产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
名称 | LX-2 (人肝星形细胞) (STR鉴定正确) |
别称 | Lieming Xu-2 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
细胞类型 | 转化细胞系 |
倍增时间 | ~48-96 hours |
STR鉴定
-
STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 17 D3S1358 13,15 D5S818 11,12 D7S820 11 D8S1179 13 D13S317 11,13 D16S539 13 D18S51 12 D19S433 13,15.2 D21S11 28,31 FGA 21,26 PentaD 12,13,15 PentaE 5,21 TH01 9.3 TPOX 8 vWA 17 D6S1043 11,12 D12S391 15,17 D2S441 11,14 -
STR鉴定图
-
参考文献
-
Impact of fine particulate matter on liver injury: evidence from human, mice and cells (2024-03-04)
期刊:JOURNAL OF HAZARDOUS MATERIALS
DOI:10.1016/j.jhazmat.2024.133958
影响因子 :13.6
引用产品: LX-2 细胞
-
Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways (2024-01-26)
期刊:ACTA PHARMACOLOGICA SINICA
DOI:10.1038/s41401-024-01226-7
影响因子 :8.2
-
Lichen pectin-containing polysaccharide from Xanthoria elegans and its ability to effectively protect LX-2 cells from H2O2-induced oxidative damage (2024-03-11)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2024.130712
影响因子 :8.2
引用产品: LX-2 细胞 , DMEM高糖 培养基
-
Esculin inhibits hepatic stellate cell activation and CCl4-induced liver fibrosis by activating the Nrf2/GPX4 signaling pathway (2024-02-17)
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2024.155465
影响因子 :7.9
引用产品: LX-2 细胞
-
CircDCBLD2 alleviates liver fibrosis by regulating ferroptosis via facilitating STUB1-mediated PARK7 ubiquitination degradation (2024-02-03)
期刊:JOURNAL OF GASTROENTEROLOGY
DOI:10.1007/s00535-023-02068-6
影响因子 :6.3
引用产品: LX-2 细胞
-
Sevelamer reverses liver fibrosis by deactivation of hepatic stellate cells (2024-03-08)
期刊:BIOCHEMICAL PHARMACOLOGY
影响因子 :5.8
引用产品: LX-2 细胞
-
Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition (2024-03-08)
期刊:Aging-US
影响因子 :5.2
-
Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells (2024-02-28)
期刊:Frontiers in Endocrinology
DOI:10.3389/fendo.2024.1344971
影响因子 :5.2
引用产品: LX-2 细胞 , DMEM高糖 (不含L-谷氨酰胺) 培养基 , DMEM高糖 (不含L-谷氨酰胺) 培养基
-
Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice (2023-02-22)
期刊:Military Medical Research
DOI:10.1186/s40779-023-00441-3
影响因子 :21.1
引用产品: LX-2 细胞
-
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice (2023-04-01)
期刊:Nature Communications
DOI:10.1038/s41467-023-37459-z
影响因子 :16.6
引用产品: LX-2 细胞
-
A biomimetic liver cancer on-a-chip reveals a critical role of LIPOCALIN-2 in promoting hepatocellular carcinoma progression (2023-05-04)
期刊:Acta Pharmaceutica Sinica B
DOI:10.1016/j.apsb.2023.04.010
影响因子 :14.5
引用产品: LX-2 细胞 , 人脐静脉内皮细胞 , NK-92 细胞 , NK-92细胞专用培养基
-
TRIM21 promotes ubiquitination of SARS-CoV-2 nucleocapsid protein to regulate innate immunity (2023-04-13)
期刊:JOURNAL OF MEDICAL VIROLOGY
影响因子 :12.7
引用产品: LX-2 细胞
-
Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases (2023-08-23)
期刊:CANCER RESEARCH
DOI:10.1158/0008-5472.CAN-23-0025
影响因子 :11.2
引用产品: LX-2 细胞
-
Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells (2023-02-28)
期刊:JOURNAL OF COLLOID AND INTERFACE SCIENCE
DOI:10.1016/j.jcis.2023.02.133
影响因子 :9.9
引用产品: Hela 细胞 , 293 [HEK-293] 细胞 , Hep G2 细胞 , LX-2 细胞
-
Enhanced glypican-3-targeted identification of hepatocellular carcinoma with liver fibrosis by pre-degrading excess fibrotic collagen (2023-01-02)
期刊:Acta Biomaterialia
DOI:10.1016/j.actbio.2022.12.062
影响因子 :9.7
引用产品: LX-2 细胞
-
The C-type lectin COLEC10 is predominantly produced by hepatic stellate cells and involved in the pathogenesis of liver fibrosis (2023-11-30)
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-06324-8
影响因子 :9.0
引用产品: LX-2 细胞
-
Ginsenoside Rb1 induces hepatic stellate cell ferroptosis to alleviate liver fibrosis via the BECN1/SLC7A11 axis (2023-11-29)
期刊:Journal of Pharmaceutical Analysis
DOI:10.1016/j.jpha.2023.11.009
影响因子 :8.8
引用产品: LX-2 细胞
-
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway (2023-04-21)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2023.114653
影响因子 :7.5
引用产品: LX-2 细胞
-
Sappanone A Alleviates the Severity of Carbon Tetrachloride-Induced Liver Fibrosis in Mice (2023-09-04)
期刊:Antioxidants
影响因子 :7.0
引用产品: AML12 细胞 , RAW 264.7 细胞 , LX-2 细胞
-
Cannabidiol alleviates perfluorooctane sulfonate-induced macrophage extracellular trap mediate inflammation and fibrosis in mice liver (2023-08-15)
期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI:10.1016/j.ecoenv.2023.115374
影响因子 :6.8
引用产品: RAW 264.7 细胞 , AML12 细胞 , LX-2 细胞
-
Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis (2023-01-23)
期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1016/j.ejmech.2023.115144
影响因子 :6.7
引用产品: J774A.1 细胞 , THP-1 细胞 , LX-2 细胞
-
Nanodrug rescues liver fibrosis via synergistic therapy with H2O2 depletion and Saikosaponin b1 sustained release (2023-02-16)
期刊:Communications Biology
DOI:10.1038/s42003-023-04473-2
影响因子 :5.9
引用产品: LX-2 细胞
-
BRD4 promotes hepatic stellate cells activation and hepatic fibrosis via mediating P300/H3K27ac/PLK1 axis (2023-03-11)
期刊:BIOCHEMICAL PHARMACOLOGY
影响因子 :5.8
引用产品: LX-2 细胞
-
Neddylation of EphB1 Regulates Its Activity and Associates with Liver Fibrosis (2023-02-08)
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.6
-
Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis (2023-11-09)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.111132
影响因子 :5.6
引用产品: LX-2 细胞
-
Gandouling inhibits hepatic fibrosis in Wilson's disease through Wnt-1/β-catenin signaling pathway (2023-04-02)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
引用产品: LX-2 细胞
-
Liuwei Wuling Tablet relieves the inflammatory transformation of hepatocellular carcinoma by inhibiting the PI3K/AKT/NF-κB signalling pathway (2023-11-11)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
-
Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death (2023-11-26)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
-
PRDM16 from hepatic stellate cells-derived extracellular vesicles promotes hepatocellular carcinoma progression (2023-11-15)
期刊:American Journal of Cancer Research
DOI:PMID:38058806
影响因子 :5.3
-
Aucubin inhibits hepatic stellate cell activation through stimulating Nrf2/Smad7 axis (2023-08-20)
期刊:EUROPEAN JOURNAL OF PHARMACOLOGY
DOI:10.1016/j.ejphar.2023.176002
影响因子 :5.0
引用产品: LX-2 细胞
-
HMGA2 knockdown alleviates the progression of nonalcoholic fatty liver disease (NAFLD) by downregulating SNAI2 expression (2023-06-01)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2023.110741
影响因子 :4.8
-
Tumor purity–associated genes influence hepatocellular carcinoma prognosis and tumor microenvironment (2023-06-26)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: Hep G2 细胞 , SK-Hep-1 细胞 , HuH-1 细胞 , LX-2 细胞
-
Inhibition of FGFR2 Signaling by Cynaroside Attenuates Liver Fibrosis (2023-04-06)
期刊:Pharmaceuticals
影响因子 :4.6
-
Selective Inhibition of Hepatic Stellate Cell and Fibroblast-derived LOXL1 Attenuates BDL and Mdr2-/- Induced Cholestatic Liver Fibrosis (2023-10-24)
期刊:AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
影响因子 :4.5
引用产品: LX-2 细胞
-
LINC00886 Facilitates Hepatocellular Carcinoma Tumorigenesis by Sequestering microRNA-409-3p and microRNA-214-5p (2023-06-07)
期刊:Journal of Hepatocellular Carcinoma
影响因子 :4.1
引用产品: LX-2 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞
-
Curcumin inhibits the activity and induces apoptosis of activated hepatic stellate cell by suppressing autophagy (2023-11-01)
期刊:JOURNAL OF CELLULAR BIOCHEMISTRY
影响因子 :4.0
引用产品: LX-2 细胞
-
c-Jun-mediated JMJD6 restoration enhances resistance of liver cancer to radiotherapy through the IL-4-activated ERK pathway (2023-04-18)
期刊:CELL BIOLOGY INTERNATIONAL
影响因子 :3.9
引用产品: LX-2 细胞 , MHCC97-L 细胞 , HuH-7 细胞
-
Kinetin inhibits hepatic stellate cell activation and induces apoptosis via interactions with the TGF-β1/Smad signaling pathway (2023-08-12)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2023.116655
影响因子 :3.8
引用产品: LX-2 细胞
-
Proanthocyanidin A2 attenuates the activation of hepatic stellate cells by activating the PPAR-γ signalling pathway (2023-08-24)
期刊:AUTOIMMUNITY
DOI:10.1080/08916934.2023.2250101
影响因子 :3.5
引用产品: LX-2 细胞
-
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation (2023-05-14)
期刊:Transplantation and Cellular Therapy
DOI:10.1016/j.jtct.2023.05.009
影响因子 :3.2
-
Filamin A is overexpressed in non-alcoholic steatohepatitis and contributes to the progression of inflammation and fibrosis (2023-02-22)
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.02.048
影响因子 :3.1
引用产品: LX-2 细胞
-
F-box and WD repeat domain containing 7 inhibits the activation of hepatic stellate cells by degrading delta-like ligand 1 to block Notch signaling pathway (2023-04-17)
期刊:Open Medicine
影响因子 :2.1
引用产品: LX-2 细胞
-
Hsa_circ_0072765 knockdown inhibits proliferation, activation and migration in transforming growth factor-beta (TGF-β)-induced hepatic stellate cells (HSCs) by the miR-197-3p/TRPV3 axis (2023-01-17)
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.0
引用产品: LX-2 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
-
miR-140-5p attenuates hepatic fibrosis by directly targeting TGFβR1 (2023-06-14)
期刊:SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
DOI:10.1080/00365521.2023.2223735
影响因子 :1.9
引用产品: LX-2 细胞
-
Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF-BB signaling pathway (2022-12-20)
期刊:METABOLISM-CLINICAL AND EXPERIMENTAL
DOI:10.1016/j.metabol.2022.155380
影响因子 :13.9
引用产品: HL-7702 [L-02; LO2] 细胞 , LX-2 细胞
-
Fibroblast growth factor 18 attenuates liver fibrosis and HSCs activation via the SMO-LATS1-YAP pathway (2002-02-20)
期刊:Pharmacological Research
DOI:10.1016/j.phrs.2022.106139
影响因子 :10.3
引用产品: LX-2 细胞
-
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence (2022-12-02)
期刊:PHARMACOLOGICAL RESEARCH
DOI:10.1016/j.phrs.2022.106590
影响因子 :10.3
引用产品: LX-2 细胞
-
CK2 blockade alleviates liver fibrosis by suppressing activation of hepatic stellate cells via the Hedgehog pathway (2022-09-07)
期刊:BRITISH JOURNAL OF PHARMACOLOGY
影响因子 :9.5
引用产品: LX-2 细胞
-
Preparation of Betulinic Acid Galactosylated Chitosan Nanoparticles and Their Effect on Liver Fibrosis (2022-09-14)
期刊:International Journal of Nanomedicine
影响因子 :7.0
引用产品: Hep G2 细胞 , LX-2 细胞 , HL-7702 [L-02; LO2] 细胞
-
Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β (2022-12-07)
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2022.154585
影响因子 :6.7
引用产品: LX-2 细胞
-
Screening of anti-liver fibrosis peptides from turtle shell protein using two-enzyme hydrolysis by molecular docking (2022-12-23)
期刊:Food & Function
影响因子 :6.3
引用产品: LX-2 细胞
-
Aucubin ameliorates liver fibrosis and hepatic stellate cells activation in diabetic mice via inhibiting ER stress-mediated IRE1α/TXNIP/NLRP3 inflammasome through NOX4/ROS pathway (2022-08-10)
期刊:CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 :5.2
引用产品: LX-2 细胞
-
Exosomal microRNA-618 derived from mesenchymal stem cells attenuate the progression of hepatic fibrosis by targeting Smad4 (2002-02-20)
期刊:Bioengineered
DOI:10.1080/21655979.2021.2023799
影响因子 :4.9
-
Long noncoding RNA HULC regulates the NF-κB pathway and represents a promising prognostic biomarker in liver cancer (2022-10-10)
期刊:Cancer Medicine
影响因子 :4.7
引用产品: Hep G2 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , LX-2 细胞
-
Extracellular vesicles derived from cancer-associated fibroblasts carry tumor-promotive microRNA-1228-3p to enhance the resistance of hepatocellular carcinoma cells to sorafenib (2022-11-23)
期刊:Human Cell
DOI:10.1007/s13577-022-00800-7
影响因子 :4.4
引用产品: LX-2 细胞 , 293T [HEK-293T] 细胞
-
Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10 (2022-12-21)
期刊:IMMUNOBIOLOGY
DOI:10.1016/j.imbio.2022.152315
影响因子 :3.2
引用产品: LX-2 细胞
-
3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway (2012-01-20)
期刊:Journal Of Nanobiotechnology
DOI:10.1186/s12951-021-01138-2
影响因子 :10.2
引用产品: LX-2 细胞
-
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis (2010-01-20)
期刊:BMC Medicine
DOI:10.1186/s12916-021-02085-3
影响因子 :9.3
引用产品: LX-2 细胞
-
Circular RNA circPSD3 alleviates hepatic fibrogenesis by regulating the miR-92b-3p/Smad7 axis (2001-01-20)
期刊:Molecular Therapy-Nucleic Acids
DOI:10.1016/j.omtn.2021.01.007
影响因子 :8.8
引用产品: LX-2 细胞
-
CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment (2008-01-20)
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.5
-
Schisandrin B Attenuates Hepatic Stellate Cell Activation and Promotes Apoptosis to Protect against Liver Fibrosis (2011-01-20)
期刊:Molecules
影响因子 :4.6
-
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway (2008-01-20)
期刊:Drug Design Development and Therapy
影响因子 :4.3
引用产品: LX-2 细胞
-
PM2.5 promotes Drp1-mediated mitophagy to induce hepatic stellate cell activation and hepatic fibrosis via regulating miR-411 (2009-01-20)
期刊:Experimental Cell Research
DOI:10.1016/j.yexcr.2021.112828
影响因子 :4.1
引用产品: LX-2 细胞
-
Discovery of catalytic-site-fluorescent probes for tracing phosphodiesterase 5 in living cells (2010-01-20)
期刊:RSC Advances
影响因子 :3.9
引用产品: LX-2 细胞
-
MicroRNA-195-3p promotes hepatic stellate cell activation and liver fibrosis by suppressing PTEN expression (2011-01-20)
期刊:Toxicology Letters
DOI:10.1016/j.toxlet.2021.11.014
影响因子 :3.5
引用产品: LX-2 细胞
-
miR221 regulates TGF-β1-induced HSC activation through inhibiting autophagy by directly targeting LAMP2 (2009-01-20)
期刊:Molecular Medicine Reports
影响因子 :3.4
引用产品: LX-2 细胞
-
Knockdown of TRIM15 inhibits the activation of hepatic stellate cells (2006-01-20)
期刊:Journal Of Molecular Histology
DOI:10.1007/s10735-021-09997-7
影响因子 :3.2
引用产品: LX-2 细胞
-
Identification of miRNA-target gene regulatory networks in liver fibrosis based on bioinformatics analysis (2008-01-20)
期刊:PeerJ
影响因子 :2.7
引用产品: LX-2 细胞
-
Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway (2006-00-20)
期刊:Signal Transduction and Targeted Therapy
影响因子 :39.3
引用产品: LX-2 细胞
-
Fe (III)@TA@IGF-2 microspheres loaded hydrogel for liver injury treatment (2004-00-20)
期刊:International Journal Of Biological Macromolecules
DOI:10.1016/j.ijbiomac.2020.04.206
影响因子 :8.2
引用产品: LX-2 细胞
-
Role of PML SUMOylation in arsenic trioxide-induced fibrosis in HSCs (2003-00-20)
期刊:Life Sciences
影响因子 :6.1
-
The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation (2003-00-20)
期刊:Bioscience Reports
影响因子 :4.0
引用产品: LX-2 细胞
-
Structures and In Vitro Antihepatic Fibrosis Activities of Prenylated Dihydrostilbenes and Flavonoids from Glycyrrhiza uralensis Leaves (2004-09-20)
期刊:Journal Of Food Science
影响因子 :3.9
引用产品: LX-2 细胞
-
Antifibrotic effects of specific siRNA targeting connective tissue growth factor delivered by polyethyleneimine‑functionalized magnetic iron oxide nanoparticles on LX‑2 cells (2011-09-20)
期刊:Molecular Medicine Reports
影响因子 :3.4
引用产品: LX-2 细胞
-
Comparative RNA-sequencing profiled the differential gene expression of liver in response to acetyl-CoA carboxylase inhibitor GS-0976 in a mouse model of NASH (2012-09-20)
期刊:PeerJ
影响因子 :3.1
引用产品: LX-2 细胞
-
Identification of key genes, pathways and potential therapeutic agents for liver fibrosis using an integrated bioinformatics analysis (2003-09-20)
期刊:PeerJ
影响因子 :2.7
引用产品: LX-2 细胞
-
Hyperoside protects against heart failure-induced liver fibrosis in rats (2007-09-20)
期刊:Acta Histochemica
DOI:10.1016/j.acthis.2019.07.005
影响因子 :2.5
引用产品: LX-2 细胞
-
MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression (2006-08-20)
期刊:Cell Death & Disease
影响因子 :9.0
引用产品: LX-2 细胞
FAQs
Q:{{item.question}}
A:
产品资料


识别码示意图