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产品概述
名称 | ACHN (人肾细胞腺癌细胞) (STR鉴定正确) |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | 人干扰素可抑制ACHN细胞生长;ACHN细胞能用于人干扰素、干扰素诱导因子的抗肿瘤活性研究。 |
年龄(性别) | 男性;22岁 |
组织来源 | 肾细胞腺癌,胸水转移灶 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肾癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~28-36 hours |
致瘤性 | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells). |
保藏机构 | ATCC; CRL-1611 ECACC; 88100508 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11 D2S1338 17 D3S1358 17 D5S818 12 D7S820 9,11 D8S1179 12 D13S317 12 D16S539 12,13 D18S51 16 D19S433 14,15 D21S11 30 FGA 22 PentaD 12 PentaE 16 TH01 8 TPOX 8,11 vWA 16,17 D6S1043 11 D12S391 19,22 D2S441 11,14 -
STR鉴定图
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参考文献
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Selective expansion of renal cancer stem cells using microfluidic single-cell culture arrays for anticancer drug testing (2024-02-01)
期刊:LAB ON A CHIP
影响因子 :6.1
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , ACHN 细胞
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Identification of molecular subtypes and diagnostic model in clear cell renal cell carcinoma based on collagen-related genes may predict the response of immunotherapy (2024-02-05)
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2024.1325447
影响因子 :5.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma (2024-02-08)
期刊:Aging-US
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , ACHN 细胞 , HK-2 细胞
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Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC (2024-03-21)
期刊:GENE
DOI:10.1016/j.gene.2024.148403
影响因子 :3.5
引用产品: HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , Caki-1 细胞 , RPMI-1640 培养基 , MEM 培养基
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LINC00645 inhibits renal cell carcinoma progression by interacting with HNRNPA2B1 to regulate the ROCK1 mRNA stability (2024-02-01)
期刊:GENE
DOI:10.1016/j.gene.2024.148232
影响因子 :3.5
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , ACHN 细胞
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Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming (2023-02-20)
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-05677-4
影响因子 :9.0
引用产品: A-498 细胞 , ACHN 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞
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Prognostic and tumor microenvironmental feature of clear cell renal cell carcinoma revealed by m6A and lactylation modification-related genes (2023-08-11)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1225023
影响因子 :7.3
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HOXD8 suppresses renal cell carcinoma growth by upregulating SHMT1 expression (2023-09-26)
期刊:CANCER SCIENCE
影响因子 :5.7
引用产品: OS-RC-2 细胞 , ACHN 细胞
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High-fat diet alters immune cells in spleen, kidney and tumor and impacts the volume growth of renal cell carcinoma (2023-10-18)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.110982
影响因子 :5.6
引用产品: ACHN 细胞
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Root extract of Hemsleya amabilis Diels suppresses renal cell carcinoma cell growth through inducing apoptosis and G2/M phase arrest via PI3K/AKT signaling pathway activation (2023-08-07)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
引用产品: McCoy's 5A完全培养基 (含10%FBS) , MEM完全培养基 (含NEAA、10%FBS) , OS-RC-2 细胞 , ACHN 细胞
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma (2023-03-15)
期刊:American Journal of Cancer Research
DOI:PMID:37034217
影响因子 :5.3
引用产品: ACHN 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , 293T [HEK-293T] 细胞 , MEM 培养基 , RPMI-1640 培养基
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LncRNA-encoded Micropeptide ACLY-BP drives lipid deposition and cell proliferation in Clear Cell Renal Cell Carcinoma via maintenance of ACLY acetylation (2023-07-06)
期刊:MOLECULAR CANCER RESEARCH
DOI:10.1158/1541-7786.MCR-22-0781
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , 293T [HEK-293T] 细胞 , ACHN 细胞 , Caki-1 细胞
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GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling (2023-01-20)
期刊:ONCOLOGY REPORTS
影响因子 :4.2
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , McCoy's 5A 培养基
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway (2023-01-02)
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-022-01926-2
影响因子 :3.4
引用产品: OS-RC-2 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , 769-P 细胞 , Caki-1 细胞
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Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer (2022-11-17)
期刊:BRITISH JOURNAL OF CANCER
DOI:10.1038/s41416-022-02058-0
影响因子 :9.1
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The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors (2004-02-20)
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-04760-6
影响因子 :9.0
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , 293T [HEK-293T] 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , MEM (含NEAA) 培养基 , DMEM高糖 培养基
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Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis (2022-12-25)
期刊:Cancers
影响因子 :6.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , Caki-1 细胞 , 769-P 细胞 , HK-2 细胞
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Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma (2022-08-09)
期刊:BMC CANCER
DOI:10.1186/s12885-022-09965-8
影响因子 :4.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma (2022-02-16)
期刊:Journal of Inflammation Research
影响因子 :4.5
引用产品: Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , HK-2 细胞
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The potential of Lycium barbarum miR166a in kidney cancer treatment (2022-12-28)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2022.113455
影响因子 :4.1
引用产品: Caki-1 细胞 , ACHN 细胞 , McCoy's 5A 培养基 , DMEM高糖 培养基
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AKG induces cell apoptosis by inducing reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing PI3K/AKT/mTOR-mediated autophagy in renal cell carcinoma (2022-09-16)
期刊:ENVIRONMENTAL TOXICOLOGY
影响因子 :4.1
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis (2022-09-01)
期刊:Translational Andrology and Urology
影响因子 :2.5
引用产品: A-498 细胞 , ACHN 细胞 , SN12C 细胞 , 786-O [786-0] 细胞 , 769-P 细胞
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression (2022-11-30)
期刊:TRANSPLANT IMMUNOLOGY
DOI:10.1016/j.trim.2022.101764
影响因子 :2.0
引用产品: HK-2 细胞 , OS-RC-2 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
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Pachymic Acid Inhibits the Migration and Epithelial–Mesenchymal Transition of Renal Cell Carcinoma (2022-10-17)
期刊:Natural Product Communications
影响因子 :1.5
引用产品: ACHN 细胞 , ACHN细胞专用培养基
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RETRACTED ARTICLE: Silencing circular RNA-ZNF652 represses proliferation and EMT process of renal carcinoma cells via raising miR-205 (2002-00-20)
期刊:Artificial Cells Nanomedicine and Biotechnology
DOI:10.1080/21691401.2020.1725532
影响因子 :5.8
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes (2001-00-20)
期刊:Cancer Medicine
影响因子 :4.0
引用产品: HK-2 细胞 , A-498 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
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TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT (2003-00-20)
期刊:Journal of Cancer
影响因子 :3.9
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma (2005-09-20)
期刊:J Cancer
影响因子 :4.5
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma (2003-08-20)
期刊:Oncology Letters
影响因子 :2.9
引用产品: 786-O [786-0] 细胞 , ACHN 细胞
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