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产品概述
名称 | Caki-2 (人乳头状肾细胞癌细胞)(STR鉴定正确) |
别称 | CAKI-2; CaKi-2; caki-2; CAKI 2; Caki 2; Caki2; CAKI2 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | Caki-2细胞源自一位69岁白人男性的初期肾腺癌组织。 |
年龄(性别) | 男性;69岁 |
组织来源 | 肾脏 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肾癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~30-40 hours |
致瘤性 | Yes, in nude mice; forms clear cell carcinoma. |
抗原表达情况 | Blood Type A; Rh- |
保藏机构 | ATCC; HTB-47 DSMZ; ACC-54 ECACC; 93120819 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 17,20 D3S1358 14 D5S818 11 D7S820 12 D8S1179 10 D13S317 10 D16S539 9,13 D18S51 17 D19S433 13,14 D21S11 27,31 FGA 21,22 PentaD 10,13 PentaE 7,17 TH01 6 TPOX 9,11 vWA 16,17 D6S1043 11,17 D12S391 19,23 D2S441 14 -
STR鉴定图
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参考文献
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TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3 (2024-05-22)
期刊:Cell Death & Disease
DOI:10.1038/s41419-024-06741-3
影响因子 :9.0
引用产品: DMEM高糖 培养基 , McCoy's 5A 培养基 , MEM 培养基 , ACHN 细胞 , Caki-2 细胞 , RPMI-1640 培养基 , Caki-1 细胞 , 769-P 细胞
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USP7 depletion potentiates HIF2α degradation and inhibits clear cell renal cell carcinoma progression (2024-10-15)
期刊:Cell Death & Disease
DOI:10.1038/s41419-024-07136-0
影响因子 :8.1
引用产品: Caki-2 细胞 , A-498 细胞 , OS-RC-2 细胞 , 786-O [786-0] 细胞
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A multifunctional antibody fusion protein 57103 targeting CD24, IL-4R, and αvβ3 for treating cancer and regulating the tumor microenvironment (2024-05-17)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2024.116714
影响因子 :6.9
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , OS-RC-2 细胞 , Caki-2 细胞
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PER3 promoter hypermethylation correlates to the progression of pan-cancer (2024-10-14)
期刊:Clinical Epigenetics
DOI:10.1186/s13148-024-01760-5
影响因子 :4.8
引用产品: Caki-2 细胞 , HK-2 细胞 , 786-O [786-0] 细胞 , McCoy's 5A 培养基 , RPMI-1640 培养基 , A549 [A-549] 细胞 , 青霉素-链霉素溶液(双抗),100×
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Proteomics Analysis of Renal Cell Line Caki-2 with AFMID Overexpression and Potential Biomarker Discovery in Urine (2024-08-30)
期刊:JOURNAL OF PROTEOME RESEARCH
DOI:10.1021/acs.jproteome.4c00431
影响因子 :3.8
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Development and validation of a prognostic model based on m6A-related lncRNAs to predict prognosis for papillary renal cell cancer patients (2024-12-28)
期刊:Scientific Reports
DOI:10.1038/s41598-024-83263-0
影响因子 :3.8
引用产品: Caki-2 细胞
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Comprehensive molecular analyses and experimental validation of CDCAs with potential implications in kidney renal papillary cell carcinoma prognosis (2024-06-14)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e33045
影响因子 :3.4
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KAT7 Suppresses Tumorigenesis in Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating Cell Cycle and Ferroptosis Sensitivity (2024-07-02)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2024.114149
影响因子 :3.3
引用产品: ACHN 细胞 , Caki-1 细胞 , 786-O [786-0] 细胞 , Caki-2 细胞
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Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma (2024-11-29)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2024.117181
影响因子 :3.3
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , Caki-2 细胞 , HK-2 细胞 , 769-P 细胞
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Exploring necrosis-associated mitochondrial gene signatures: revealing their role in prognosis and immunotherapy of renal clear cell carcinoma (2024-07-18)
期刊:CLINICAL AND EXPERIMENTAL MEDICINE
DOI:10.1007/s10238-024-01426-9
影响因子 :3.2
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , ACHN 细胞 , Caki-1 细胞 , HK-2 细胞
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Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis (2024-05-11)
期刊:Discover Oncology
DOI:10.1007/s12672-024-01018-9
影响因子 :2.2
引用产品: A-498 细胞 , Caki-2 细胞 , Caki-1 细胞 , 769-P 细胞 , 293 [HEK-293] 细胞 , OS-RC-2 细胞 , 786-O [786-0] 细胞
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Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma (2023-03-02)
期刊:CANCER RESEARCH
DOI:10.1158/0008-5472.CAN-22-2224
影响因子 :11.2
引用产品: 786-O [786-0] 细胞 , Caki-2 细胞 , McCoy's 5A (含双抗) 培养基
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ARHGAP11A Is a Novel Prognostic and Predictive Biomarker Correlated with Immunosuppressive Microenvironment in Clear Cell Renal Cell Carcinoma (2023-04-24)
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.6
引用产品: Caki-2 细胞
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Identification of a novel 5-methylcytosine-related signature for prognostic prediction of kidney renal papillary cell carcinoma and a Putative target for drug repurposing (2023-07-29)
期刊:Translational Oncology
DOI:10.1016/j.tranon.2023.101741
影响因子 :5.0
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Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1 (2023-05-29)
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-023-04877-x
影响因子 :3.6
引用产品: HK-2 细胞 , Caki-1 细胞 , OS-RC-2 细胞
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Loss of ACOX1 in clear cell renal cell carcinoma and its correlation with clinical features (2023-09-08)
期刊:Open Life Sciences
影响因子 :2.2
引用产品: 293T [HEK-293T] 细胞 , 786-O [786-0] 细胞 , Caki-2 细胞
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Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma (2022-09-30)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2022.1021935
影响因子 :8.8
引用产品: ACHN 细胞 , HK-2 细胞 , Caki-2 细胞 , A-498 细胞 , Caki-1 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 769-P 细胞
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Long noncoding RNA-LINC00478 promotes the progression of clear cell renal cell carcinoma through PBX3 (2022-09-09)
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.6
引用产品: Caki-2 细胞
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Epigenetic inactivation of hydroxymethylglutaryl CoA synthase reduces ketogenesis and facilitates tumor cell motility in clear cell renal carcinoma (2021-09-20)
期刊:Pathology Research And Practice
影响因子 :3.3
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Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis (2021-01-20)
期刊:Journal Of Receptors And Signal Transduction
DOI:10.1080/10799893.2020.1870494
影响因子 :2.8
引用产品: Caki-2 细胞 , 786-O [786-0] 细胞
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Tumor promoting effects of circRNA_001287 on renal cell carcinoma through miR-144-targeted CEP55 (2020-12-01)
期刊:Journal Of Experimental & Clinical Cancer Research
DOI:10.1186/s13046-020-01744-2
影响因子 :11.3
引用产品: A-498 细胞 , Caki-1 细胞 , Caki-2 细胞 , 786-O [786-0] 细胞
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