产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
名称 | K-562 [K562] (人慢性髓原白血病细胞) (STR鉴定正确) |
别称 | K562; K 562; GM05372 |
种属 | 人 |
生长特性 | 悬浮细胞 |
细胞形态 | 淋巴细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 3×10^5-5×10^5cells/mL |
推荐换液频率 | 2-3次/周 |
注意事项 | 该细胞为悬浮细胞,请注意离心收集细胞悬液;请勿直接倒掉细胞培养液。 |
背景描述 | 连续细胞株K-562是由Lozzio从一位临终的53岁女性慢性骨髓性白血病患者的胸水中建立。K-562细胞被归入高度未分化的粒性白细胞类,Erson等对其表面膜性质的研究表明,K-562细胞是一株人类红白血病细胞。K-562细胞在自然杀伤分析中广泛作为高敏感的体外受体,See Pross等将K-562细胞用于NK细胞的体外详细检测,包括NK细胞活性的数学量化。K-562母细胞是多能性造血恶性细胞,它能自发分化成可识别的红血球祖细胞、粒性白细胞、单核细胞等。K-562细胞是EBNA阴性的。 |
年龄(性别) | 女性;53岁 |
组织来源 | 骨髓;慢性骨髓性白血病(CML) |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 白血病细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~30-48 hours |
致瘤性 | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells). |
保藏机构 | ATCC; CCL-243 BCRC; 60007 BCRJ; 0126 CCLV; CCLV-RIE 0439 DSMZ; ACC-10 ECACC; 89121407 |
STR鉴定
-
STR位点信息
Amelogenin X CSF1PO 9,10 D2S1338 17 D3S1358 16 D5S818 11,12 D7S820 9,11 D8S1179 12 D13S317 8 D16S539 11,12 D18S51 15,16 D19S433 14,14.2 D21S11 29,31 FGA 21,24 PentaD 9,13 PentaE 5,14 TH01 9.3 TPOX 8,9 vWA 16 D6S1043 11 D12S391 23 D2S441 10,14 -
STR鉴定图
-
参考文献
-
A Divalent Chikungunya and Zika Nanovaccine with Thermostable Self-assembly Multivalent Scaffold LS-SUMO (2024-02-10)
期刊:Advanced Healthcare Materials
影响因子 :10.0
引用产品: K-562 [K562] 细胞 , IMDM 培养基
-
Pyrotinib and trastuzumab combination treatment synergistically overcomes HER2 dependency in HER2-positive breast cancer: insights from the PHILA trial (2024-10-03)
期刊:EBioMedicine
DOI:10.1016/j.ebiom.2024.105379
影响因子 :9.7
引用产品: SK-BR-3 [SKBR3] 细胞 , 人外周血单个核细胞完全培养基 , BT-474 [BT474] 细胞 , K-562 [K562] 细胞
-
PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis (2024-05-17)
期刊:eLife
影响因子 :6.4
引用产品: K-562 [K562] 细胞 , IMDM 培养基 , 青霉素-链霉素溶液(双抗),100×
-
Broadening anticancer spectrum by preprocessing and treatment of T- lymphocytes expressed FcγRI and monoclonal antibodies for refractory cancers (2024-06-17)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2024.1400177
影响因子 :5.7
引用产品: 293T [HEK-293T] 细胞 , SK-BR-3 [SKBR3] 细胞 , MCF 10A 细胞 , MDA-MB-231 细胞 , Jurkat76 细胞 , SK-OV-3 细胞 , K-562 [K562] 细胞 , MKN-45 细胞 , Daudi 细胞 , 人外周血单核细胞 , SGC-7901 细胞 , Raji 细胞 , HCT 116 细胞
-
Cytotoxic and Antibacterial Meroterpenoids Isolated from the Marine-Derived Fungus Talaromyces sp. M27416 (2024-04-20)
期刊:Marine Drugs
影响因子 :5.4
引用产品: K-562 [K562] 细胞 , TE-1 细胞 , HOS 细胞 , GBC-SD 细胞 , PaTu 8988t 细胞 , DU 145 细胞 , 293T [HEK-293T] 细胞 , SF126 细胞 , MCF7 [MCF-7] 细胞 , HCT 116 细胞 , Hela 细胞 , A549 [A-549] 细胞 , Hep G2 细胞 , A-375 细胞 , MKN-45 细胞 , 5637 细胞 , 786-O [786-0] 细胞 , CAL-62 细胞 , A-673 细胞 , HL-7702 [L-02; LO2] 细胞
-
METTL16 participates in haemoglobin H disease through m6A modification (2024-08-01)
期刊:PLoS One
DOI:10.1371/journal.pone.0306043
影响因子 :2.9
引用产品: K-562 [K562] 细胞
-
Selection of reference genes in liproxstatin-1-treated K562 Leukemia cells via RT-qPCR and RNA sequencing (2024-01-02)
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-023-08912-5
影响因子 :2.8
引用产品: K-562 [K562] 细胞
-
AZD8055 Is More Effective Than Rapamycin in Inhibiting Proliferation and Promoting Mitochondrial Clearance in Erythroid Differentiation (2024-10-08)
期刊:Analytical Cellular Pathology
影响因子 :2.6
引用产品: K-562 [K562] 细胞
-
Paclitaxel mediates the PI3K/AKT/mTOR pathway to reduce proliferation of FLT3‑ITD+ AML cells and promote apoptosis (2024-02-23)
期刊:Experimental and Therapeutic Medicine
影响因子 :2.4
引用产品: K-562 [K562] 细胞
-
pH-triggered dynamic erosive small molecule chlorambucil nano-prodrugs mediate robust oral chemotherapy (2023-07-25)
期刊:Asian Journal of Pharmaceutical Sciences
DOI:10.1016/j.ajps.2023.100832
影响因子 :10.2
引用产品: Hep G2 细胞 , H22 细胞 , MCF7 [MCF-7] 细胞 , K-562 [K562] 细胞 , A549 [A-549] 细胞
-
CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia (2023-07-07)
期刊:Asian Journal of Pharmaceutical Sciences
DOI:10.1016/j.ajps.2023.100826
影响因子 :10.2
引用产品: K-562 [K562] 细胞 , THP-1 细胞
-
Label-free, rapid and highly accurate identification and categorization of leukemia cells via Raman spectroscopy (2023-08-22)
期刊:SENSORS AND ACTUATORS B-CHEMICAL
影响因子 :8.4
引用产品: K-562 [K562] 细胞 , U-937 细胞 , Raji 细胞 , Jurkat, Clone E6-1 细胞 , K-562 [K562]细胞专用培养基 , U-937细胞专用培养基 , Raji细胞专用培养基 , Jurkat, Clone E6-1细胞专用培养基
-
Wedelolactone induces natural killer cell activity and the improvement to bioavailability using polysaccharides from Ligustri Lucidi Fructus (2023-06-05)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2023.125208
影响因子 :8.2
引用产品: NK-92MI 细胞 , K-562 [K562] 细胞 , NK-92MI细胞专用培养基
-
Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies (2023-05-13)
期刊:LIFE SCIENCES
影响因子 :6.1
引用产品: HL-60 细胞 , K-562 [K562] 细胞
-
Development and evaluation of novel artemisinin-isatin hybrids with potential anti-leukemic cytotoxicity (2023-04-14)
期刊:Frontiers in Oncology
影响因子 :4.7
-
Asperuloside regulates the proliferation, apoptosis, and differentiation of chronic myeloid leukemia cell line K562 through the RAS/MEK/ERK pathway (2023-12-16)
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e23580
影响因子 :4.0
引用产品: K-562 [K562] 细胞 , IMDM 培养基 , 青霉素-链霉素溶液(双抗),100× , 特级胎牛血清
-
Ester tethered artemisinin-isatin hybrids: design, synthesis and anti-leukemic activity evaluation (2023-08-21)
期刊:MEDICINAL CHEMISTRY RESEARCH
DOI:10.1007/s00044-023-03122-x
影响因子 :2.6
引用产品: K-562 [K562] 细胞 , K562/ADR 细胞 , CCRF-CEM [CCRF CEM] 细胞 , 人外周血单核细胞
-
Pentanoate-Tethered Artemisinin-Isatin Hybrids with Antileukemic Potential (2023-03-21)
期刊:ChemistrySelect
影响因子 :2.1
引用产品: K-562 [K562] 细胞 , K562/ADR 细胞 , CCRF-CEM [CCRF CEM] 细胞
-
Tet2-mediated DNA demethylation regulates the proliferation and apoptosis of human leukemia K562 cells (2023-03-31)
期刊:CELLULAR AND MOLECULAR BIOLOGY
影响因子 :1.6
引用产品: K-562 [K562] 细胞
-
Liproxstatin?1 induces cell cycle arrest, apoptosis, and caspase?3/GSDME?dependent secondary pyroptosis in K562 cells (2022-08-17)
期刊:INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 :5.9
引用产品: K-562 [K562] 细胞 , SH-SY5Y [SHSY-5Y] 细胞
-
Antitumor Activity and Mechanism of Action of the Antimicrobial Peptide AMP-17 on Human Leukemia K562 Cells (2022-11-21)
期刊:MOLECULES
影响因子 :4.9
引用产品: K-562 [K562] 细胞
-
Lipid droplets as endogenous intracellular microlenses (2021-12-06)
期刊:Light-Science & Applications
DOI:10.1038/s41377-021-00687-3
影响因子 :19.4
引用产品: K-562 [K562] 细胞
-
CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T?cells (2021-07-16)
期刊:Molecular Therapy-Oncolytics
DOI:10.1016/j.omto.2021.07.003
影响因子 :5.7
引用产品: A549/DDP 细胞 , COS-1 细胞 , K-562 [K562] 细胞 , NCI-H929 细胞
-
Detection of K562 Leukemia Cells in Different States Using a Graphene-SERS Platform (2021-09-15)
期刊:ACS Applied Nano Materials
影响因子 :5.1
引用产品: K-562 [K562] 细胞 , K-562 [K562]细胞专用培养基
-
Human m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease (2021-10-14)
期刊:Scientific Reports
DOI:10.1038/s41598-021-99867-9
影响因子 :4.6
引用产品: K-562 [K562] 细胞
-
A novel upregulated LncRNA-AC026150.8 promotes chemo-resistance and predicts poor prognosis in acute myeloid leukemia (2021-10-19)
期刊:Cancer Medicine
影响因子 :4.0
引用产品: KG-1 细胞 , K-562 [K562] 细胞
-
TXNRD1: A Key Regulator Involved in the Ferroptosis of CML Cells Induced by Cysteine Depletion In Vitro (2021-12-07)
期刊:Oxidative Medicine and Cellular Longevity
影响因子 :0.0
引用产品: K-562 [K562] 细胞 , K-562 [K562] 细胞
-
All-optical targeted drug delivery and real-time detection of a single cancer cell (2020-03-01)
期刊:Nanophotonics
影响因子 :7.5
引用产品: K-562 [K562] 细胞
-
Rational Engineering a Multichannel Upconversion Sensorfor Multiplex Detection of Matrix Metalloproteinases Activities (2018-07-17)
期刊:ACS Sensors
DOI:10.1021/acssensors.8b00320
影响因子 :8.9
引用产品: HT-1080 [HT1080] 细胞 , K-562 [K562] 细胞
FAQs
Q:{{item.question}}
A:
产品资料


识别码示意图