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产品概述
名称 | OS-RC-2 (人肾癌细胞) (STR鉴定正确) |
别称 | RC-2 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | OS-RC-2细胞来源于日本人的肾脏肿瘤细胞;OS-RC-2细胞移植到裸鼠可成瘤。 |
年龄(性别) | 男性;52岁 |
组织来源 | 肾 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肾癌细胞 |
倍增时间 | ~60-72 hours |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 12,13 D2S1338 20 D3S1358 17 D5S818 11,12 D7S820 10,11 D8S1179 14 D13S317 8,12 D16S539 11 D18S51 14 D19S433 13,14 D21S11 31.2 FGA 24 PentaD 11 PentaE 11,17 TH01 6 TPOX 8,11 vWA 16 D6S1043 12 D12S391 20,23 D2S441 11 -
STR鉴定图
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参考文献
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HIF-2α/LPCAT1 orchestrates the reprogramming of lipid metabolism in ccRCC by modulating the FBXW7-mediated ubiquitination of ACLY (2025-01-01)
期刊:International Journal of Biological Sciences
影响因子 :8.2
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , ACHN 细胞 , Caki-1 细胞 , HK-2 细胞 , 293T [HEK-293T] 细胞
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Hypoxia-triggered ERRα acetylation enhanced its oncogenic role and promoted progression of renal cell carcinoma by coordinating autophagosome-lysosome fusion (2025-01-16)
期刊:Cell Death & Disease
DOI:10.1038/s41419-025-07345-1
影响因子 :8.1
引用产品: HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 293T [HEK-293T] 细胞
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Atractylenolide I inhibits angiogenesis and reverses sunitinib resistance in clear cell renal cell carcinoma through ATP6V0D2-mediated autophagic degradation of EPAS1/HIF2α (2024-11-04)
期刊:Autophagy
DOI:10.1080/15548627.2024.2421699
影响因子 :14.6
引用产品: OS-RC-2 细胞
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USP7 depletion potentiates HIF2α degradation and inhibits clear cell renal cell carcinoma progression (2024-10-15)
期刊:Cell Death & Disease
DOI:10.1038/s41419-024-07136-0
影响因子 :8.1
引用产品: Caki-2 细胞 , A-498 细胞 , OS-RC-2 细胞 , 786-O [786-0] 细胞
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A multifunctional antibody fusion protein 57103 targeting CD24, IL-4R, and αvβ3 for treating cancer and regulating the tumor microenvironment (2024-05-17)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2024.116714
影响因子 :6.9
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , OS-RC-2 细胞 , Caki-2 细胞
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TRIM26 inhibits clear cell renal cell carcinoma progression through destabilizing ETK and thus inactivation of AKT/mTOR signaling (2024-05-21)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-024-05273-w
影响因子 :6.1
引用产品: Caki-1 细胞 , OS-RC-2 细胞
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Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma (2024-02-08)
期刊:Aging-US
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , ACHN 细胞 , HK-2 细胞
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Bioinformatics analysis and experimental verification of the cancer-promoting effect of DHODH in clear cell renal cell carcinoma (2024-05-25)
期刊:Scientific Reports
DOI:10.1038/s41598-024-62738-0
影响因子 :4.6
引用产品: 786-O [786-0] 细胞 , RPMI-1640 培养基 , OS-RC-2 细胞
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Improved Immunotherapy Outcomes via Cuproptosis Upregulation of HLA-DRA Expression: Promoting the Aggregation of CD4+ and CD8+T Lymphocytes in Clear Cell Renal Cell Carcinoma (2024-05-24)
期刊:Pharmaceuticals
影响因子 :4.3
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , HK-2 细胞 , Renca [RenCa] 细胞
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SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment (2024-05-16)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2024.116975
影响因子 :3.8
引用产品: 786-O [786-0] 细胞 , SW839 细胞 , A-498 细胞 , HK-2 细胞 , OS-RC-2 细胞 , THP-1 细胞
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Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC (2024-03-21)
期刊:GENE
DOI:10.1016/j.gene.2024.148403
影响因子 :3.5
引用产品: HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , Caki-1 细胞 , RPMI-1640 培养基 , MEM 培养基
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AGBL2 promotes renal cell carcinoma cells proliferation and migration via α-tubulin detyrosination (2024-09-04)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e37086
影响因子 :3.4
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , 293T [HEK-293T] 细胞
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Exploring necrosis-associated mitochondrial gene signatures: revealing their role in prognosis and immunotherapy of renal clear cell carcinoma (2024-07-18)
期刊:CLINICAL AND EXPERIMENTAL MEDICINE
DOI:10.1007/s10238-024-01426-9
影响因子 :3.2
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , ACHN 细胞 , Caki-1 细胞 , HK-2 细胞
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ETS homologous factor, controlled by lysine-specific demethylase 5B, suppresses clear cell renal cell carcinoma by inducing Filamin-B (2024-06-14)
期刊:GENE
DOI:10.1016/j.gene.2024.148702
影响因子 :2.6
引用产品: OS-RC-2 细胞 , Caki-1 细胞 , HK-2 细胞 , THP-1 细胞
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Comprehensive Pan-Cancer Analysis of Connexin 43 as a Potential Biomarker and Therapeutic Target in Human Kidney Renal Clear Cell Carcinoma (KIRC) (2024-05-08)
期刊:Medicina-Lithuania
影响因子 :2.6
引用产品: ACHN 细胞 , OS-RC-2 细胞 , HK-2 细胞 , 786-O [786-0] 细胞
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METTL3 and IGF2BP1-mediated m6A modification of ZHX2 promotes tumor property of renal cell carcinoma (2024-08-19)
期刊:KIDNEY & BLOOD PRESSURE RESEARCH
影响因子 :2.3
引用产品: RPMI-1640 完全培养基(含10% FBS) , 786-O [786-0] 细胞 , OS-RC-2 细胞 , HK-2 细胞 , 特级胎牛血清 , MEM(含NEAA) 培养基 , ACHN 细胞
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Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis (2024-05-11)
期刊:Discover Oncology
DOI:10.1007/s12672-024-01018-9
影响因子 :2.2
引用产品: A-498 细胞 , Caki-2 细胞 , Caki-1 细胞 , 769-P 细胞 , 293 [HEK-293] 细胞 , OS-RC-2 细胞 , 786-O [786-0] 细胞
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Integrative bioinformatics and in vitro exploration of EVI2A expression: unraveling its immunological and prognostic implications in kidney renal clear cell carcinoma (2024-10-16)
期刊:ONCOLOGY RESEARCH
影响因子 :2.0
引用产品: Caki-1 细胞 , OS-RC-2 细胞 , ACHN 细胞 , HK-2 细胞 , 786-O [786-0] 细胞
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Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination (2023-11-01)
期刊:ONCOGENE
DOI:10.1038/s41388-023-02879-0
影响因子 :8.0
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 293T [HEK-293T] 细胞 , BEAS-2B 细胞 , McCoy's 5A 培养基
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HOXD8 suppresses renal cell carcinoma growth by upregulating SHMT1 expression (2023-09-26)
期刊:CANCER SCIENCE
影响因子 :5.7
引用产品: OS-RC-2 细胞 , ACHN 细胞
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Root extract of Hemsleya amabilis Diels suppresses renal cell carcinoma cell growth through inducing apoptosis and G2/M phase arrest via PI3K/AKT signaling pathway activation (2023-08-07)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
引用产品: McCoy's 5A完全培养基 (含10%FBS) , MEM完全培养基 (含NEAA、10%FBS) , OS-RC-2 细胞 , ACHN 细胞
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Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1 (2023-05-29)
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-023-04877-x
影响因子 :3.6
引用产品: HK-2 细胞 , Caki-1 细胞 , OS-RC-2 细胞
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Construction and Validation of a Novel Cuproptosis-Related Seven-lncRNA Signature to Predict the Outcomes, Immunotherapeutic Responses, and Targeted Therapy in Patients with Clear Cell Renal Cell Carcinoma (2023-01-25)
期刊:DISEASE MARKERS
影响因子 :3.5
引用产品: A-498 细胞 , OS-RC-2 细胞
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway (2023-01-02)
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-022-01926-2
影响因子 :3.4
引用产品: OS-RC-2 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , 769-P 细胞 , Caki-1 细胞
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Downregulation of NEBL promotes migration and invasion of clear cell renal cell carcinoma by inducing epithelial-mesenchymal transition (2023-12-29)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.8
引用产品: 293T [HEK-293T] 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞
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Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma (2022-09-30)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2022.1021935
影响因子 :8.8
引用产品: ACHN 细胞 , HK-2 细胞 , Caki-2 细胞 , A-498 细胞 , Caki-1 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 769-P 细胞
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Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma (2022-01-14)
期刊:Faseb Journal
影响因子 :4.8
引用产品: OS-RC-2 细胞 , Caki-1 细胞
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression (2022-11-30)
期刊:TRANSPLANT IMMUNOLOGY
DOI:10.1016/j.trim.2022.101764
影响因子 :2.0
引用产品: HK-2 细胞 , OS-RC-2 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
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