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产品概述
名称 | 769-P (人肾细胞腺癌细胞) (STR鉴定正确) |
别称 | 769P; 769-p |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:8 |
推荐换液频率 | 2-3次/周 |
背景描述 | 769-P细胞来源于原发性透明细胞腺癌;769-P细胞呈边界不清楚的球形、高核质比、有微绒毛和桥粒;769-P细胞可以在软琼脂中生长。 |
年龄(性别) | 女性;63岁 |
组织来源 | 器官:肾;疾病:肾透明细胞腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肾癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~35 hours |
致瘤性 | Yes, forms colonies in soft agar.Yes, forms tumors in immunosuppressed hamsters.Yes, forms tumors in nude mice. |
保藏机构 | ATCC; CRL-1933 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 18 D3S1358 16 D5S818 12 D7S820 10,11 D8S1179 12,16 D13S317 10,14 D16S539 9,13 D18S51 14,17 D19S433 14,15 D21S11 28,30 FGA 20,22 PentaD 12,16 PentaE 7,18 TH01 6,9.3 TPOX 8,11 vWA 18 D6S1043 11,14 D12S391 18 D2S441 11,14 -
STR鉴定图
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参考文献
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Hypoxia-triggered ERRα acetylation enhanced its oncogenic role and promoted progression of renal cell carcinoma by coordinating autophagosome-lysosome fusion (2025-01-16)
期刊:Cell Death & Disease
DOI:10.1038/s41419-025-07345-1
影响因子 :8.1
引用产品: HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 293T [HEK-293T] 细胞
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TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3 (2024-05-22)
期刊:Cell Death & Disease
DOI:10.1038/s41419-024-06741-3
影响因子 :9.0
引用产品: DMEM高糖 培养基 , McCoy's 5A 培养基 , MEM 培养基 , ACHN 细胞 , Caki-2 细胞 , RPMI-1640 培养基 , Caki-1 细胞 , 769-P 细胞
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Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells (2024-03-30)
期刊:APOPTOSIS
DOI:10.1007/s10495-024-01953-6
影响因子 :7.2
引用产品: HK-2 细胞 , Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , SW839 细胞
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CLIP170 enhancing FOSL1 expression via attenuating ubiquitin-mediated degradation of β-catenin drives renal cell carcinoma progression (2024-11-28)
期刊:CELLULAR AND MOLECULAR LIFE SCIENCES
DOI:10.1007/s00018-024-05504-9
影响因子 :6.2
引用产品: 786-O [786-0] 细胞 , Caki-1 细胞 , 769-P 细胞 , HK-2 细胞 , ACHN 细胞
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Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma (2024-08-10)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2024.112737
影响因子 :4.8
引用产品: 786-O [786-0] 细胞 , 769-P 细胞
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Decoding Sunitinib Resistance in ccRCC: Metabolic reprogramming induced ABAT and GABAergic system shifts (2024-06-28)
期刊:iScience
DOI:10.1016/j.isci.2024.110415
影响因子 :4.6
引用产品: HUV-EC-C [HUVEC] 细胞 , STR鉴定 , 769-P 细胞 , 786-O [786-0] 细胞
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Low ACADM expression predicts poor prognosis and suppressive tumor microenvironment in clear cell renal cell carcinoma (2024-04-25)
期刊:Scientific Reports
DOI:10.1038/s41598-024-59746-5
影响因子 :4.6
引用产品: RPMI-1640 培养基 , 786-O [786-0] 细胞 , ACHN 细胞 , 769-P 细胞 , HK-2 细胞 , Caki-1 细胞 , McCoy's 5A 培养基 , MEM(含NEAA) 培养基
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LINC00645 inhibits renal cell carcinoma progression by interacting with HNRNPA2B1 to regulate the ROCK1 mRNA stability (2024-02-01)
期刊:GENE
DOI:10.1016/j.gene.2024.148232
影响因子 :3.5
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , ACHN 细胞
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ZBP1 as a prognostic biomarker correlated with cell proliferation in clear cell renal cell carcinoma (2024-10-10)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e39267
影响因子 :3.4
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞 , ACHN 细胞 , 769-P 细胞
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Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma (2024-11-29)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2024.117181
影响因子 :3.3
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , Caki-2 细胞 , HK-2 细胞 , 769-P 细胞
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A novel cancer-associated fibroblast signature for kidney renal clear cell carcinoma via integrated analysis of single-cell and bulk RNA-sequencing (2024-07-26)
期刊:Discover Oncology
DOI:10.1007/s12672-024-01175-x
影响因子 :2.8
引用产品: 769-P 细胞 , 786-O [786-0] 细胞
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Comprehensive analysis of signaling lymphocyte activation molecule family as a prognostic biomarker and correlation with immune infiltration in clear cell renal cell carcinoma (2024-06-03)
期刊:Oncology Letters
影响因子 :2.5
引用产品: 786-O [786-0] 细胞 , 769-P 细胞
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PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway (2024-06-27)
期刊:PeerJ
影响因子 :2.3
引用产品: Caki-1 细胞 , ACHN 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , 293 [HEK-293] 细胞
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Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis (2024-05-11)
期刊:Discover Oncology
DOI:10.1007/s12672-024-01018-9
影响因子 :2.2
引用产品: A-498 细胞 , Caki-2 细胞 , Caki-1 细胞 , 769-P 细胞 , 293 [HEK-293] 细胞 , OS-RC-2 细胞 , 786-O [786-0] 细胞
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Exploring Novel Genome Instability-associated lncRNAs and their Potential Function in Pan-Renal Cell Carcinoma (2024-08-01)
期刊:COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
DOI:10.2174/0113862073258779231020052115
影响因子 :1.6
引用产品: 786-O [786-0] 细胞 , 769-P 细胞
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CircSCNN1A inhibits the proliferation, migration and invasion of renal cell carcinoma cells by decreasing CLDN8 expression through miR-590-5p (2024-05-19)
期刊:GENESIS
影响因子 :1.5
引用产品: 786-O [786-0] 细胞 , McCoy's 5A 培养基 , DMEM高糖 培养基 , A-498 细胞 , HK-2 细胞 , RPMI-1640 培养基 , 769-P 细胞 , Caki-1 细胞
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The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma (2023-05-12)
期刊:CELL DEATH AND DIFFERENTIATION
DOI:10.1038/s41418-023-01176-3
影响因子 :12.4
引用产品: 769-P 细胞
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma (2023-03-15)
期刊:American Journal of Cancer Research
DOI:PMID:37034217
影响因子 :5.3
引用产品: ACHN 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , 293T [HEK-293T] 细胞 , MEM 培养基 , RPMI-1640 培养基
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Netrin Family Genes as Prognostic Markers and Therapeutic Targets for Clear Cell Renal Cell Carcinoma: Netrin-4 Acts through the Wnt/β-Catenin Signaling Pathway (2023-05-18)
期刊:Cancers
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , 769-P 细胞
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Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function (2023-07-06)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , HK-2 细胞
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The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma (2023-08-29)
期刊:Human Cell
DOI:10.1007/s13577-023-00973-9
影响因子 :4.3
引用产品: HK-2 细胞 , 769-P 细胞 , McCoy's 5A 培养基
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ROCK2-RNA interaction map reveals multiple biological mechanisms underlying tumor progression in renal cell carcinoma (2023-07-07)
期刊:Human Cell
DOI:10.1007/s13577-023-00947-x
影响因子 :4.3
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , Annexin V-FITC/ PI荧光双染细胞凋亡检测试剂盒
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway (2023-01-02)
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-022-01926-2
影响因子 :3.4
引用产品: OS-RC-2 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , 769-P 细胞 , Caki-1 细胞
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A Novel Tumor Mutation Burden Related lncRNA Signature Identified Prognosis and Tumor Immune Microenvironment Features in Clear Cell Renal Cell Carcinoma (2023-07-01)
期刊:COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
DOI:10.2174/1386207325666220926123923
影响因子 :1.8
引用产品: HK-2 细胞 , 786-O [786-0] 细胞 , 769-P 细胞 , ACHN 细胞 , Ham's F-12K 培养基
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Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma (2022-09-30)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2022.1021935
影响因子 :8.8
引用产品: ACHN 细胞 , HK-2 细胞 , Caki-2 细胞 , A-498 细胞 , Caki-1 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 769-P 细胞
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Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis (2022-12-25)
期刊:Cancers
影响因子 :6.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , Caki-1 细胞 , 769-P 细胞 , HK-2 细胞
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Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma (2022-02-16)
期刊:Journal of Inflammation Research
影响因子 :4.5
引用产品: Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , HK-2 细胞
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Upregulation of Metallothionein 1?G (MT1G) Negatively Regulates Ferroptosis in Clear Cell Renal Cell Carcinoma by Reducing Glutathione Consumption (2022-09-27)
期刊:Journal of Oncology
影响因子 :4.5
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis (2022-09-01)
期刊:Translational Andrology and Urology
影响因子 :2.5
引用产品: A-498 细胞 , ACHN 细胞 , SN12C 细胞 , 786-O [786-0] 细胞 , 769-P 细胞
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Deubiquitylation and stabilization of ARMC5 by ubiquitin-specific processing protease 7 (USP7) are critical for RCC proliferation (2021-02-05)
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 :5.3
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , A-498 细胞 , ACHN 细胞 , 293T [HEK-293T] 细胞
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TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT (2020-03-04)
期刊:Journal of Cancer
影响因子 :3.9
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LncRNA-LET inhibits cell growth of clear cell renal cell carcinoma by regulating miR-373-3p (2019-11-21)
期刊:Cancer Cell International
影响因子 :5.8
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , 769-P 细胞 , 293T [HEK-293T] 细胞 , Caki-1细胞专用培养基 , 786-O [786-0]细胞专用培养基 , 769-P细胞专用培养基 , 293T [HEK-293T]细胞专用培养基
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