产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
名称 | PLC/PRF/5 (人肝癌亚力山大细胞) (STR鉴定正确) |
别称 | PLC-PRF-5; PLC PRF 5; PLC/PRF5; PLCPRF5; PLC-8024; PLC8024; PLC; Alexander cells; Alexander; Primary Liver Carcinoma/Poliomyelitis Research Foundation/5 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | PLC/PRF/5细胞分泌乙肝病毒表面抗原(HBsAg);PLC/PRF/5细胞原先被支原体污染,后用BM-cycline去除支原体。 |
组织来源 | 肝癌;亚力山大细胞 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肝胆癌细胞 |
生物安全等级 | BSL-2 [Cells contain hepatitis B] |
倍增时间 | ~36-48 hours |
基因表达情况 | hepatitis virus B surface antigen (HBsAg) |
保藏机构 | ATCC; CRL-8024 ECACC; 85061113 |
STR鉴定
-
STR位点信息
Amelogenin X CSF1PO 10 D2S1338 19,22 D3S1358 15 D5S818 12 D7S820 9,11 D8S1179 13,16 D13S317 11,12 D16S539 13 D18S51 17 D19S433 11,13 D21S11 30,33.2 FGA 19.2,25 PentaD 6,10 PentaE 10,16 TH01 8 TPOX 8 vWA 15,16 D6S1043 13,21 D12S391 15,20 D2S441 12,14 -
STR鉴定图
-
参考文献
-
The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine (2024-06-12)
期刊:CELL DEATH AND DIFFERENTIATION
DOI:10.1038/s41418-024-01323-4
影响因子 :13.7
引用产品: Hep G2 细胞 , B16 细胞 , PLC/PRF/5 细胞
-
GPR56 facilitates hepatocellular carcinoma metastasis by promoting the TGF-β signaling pathway (2024-10-01)
期刊:Cell Death & Disease
DOI:10.1038/s41419-024-07095-6
影响因子 :8.1
引用产品: PLC/PRF/5 细胞 , 特级胎牛血清
-
RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling (2024-02-18)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-024-04964-8
影响因子 :7.4
引用产品: Hep 3B2.1-7 细胞 , HuH-7 细胞 , PLC/PRF/5 细胞 , Li-7 细胞 , THLE-2 细胞
-
Design, synthesis, and antitumor activities of novel ureido/thioureido derivatives with a 4-phenylthiazol-2-amine scaffold (2024-07-02)
期刊:Journal of Saudi Chemical Society
DOI:10.1016/j.jscs.2024.101900
影响因子 :5.8
引用产品: MCF7 [MCF-7] 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , Hep G2 细胞
-
Transcription factor E2F4 facilitates SUMOylation to promote HCC progression through interaction with LIN9 (2024-09-02)
期刊:INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 :4.5
引用产品: Hep G2 细胞 , HCCLM3 细胞 , HuH-7 细胞 , HuH-6 细胞 , PLC/PRF/5 细胞
-
MTFR2 accelerates hepatocellular carcinoma mediated by metabolic reprogramming via the Akt signaling pathway (2024-08-23)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111366
影响因子 :4.4
引用产品: HuH-7 细胞 , PLC/PRF/5 细胞
-
The extract of an herbal medicine Chebulae fructus inhibits hepatocellular carcinoma by suppressing the Apelin/APJ system (2024-05-30)
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2024.1413463
影响因子 :4.4
引用产品: Hep G2 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , HCCLM3 细胞 , Hep 3B2.1-7 细胞
-
New HCC Subtypes Based on CD8 Tex-Related lncRNA Signature Could Predict Prognosis, Immunological and Drug Sensitivity Characteristics of Hepatocellular Carcinoma (2024-07-05)
期刊:Journal of Hepatocellular Carcinoma
影响因子 :4.2
引用产品: HuH-7 细胞 , PLC/PRF/5 细胞 , HL-7702 [L-02; LO2] 细胞 , Hep G2 细胞 , Hep-G2/2.2.15 细胞
-
Combining a glycolysis?related prognostic model based on scRNA?Seq with experimental verification identifies ZFP41 as a potential prognostic biomarker for HCC (2024-03-19)
期刊:Molecular Medicine Reports
影响因子 :3.4
引用产品: 293T [HEK-293T] 细胞 , HuH-7 细胞 , PLC/PRF/5 细胞
-
Liquidambaric acid inhibits the proliferation of hepatocellular carcinoma cells by targeting PPARα-RXRα to down-regulate fatty acid metabolism (2024-07-25)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2024.117042
影响因子 :3.3
引用产品: Li-7 细胞 , Annexin V-FITC/PI荧光双染细胞凋亡检测试剂盒 , Hep G2 细胞 , HuH-7 细胞 , PLC/PRF/5 细胞 , Hep 3B2.1-7 细胞
-
STAMBPL1, transcriptionally regulated by SREBP1, promotes malignant behaviors of hepatocellular carcinoma cells via Wnt/β-catenin signaling pathway (2024-08-16)
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23801
影响因子 :3.0
引用产品: PLC/PRF/5 细胞 , Hep 3B2.1-7 细胞
-
Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT (2023-10-22)
期刊:Advanced Science
影响因子 :15.1
引用产品: HCCLM3 细胞 , Hep G2 细胞 , HuH-7 细胞 , BEL-7404 细胞 , Hep 3B2.1-7 细胞 , PLC/PRF/5 细胞 , 293T [HEK-293T] 细胞
-
Conjugating 4β-NH-(5-Aminoindazole)-podophyllotoxin and Galectin-1-Targeted Aptamer for Synergistic Chemo-Immunotherapy of Hepatocellular Carcinoma (2023-05-04)
期刊:Advanced Healthcare Materials
影响因子 :10.0
引用产品: Hep G2 细胞 , HuH-7 细胞 , PLC/PRF/5 细胞 , SNU387 细胞 , MCF7 [MCF-7] 细胞 , Hepa 1-6 细胞
-
Targeting DDX11 promotes PARP inhibitor sensitivity in hepatocellular carcinoma by attenuating BRCA2-RAD51 mediated homologous recombination (2023-11-25)
期刊:ONCOGENE
DOI:10.1038/s41388-023-02898-x
影响因子 :8.0
引用产品: MHCC97-L 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞
-
Targeting NAD+ metabolism of hepatocellular carcinoma cells by lenvatinib promotes M2 macrophages reverse polarization, suppressing the HCC progression (2023-05-19)
期刊:Hepatology International
DOI:10.1007/s12072-023-10544-7
影响因子 :6.6
引用产品: Li-7 细胞 , PLC/PRF/5 细胞 , SNU-182 细胞 , SNU-387 细胞 , RAW 264.7 细胞
-
Silencing of keratin 15 impairs viability and mobility while facilitating the doxorubicin chemosensitivity by inactivating the β?catenin pathway in liver cancer (2023-08-30)
期刊:Oncology Letters
影响因子 :2.9
引用产品: HuH-7 细胞 , PLC/PRF/5 细胞 , Hep 3B2.1-7 细胞 , Hep G2 细胞 , Li-7 细胞 , RPMI-1640 培养基 , DMEM高糖 培养基 , 青霉素-链霉素溶液 (双抗),100×
-
VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4 (2022-10-14)
期刊:CANCER GENE THERAPY
DOI:10.1038/s41417-022-00540-8
影响因子 :5.9
引用产品: SK-Hep-1 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
-
SLC39A10 Upregulation Predicts Poor Prognosis, Promotes Proliferation and Migration, and Correlates with Immune Infiltration in Hepatocellular Carcinoma (2022-11-14)
期刊:Journal of Hepatocellular Carcinoma
影响因子 :5.0
引用产品: MHCC97-L 细胞 , HCCLM3 细胞 , Hep G2 细胞 , HL-7702 [L-02; LO2] 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
-
LncRNA AC026401.3 interacts with OCT1 to intensify sorafenib and lenvatinib resistance by activating E2F2 signaling in hepatocellular carcinoma (2022-09-06)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2022.113335
影响因子 :4.1
引用产品: Hep 3B2.1-7 细胞 , Hep G2 细胞 , HuH-7 细胞 , MHCC97-L 细胞 , PLC/PRF/5 细胞 , MIHA 细胞
-
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway (2021-10-30)
期刊:Acta Biochimica Et Biophysica Sinica
影响因子 :3.5
引用产品: HuH-7 细胞 , SK-Hep-1 细胞 , PLC/PRF/5 细胞
FAQs
Q:{{item.question}}
A:
产品资料


识别码示意图