LX-2 (人肝星形细胞) (STR鉴定正确)

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参考文献

• Impact of fine particulate matter on liver injury: evidence from human, mice and cells (2024-03-04)

  作者：Yalan Xiao:1.School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai 200032, China; NHC Key Laboratory of Glycoconjugates Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China. ; Jialu Hu:1.Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. ; Renjie Chen:1.School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai 200032, China. ; Yanyi Xu:1.School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai 200032, China. ; Bin Pan:1.School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, F

  期刊：Impact of fine particulate matter on liver injury: evidence from human, mice and cells

  DOI：10.1016/j.jhazmat.2024.133958

  影响因子 ：13.6

  引用产品： LX-2 细胞

• Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways (2024-01-26)

  作者：Yan-Ni Zhao:1.Joint Research Center on Medicine, The Affiliated Xiangshan Hospital of Wenzhou Medical University, Ningbo, 315700, China. ; 2.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. ; 3.College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju, Republic of Korea. ; Zhou-di Liu:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. ; Tao Yan:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. ; Ting-Xin Xu:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. ; Tian-Yang Jin:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. ; Yong-Sheng Jiang:1.Joint Research Center on Medicine, The Af

  期刊：Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways

  DOI：10.1038/s41401-024-01226-7

  影响因子 ：8.2

  引用产品： 人肝星状细胞 ,  LX-2 细胞

• Lichen pectin-containing polysaccharide from Xanthoria elegans and its ability to effectively protect LX-2 cells from H2O2-induced oxidative damage (2024-03-11)

  作者：Zheng Zhou:1.Qinghai Provincial Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810001, China; University of Chinese Academy of Sciences, Beijing 100049, China. ; Guoqiang Li:1.Qinghai Provincial Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810001, China; University of Chinese Academy of Sciences, Beijing 100049, China. ; Liang Gao:1.Qinghai Provincial Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; CAS Key Laboratory of Tibetan Medicine Research, Northwest

  期刊：Lichen pectin-containing polysaccharide from Xanthoria elegans and its ability to effectively protect LX-2 cells from H2O2-induced oxidative damage

  DOI：10.1016/j.ijbiomac.2024.130712

  影响因子 ：8.2

  引用产品： LX-2 细胞 ,  DMEM高糖 培养基

• Esculin inhibits hepatic stellate cell activation and CCl4-induced liver fibrosis by activating the Nrf2/GPX4 signaling pathway (2024-02-17)

  作者：Shuoxi Xu:1.School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. ; Yonger Chen:1.School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. ; Jindian Miao:1.School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. ; Yuhua Li:1.School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. ; Jiaying Liu:1.School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. ; Jing Zhang:1.School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. ; Jian Liang:1.School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. ; Shuxian Chen:1.Department of Hepatobiliary Surgery, Third Affiliated Hospit

  期刊：Esculin inhibits hepatic stellate cell activation and CCl4-induced liver fibrosis by activating the Nrf2/GPX4 signaling pathway

  DOI：10.1016/j.phymed.2024.155465

  影响因子 ：7.9

  引用产品： LX-2 细胞

• CircDCBLD2 alleviates liver fibrosis by regulating ferroptosis via facilitating STUB1-mediated PARK7 ubiquitination degradation (2024-02-03)

  作者：Juan Wang:1.Department of Infectious Disease, Third Xiangya Hospital, Central South University, Hunan, 410013, China. ; Haoye Zhang:1.Department of Infectious Disease, Third Xiangya Hospital, Central South University, Hunan, 410013, China. ; Limin Chen:1.Department of Infectious Disease, Third Xiangya Hospital, Central South University, Hunan, 410013, China. ; Kangkang Fu:1.Department of Infectious Disease, Third Xiangya Hospital, Central South University, Hunan, 410013, China. ; Yu Yan:1.Department of Infectious Disease, Third Xiangya Hospital, Central South University, Hunan, 410013, China. ; Zhenguo Liu:1.Department of Infectious Disease, Third Xiangya Hospital, Central South University, Hunan, 410013, China. liuzg729@163.com. ; 2.Changsha & Hunan Key Laboratory of Viral Hepatitis, Xiangya Hospital, Central South University, Hunan, 410008, China. liuzg729@163.com. ;

  期刊：CircDCBLD2 alleviates liver fibrosis by regulating ferroptosis via facilitating STUB1-mediated PARK7 ubiquitination degradation

  DOI：10.1007/s00535-023-02068-6

  影响因子 ：6.3

  引用产品： LX-2 细胞

• Sevelamer reverses liver fibrosis by deactivation of hepatic stellate cells (2024-03-08)

  作者：Yang-Feng Lv:1.Jiangxi Provincial Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330031, China; Institute for Advanced Study, Nanchang University, Nanchang 330031, China. ; Chuan-Sheng Xie:1.Jiangxi Provincial Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330031, China. ; Zhi-Xing Liu:1.Department of Ultrasound, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China. ; Mei-Diao Kang:1.Jiangxi Provincial Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330031, China. ; Yue Liu:1.Jiangxi Provincial Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330031, China. ; Zi-Qiang Liao:1.Jiangxi Provincial Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330031, China; Institute for Advanced Study, Nanchang University, Nanchang 330031, China. ;

  期刊：Sevelamer reverses liver fibrosis by deactivation of hepatic stellate cells

  DOI：10.1016/j.bcp.2024.116121

  影响因子 ：5.8

  引用产品： LX-2 细胞

• Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition (2024-03-08)

  作者：Lu Han:1.Department of Infectious Diseases, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. ; 2.Department of Gastroenterology, Guizhou Provincial People’s Hospital, Guiyang, Guizhou Province, China. ; Guoyuan Lin:1.Department of Infectious Diseases, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. ; Jianchao Li:1.Department of Infectious Diseases, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. ; Qingxiu Zhang:1.Department of Infectious Diseases, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. ; Tao Ran:1.Department of Infectious Diseases, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. ; Tao Huang:1.Department of Infectious Diseases, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. ; Ruihan Hu:1.Department of Cardiology, Guiqian In

  期刊：Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition

  DOI：10.18632/aging.205629

  影响因子 ：5.2

  引用产品： LX-2 细胞 ,  特级胎牛血清

• Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells (2024-02-28)

  作者：Ranran Yan:1.Qinghai-Utah Joint Key Lab for High-altitude Medicine, Medical College of Qinghai University, Xining, China. ; 2.Research Center for High Altitude Medicine, Medical College of Qinghai University, Xining, China. ; 3.Key Laboratory of High-Altitude Medicine in Qinghai University, Ministry of Education, Xining, China. ; 4.Key Laboratory for Application of High-Altitude Medicine in Qinghai Province, Xining, China. ; Hao Cai:1.Oncology Department, The Fifth People's Hospital of Qinghai Provincial, Xining, China. ; Xiaofeng Zhou:1.Affiliated Hospital of Qinghai University, Xining, China. ; Guodan Bao:1.Qinghai-Utah Joint Key Lab for High-altitude Medicine, Medical College of Qinghai University, Xining, China. ; 2.Research Center for High Altitude Medicine, Medical College of Qinghai University, Xining, China. ; 3.Key Laboratory of High-Altitude Medicine in Qinghai University, Ministry of Education, Xining, China. ; 4.Affiliated Hospital of Qinghai University, Xining, China. ;

  期刊：Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells

  DOI：10.3389/fendo.2024.1344971

  影响因子 ：5.2

  引用产品： LX-2 细胞 ,  DMEM高糖 (不含L-谷氨酰胺) 培养基 ,  DMEM高糖 (不含L-谷氨酰胺) 培养基

• The diagnostic, prognostic, drug sensitivity and ceRNA internet of PPP4R1 in liver hepatocellular carcinoma (LIHC) (2024-02-26)

  作者：Xiaowei Li:1.Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, China. ; Yinglian Pan:1.Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, China. ; 2.Department of Medical Oncology, First Affiliated Hospital, Hainan Medical College, Haikou, China. ; Siren Feng:1.Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, China. ; Weimei Xing:1.Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, China. ; Bo Lin:1.Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, China. ; Wei Li:1.Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, China. ; Mengsen Li:1.Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, China. ; 2.Department of Medical Oncology, Se

  期刊：The diagnostic, prognostic, drug sensitivity and ceRNA internet of PPP4R1 in liver hepatocellular carcinoma (LIHC)

  DOI：10.21037/tcr-23-1744

  影响因子 ：0.9

  引用产品： LX-2 细胞 ,  HLE 细胞 ,  HuH-7 细胞 ,  PLC/PRF/5 细胞 ,  Hep G2 细胞 ,  特级胎牛血清

• Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice (2023-02-22)

  作者：Yun-Meng Bai:1.Department of Nephrology, Shenzhen Key Laboratory of Kidney Diseases, and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People's Hospital, the First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, 518020, China. ; Fan Yang:1.Department of Urology, Shenzhen People's Hospital, the First Affiliated Hospital, Southern University Science and Technology, the Second Clinical Medical College, Jinan University, Shenzhen, 518020, China. ; 2.Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou, 510632, China. ; Piao Luo:1.Department of Urology, Shenzhen People's Hospital, the First Affiliated Hospital, Southern University Science and Technology, the Second Clinical Medical College, Jinan University, Shenzhen, 518020, China. ; Lu-Lin Xie:1.Department of Urology, Shenzhen People's Hospital, the First Affiliated Hospital, Southern University Science and Technology, the Second Clinical Medical C

  期刊：Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

  DOI：10.1186/s40779-023-00441-3

  影响因子 ：21.1

  引用产品： LX-2 细胞

• Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice (2023-04-01)

  作者：Qi Zhao:1.Laboratory of Metabolomics and Drug-Induced Liver Injury, Department of Gastroenterology & Hepatology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, China. ; Man-Yun Dai:1.Laboratory of Metabolomics and Drug-Induced Liver Injury, Department of Gastroenterology & Hepatology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, China. ; 2.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. ; 3.University of Chinese Academy of Sciences, Beijing, 100049, China. ; Ruo-Yue Huang:1.Laboratory of Metabolomics and Drug-Induced Liver Injury, Department of Gastroenterology & Hepatology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, China. ; Jing-Yi Duan:1.Laborator

  期刊：Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice

  DOI：10.1038/s41467-023-37459-z

  影响因子 ：16.6

  引用产品： LX-2 细胞

• A biomimetic liver cancer on-a-chip reveals a critical role of LIPOCALIN-2 in promoting hepatocellular carcinoma progression (2023-05-04)

  作者：Peiliang Shen:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Medicine & Holistic Integrative Medicine, Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China. ; Yuanyuan Jia:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Medicine & Holistic Integrative Medicine, Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China. ; Weijia Zhou:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Medicine & Holistic Integrative Medicine, Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China. ; Weiwei Zheng:1.Jiangsu Key Laboratory for Pharmac

  期刊：A biomimetic liver cancer on-a-chip reveals a critical role of LIPOCALIN-2 in promoting hepatocellular carcinoma progression

  DOI：10.1016/j.apsb.2023.04.010

  影响因子 ：14.5

  引用产品： LX-2 细胞 ,  人脐静脉内皮细胞 ,  NK-92 细胞 ,  NK-92细胞专用培养基

• TRIM21 promotes ubiquitination of SARS-CoV-2 nucleocapsid protein to regulate innate immunity (2023-04-13)

  作者：Shenglan Mao:1.Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China. ; 2.The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. ; Xuefei Cai:1.The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. ; Siqiang Niu:1.Department of Clinical Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. ; Jie Wei:1.Department of Clinical Laboratory, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, Guangdong, China. ; Ning Jiang:1.School of Basic Medical Science, Chongqing Medical University, Chongqing, China. ; Haijun Deng:1.The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, Ch

  期刊：TRIM21 promotes ubiquitination of SARS-CoV-2 nucleocapsid protein to regulate innate immunity

  DOI：10.1002/jmv.28719

  影响因子 ：12.7

  引用产品： LX-2 细胞

• Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases (2023-08-23)

  作者：Yannan Zheng:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Rui Zhou:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Jianan Cai:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Nanyan Yang:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Zhaowei Wen:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Zhihua Zhang:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Huiying Sun:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Genjie Huang:1.Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ; Yijin Guan:1.Department of Oncology, Nanfang Hospital, Southern M

  期刊：Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases

  DOI：10.1158/0008-5472.CAN-23-0025

  影响因子 ：11.2

  引用产品： LX-2 细胞

• Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells (2023-02-28)

  作者：Yanzhi Xing:1.Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China. ; Yulong Xu:1.Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China. ; Yanna Lin:1.Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China. ; E Shuang:1.Key Laboratory of Biotechnology and Bioresources Utilization of Ministry of Education, Dalian Minzu University, Dalian 116600, China. ; Han Leng:1.Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China. ; Jianhua Wang:1.Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China. Electronic address: jianhuajrz@mail.neu.edu.cn. ;

  期刊：Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells

  DOI：10.1016/j.jcis.2023.02.133

  影响因子 ：9.9

  引用产品： Hela 细胞 ,  293 [HEK-293] 细胞 ,  Hep G2 细胞 ,  LX-2 细胞

• Enhanced glypican-3-targeted identification of hepatocellular carcinoma with liver fibrosis by pre-degrading excess fibrotic collagen (2023-01-02)

  作者：Jiaming Zhuo:1.Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China; CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chines Academy of Sciences, Beijing, 100190, China; Guangdong Provincial Clinical and Engineering Center of Digital Medicine, Guangzhou 510280, China. ; Yueqi Wang:1.CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chines Academy of Sciences, Beijing, 100190, China. ; Hui Hui:1.CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chines Academy of Sciences, Beijing, 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China. ; Changjian Li:1.CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chines Academy of Sciences, Beijing, 100190, China; School of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China. ; Junying Yang:1.Department of Hepatobiliary Surgery, Zhuji

  期刊：Enhanced glypican-3-targeted identification of hepatocellular carcinoma with liver fibrosis by pre-degrading excess fibrotic collagen

  DOI：10.1016/j.actbio.2022.12.062

  影响因子 ：9.7

  引用产品： LX-2 细胞

• The C-type lectin COLEC10 is predominantly produced by hepatic stellate cells and involved in the pathogenesis of liver fibrosis (2023-11-30)

  作者：Mengfan Zhang:1.Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, China. ; Yang Jing:1.Department of Hepato-Gastroenterology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, 300070, China. ; Wenze Xu:1.Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, China. ; Xiaojing Shi:1.Department of Hepato-Gastroenterology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, 300070, China. ; Wenguang Zhang:1.Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, China. ; Pengfei Chen:1.Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, China. ; Xiaocang Cao:1.Department of Hepato-Gastroenterology

  期刊：The C-type lectin COLEC10 is predominantly produced by hepatic stellate cells and involved in the pathogenesis of liver fibrosis

  DOI：10.1038/s41419-023-06324-8

  影响因子 ：9.0

  引用产品： LX-2 细胞

• Ginsenoside Rb1 induces hepatic stellate cell ferroptosis to alleviate liver fibrosis via the BECN1/SLC7A11 axis (2023-11-29)

  作者：Lifan Lin: 1.Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China; Xinmiao Li: 1.Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China; Yifei Li: 1.Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China; Zhichao Lang: 1.Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China; Yeping Li: 1.Department of Urology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China; Jianjian Zheng: 1.Key Laborato

  期刊：Ginsenoside Rb1 induces hepatic stellate cell ferroptosis to alleviate liver fibrosis via the BECN1/SLC7A11 axis

  DOI：10.1016/j.jpha.2023.11.009

  影响因子 ：8.8

  引用产品： LX-2 细胞

• Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway (2023-04-21)

  作者：Ying Sun:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Jingdan Weng:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Xiaolei Chen:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Shuyao Ma:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Yuxin Zhang:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Feng Zhang:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Zili Zhang:1.Jiangsu Key Laborat

  期刊：Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway

  DOI：10.1016/j.biopha.2023.114653

  影响因子 ：7.5

  引用产品： LX-2 细胞

• Sappanone A Alleviates the Severity of Carbon Tetrachloride-Induced Liver Fibrosis in Mice (2023-09-04)

  作者：Jing Qi:1.Department of Biochemistry and Molecular Biology, The School of Basic Medical Sciences, Fujian Medical University, No. 1, Xuefu North Road, University Town, Fuzhou 350122, China. ; Lanqian Li:1.Department of Pathology and Institute of Oncology, The School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350122, China. ; Xueqing Yan:1.Department of Biochemistry and Molecular Biology, The School of Basic Medical Sciences, Fujian Medical University, No. 1, Xuefu North Road, University Town, Fuzhou 350122, China. ; Wenxi Hua:1.Department of Pathology and Institute of Oncology, The School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350122, China. ; 2.Diagnostic Pathology Center, Fujian Medical University, Fuzhou 350122, China. ; Zixiong Zhou:1.Department of Pathology and Institute of Oncology, The School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350122, China. ; 2.Diagnostic Pathology Center, Fujian Medical University, Fuzhou 350

  期刊：Sappanone A Alleviates the Severity of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

  DOI：10.3390/antiox12091718

  影响因子 ：7.0

  引用产品： AML12 细胞 ,  RAW 264.7 细胞 ,  LX-2 细胞

• Cannabidiol alleviates perfluorooctane sulfonate-induced macrophage extracellular trap mediate inflammation and fibrosis in mice liver (2023-08-15)

  作者：Dongliu Luo:1.College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China. ; Jintao Zhang:1.College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China. ; Hang Yin:1.College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China. ; Shanshan Li:1.College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China. ; Shiwen Xu:1.College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China. Electronic address: shiwenxu@neau.edu.cn. ; Shu Li:1.College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, PR China. Electronic address: lishu@neau.edu.cn. ;

  期刊：Cannabidiol alleviates perfluorooctane sulfonate-induced macrophage extracellular trap mediate inflammation and fibrosis in mice liver

  DOI：10.1016/j.ecoenv.2023.115374

  影响因子 ：6.8

  引用产品： RAW 264.7 细胞 ,  AML12 细胞 ,  LX-2 细胞

• Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis (2023-01-23)

  作者：Jun Yang:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China. ; Minxiu Wang:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China. ; Yulan Xu:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China. ; Jing Liao:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China. ; Xiang Li:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China. ; Ying Zhou:1.Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China. ; Jintian Dai:1.Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325024, Zhejiang, China. ; Xiaobo Li:1.Chemica

  期刊：Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis

  DOI：10.1016/j.ejmech.2023.115144

  影响因子 ：6.7

  引用产品： J774A.1 细胞 ,  THP-1 细胞 ,  LX-2 细胞

• Nanodrug rescues liver fibrosis via synergistic therapy with H2O2 depletion and Saikosaponin b1 sustained release (2023-02-16)

  作者：Hongyan Dong:1.School of Pharmacy, Zhejiang Chinese Medical University, 310053, Hangzhou, P. R. China. ; Xin Han:1.School of Pharmacy, Zhejiang Chinese Medical University, 310053, Hangzhou, P. R. China. ; Min Hao:1.School of Pharmacy, Zhejiang Chinese Medical University, 310053, Hangzhou, P. R. China. ; Qiao Yang:1.School of Pharmacy, Zhejiang Chinese Medical University, 310053, Hangzhou, P. R. China. ; Qiang Lyu:1.School of Pharmacy, Zhejiang Chinese Medical University, 310053, Hangzhou, P. R. China. ; Dongxin Tang:1.Department of Science and Education, The First Affiliated Hospital of Guiyang University of Chinese Medicine, 550001, Guiyang, China. ; Zhe Shen:1.Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, 310003, Hangzhou, China. ; Kuilong Wang:1.School of Pharmacy, Zhejiang Chinese Medical University, 310053, Hangzhou, P. R. China. ; Haodan Kuang:1.School of Pharmacy, Zhejiang Chinese Medical University, 310053, Hangzh

  期刊：Nanodrug rescues liver fibrosis via synergistic therapy with H2O2 depletion and Saikosaponin b1 sustained release

  DOI：10.1038/s42003-023-04473-2

  影响因子 ：5.9

  引用产品： LX-2 细胞

• BRD4 promotes hepatic stellate cells activation and hepatic fibrosis via mediating P300/H3K27ac/PLK1 axis (2023-03-11)

  作者：Miao Cheng:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. ; Juan-Juan Li:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. ; Xue-Ni Niu:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. ; Lin Zhu:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. ; Jin-Yu Liu:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. ; Peng-Cheng Jia:1.Inflammation and Immune

  期刊：BRD4 promotes hepatic stellate cells activation and hepatic fibrosis via mediating P300/H3K27ac/PLK1 axis

  DOI：10.1016/j.bcp.2023.115497

  影响因子 ：5.8

  引用产品： LX-2 细胞

• Neddylation of EphB1 Regulates Its Activity and Associates with Liver Fibrosis (2023-02-08)

  作者：Rongxin Li:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Dan Zhang:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Yueqing Han:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Ke Chen:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Weiran Guo:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Yijun Chen:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Shuzhen Wang:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ;

  期刊：Neddylation of EphB1 Regulates Its Activity and Associates with Liver Fibrosis

  DOI：10.3390/ijms24043415

  影响因子 ：5.6

  引用产品： LX-2 细胞 ,  HSC-T6 细胞

• Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis (2023-11-09)

  作者：Shaobin Luo:1.The Third Xiangya Hospital of Central South University, Department of Hepatopancreatobiliary Surgery, 138 Tongzipo Road, Changsha City, Hunan Province, China. ; Rongkun Luo:1.The Third Xiangya Hospital of Central South University, Department of Hepatopancreatobiliary Surgery, 138 Tongzipo Road, Changsha City, Hunan Province, China. ; Huanyuan Lu:1.The Third Xiangya Hospital of Central South University, Department of Hepatopancreatobiliary Surgery, 138 Tongzipo Road, Changsha City, Hunan Province, China. ; Rui Zhang:1.The Third Xiangya Hospital of Central South University, Department of Hepatopancreatobiliary Surgery, 138 Tongzipo Road, Changsha City, Hunan Province, China. ; Gang Deng:1.The Third Xiangya Hospital of Central South University, Department of Hepatopancreatobiliary Surgery, 138 Tongzipo Road, Changsha City, Hunan Province, China. ; Hongwu Luo:1.The Third Xiangya Hospital of Central South University, Department of Hepatopancreatobiliary Surgery, 138 Tongz

  期刊：Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis

  DOI：10.1016/j.intimp.2023.111132

  影响因子 ：5.6

  引用产品： LX-2 细胞

• Gandouling inhibits hepatic fibrosis in Wilson's disease through Wnt-1/β-catenin signaling pathway (2023-04-02)

  作者：Chenglong Cheng:1.Department of Pharmacology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China. Electronic address: chenglongcheng2019@stu.ahtcm.edu.cn. ; Qiang Wang:1.Department of Pharmaceutical Preparation, School of Life and Health Sciences, Anhui University of Science and Technology, China. Electronic address: wangqiang@ahstu.edu.cn. ; Yurong Huang:1.Department of Pharmacology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China. Electronic address: yuronghuang2019@stu.ahtcm.edu.cn. ; Qiuyun Xue:1.Department of Pharmacology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China. Electronic address: xueqiuyun2019@stu.ahtcm.edu.cn. ; Yuting Wang:1.Department of Pharmacology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China. Electronic address: yutingwang@stu.ahtcm.edu.cn. ; Pen

  期刊：Gandouling inhibits hepatic fibrosis in Wilson's disease through Wnt-1/β-catenin signaling pathway

  DOI：10.1016/j.jep.2023.116445

  影响因子 ：5.4

  引用产品： LX-2 细胞

• Liuwei Wuling Tablet relieves the inflammatory transformation of hepatocellular carcinoma by inhibiting the PI3K/AKT/NF-κB signalling pathway (2023-11-11)

  作者：Yuanyuan Chen:1.College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611100, China; Department of Hepatology, the Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China. ; Zheng Song:1.Peking University 302 Clinical Medical School, Beijing, 100191, China. ; Xiaorong Hou:1.College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611100, China; Department of Hepatology, the Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China. ; Jia Liu:1.College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611100, China. ; Congyang Zheng:1.Digestive Department of the Second Medical Center, Chinese PLA General Hospital, Beijing, 100853, China. ; Xiaomei Zhao:1.College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611100, China; Department of Hepatology, the Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China. ; Guiji Lv

  期刊：Liuwei Wuling Tablet relieves the inflammatory transformation of hepatocellular carcinoma by inhibiting the PI3K/AKT/NF-κB signalling pathway

  DOI：10.1016/j.jep.2023.117406

  影响因子 ：5.4

  引用产品： HuH-7 细胞 ,  Hep G2 细胞 ,  LX-2 细胞

• Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death (2023-11-26)

  作者：Tiantian Zhang:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. ; Chuo Wang:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. ; Anning Song:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. ; Xiao Lei:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. ; Guangqiong Li:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. ; Hui Sun:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. ; Xiaoming Wang:1.School of Life Sciences, Nanjing University, Nanjing, China. ; Zhirong Geng:1.College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China. ; Guangwen Shu:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. Electronic address: shuguangwen@whu.edu.cn. ; Xukun Deng:1.School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China. Elec

  期刊：Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death

  DOI：10.1016/j.jep.2023.117495

  影响因子 ：5.4

  引用产品： AML12 细胞 ,  LX-2 细胞

• PRDM16 from hepatic stellate cells-derived extracellular vesicles promotes hepatocellular carcinoma progression (2023-11-15)

  作者：Chen Sun:1.Department of Oncology, The First Affiliated Hospital of Anhui Medical University Hefei 230032, Anhui, P. R. China. ; 2.Anhui Public Health Clinical Center Hefei 230032, Anhui, P. R. China. ; Wenwen Xu:1.Department of Oncology, The First Affiliated Hospital of Anhui Medical University Hefei 230032, Anhui, P. R. China. ; 2.Anhui Public Health Clinical Center Hefei 230032, Anhui, P. R. China. ; Yunhong Xia:1.Department of Oncology, The First Affiliated Hospital of Anhui Medical University Hefei 230032, Anhui, P. R. China. ; 2.Anhui Public Health Clinical Center Hefei 230032, Anhui, P. R. China. ; Shuomin Wang:1.Department of Oncology, The First Affiliated Hospital of Anhui Medical University Hefei 230032, Anhui, P. R. China. ; 2.Anhui Public Health Clinical Center Hefei 230032, Anhui, P. R. China. ;

  期刊：PRDM16 from hepatic stellate cells-derived extracellular vesicles promotes hepatocellular carcinoma progression

  DOI：PMID:38058806

  影响因子 ：5.3

  引用产品： LX-2 细胞 ,  HuH-7 细胞 ,  Li-7 细胞

• Aucubin inhibits hepatic stellate cell activation through stimulating Nrf2/Smad7 axis (2023-08-20)

  作者：Xu Shi:1.Department of Laboratory Medicine, Lequn Branch, The First Hospital of Jilin University, Changchun, 130031, Jilin, China. ; Wenyan Jiang:1.Department of Radiology, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. ; XiaoGuang Yang:1.National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130000, Jilin, China. ; HeMing Ma:1.Department of Gastroenterology, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. ; Zhongfeng Wang:1.Department of Hepatology, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. ; Qing Ai:1.Department of Laboratory Medicine, Lequn Branch, The First Hospital of Jilin University, Changchun, 130031, Jilin, China. ; YuTong Dong:1.Department of Hepatology, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. ; YingYu Zhang:1.Department of Hepatology, The First Hospital of Jilin University, Changchun, 130021, Jili

  期刊：Aucubin inhibits hepatic stellate cell activation through stimulating Nrf2/Smad7 axis

  DOI：10.1016/j.ejphar.2023.176002

  影响因子 ：5.0

  引用产品： LX-2 细胞

• HMGA2 knockdown alleviates the progression of nonalcoholic fatty liver disease (NAFLD) by downregulating SNAI2 expression (2023-06-01)

  作者：Jing Sun:1.Department of Gastroenterology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China. Electronic address: zgydfsdyyy_sj@163.com. ; Xiuli Jin:1.Department of Gastroenterology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China. ; Xinhe Zhang:1.Department of Gastroenterology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China. ; Birong Zhang:1.Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff University, Cardiff, UK. ;

  期刊：HMGA2 knockdown alleviates the progression of nonalcoholic fatty liver disease (NAFLD) by downregulating SNAI2 expression

  DOI：10.1016/j.cellsig.2023.110741

  影响因子 ：4.8

  引用产品： Hep G2 细胞 ,  LX-2 细胞

• Tumor purity–associated genes influence hepatocellular carcinoma prognosis and tumor microenvironment (2023-06-26)

  作者：Yan Zhao:1.Department of Organ Transplantation, Kunming Medical University First Affiliated Hospital, Kunming, China. ; Xu Xu:1.Department of Urology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China. ; Yue Wang:1.Department of Organ Transplantation, Kunming Medical University First Affiliated Hospital, Kunming, China. ; Lin D Wu:1.Department of Organ Transplantation, Kunming Medical University First Affiliated Hospital, Kunming, China. ; Rui L Luo:1.Department of Urology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China. ; Ren P Xia:1.Department of Organ Transplantation, Kunming Medical University First Affiliated Hospital, Kunming, China. ;

  期刊：Tumor purity–associated genes influence hepatocellular carcinoma prognosis and tumor microenvironment

  DOI：10.3389/fonc.2023.1197898

  影响因子 ：4.7

  引用产品： Hep G2 细胞 ,  SK-Hep-1 细胞 ,  HuH-1 细胞 ,  LX-2 细胞

• Inhibition of FGFR2 Signaling by Cynaroside Attenuates Liver Fibrosis (2023-04-06)

  作者：Qilin Meng:1.Department of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China. ; 2.National Engineering Research Center of Genetic Medicine, Guangzhou 510632, China. ; 3.Guangdong Province Key Laboratory of Bioengineering Medicine, Guangzhou 510632, China. ; 4.Guangdong Provincial Biotechnology Drug & Engineering Technology Research Center, Guangzhou 510632, China. ; Lin Luo:1.Department of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China. ; 2.National Engineering Research Center of Genetic Medicine, Guangzhou 510632, China. ; 3.Guangdong Province Key Laboratory of Bioengineering Medicine, Guangzhou 510632, China. ; 4.Guangdong Provincial Biotechnology Drug & Engineering Technology Research Center, Guangzhou 510632, China. ; Minghua Lei:1.Department of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China. ; 2.National Engineering Research Center of Ge

  期刊：Inhibition of FGFR2 Signaling by Cynaroside Attenuates Liver Fibrosis

  DOI：10.3390/ph16040548

  影响因子 ：4.6

  引用产品： LX-2 细胞 ,  HuH-7 细胞

• Selective Inhibition of Hepatic Stellate Cell and Fibroblast-derived LOXL1 Attenuates BDL and Mdr2-/- Induced Cholestatic Liver Fibrosis (2023-10-24)

  作者：Xuzhen Yan:1.Beijing Clinical Medicine Institute, Beijing Friendship Hospital, Beijing, China. ; Ning Zhang:1.Liver Research Center, Beijing Friendship Hospital, Beijing, China. ; Luyang Wei:1.Department of General Surgery, Beijing Friendship Hospital, Beijing, China. ; Wen Zhang:1.Liver Research Center, Beijing Friendship Hospital, Beijing, China. ; Tao Huang:1.Experimental and Translational Research Center, Beijing Friendship Hospital, Beijing, China. ; Weiyu Li:1.Liver Research Center, Beijing Friendship Hospital, Beijing, China. ; Wei Chen:1.Beijing Friendship Hospital, Beijing, China. ; Aiting Yang:1.Beijing Friendship Hospital, Beijing, China. ; Hong You:1.Liver Research Center, Beijing Friendship Hospital, Beijing, China. ;

  期刊：Selective Inhibition of Hepatic Stellate Cell and Fibroblast-derived LOXL1 Attenuates BDL and Mdr2-/- Induced Cholestatic Liver Fibrosis

  DOI：10.1152/ajpgi.00004.2023

  影响因子 ：4.5

  引用产品： LX-2 细胞

• LINC00886 Facilitates Hepatocellular Carcinoma Tumorigenesis by Sequestering microRNA-409-3p and microRNA-214-5p (2023-06-07)

  作者：Lu Li:1.Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University & Hebei Provincial Key Laboratory of Liver Fibrosis in Chronic Liver Diseases, Shijiazhuang, Hebei, 050051, People's Republic of China. ; Rong Ai:1.Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University & Hebei Provincial Key Laboratory of Liver Fibrosis in Chronic Liver Diseases, Shijiazhuang, Hebei, 050051, People's Republic of China. ; Xiwei Yuan:1.Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University & Hebei Provincial Key Laboratory of Liver Fibrosis in Chronic Liver Diseases, Shijiazhuang, Hebei, 050051, People's Republic of China. ; Shiming Dong:1.Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University & Hebei Provincial Key Laboratory of Liver Fibrosis in Chronic Liver Diseases, Shijiazhuang, Hebei, 050051, People's Republic of Chin

  期刊：LINC00886 Facilitates Hepatocellular Carcinoma Tumorigenesis by Sequestering microRNA-409-3p and microRNA-214-5p

  DOI：10.2147/JHC.S410891

  影响因子 ：4.1

  引用产品： LX-2 细胞 ,  Hep 3B2.1-7 细胞 ,  HuH-7 细胞

• Curcumin inhibits the activity and induces apoptosis of activated hepatic stellate cell by suppressing autophagy (2023-11-01)

  作者：Yongxiang Shu:1.Department of Gastroenterology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Yajun He:1.Department of Clinical laboratory, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Guorong Ye:1.Department of Gastroenterology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Xuyou Liu:1.Department of Gastroenterology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Jiahuang Huang:1.Department of Gastroenterology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Qinghui Zhang:1.Department of Gastroenterology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Da Tian:1.Department of Gastroenterology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Tengyan Wang:1.Department of Gastroenterology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. ; Jianchang Shu:1.Department of Gastroenterology, Guangzhou Red C

  期刊：Curcumin inhibits the activity and induces apoptosis of activated hepatic stellate cell by suppressing autophagy

  DOI：10.1002/jcb.30487

  影响因子 ：4.0

  引用产品： LX-2 细胞

• c-Jun-mediated JMJD6 restoration enhances resistance of liver cancer to radiotherapy through the IL-4-activated ERK pathway (2023-04-18)

  作者：Yong Liu:1.Department of Interventional Therapy, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, People's Republic of China. ; 2.Department of Oncology, Baoding First Central Hospital, Baoding, People's Republic of China. ; Aixia Sui:1.The First Department of Oncology, Hebei Provincial People's Hospital, Shijiazhuang, People's Republic of China. ; Jirui Sun:1.Key Laboratory of Molecular Pathology & Early Diagnosis of Tumor (Hebei province), Baoding First Central Hospital, Baoding, People's Republic of China. ; Yifan Wu:1.Department of Interventional Therapy, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, People's Republic of China. ; Fuquan Liu:1.Department of Interventional Therapy, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, People's Republic of China. ; Yang Yang:1.Health Science Center, Hebei University, Baoding, People's Republic of China. ;

  期刊：c-Jun-mediated JMJD6 restoration enhances resistance of liver cancer to radiotherapy through the IL-4-activated ERK pathway

  DOI：10.1002/cbin.12026

  影响因子 ：3.9

  引用产品： LX-2 细胞 ,  MHCC97-L 细胞 ,  HuH-7 细胞

• Kinetin inhibits hepatic stellate cell activation and induces apoptosis via interactions with the TGF-β1/Smad signaling pathway (2023-08-12)

  作者：Fu-Chang Jin:1.Division of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Jing-Jing Chen:1.Division of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Qiu-Xian Xu:1.Dongying People's Hospital, Shandong, China. ; Ming-Hui Zhou:1.Division of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Division of Gastroenterology, Tianyou Hospital, Wuhan University of Science and Technology, Wuhan, China. ; Yi Lin:1.Division of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Qi-Wei Zhang:1.Jianghan University School of Medicine, Wuhan, China. ; Chang-Chun Zhang:1.Wuhan Sixth Hospital Affiliated to Jianghan University, Wuhan, China. ; Zhen-Gang Zhang:1.Division of Gastroenterology, Tongji Hospital, Tongji

  期刊：Kinetin inhibits hepatic stellate cell activation and induces apoptosis via interactions with the TGF-β1/Smad signaling pathway

  DOI：10.1016/j.taap.2023.116655

  影响因子 ：3.8

  引用产品： LX-2 细胞

• Proanthocyanidin A2 attenuates the activation of hepatic stellate cells by activating the PPAR-γ signalling pathway (2023-08-24)

  作者：Yacong Xiao:1.Guangdong Lingnan Institute of Technology, Qingyuan, Guangdong, P.R. China. ; Xiujuan Li:1.Guangdong Lingnan Institute of Technology, Qingyuan, Guangdong, P.R. China. ; Li Wang:1.Guangdong Lingnan Institute of Technology, Qingyuan, Guangdong, P.R. China. ; Mingyue Hu:1.Guangdong Lingnan Institute of Technology, Qingyuan, Guangdong, P.R. China. ; Youlin Liu:1.Guangdong Lingnan Institute of Technology, Qingyuan, Guangdong, P.R. China. ;

  期刊：Proanthocyanidin A2 attenuates the activation of hepatic stellate cells by activating the PPAR-γ signalling pathway

  DOI：10.1080/08916934.2023.2250101

  影响因子 ：3.5

  引用产品： LX-2 细胞

• Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation (2023-05-14)

  作者：Xiangmin Wang:1.Department of Hematology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China; Blood Diseases Institute, Xuzhou Medical University, Xuzhou, China; Key Laboratory of Bone Marrow Stem Cell, Jiangsu Province, China. ; Yi Zhou:1.Department of Hematology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China; Blood Diseases Institute, Xuzhou Medical University, Xuzhou, China; Key Laboratory of Bone Marrow Stem Cell, Jiangsu Province, China. ; Qian Sun:1.Department of Hematology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China; Blood Diseases Institute, Xuzhou Medical University, Xuzhou, China; Key Laboratory of Bone Marrow Stem Cell, Jiangsu Province, China. ; Qing Zhang:1.Department of Hematology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China; Blood Diseases Institute, Xuzhou Medical University, Xuzhou, China; Key Laboratory of Bone Marrow Stem Cell, Jiangsu Province, China. ; Hongyuan Zhou:1.Depart

  期刊：Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation

  DOI：10.1016/j.jtct.2023.05.009

  影响因子 ：3.2

  引用产品： 小鼠肝窦内皮细胞 ,  LX-2 细胞

• Filamin A is overexpressed in non-alcoholic steatohepatitis and contributes to the progression of inflammation and fibrosis (2023-02-22)

  作者：Ying Lu:1.State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China. ; Mengzhu Wang:1.Molecular Toxicology Laboratory of Sichuan Provincial Education Office, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China. ; Manyu Zhao:1.Molecular Toxicology Laboratory of Sichuan Provincial Education Office, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China. ; Qianru Zhang:1.State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China; Molecular Toxicology Laboratory of Sichuan Provincial Education Office, Institute of Systems Epidemiology, West China School of Pu

  期刊：Filamin A is overexpressed in non-alcoholic steatohepatitis and contributes to the progression of inflammation and fibrosis

  DOI：10.1016/j.bbrc.2023.02.048

  影响因子 ：3.1

  引用产品： LX-2 细胞

• F-box and WD repeat domain containing 7 inhibits the activation of hepatic stellate cells by degrading delta-like ligand 1 to block Notch signaling pathway (2023-04-17)

  作者：Yufeng Sun:1.Department of Gastroenterology, The Second Hospital of Hebei Medical University, No. 215, West Heping Road, Shijiazhuang, Hebei, 050000, China. ; Lili He:1.Department of Emergency, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, Hebei, China. ; Peiran Guo:1.College of Integrated Traditional Chinese and Western Medicine, Hebei Medical University, Shijiazhuang, Hebei, China. ; Fenghua Li:1.Department of Gastroenterology, The Second Hospital of Hebei Medical University, No. 215, West Heping Road, Shijiazhuang, Hebei, 050000, China. ; Bo Wang:1.Department of Emergency, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, Hebei, China. ; Yifan Zhang:1.Department of Integrated Traditional Chinese and Western Medicine, Shijiazhuang First Hospital, Shijiazhuang, Hebei, China. ; Kai An:1.Department of Rehabilitation, Shijiazhuang First Hospital, Shijiazhuang, Hebei, China. ; Ming Peng:1.The Second Hospital of Hebei Medical Univers

  期刊：F-box and WD repeat domain containing 7 inhibits the activation of hepatic stellate cells by degrading delta-like ligand 1 to block Notch signaling pathway

  DOI：10.1515/med-2023-0634

  影响因子 ：2.1

  引用产品： LX-2 细胞

• Hsa_circ_0072765 knockdown inhibits proliferation, activation and migration in transforming growth factor-beta (TGF-β)-induced hepatic stellate cells (HSCs) by the miR-197-3p/TRPV3 axis (2023-01-17)

  作者：Yan Jin:1.Department of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an City, Shaanxi, China. ; Xueyan Guo:1.Department of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an City, Shaanxi, China. mothguoxy@126.com. ; Rong Zhang:1.Department of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an City, Shaanxi, China. ; Chunying Yan:1.Department of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an City, Shaanxi, China. ;

  期刊：Hsa_circ_0072765 knockdown inhibits proliferation, activation and migration in transforming growth factor-beta (TGF-β)-induced hepatic stellate cells (HSCs) by the miR-197-3p/TRPV3 axis

  DOI：10.14670/HH-18-586

  影响因子 ：2.0

  引用产品： LX-2 细胞 ,  DMEM高糖 培养基 ,  特级胎牛血清 ,  青霉素-链霉素溶液 (双抗)，100×

• miR-140-5p attenuates hepatic fibrosis by directly targeting TGFβR1 (2023-06-14)

  作者：Wenchao Pan:1.Department of Infectious Diseases, The Third Hospital of Hebei Medical University, Shijiazhuang, China. ; Yadong Wang:1.Department of Infectious Diseases, The Third Hospital of Hebei Medical University, Shijiazhuang, China. ; Caiyan Zhao:1.Department of Infectious Diseases, The Third Hospital of Hebei Medical University, Shijiazhuang, China. ;

  期刊：miR-140-5p attenuates hepatic fibrosis by directly targeting TGFβR1

  DOI：10.1080/00365521.2023.2223735

  影响因子 ：1.9

  引用产品： LX-2 细胞

• Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF-BB signaling pathway (2022-12-20)

  作者：Yifan Wang:1.Center for Human Genome Research, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China. ; Pengyun Wang:1.Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, China. ; Yubing Yu:1.Center for Human Genome Research, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China. ; Erwen Huang:1.Faculty of Forensic Medicine, Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, China. ; Yufeng Yao:1.Center for Human Genome Research, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science

  期刊：Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF-BB signaling pathway

  DOI：10.1016/j.metabol.2022.155380

  影响因子 ：13.9

  引用产品： HL-7702 [L-02; LO2] 细胞 ,  LX-2 细胞

• Fibroblast growth factor 18 attenuates liver fibrosis and HSCs activation via the SMO-LATS1-YAP pathway (2002-02-20)

  作者：Gaozan Tong:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Xixi Chen:1.Department of Pharmacy, Taizhou Central Hospital, Taizhou, Zhejiang, China. ; Jongsuk Lee:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Junfu Fan:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Santie Li:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Kunxuan Zhu:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Zijing Hu:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Lin Mei:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Yanru Sui:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Yonggan Dong:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325000, China. ; Ru

  期刊：Fibroblast growth factor 18 attenuates liver fibrosis and HSCs activation via the SMO-LATS1-YAP pathway

  DOI：10.1016/j.phrs.2022.106139

  影响因子 ：10.3

  引用产品： LX-2 细胞

• Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence (2022-12-02)

  作者：Danli Zhao:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Yuanyuan Gao:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Ying Su:1.Anhui Medical University, Hefei, Anhui, China. ; Yuanyuan Zhou:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Ting Yang:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Yang Li:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. ; Yingqian Wang:1.Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese

  期刊：Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence

  DOI：10.1016/j.phrs.2022.106590

  影响因子 ：10.3

  引用产品： LX-2 细胞

• CK2 blockade alleviates liver fibrosis by suppressing activation of hepatic stellate cells via the Hedgehog pathway (2022-09-07)

  作者：Junfu Fan:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Gaozan Tong:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Xixi Chen:1.Department of Pharmacy, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China. ; Santie Li:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Ying Yu:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Shunan Zhu:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Kunxuan Zhu:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Zijing Hu:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Yonggan Dong:1.School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang, China. ; Rui Chen:1.School of Pharmaceutical Science, Wenz

  期刊：CK2 blockade alleviates liver fibrosis by suppressing activation of hepatic stellate cells via the Hedgehog pathway

  DOI：10.1111/bph.15945

  影响因子 ：9.5

  引用产品： LX-2 细胞

• Preparation of Betulinic Acid Galactosylated Chitosan Nanoparticles and Their Effect on Liver Fibrosis (2022-09-14)

  作者：Zi Chao Wu:1.School of Pharmacy, Yanbian University, Yanji, 133002, People's Republic of China. ; 2.Research Institute, Shijiazhuang Yiling Pharmaceutical Co., Ltd, Shijiazhuang, 050035, People's Republic of China. ; Xin Yu Liu:1.School of Pharmacy, Yanbian University, Yanji, 133002, People's Republic of China. ; Jia Yan Liu:1.School of Pharmacy, Yanbian University, Yanji, 133002, People's Republic of China. ; Jing Shu Piao:1.School of Pharmacy, Yanbian University, Yanji, 133002, People's Republic of China. ; Ming Guan Piao:1.School of Pharmacy, Yanbian University, Yanji, 133002, People's Republic of China. ; 2.Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji, 133002, People's Republic of China. ;

  期刊：Preparation of Betulinic Acid Galactosylated Chitosan Nanoparticles and Their Effect on Liver Fibrosis

  DOI：10.2147/IJN.S373430

  影响因子 ：7.0

  引用产品： Hep G2 细胞 ,  LX-2 细胞 ,  HL-7702 [L-02; LO2] 细胞

• Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β (2022-12-07)

  作者：Changlin Du:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; Center of Traditional Chinese Medicine Formula Granule, Anhui Medical University, China. ; Jiahui Dong:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; Center of Traditional Chinese Medicine Formula Granule, Anhui Medical University, China. ; Qi Wang:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; Center of Traditional Chinese Medicine Formula Granule, Anhui Medical University, China. ; Chuanting Xu:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; Center of Traditional C

  期刊：Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β

  DOI：10.1016/j.phymed.2022.154585

  影响因子 ：6.7

  引用产品： LX-2 细胞

• Screening of anti-liver fibrosis peptides from turtle shell protein using two-enzyme hydrolysis by molecular docking (2022-12-23)

  作者：Shufan Xia:1.College of Pharmacy, Hubei University of Chinese Medicine, 16 Huangjiahu Road West, Wuhan, 430065, People's Republic of China. ; Yao Li:1.College of Pharmacy, Hubei University of Chinese Medicine, 16 Huangjiahu Road West, Wuhan, 430065, People's Republic of China. ; Pengtao You:1.Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, Hubei University of Chinese Medicine, 16 Huangjiahu Road West, Wuhan 430065, People's Republic of China. ; Chunling Hu:1.College of Pharmacy, Hubei University of Chinese Medicine, 16 Huangjiahu Road West, Wuhan, 430065, People's Republic of China. ;

  期刊：Screening of anti-liver fibrosis peptides from turtle shell protein using two-enzyme hydrolysis by molecular docking

  DOI：10.1039/D2FO03307K

  影响因子 ：6.3

  引用产品： LX-2 细胞

• Aucubin ameliorates liver fibrosis and hepatic stellate cells activation in diabetic mice via inhibiting ER stress-mediated IRE1α/TXNIP/NLRP3 inflammasome through NOX4/ROS pathway (2022-08-10)

  作者：Xiaowen Bao:1.School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Jiaqi Li:1.School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Chaoxing Ren:1.School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Jingxun Wei:1.School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Xuanzhao Lu:1.School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Xiaoxuan Wang:1.School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Wei Du:1.Institute of Advanced Materials (IAM), Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Xin Jin:1.School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, People's Republic of China. ; Beiting Ma:1.School of Pharma

  期刊：Aucubin ameliorates liver fibrosis and hepatic stellate cells activation in diabetic mice via inhibiting ER stress-mediated IRE1α/TXNIP/NLRP3 inflammasome through NOX4/ROS pathway

  DOI：10.1016/j.cbi.2022.110074

  影响因子 ：5.2

  引用产品： LX-2 细胞

• Exosomal microRNA-618 derived from mesenchymal stem cells attenuate the progression of hepatic fibrosis by targeting Smad4 (2002-02-20)

  作者：Chao Sun:1.Department of Gastroenterology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Cuicui Shi:1.Department of Gastroenterology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Xiaoyan Duan:1.Department of Gastroenterology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Yi Zhang:1.Department of Gastroenterology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Baocan Wang:1.Department of Gastroenterology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ;

  期刊：Exosomal microRNA-618 derived from mesenchymal stem cells attenuate the progression of hepatic fibrosis by targeting Smad4

  DOI：10.1080/21655979.2021.2023799

  影响因子 ：4.9

  引用产品： 人骨髓间充质干细胞 ,  LX-2 细胞

• Long noncoding RNA HULC regulates the NF-κB pathway and represents a promising prognostic biomarker in liver cancer (2022-10-10)

  作者：Shihai Liu:1.Medical Animal Lab, The Affiliated Hospital of Qingdao University, Qingdao, China. ; Lakshmi Huttad:1.Asian Liver Center, Department of Surgery, School of Medicine, Stanford University, Stanford, California, USA. ; Guifang He:1.Medical Animal Lab, The Affiliated Hospital of Qingdao University, Qingdao, China. ; Weitai He:1.National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, China. ; Changchang Liu:1.Medical Animal Lab, The Affiliated Hospital of Qingdao University, Qingdao, China. ; Duo Cai:1.Medical Animal Lab, The Affiliated Hospital of Qingdao University, Qingdao, China. ; Hao Chen:1.Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China. ; 2.Research Institute of Xi'an Jiaotong University, Hangzhou, Zhejiang,

  期刊：Long noncoding RNA HULC regulates the NF-κB pathway and represents a promising prognostic biomarker in liver cancer

  DOI：10.1002/cam4.5263

  影响因子 ：4.7

  引用产品： Hep G2 细胞 ,  Hep 3B2.1-7 细胞 ,  HuH-7 细胞 ,  LX-2 细胞

• Extracellular vesicles derived from cancer-associated fibroblasts carry tumor-promotive microRNA-1228-3p to enhance the resistance of hepatocellular carcinoma cells to sorafenib (2022-11-23)

  作者：Yijie Zhang:1.Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, No. 155, Nanjing Street, Shenyang, 110000, Liaoning Province, People's Republic of China. ; 2.The Key Laboratory of Organ Transplantation of Liaoning Province, Shenyang, 110000, Liaoning Province, People's Republic of China. ; Qi Pan:1.Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, No. 155, Nanjing Street, Shenyang, 110000, Liaoning Province, People's Republic of China. ; 2.The Key Laboratory of Organ Transplantation of Liaoning Province, Shenyang, 110000, Liaoning Province, People's Republic of China. ; Zigong Shao:1.Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, No. 155, Nanjing Street, Shenyang, 110000, Liaoning Province, People's Republic of China. shaozigong_01@sohu.com. ; 2.The Key Laboratory of Organ Transplantation of

  期刊：Extracellular vesicles derived from cancer-associated fibroblasts carry tumor-promotive microRNA-1228-3p to enhance the resistance of hepatocellular carcinoma cells to sorafenib

  DOI：10.1007/s13577-022-00800-7

  影响因子 ：4.4

  引用产品： LX-2 细胞 ,  293T [HEK-293T] 细胞

• Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10 (2022-12-21)

  作者：Yang Xu:1.Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China. ; Feng Liu:1.Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China. ; Di He:1.Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China. ; Lei Han:1.Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China. ; Xiaoyu Zheng:1.Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China. ; Mingdao Hu:1.Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China. Electronic address: humd123@163.com. ; Peng Chen:1.Department of Hepatobiliary and Pancreatic Surgery, Second Affiliate

  期刊：Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10

  DOI：10.1016/j.imbio.2022.152315

  影响因子 ：3.2

  引用产品： LX-2 细胞

• 3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway (2012-01-20)

  作者：Ning Wang:1.School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, 510006, People's Republic of China. ; 2.Laboratory of Stem Cells and Translational Medicine, Institutes for Life Sciences and School of Medicine, South China University of Technology, No.382 Waihuan East Road, Suite 406, Higher Education Mega Center, Guangzhou, 510006, People's Republic of China. ; Xiajing Li:1.Laboratory of Stem Cells and Translational Medicine, Institutes for Life Sciences and School of Medicine, South China University of Technology, No.382 Waihuan East Road, Suite 406, Higher Education Mega Center, Guangzhou, 510006, People's Republic of China. ; 2.School of Medicine, South China University of Technology, Guangzhou, 510180, People's Republic of China. ; Zhiyong Zhong:1.School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, 510006, People's Republic of Chi

  期刊：3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway

  DOI：10.1186/s12951-021-01138-2

  影响因子 ：10.2

  引用产品： LX-2 细胞

• HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis (2010-01-20)

  作者：Xiaoyu Xie:1.Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China. ; 2.Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250021, People's Republic of China. ; 3.Shandong Provincial Engineering and Technological Research Center for Liver Diseases Prevention and Control, Jinan, Shandong, 250021, People's Republic of China. ; Huanran Lv:1.Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China. ; Chenxi Liu:1.Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250021, People's Republic of China. ; Xiaonan Su:1.Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250021, People's Republic of China. ; Zhen Yu:1.Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong

  期刊：HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis

  DOI：10.1186/s12916-021-02085-3

  影响因子 ：9.3

  引用产品： LX-2 细胞

• Circular RNA circPSD3 alleviates hepatic fibrogenesis by regulating the miR-92b-3p/Smad7 axis (2001-01-20)

  作者：Fang-Tian Bu:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province 230032, China. ; 2.The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, Anhui Province 230032, China. ; 3.Institute for Liver Diseases of Anhui Medical University, Hefei, China. ; Yan Zhu:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province 230032, China. ; 2.The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province 230032, China. ; Xin Chen:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui Province 230032, China. ; 2.The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Ed

  期刊：Circular RNA circPSD3 alleviates hepatic fibrogenesis by regulating the miR-92b-3p/Smad7 axis

  DOI：10.1016/j.omtn.2021.01.007

  影响因子 ：8.8

  引用产品： LX-2 细胞

• CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment (2008-01-20)

  作者：Yinjiang Zhang:1.School of Pharmacy, Minzu University of China, Beijing, China. ; 2.Key Laboratory of Ethnomedicine, Minzu University of China, Ministry of Education, Beijing, China. ; 3.Morning Star Academic Cooperation, Shanghai, China. ; Hongyun Wei:1.Morning Star Academic Cooperation, Shanghai, China. ; 2.Department of Gastroenterology, Affiliated Hospital of Qingdao University, Qingdao, China. ; Lu Fan:1.School of Pharmacy, Minzu University of China, Beijing, China. ; 2.Key Laboratory of Ethnomedicine, Minzu University of China, Ministry of Education, Beijing, China. ; Mingyan Fang:1.School of Pharmacy, Minzu University of China, Beijing, China. ; 2.Key Laboratory of Ethnomedicine, Minzu University of China, Ministry of Education, Beijing, China. ; Xu He:1.School of Pharmacy, Minzu University of China, Beijing, China. ; 2.Key Laboratory of Ethnomedicine, Minzu University of China, Ministry of Education, Beijing, China. ; Binan Lu:1.School of Pharmacy, Minzu University of Chin

  期刊：CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment

  DOI：10.3389/fcell.2021.681372

  影响因子 ：5.5

  引用产品： Hep G2 细胞 ,  LX-2 细胞

• Schisandrin B Attenuates Hepatic Stellate Cell Activation and Promotes Apoptosis to Protect against Liver Fibrosis (2011-01-20)

  作者：Zhiman Li:1.Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. ; Lijuan Zhao:1.Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. ; Yunshi Xia:1.College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. ; Jianbo Chen:1.Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. ; Mei Hua:1.Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. ; Yinshi Sun:1.Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. ; 2.College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. ;

  期刊：Schisandrin B Attenuates Hepatic Stellate Cell Activation and Promotes Apoptosis to Protect against Liver Fibrosis

  DOI：10.3390/molecules26226882

  影响因子 ：4.6

  引用产品： HSC-T6 细胞 ,  LX-2 细胞

• Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway (2008-01-20)

  作者：Ai-Yuan Xiu:1.Department of Gastroenterology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China. ; Qian Ding:1.Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China. ; Zhen Li:1.Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China. ; Chun-Qing Zhang:1.Department of Gastroenterology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China. ; 2.Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China. ;

  期刊：Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway

  DOI：10.2147/DDDT.S317701

  影响因子 ：4.3

  引用产品： LX-2 细胞

• PM2.5 promotes Drp1-mediated mitophagy to induce hepatic stellate cell activation and hepatic fibrosis via regulating miR-411 (2009-01-20)

  作者：Zhong-Jian Wang:1.Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China. ; Hui Yu:1.Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China. ; Jin-Jin Hao:1.Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China. ; Yun Peng:1.Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China. ; Tian-Tian Yin:1.Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China. ; Yi-Ning Qiu:1.Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China. Electronic address: qiuyining24@163.com. ;

  期刊：PM2.5 promotes Drp1-mediated mitophagy to induce hepatic stellate cell activation and hepatic fibrosis via regulating miR-411

  DOI：10.1016/j.yexcr.2021.112828

  影响因子 ：4.1

  引用产品： LX-2 细胞

• Discovery of catalytic-site-fluorescent probes for tracing phosphodiesterase 5 in living cells (2010-01-20)

  作者：Meiying Qiu:1.School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China gaoyuqi@thelilab.cn gaoyq25@mail.sysu.edu.cn luohb77@163.com luohb77@mail.sysu.edu.cn. ; Deyan Wu:1.School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China gaoyuqi@thelilab.cn gaoyq25@mail.sysu.edu.cn luohb77@163.com luohb77@mail.sysu.edu.cn. ; 2.School of Pharmaceutical Sciences, Hainan University Haikou 570228 China. ; Yi-You Huang:1.School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China gaoyuqi@thelilab.cn gaoyq25@mail.sysu.edu.cn luohb77@163.com luohb77@mail.sysu.edu.cn. ; 2.School of Pharmaceutical Sciences, Hainan University Haikou 570228 China. ; Yue Huang:1.School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China gaoyuqi@thelilab.cn gaoyq25@mail.sysu.edu.cn luohb77@163.com luohb77@mail.sysu.edu.cn. ; Qian Zhou:1.School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China gaoyuqi@thelila

  期刊：Discovery of catalytic-site-fluorescent probes for tracing phosphodiesterase 5 in living cells

  DOI：10.1039/D1RA06247F

  影响因子 ：3.9

  引用产品： LX-2 细胞

• MicroRNA-195-3p promotes hepatic stellate cell activation and liver fibrosis by suppressing PTEN expression (2011-01-20)

  作者：Ao Wang:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China; Institute for Liver Diseases of Anhui Medical University, Hefei, China. ; Fang-Tian Bu:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China; Institute for Liver Diseases of Anhui Medical University, Hefei, China. ; Juan-Juan Li:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China; Institute for Liver Diseases of Anhui Medical University, Hefei, China. ; Ya-Fei Zhang:1.Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China; Institute fo

  期刊：MicroRNA-195-3p promotes hepatic stellate cell activation and liver fibrosis by suppressing PTEN expression

  DOI：10.1016/j.toxlet.2021.11.014

  影响因子 ：3.5

  引用产品： LX-2 细胞

• miR221 regulates TGF-β1-induced HSC activation through inhibiting autophagy by directly targeting LAMP2 (2009-01-20)

  作者：Ran Cheng:1.The First Department of Hepatobiliary Surgery, Tangshan Gongren Hospital, Tangshan, Hebei 063000, P.R. China. ; Hao Xu:1.Medical Insurance Office, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, P.R. China. ; Yang Hong:1.Department of Clinical Pharmacology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, P.R. China. ;

  期刊：miR221 regulates TGF-β1-induced HSC activation through inhibiting autophagy by directly targeting LAMP2

  DOI：10.3892/mmr.2021.12417

  影响因子 ：3.4

  引用产品： LX-2 细胞

• Knockdown of TRIM15 inhibits the activation of hepatic stellate cells (2006-01-20)

  作者：Junpei Zhang:1.Department of Gastroenterology, Minhang Hospital of Fudan University, 170 Shensong Road, Shanghai, 201100, China. ; Yin Chen:1.Department of Gastroenterology, Minhang Hospital of Fudan University, 170 Shensong Road, Shanghai, 201100, China. ; Yi Tian:1.Department of Gastroenterology, Minhang Hospital of Fudan University, 170 Shensong Road, Shanghai, 201100, China. yitian@fudan.edu.cn. ; Shiyao Chen:1.Department of Gastroenterology, Zhongshan Hospital of Fudan University, 180 Fenglin Road, Shanghai, 200032, China. syaochen@fudan.edu.cn. ; Hailing Liu:1.Department of Gastroenterology, Minhang Hospital of Fudan University, 170 Shensong Road, Shanghai, 201100, China. hailingliu@fudan.edu.cn. ;

  期刊：Knockdown of TRIM15 inhibits the activation of hepatic stellate cells

  DOI：10.1007/s10735-021-09997-7

  影响因子 ：3.2

  引用产品： LX-2 细胞

• Identification of miRNA-target gene regulatory networks in liver fibrosis based on bioinformatics analysis (2008-01-20)

  作者：Yang Tai:1.Laboratory of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China. ; Chong Zhao:1.Laboratory of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China. ; Jinhang Gao:1.Laboratory of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China. ; Tian Lan:1.Laboratory of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China. ; 2.Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China. ; Huan Tong:1.Laboratory of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China. ; 2.Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China. ;

  期刊：Identification of miRNA-target gene regulatory networks in liver fibrosis based on bioinformatics analysis

  DOI：10.7717/peerj.11910

  影响因子 ：2.7

  引用产品： LX-2 细胞

• Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway (2006-00-20)

  作者：Xiaoxue Yang:1.Department of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, China. ; Liping Ma:1.State Key Laboratory of Biotherapy and Cancer Centre, West China Hospital, Sichuan University, and Collaborative Innovation Centre for Biotherapy, Chengdu, 610041, China. ; 2.School of Bioscience and Technology, Chengdu medical college, Chengdu, 610500, China. ; Rong Wei:1.State Key Laboratory of Biotherapy and Cancer Centre, West China Hospital, Sichuan University, and Collaborative Innovation Centre for Biotherapy, Chengdu, 610041, China. ; Tinghong Ye:1.Department of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, China. ; JianKang Zhou:1.State Key Laboratory of Biotherapy and Cancer Centre, West China Hospital, Sichuan University, and Collaborative Innovation Centre for Biotherapy, Chengdu, 610041, China. ; Maoyao Wen:1.Department of Gastroenterology & Hepatology, West China Hospital, Sichuan Univers

  期刊：Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway

  DOI：10.1038/s41392-020-0169-z

  影响因子 ：39.3

  引用产品： LX-2 细胞

• Fe (III)@TA@IGF-2 microspheres loaded hydrogel for liver injury treatment (2004-00-20)

  作者：Jie Chen:1.Department of Hepatobiliary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; Xicheng Wang:1.Department of Hepatobiliary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; Hua Ye:1.Department of Hepatobiliary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; Zhenyan Yu:1.Teaching and Research Bureau of Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangdong, China. ; Longbao Feng:1.Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, Jinan University, Guangzhou 510632, China. ; Jing Zhou:1.School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, GD Research Center for Functional Biomaterials Engineering and Technology, Sun Yat-sen University, Guangzhou 510275, China. Electronic address: zhoujing5@mail.sysu.edu.cn. ; Ya

  期刊：Fe (III)@TA@IGF-2 microspheres loaded hydrogel for liver injury treatment

  DOI：10.1016/j.ijbiomac.2020.04.206

  影响因子 ：8.2

  引用产品： LX-2 细胞

• Role of PML SUMOylation in arsenic trioxide-induced fibrosis in HSCs (2003-00-20)

  作者：Jingyuan Dai:1.Department of Public Health, School of Medicine, Shihezi University, Shihezi, 832000, Xinjiang, China. ; Yunhua Hu:1.Department of Public Health, School of Medicine, Shihezi University, Shihezi, 832000, Xinjiang, China. ; Qiang Niu:1.Department of Public Health, School of Medicine, Shihezi University, Shihezi, 832000, Xinjiang, China. ; Guanling Song:1.Department of Public Health, School of Medicine, Shihezi University, Shihezi, 832000, Xinjiang, China. ; Haixia Wang:1.Department of Public Health, School of Medicine, Shihezi University, Shihezi, 832000, Xinjiang, China. ; Shugang Li:1.School of Public Health, Capital Medical University, No.10 Xitoutiao, You AnMen Wai, Beijing 100069, China. Electronic address: lishugang@ccmu.edu.cn. ;

  期刊：Role of PML SUMOylation in arsenic trioxide-induced fibrosis in HSCs

  DOI：10.1016/j.lfs.2020.117607

  影响因子 ：6.1

  引用产品： LX-2 细胞 ,  人肝星状细胞

• The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation (2003-00-20)

  作者：Jianjian Zhao:1.Department of Gastroenterology, the Affiliated Hospital of Qingdao University, China. ; Yueping Jiang:1.Department of Gastroenterology, the Affiliated Hospital of Qingdao University, China. ; Xueguo Sun:1.Department of Gastroenterology, the Affiliated Hospital of Qingdao University, China. ; Xishuang Liu:1.Department of Gastroenterology, the Affiliated Hospital of Qingdao University, China. ; Fuguo Liu:1.Department of Gastroenterology, the Affiliated Hospital of Qingdao University, China. ; Mingquan Song:1.Department of Gastroenterology, the Affiliated Hospital of Qingdao University, China. ; Lingyun Zhang:1.Department of Gastroenterology, the Affiliated Hospital of Qingdao University, China. ;

  期刊：The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation

  DOI：10.1042/BSR20193385

  影响因子 ：4.0

  引用产品： LX-2 细胞

• Structures and In Vitro Antihepatic Fibrosis Activities of Prenylated Dihydrostilbenes and Flavonoids from Glycyrrhiza uralensis Leaves (2004-09-20)

  作者：Yu-Hong Fan:1.State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock; Key Laboratory of Forage and Endemic Crop Biotechnology, Ministry of Education; School of Life Sciences, Inner Mongolia University, Hohhot, P.R. China. ; Rigui Ye:1.State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock; Key Laboratory of Forage and Endemic Crop Biotechnology, Ministry of Education; School of Life Sciences, Inner Mongolia University, Hohhot, P.R. China. ; Hai-Yan Xu:1.State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock; Key Laboratory of Forage and Endemic Crop Biotechnology, Ministry of Education; School of Life Sciences, Inner Mongolia University, Hohhot, P.R. China. ; Xin-Hong Feng:1.State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock; Key Laboratory of Forage and Endemic Crop Biotechnology, Ministry of Education; School of Life Sciences, Inner Mongolia University, Hohhot, P

  期刊：Structures and In Vitro Antihepatic Fibrosis Activities of Prenylated Dihydrostilbenes and Flavonoids from Glycyrrhiza uralensis Leaves

  DOI：10.1111/1750-3841.14592

  影响因子 ：3.9

  引用产品： LX-2 细胞

• Antifibrotic effects of specific siRNA targeting connective tissue growth factor delivered by polyethyleneimine‑functionalized magnetic iron oxide nanoparticles on LX‑2 cells (2011-09-20)

  作者：Qin Yu:1.Department of Clinical Laboratory, Wuhan Blood Center, Wuhan, Hubei 430000, P.R. China. ; Xiaoqin Xiong:1.Hubei Key Laboratory of Purification and Application of Plant Anticancer Active Ingredients, School of Chemistry and Life Sciences, Hubei University of Education, Wuhan, Hubei 430205, P.R. China. ; Lei Zhao:1.Department of Clinical Laboratory, Wuhan Blood Center, Wuhan, Hubei 430000, P.R. China. ; Tingting Xu:1.Department of Clinical Laboratory, Wuhan Blood Center, Wuhan, Hubei 430000, P.R. China. ; Qianhua Wang:1.Department of Obstetrics and Gynecology, Union Hospital, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China. ;

  期刊：Antifibrotic effects of specific siRNA targeting connective tissue growth factor delivered by polyethyleneimine‑functionalized magnetic iron oxide nanoparticles on LX‑2 cells

  DOI：10.3892/mmr.2019.10834

  影响因子 ：3.4

  引用产品： LX-2 细胞

• Comparative RNA-sequencing profiled the differential gene expression of liver in response to acetyl-CoA carboxylase inhibitor GS-0976 in a mouse model of NASH (2012-09-20)

  作者：Ying Lu:1.State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Healthy Food Evaluation Research Center, Sichuan University, Chengdu, China. ; 2.West China School of Public Health and West China Fourth Hospital, Healthy Food Evaluation Research Center, Sichuan University, Chengdu, China. ; Xiaolan Su:1.State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Healthy Food Evaluation Research Center, Sichuan University, Chengdu, China. ; 2.West China School of Public Health and West China Fourth Hospital, Healthy Food Evaluation Research Center, Sichuan University, Chengdu, China. ; Manyu Zhao:1.West China School of Public Health and West China Fourth Hospital, Healthy Food Evaluation Research Center, Sichuan University, Chengdu, China. ; Qianru Zhang:1.West China School of Public Health and West China Fourth Hospital, Healthy Food Evaluation Research Center, Sichuan University, Chengdu, China. ; 2.Guangdong Zhongsheng Pharmaceutical Co., L

  期刊：Comparative RNA-sequencing profiled the differential gene expression of liver in response to acetyl-CoA carboxylase inhibitor GS-0976 in a mouse model of NASH

  DOI：10.7717/peerj.8115

  影响因子 ：3.1

  引用产品： LX-2 细胞

• Identification of key genes, pathways and potential therapeutic agents for liver fibrosis using an integrated bioinformatics analysis (2003-09-20)

  作者：Zhu Zhan:1.Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Chongqing Medical University, Chongqing, China. ; 2.Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. ; Yuhe Chen:1.Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Chongqing Medical University, Chongqing, China. ; 2.Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. ; Yuanqin Duan:1.Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Chongqing Medical University, Chongqing, China. ; 2.Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. ; Lin Li:1.Department of Hepatic Disease, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China. ; Kenley Mew:1.Department of Foreign Language, Chongqing Medical University, Chongq

  期刊：Identification of key genes, pathways and potential therapeutic agents for liver fibrosis using an integrated bioinformatics analysis

  DOI：10.7717/peerj.6645

  影响因子 ：2.7

  引用产品： LX-2 细胞

• Hyperoside protects against heart failure-induced liver fibrosis in rats (2007-09-20)

  作者：Xiao Guo:1.Heart Center, Qingdao Fuwai Cardiovascular Hospital, Qingdao 266034, People's Republic of China. ; Chengzhan Zhu:1.Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266005, People's Republic of China. ; Xiaojun Liu:1.Heart Center, Qingdao Fuwai Cardiovascular Hospital, Qingdao 266034, People's Republic of China. ; Yiping Ge:1.Heart Center, Qingdao Fuwai Cardiovascular Hospital, Qingdao 266034, People's Republic of China. ; Xianyan Jiang:1.Heart Center, Qingdao Fuwai Cardiovascular Hospital, Qingdao 266034, People's Republic of China. ; Wei Zhao:1.Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266005, People's Republic of China. Electronic address: zhaoweiqdfy@126.com. ;

  期刊：Hyperoside protects against heart failure-induced liver fibrosis in rats

  DOI：10.1016/j.acthis.2019.07.005

  影响因子 ：2.5

  引用产品： LX-2 细胞

• MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression (2006-08-20)

  作者：Liping Ma:1.Department of Thoracic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, 610041, Chengdu, China. ; Xiaoxue Yang:1.Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, 610041, Chengdu, China. ; Rong Wei:1.Department of Thoracic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, 610041, Chengdu, China. ; Tinghong Ye:1.Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, 610041, Chengdu, China. ; Jian-Kang Zhou:1.Department of Thoracic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, 610041, Chengdu, China. ; Maoyao Wen:1.Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, 610041, Chengdu, China. ; Ruoting M

  期刊：MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression

  DOI：10.1038/s41419-018-0752-1

  影响因子 ：9.0

  引用产品： LX-2 细胞

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