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产品概述
| 名称 | MHCC97-L （人低转移肝癌细胞）（STR鉴定） |
| 别称 | MHCC 97-L; MHCC97L |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 年龄（性别） | 男性；39岁 |
| 组织来源 | 肝；肝癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肝细胞癌 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,13 D2S1338 20 D3S1358 15,16 D5S818 13 D7S820 10 D8S1179 12,13 D13S317 8 D16S539 12 D18S51 13,22 D19S433 13,14 D21S11 31.2 FGA 21,24 PentaD 8,9 PentaE 17,18 TH01 9 TPOX 8 vWA 14 D6S1043 12,20 D12S391 18 D2S441 15 -
STR鉴定图
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参考文献
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hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p (2025-01-08)
期刊：Scientific Reports
DOI：10.1038/s41598-025-85737-1
影响因子 ：3.8
引用产品： HCCLM3 细胞 , MHCC97-L 细胞 , Hep G2 细胞 , SMMC-7721 细胞 , HuH-7 细胞
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miR-183-5p-enriched extracellular vesicles promote the crosstalk between hepatocellular carcinoma cell and endothelial cell via SIK1/PI3K/AKT and CCL20/CCR6 signaling pathways (2025-03-06)
期刊：Frontiers in Oncology
影响因子 ：3.5
引用产品： MHCC97-L 细胞 , HuH-7 细胞 , HuH-1 细胞 , Hep 3B2.1-7 细胞 , THLE-2 细胞 , 人脐静脉内皮细胞
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CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis (2025-02-01)
期刊：CLINICAL AND EXPERIMENTAL MEDICINE
DOI：10.1007/s10238-025-01573-7
影响因子 ：3.2
引用产品： MHCC97-L 细胞 , HuH-7 细胞 , HCCLM3 细胞
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A Novel Ferroptosis-Related Gene Prognosis Signature and Identifying Atorvastatin as a Potential Therapeutic Agent for Hepatocellular Carcinoma (2025-03-18)
期刊：CURRENT ISSUES IN MOLECULAR BIOLOGY
影响因子 ：2.8
引用产品： MHCC97-L 细胞 , HuH-7 细胞
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DNAJC8: a prognostic marker and potential therapeutic target for hepatocellular carcinoma (2024-01-11)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1289548
影响因子 ：7.3
引用产品： MHCC97-L 细胞 , HuH-7 细胞
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Constructing a disulfidptosis-related prognostic signature of hepatocellular carcinoma based on single-cell sequencing and weighted co-expression network analysis (2024-05-17)
期刊：APOPTOSIS
DOI：10.1007/s10495-024-01968-z
影响因子 ：7.2
引用产品： Hep G2 细胞 , HuH-7 细胞 , MHCC97-L 细胞 , HCCLM3 细胞 , SK-Hep-1 细胞
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RASSF4 Attenuates Metabolic Dysfunction-Associated Steatotic Liver Disease Progression via Hippo Signaling and Suppresses Hepatocarcinogenesis (2024-04-30)
期刊：Cellular and Molecular Gastroenterology and Hepatology
DOI：10.1016/j.jcmgh.2024.04.005
影响因子 ：7.1
引用产品： Hep G2 细胞 , MHCC97-L 细胞 , HuH-7 细胞 , LX-2 细胞
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Exosomal ETV4 Derived From M2 Macrophages Induces Growth, Glycolysis and Stemness in Hepatocellular Carcinoma by UpRegulating SULT2B1 Expression (2024-12-06)
期刊：LIVER INTERNATIONAL
影响因子 ：6.0
引用产品： HuH-7 细胞 , MHCC97-L 细胞 , THP-1 细胞
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Exosomal circHIF1A derived from hypoxic-induced carcinoma-associated fibroblasts promotes hepatocellular carcinoma cell malignant phenotypes and immune escape (2024-06-26)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112282
影响因子 ：4.8
引用产品： HuH-7 细胞 , MHCC97-L 细胞
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The prognostic significance and potential mechanism of PFDN4 in hepatocellular carcinoma (2024-12-06)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113761
影响因子 ：4.8
引用产品： THLE-2 细胞 , MHCC97-L 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞 , HLF-a 细胞 , SNU-449 细胞
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Circ_0027791 contributes to the growth and immune evasion of hepatocellular carcinoma via the miR-496/programmed cell death ligand 1 axis in an m6A-dependent manner (2024-03-28)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , MHCC97-L细胞专用培养基 , Hep 3B2.1-7细胞专用培养基 , HuH-7细胞专用培养基
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Role of autophagy-related genes in liver cancer prognosis (2024-05-03)
期刊：GENOMICS
DOI：10.1016/j.ygeno.2024.110852
影响因子 ：4.4
引用产品： MHCC97-L 细胞 , HuH-7 细胞 , 293T [HEK-293T] 细胞 , HCCLM3 细胞 , LX-2 细胞
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Oxymatrine Inhibits PD-L1 by Downregulating IFN-γ to Promote Ferroptosis and Enhance Anti-PD-L1 Efficacy in Liver Cancer (2024-12-06)
期刊：Journal of Hepatocellular Carcinoma
影响因子 ：4.2
引用产品： Hep G2 细胞 , MHCC97-L 细胞 , H22 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , 特级胎牛血清
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High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC (2024-04-15)
期刊：American Journal of Cancer Research
影响因子 ：3.6
引用产品： HuH-7 细胞 , SNU-449 细胞 , Hep G2 细胞 , MHCC97-L 细胞 , HL-7702 [L-02; LO2] 细胞 , 特级胎牛血清
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Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma (2024-06-03)
期刊：Annals of Gastroenterological Surgery
影响因子 ：2.9
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , THLE-2 细胞 , BEL-7405 细胞 , SK-Hep-1 细胞
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N-glycosylation of Wnt3 regulates the progression of hepatocellular carcinoma by affecting Wnt/β-catenin signal pathway (2024-06-15)
期刊：World Journal of Gastrointestinal Oncology
影响因子 ：2.5
引用产品： MHCC97-L 细胞
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A Ubiquitin-Dependent Switch on MEF2D Senses Pro-Metastatic Niche Signals to Facilitate Intrahepatic Metastasis of Liver Cancer (2023-10-12)
期刊：Advanced Science
影响因子 ：15.1
引用产品： HCCLM3 细胞 , MHCC97-L 细胞
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Targeting DDX11 promotes PARP inhibitor sensitivity in hepatocellular carcinoma by attenuating BRCA2-RAD51 mediated homologous recombination (2023-11-25)
期刊：ONCOGENE
DOI：10.1038/s41388-023-02898-x
影响因子 ：8.0
引用产品： MHCC97-L 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞
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Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression (2023-09-15)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04408-9
影响因子 ：7.4
引用产品： Hep G2 细胞 , MHCC97-L细胞 , HuH-7 细胞
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FARSB Facilitates Hepatocellular Carcinoma Progression by Activating the mTORC1 Signaling Pathway (2023-11-24)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.6
引用产品： HL-7702 [L-02; LO2] 细胞 , MHCC97-L细胞 , HuH-7 细胞 , Hep G2 细胞
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Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT Pathway (2023-03-20)
期刊：Cancers
影响因子 ：5.2
引用产品： MHCC97-L细胞 , SMMC-7721 细胞
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Circ_0007429/miR-637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC (2023-03-15)
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23526
影响因子 ：4.6
引用产品： HuH-7 细胞 , Hep G2 细胞 , HCCLM3 细胞 , SK-Hep-1 细胞 , Hep 3B2.1-7 细胞 , MHCC97-L 细胞
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Matrine suppresses hepatocellular carcinoma tumorigenesis by modulating circ_0055976/miR-1179/lactate dehydrogenase A axis (2023-11-23)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： MHCC97-L 细胞 , HuH-7 细胞
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c-Jun-mediated JMJD6 restoration enhances resistance of liver cancer to radiotherapy through the IL-4-activated ERK pathway (2023-04-18)
期刊：CELL BIOLOGY INTERNATIONAL
影响因子 ：3.9
引用产品： LX-2 细胞 , MHCC97-L 细胞 , HuH-7 细胞
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Development and validation of a ubiquitin–proteasome system gene signature for prognostic prediction and immune microenvironment evaluation in hepatocellular carcinoma (2023-07-25)
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-023-05189-w
影响因子 ：3.6
引用产品： Hep G2 细胞 , HuH-7 细胞 , MHCC97-L 细胞 , HCCLM3 细胞
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HuR-induced circ_0082319 contributes to hepatocellular carcinoma by elevating PTK2 through miR-505-3p (2023-10-25)
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-023-02793-y
影响因子 ：3.6
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , MHCC97-L细胞专用培养基 , Hep 3B2.1-7细胞专用培养基 , HuH-7细胞专用培养基
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Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway (2023-03-07)
期刊：PHARMACOLOGY
影响因子 ：3.1
引用产品： MHCC97-L 细胞 , HCCLM3 细胞
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LncRNA SNHG20 silencing inhibits hepatocellular carcinoma progression by sponging miR-5095 from MBD1 (2023-06-15)
期刊：American Journal of Translational Research
DOI：PMID:37434830
影响因子 ：2.2
引用产品： HuH-7 细胞 , MHCC97-L 细胞 , Hep G2 细胞 , SMMC-7721 细胞
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The long noncoding RNA TINCR promotes self-renewal of human liver cancer stem cells through autophagy activation (2022-11-16)
期刊：Cell Death & Disease
DOI：10.1038/s41419-022-05424-1
影响因子 ：9.7
引用产品： HCCLM3 细胞 , MHCC97-L 细胞
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A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma (2022-09-06)
期刊：Frontiers in Immunology
影响因子 ：8.8
引用产品： MHCC97-L 细胞 , HuH-7 细胞 , Hep G2 细胞 , HCCLM3 细胞
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IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma (2022-12-22)
期刊：Frontiers in Immunology
影响因子 ：8.8
引用产品： MHCC97-L 细胞 , HCCLM3 细胞 , Hep G2 细胞 , SK-Hep-1 细胞 , SNU-387 细胞 , MIHA 细胞
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Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression (2022-01-12)
期刊：CELLULAR AND MOLECULAR LIFE SCIENCES
DOI：10.1007/s00018-021-04118-9
影响因子 ：8.0
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞
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Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesicles (2022-12-26)
期刊：OncoImmunology
DOI：10.1080/2162402X.2022.2152635
影响因子 ：7.7
引用产品： HuH-7 细胞 , HCCLM3 细胞 , MHCC97-L 细胞 , RPMI-1640 培养基 , BNL 1ME A.7R.1 细胞 , DMEM高糖 培养基 , 小鼠骨髓间充质干细胞 , Hank's平衡盐溶液 (HBSS)，含钙、镁，不含酚红
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A comprehensive prognostic and immunological analysis of ephrin family genes in hepatocellular carcinoma. (2022-08-16)
期刊：Frontiers in Molecular Biosciences
影响因子 ：6.1
引用产品： HCCLM3 细胞 , MHCC97-L 细胞 , SMMC-7721 细胞 , HuH-7 细胞 , Hep G2 细胞
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Parthenolide targets NF-κB (P50) to inhibit HIF-1α-mediated metabolic reprogramming of HCC (2022-10-18)
期刊：Aging-US
影响因子 ：6.0
引用产品： MHCC97-L 细胞
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KIN17 promotes cell migration and invasion through stimulating the TGF-β/Smad2 pathway in hepatocellular carcinoma (2022-12-05)
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23492
影响因子 ：5.1
引用产品： HuH-7 细胞 , MHCC-97H 细胞 , Hep G2 细胞 , MHCC97-L 细胞 , THLE-2 细胞
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Exosomes Derived from microRNA-27a-3p Overexpressing Mesenchymal Stem Cells Inhibit the Progression of Liver Cancer through Suppression of Golgi Membrane Protein 1 (2022-12-07)
期刊：Stem Cells International
影响因子 ：5.1
引用产品： Hep G2 细胞 , MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , HL-7702 [L-02; LO2] 细胞
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SLC39A10 Upregulation Predicts Poor Prognosis, Promotes Proliferation and Migration, and Correlates with Immune Infiltration in Hepatocellular Carcinoma (2022-11-14)
期刊：Journal of Hepatocellular Carcinoma
影响因子 ：5.0
引用产品： MHCC97-L 细胞 , HCCLM3 细胞 , Hep G2 细胞 , HL-7702 [L-02; LO2] 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
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LncRNA AC026401.3 interacts with OCT1 to intensify sorafenib and lenvatinib resistance by activating E2F2 signaling in hepatocellular carcinoma (2022-09-06)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2022.113335
影响因子 ：4.1
引用产品： Hep 3B2.1-7 细胞 , Hep G2 细胞 , HuH-7 细胞 , MHCC97-L 细胞 , PLC/PRF/5 细胞 , MIHA 细胞
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FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in?vitro and in?vivo (2022-11-22)
期刊：Oncology Letters
影响因子 ：3.1
引用产品： HuH-7 细胞 , HCCLM3 细胞 , MHCC97-L 细胞 , Hep 3B2.1-7 细胞
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KIF2A participates in the progression of hepatocellular carcinoma and angiogenesis by interacting with Notch1 (2022-09-22)
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.8
引用产品： MHCC97-L 细胞
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Activation of YAP1 by STK25 contributes to the progression of hepatocellular carcinoma (2022-04-06)
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2022.101797
影响因子 ：2.6
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , SNU-182 细胞
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Overexpression of circ_0001445 decelerates hepatocellular carcinoma progression by regulating miR-942-5p/ALX4 axis (2020-08-27)
期刊：Biotechnology Letters
DOI：10.1007/s10529-020-02985-z
影响因子 ：2.7
引用产品： MHCC97-L 细胞
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