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产品概述
| 名称 | Caki-2 (人乳头状肾细胞癌细胞)(STR鉴定正确) |
| 别称 | CAKI-2; CaKi-2; caki-2; CAKI 2; Caki 2; Caki2; CAKI2 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | Caki-2细胞源自一位69岁白人男性的初期肾腺癌组织。 |
| 年龄（性别） | 男性；69岁 |
| 组织来源 | 肾脏 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肾癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~30-40 hours |
| 致瘤性 | Yes, in nude mice; forms clear cell carcinoma. |
| 抗原表达情况 | Blood Type A; Rh- |
| 保藏机构 | ATCC; HTB-47 DSMZ; ACC-54 ECACC; 93120819 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 17,20 D3S1358 14 D5S818 11 D7S820 12 D8S1179 10 D13S317 10 D16S539 9,13 D18S51 17 D19S433 13,14 D21S11 27,31 FGA 21,22 PentaD 10,13 PentaE 7,17 TH01 6 TPOX 9,11 vWA 16,17 D6S1043 11,17 D12S391 19,23 D2S441 14 -
STR鉴定图
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参考文献
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Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma (2023-03-02)
作者：Zhenyuan Yu:1.Center for Genomic and Personalized Medicine, Guangxi key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, P.R. China. ; 2.Department of Urology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China. ; Yufang Lv:1.Center for Genomic and Personalized Medicine, Guangxi key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, P.R. China. ; 2.Department of Urology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China. ; Cheng Su:1.Center for Genomic and Personalized Medicine, Guangxi key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi
期刊：Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma
DOI：10.1158/0008-5472.CAN-22-2224
影响因子 ：11.2
引用产品： 786-O [786-0] 细胞 , Caki-2 细胞 , McCoy's 5A (含双抗) 培养基
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ARHGAP11A Is a Novel Prognostic and Predictive Biomarker Correlated with Immunosuppressive Microenvironment in Clear Cell Renal Cell Carcinoma (2023-04-24)
作者：Huihui Yang:1.Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing100069, China. ; Hongning Zhang:1.Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing100069, China. ; Liuxu Zhang:1.Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing100069, China. ; Paizigul Tusuphan:1.Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing100069, China. ; Junfang Zheng:1.Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing100069
期刊：ARHGAP11A Is a Novel Prognostic and Predictive Biomarker Correlated with Immunosuppressive Microenvironment in Clear Cell Renal Cell Carcinoma
影响因子 ：5.6
引用产品： Caki-2 细胞
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Identification of a novel 5-methylcytosine-related signature for prognostic prediction of kidney renal papillary cell carcinoma and a Putative target for drug repurposing (2023-07-29)
作者：Zhen Zhang:1.Department of Anesthesiology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China. Electronic address: zlyyzhangzhen2130@zzu.edu.cn. ; Chunhua Cao:1.Department of Oncology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China; Institute of Oncology, Hubei University of Arts and Science, Xiangyang 441021, China. ; Chun-Li Zhou:1.Department of Anesthesiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China. ; Xilong Li:1.Department of Anesthesiology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China. ; Changhong Miao:1.Department of Anesthesiology, Cancer Hospital of Fudan University, Shanghai 200032, China. ; Li Shen:1.Department of Biomedical Engineering, Hong Kong Polytechnic University, Hong Kong SAR, China. ; Rajeev K Singla:1.Joint Labo
期刊：Identification of a novel 5-methylcytosine-related signature for prognostic prediction of kidney renal papillary cell carcinoma and a Putative target for drug repurposing
DOI：10.1016/j.tranon.2023.101741
影响因子 ：5.0
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Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1 (2023-05-29)
作者：Lin Yang:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. ; Jiahao Liu:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. ; Sheng Li:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. ; Xiaoqiang Liu:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. ; Fuchun Zheng:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. ; Songhui Xu:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. ; Bin Fu:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. urofbin@163.com. ; Jing Xiong:1.Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. alex7023@126.com. ;
期刊：Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1
DOI：10.1007/s00432-023-04877-x
影响因子 ：3.6
引用产品： HK-2 细胞 , Caki-1 细胞 , OS-RC-2 细胞
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Long noncoding RNA-LINC00478 promotes the progression of clear cell renal cell carcinoma through PBX3 (2022-09-09)
作者：Zhiling Tang:1.Department of Urology Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China. ; Chenye Tang:1.Department of Urology Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China. ; Chun Sun:1.Department of Urology Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China. ; Xiangjun Ying:1.Department of Urology Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China. ; Ruilin Shen:1.Department of Urology Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China. ;
期刊：Long noncoding RNA-LINC00478 promotes the progression of clear cell renal cell carcinoma through PBX3
影响因子 ：3.6
引用产品： Caki-2 细胞
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Epigenetic inactivation of hydroxymethylglutaryl CoA synthase reduces ketogenesis and facilitates tumor cell motility in clear cell renal carcinoma (2009-01-20)
作者：Peipei Han:1.Key Laboratory of High-Incidence-Tumor Prevention & Treatment (Guangxi Medical University), Ministry of Education, Nanning, China; Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, China. ; Yifang Wang:1.Life Science Institute, Guangxi Medical University, Nanning, China. ; Wenqi Luo:1.Department of Pathology, Guangxi Medical University Cancer Hospital, Nanning, China. ; Yunliang Lu:1.Key Laboratory of High-Incidence-Tumor Prevention & Treatment (Guangxi Medical University), Ministry of Education, Nanning, China. ; Xiaohui Zhou:1.Life Science Institute, Guangxi Medical University, Nanning, China. ; Yanping Yang:1.Key Laboratory of High-Incidence-Tumor Prevention & Treatment (Guangxi Medical University), Ministry of Education, Nanning, China. ; Qian Zheng:1.Life Science Institute, Guangxi Medical University, Nanning, China. ; Danping Li:1.Key Laboratory of High-Incidence-Tumor Prevention & Treatment (Guangxi Medical University)
期刊：Epigenetic inactivation of hydroxymethylglutaryl CoA synthase reduces ketogenesis and facilitates tumor cell motility in clear cell renal carcinoma
影响因子 ：3.3
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Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis (2001-01-20)
作者：Fanchang Zeng:1.Department of Urology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Hainan, P.R. China. ; Liumei Luo:1.Division of Science and Education, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Hainan, P.R. China. ; Mi Song:1.Department of Urology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Hainan, P.R. China. ; Daoyuan Li:1.Department of Urology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Hainan, P.R. China. ;
期刊：Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis
DOI：10.1080/10799893.2020.1870494
影响因子 ：2.8
引用产品： Caki-2 细胞 , 786-O [786-0] 细胞
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Tumor promoting effects of circRNA_001287 on renal cell carcinoma through miR-144-targeted CEP55 (2012-00-20)
作者：Jiafu Feng:1.Department of Clinical Laboratory, Mianyang Central Hospital, No. 12, Changjia Lane, Jingzhong Street, Fucheng District, Sichuan Province, 621000, Mianyang, PR China. jiafufeng@aliyun.com. ; Yongcan Guo:1.Clinical Laboratory of Traditional, Chinese Medicine Hospital Affiliated to Southwest Medical University, 646000, Luzhou, Province, PR China. ; Yuanmeng Li:1.Department of Medical Laboratory, Affiliated Hospital of Southwest Medical University, Sichuan Province, 646000, Luzhou, PR China. ; Jiawei Zeng:1.Department of Clinical Laboratory, Mianyang Central Hospital, No. 12, Changjia Lane, Jingzhong Street, Fucheng District, Sichuan Province, 621000, Mianyang, PR China. ; Yaodong Wang:1.Department of Urology Surgery, Mianyang Central Hospital, Sichuan Province, 621000, Mianyang, PR China. ; Yuwei Yang:1.Department of Clinical Laboratory, Mianyang Central Hospital, No. 12, Changjia Lane, Jingzhong Street, Fucheng District, Sichuan Province, 621000, Mianyang, PR China. ;
期刊：Tumor promoting effects of circRNA_001287 on renal cell carcinoma through miR-144-targeted CEP55
DOI：10.1186/s13046-020-01744-2
影响因子 ：11.3
引用产品： A-498 细胞 , Caki-1 细胞 , Caki-2 细胞 , 786-O [786-0] 细胞
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