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产品概述
名称 | 786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确) |
别称 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:6 |
推荐换液频率 | 2-3次/周 |
背景描述 | 786-O [786-0]细胞源自一个原发性透明细胞癌;786-O [786-0]细胞有微绒毛和桥粒,能在软琼脂内生长。786-O [786-0]细胞生成的一个PTH样的多肽与乳癌和肺癌中的肽相似。这个多肽的N端与PTH相似,活性与PTH相似,分子量为6000道尔顿。 |
年龄(性别) | 男性;58岁 |
组织来源 | 肾;肾细胞腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肾癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~24-45 hours |
致瘤性 | Yes, in immunosuppressed hamsters. |
保藏机构 | ATCC; CRL-1932 BCRC; 60243 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10 D2S1338 17,18 D3S1358 16 D5S818 9 D7S820 11,12 D8S1179 13 D13S317 8 D16S539 12 D18S51 13,14 D19S433 14,15 D21S11 29,30 FGA 24 PentaD 9,12 PentaE 7,16 TH01 6,9.3 TPOX 8,11 vWA 15,17 D6S1043 11 D12S391 17,18 D2S441 10,11 -
STR鉴定图
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参考文献
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Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells (2024-03-30)
期刊:APOPTOSIS
DOI:10.1007/s10495-024-01953-6
影响因子 :7.2
引用产品: HK-2 细胞 , Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , SW839 细胞
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Selective expansion of renal cancer stem cells using microfluidic single-cell culture arrays for anticancer drug testing (2024-02-01)
期刊:LAB ON A CHIP
影响因子 :6.1
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , ACHN 细胞
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Identification of molecular subtypes and diagnostic model in clear cell renal cell carcinoma based on collagen-related genes may predict the response of immunotherapy (2024-02-05)
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2024.1325447
影响因子 :5.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma (2024-02-08)
期刊:Aging-US
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , ACHN 细胞 , HK-2 细胞
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Design, synthesis and biological evaluation of rhein–piperazine–furanone hybrids as potential anticancer agents (2024-02-13)
期刊:RSC Medicinal Chemistry
影响因子 :4.1
引用产品: A549 [A-549] 细胞 , NCI-H460 [H460] 细胞 , PC-9 细胞 , Calu-1 细胞 , SK-BR-3 [SKBR3] 细胞 , SK-OV-3 细胞 , 786-O [786-0] 细胞 , HuH-7 细胞 , HCT 116 细胞 , Hela 细胞 , WI-38 细胞 , MCF 10A 细胞 , KGN 细胞 , 293T [HEK-293T] 细胞 , DMEM高糖 培养基 , MEM 培养基 , DMEM/F12 培养基 , McCoy's 5A 培养基 , RPMI-1640 培养基 , 0.25%胰蛋白酶溶液 (含EDTA,溶于PBS)
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Disruption of Autophagic Flux and Treatment with the PDPK1 Inhibitor GSK2334470 Synergistically Inhibit Renal Cell Carcinoma Pathogenesis (2024-01-20)
期刊:Journal of Cancer
影响因子 :3.9
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC (2024-03-21)
期刊:GENE
DOI:10.1016/j.gene.2024.148403
影响因子 :3.5
引用产品: HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , Caki-1 细胞 , RPMI-1640 培养基 , MEM 培养基
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LINC00645 inhibits renal cell carcinoma progression by interacting with HNRNPA2B1 to regulate the ROCK1 mRNA stability (2024-02-01)
期刊:GENE
DOI:10.1016/j.gene.2024.148232
影响因子 :3.5
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , ACHN 细胞
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Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma (2023-03-02)
期刊:CANCER RESEARCH
DOI:10.1158/0008-5472.CAN-22-2224
影响因子 :11.2
引用产品: 786-O [786-0] 细胞 , Caki-2 细胞 , McCoy's 5A (含双抗) 培养基
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Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming (2023-02-20)
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-05677-4
影响因子 :9.0
引用产品: A-498 细胞 , ACHN 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞
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Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination (2023-11-01)
期刊:ONCOGENE
DOI:10.1038/s41388-023-02879-0
影响因子 :8.0
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 293T [HEK-293T] 细胞 , BEAS-2B 细胞 , McCoy's 5A 培养基
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The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis (2023-02-02)
期刊:ONCOGENE
DOI:10.1038/s41388-023-02613-w
影响因子 :8.0
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , STR鉴定 , MEM (含NEAA) 培养基
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Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma (2023-08-26)
期刊:Computational and Structural Biotechnology Journal
DOI:10.1016/j.csbj.2023.08.023
影响因子 :6.0
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma (2023-03-15)
期刊:American Journal of Cancer Research
DOI:PMID:37034217
影响因子 :5.3
引用产品: ACHN 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , 293T [HEK-293T] 细胞 , MEM 培养基 , RPMI-1640 培养基
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Establishing a prognostic model based on five starvation-related long non-coding RNAs for clear cell renal cell carcinoma (2023-06-20)
期刊:Aging-US
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , Caki-1 细胞 , HK-2 细胞
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LncRNA-encoded Micropeptide ACLY-BP drives lipid deposition and cell proliferation in Clear Cell Renal Cell Carcinoma via maintenance of ACLY acetylation (2023-07-06)
期刊:MOLECULAR CANCER RESEARCH
DOI:10.1158/1541-7786.MCR-22-0781
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , 293T [HEK-293T] 细胞 , ACHN 细胞 , Caki-1 细胞
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Netrin Family Genes as Prognostic Markers and Therapeutic Targets for Clear Cell Renal Cell Carcinoma: Netrin-4 Acts through the Wnt/β-Catenin Signaling Pathway (2023-05-18)
期刊:Cancers
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , 769-P 细胞
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Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function (2023-07-06)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , HK-2 细胞
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Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes (2023-06-08)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: 786-O [786-0] 细胞 , HK-2 细胞 , THP-1 细胞 , 特级胎牛血清
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A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance (2023-04-08)
期刊:Scientific Reports
DOI:10.1038/s41598-023-27975-9
影响因子 :4.6
引用产品: HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , Ham's F-12K 培养基 , 人前列腺上皮细胞完全培养基
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ROCK2-RNA interaction map reveals multiple biological mechanisms underlying tumor progression in renal cell carcinoma (2023-07-07)
期刊:Human Cell
DOI:10.1007/s13577-023-00947-x
影响因子 :4.3
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , Annexin V-FITC/ PI荧光双染细胞凋亡检测试剂盒
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GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling (2023-01-20)
期刊:ONCOLOGY REPORTS
影响因子 :4.2
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , McCoy's 5A 培养基
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Total Flavone Content of Cydonia oblonga Miller Inhibits Proliferation and Migration of Renal Carcinoma Cells by Inhibiting the S1PR2/FAK Pathway (2023-03-30)
期刊:JOURNAL OF FOOD BIOCHEMISTRY
影响因子 :4.0
引用产品: 786-O [786-0] 细胞 , Renca [RenCa] 细胞 , Renca [RenCa]细胞专用培养基
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway (2023-01-02)
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-022-01926-2
影响因子 :3.4
引用产品: OS-RC-2 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , 769-P 细胞 , Caki-1 细胞
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RUNX1 predicts poor prognosis and correlates with tumor progression in clear cell renal carcinoma (2023-10-12)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.8
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , 青霉素-链霉素溶液 (双抗),100×
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Downregulation of NEBL promotes migration and invasion of clear cell renal cell carcinoma by inducing epithelial-mesenchymal transition (2023-12-29)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.8
引用产品: 293T [HEK-293T] 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞
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TTC13 expression and STAT3 activation may form a positive feedback loop to promote ccRCC progression (2023-10-30)
期刊:PeerJ
影响因子 :2.7
引用产品: 786-O [786-0] 细胞 , Caki-1 细胞
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YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway (2022-08-17)
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-022-02460-9
影响因子 :12.7
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , STR鉴定 , MEM (含NEAA) 培养基
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The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors (2004-02-20)
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-04760-6
影响因子 :9.0
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , 293T [HEK-293T] 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , MEM (含NEAA) 培养基 , DMEM高糖 培养基
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Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis (2022-12-25)
期刊:Cancers
影响因子 :6.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , Caki-1 细胞 , 769-P 细胞 , HK-2 细胞
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Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis. (2022-09-21)
期刊:Frontiers in Pharmacology
影响因子 :6.0
引用产品: SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , Ham's F-12K 培养基 , DMEM高糖 培养基 , 人前列腺上皮细胞完全培养基 , RPMI-1640 培养基
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Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma (2022-08-09)
期刊:BMC CANCER
DOI:10.1186/s12885-022-09965-8
影响因子 :4.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma (2022-02-16)
期刊:Journal of Inflammation Research
影响因子 :4.5
引用产品: Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , HK-2 细胞
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AKG induces cell apoptosis by inducing reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing PI3K/AKT/mTOR-mediated autophagy in renal cell carcinoma (2022-09-16)
期刊:ENVIRONMENTAL TOXICOLOGY
影响因子 :4.1
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis (2022-09-01)
期刊:Translational Andrology and Urology
影响因子 :2.5
引用产品: A-498 细胞 , ACHN 细胞 , SN12C 细胞 , 786-O [786-0] 细胞 , 769-P 细胞
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression (2022-11-30)
期刊:TRANSPLANT IMMUNOLOGY
DOI:10.1016/j.trim.2022.101764
影响因子 :2.0
引用产品: HK-2 细胞 , OS-RC-2 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
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RRM2 Regulates Sensitivity to Sunitinib and PD-1 Blockade in Renal Cancer by Stabilizing ANXA1 and Activating the AKT Pathway (2007-01-20)
期刊:Advanced Science
影响因子 :15.1
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , Renca [RenCa] 细胞 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , MEM (含NEAA) 培养基 , Renca [RenCa]细胞专用培养基
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Hypoxia-induced microRNA-155 overexpression in extracellular vesicles promotes renal cell carcinoma progression by targeting FOXO3 (2003-01-20)
期刊:Aging-US
影响因子 :5.2
引用产品: 786-O [786-0] 细胞
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The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study (2011-01-20)
期刊:Cancer Medicine
影响因子 :4.0
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma (2002-01-20)
期刊:Cell Biology International
影响因子 :3.9
引用产品: HK-2 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞
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Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis (2001-01-20)
期刊:Journal Of Receptors And Signal Transduction
DOI:10.1080/10799893.2020.1870494
影响因子 :2.8
引用产品: Caki-2 细胞 , 786-O [786-0] 细胞
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APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells (2003-01-20)
期刊:IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI:10.1007/s11626-021-00589-z
影响因子 :2.1
引用产品: 293T [HEK-293T] 细胞 , 786-O [786-0] 细胞 , A-498 细胞
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Tumor promoting effects of circRNA_001287 on renal cell carcinoma through miR-144-targeted CEP55 (2012-00-20)
期刊:Journal Of Experimental & Clinical Cancer Research
DOI:10.1186/s13046-020-01744-2
影响因子 :11.3
引用产品: A-498 细胞 , Caki-1 细胞 , Caki-2 细胞 , 786-O [786-0] 细胞
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes (2001-00-20)
期刊:Cancer Medicine
影响因子 :4.0
引用产品: HK-2 细胞 , A-498 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
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Comprehensive analysis of the HOXA gene family identifes HOXA13as a novel oncogenic gene in kidney renal clear cell carcinoma (2005-00-20)
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-020-03259-x
影响因子 :3.6
引用产品: 786-O [786-0] 细胞 , Caki-1 细胞 , A-498 细胞 , HK-2 细胞
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LncRNA-LET inhibits cell growth of clear cell renal cell carcinoma by regulating miR-373-3p (2011-09-20)
期刊:Cancer Cell International
影响因子 :5.8
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , 769-P 细胞 , 293T [HEK-293T] 细胞 , Caki-1细胞专用培养基 , 786-O [786-0]细胞专用培养基 , 769-P细胞专用培养基 , 293T [HEK-293T]细胞专用培养基
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma (2005-09-20)
期刊:J Cancer
影响因子 :4.5
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma (2003-08-20)
期刊:Oncology Letters
影响因子 :2.9
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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