and Orthopedics Clinical Medical Center, Yunnan Orthopedics and Sports Rehabilitation Clinical Medical Research Center, Department of Orthopedic Surgery, 920th Hospital of Joint Logistics Support Force of PLA, Kunming, China. ; Linmeng Tang:1.Bone and Joint Imaging Center, Department of Medical Imaging and Radiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China. ; Haonan Ni:1.Kunming Medical University, Kunming, China. ; Yongqing Xu:1.Laboratory of Yunnan Traumatology and Orthopedics Clinical Medical Center, Yunnan Orthopedics and Sports Re
期刊：Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing’s sarcoma
影响因子 ：5.2
引用产品： RD-ES 细胞 , A-673 细胞
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Integrative analyses of bulk microarray data to discover genes, pathways, and immune infiltration characteristics associated with targeting of Ewing sarcoma (2023-02-27)
作者：Binjie Cao:1.Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China. ; 2.Jiangsu Key Laboratory of Experimental and, Translational Non-Coding RNA Research, Yangzhou, China. ; Haijian Sun:1.Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ; Zhehao Fan:1.Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China. ; 2.Jiangsu Key Laboratory of Experimental and, Translational Non-Coding RNA Research, Yangzhou, China. ; Muhammad Babar Khawar:1.Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China. ; 2.Jiangsu Key Laboratory of Experimental and, Translational Non-Coding RNA Research, Yangzhou, China. ; 3.Applied Molecular Biology and Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan. ; Liangliang Cai:1.Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China. ;
期刊：Integrative analyses of bulk microarray data to discover genes, pathways, and immune infiltration characteristics associated with targeting of Ewing sarcoma
DOI：10.1007/s00432-023-04642-0
影响因子 ：3.6
引用产品： A-673 细胞
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Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma (2022-12-07)
作者：Zhao Zhang:1.Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, China. ; Yubo Shi:1.Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, China. ; Zhijie Zhu:1.Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, China. ; Jun Fu:1.Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, China. ; Dong Liu:1.Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, China. ; Xincheng Liu:1.Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, China. ; Jingyi Dang:1.Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, China. ; Huiren Tao:1.Department of Orthopaedics, Shenzhen University General Hospital, Shenzhen, China. ; Hongbin Fan:1.Department of Orthopaedic Surge
期刊：Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma
影响因子 ：6.5
引用产品： A-673 细胞
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TIPE1 inhibits the growth of Ewing’s sarcoma cells by suppressing Wnt/β-catenin signaling (2022-12-10)
作者：Zhichao Wang:1.Department of Orthopedics, Dalian Medical University, Dalian, 116044, China. ; 2.Department of Orthopedics, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, 225300, China. ; Libin Sun:1.Department of Orthopedics, Dalian Medical University, Dalian, 116044, China. ; 2.Department of Orthopedics, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, 225300, China. ; Shuaiyin Liu:1.Department of Orthopedics, Dalian Medical University, Dalian, 116044, China. ; 2.Department of Orthopedics, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, 225300, China. ; Haitao Jiang:1.Department of Orthopedics, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, 225300, China. bowenrain35@163.com. ;
期刊：TIPE1 inhibits the growth of Ewing’s sarcoma cells by suppressing Wnt/β-catenin signaling
DOI：10.1007/s12094-022-03030-3
影响因子 ：3.3
引用产品： A-673 细胞
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![293 [HEK-293] (人胚肾细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0001-1-1.jpg)
