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产品概述
| 名称 | H22 (小鼠肝癌细胞) (STR鉴定正确) |
| 别称 | Hepatoma-22; Hepatoma 22 |
| 种属 | 小鼠 |
| 生长特性 | 悬浮细胞 |
| 细胞形态 | 淋巴母细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 3×10^5-5×10^5cells/mL |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | H22细胞是小鼠腹水瘤细胞，体外培养传代4-5代左右，细胞活力会将低，状态会变差，可通过腹水培养恢复细胞活力。该细胞为悬浮细胞，请注意离心收集细胞悬液；请勿直接倒掉细胞培养液。 |
| 背景描述 | H22细胞是分离自小鼠腹水，由大连医科学院建立。 |
| 年龄（性别） | 不详 |
| 组织来源 | 肝；肝癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肝胆癌细胞 |
STR鉴定
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STR位点信息
18-3 11,17 6-7 13 5-5 14 X-1 25 1-2 18,19 7-1 24.2 8-1 17,18 1-1 15,16 19-2 13 15-3 19.3,20.3,25.3 12-1 17 6-4 15.3,16.3 4-2 19.3,20.3 3-2 13,14 2-1 9 13-1 16.2
11-2 16 17-2 13,15 -
STR鉴定图
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参考文献
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Targeting RORγ inhibits the growth and metastasis of hepatocellular carcinoma (2024-02-02)
作者：Qianqian Liu:1.School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China. ; Junhua Wang:1.Clinical Research Institute, The First People's Hospital of Foshan, Foshan 528000, China. ; Huizi Sun:1.School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China. ; Zhenhua Zhang:1.School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China. ; Hong Wang:1.School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China. ; Shuai Ma:1.Department of Gastrointestinal Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510120, China. ; Chenxi Zhang:1.School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China. ; Qianqian Wang:1.School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China. ; Guodi Cai:1.School of Pharmaceutical Science
期刊：Targeting RORγ inhibits the growth and metastasis of hepatocellular carcinoma
DOI：10.1016/j.ymthe.2024.01.032
影响因子 ：12.4
引用产品： H22 细胞
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The combination of Brassica rapa L. polysaccharides and cisplatin enhances the anti liver cancer effect and improves intestinal microbiota and metabolic disorders (2024-03-07)
作者：Hanrui Kong:1.Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, Key Laboratory of Special Environment Biodiversity Application and Regulation in Xinjiang, College of Life Science, Xinjiang Normal University, Urumqi 830054, China. ; Jun Yang:1.Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, Key Laboratory of Special Environment Biodiversity Application and Regulation in Xinjiang, College of Life Science, Xinjiang Normal University, Urumqi 830054, China. ; Xiaojing Wang:1.Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, Key Laboratory of Special Environment Biodiversity Application and Regulation in Xinjiang, College of Life Science, Xinjiang Normal University, Urumqi 830054, China. ; Nuramina Mamat:1.Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, Key Laboratory of Special Environment Biodiversity Application and Regulation in Xinjiang, College of Life Science,
期刊：The combination of Brassica rapa L. polysaccharides and cisplatin enhances the anti liver cancer effect and improves intestinal microbiota and metabolic disorders
DOI：10.1016/j.ijbiomac.2024.130706
影响因子 ：8.2
引用产品： H22 细胞
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Glycyrrhizic Acid-Based Liposome for Tumor-Targeted Delivery of Cantharidin (2024-01-02)
作者：Yuxiang Wang: 1.Henan Province Engineering Research Center of High Value Utilization to Natural Medical Resource in Yellow River Basin, School of Pharmacy, Henan University, Kaifeng 475004, China; Wenzhen Wang: 1.Henan Province Engineering Research Center of High Value Utilization to Natural Medical Resource in Yellow River Basin, School of Pharmacy, Henan University, Kaifeng 475004, China; Hailu Yao: 1.Henan Province Engineering Research Center of High Value Utilization to Natural Medical Resource in Yellow River Basin, School of Pharmacy, Henan University, Kaifeng 475004, China; Jingjing Wang: 1.Henan Province Engineering Research Center of High Value Utilization to Natural Medical Resource in Yellow River Basin, School of Pharmacy, Henan University, Kaifeng 475004, China; Fenghe Yang: 1.Henan Province Engineering Research Center of High Value Utilization to Natural Medical Resource in Yellow River Basin, School of Pharmacy, Henan University, Kaifeng 475004, China; Yu Zhang: 1.Henan
期刊：Glycyrrhizic Acid-Based Liposome for Tumor-Targeted Delivery of Cantharidin
影响因子 ：5.9
引用产品： H22 细胞
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Astaxanthin exerts an adjunctive anti-cancer effect through the modulation of gut microbiota and mucosal immunity (2024-01-28)
作者：Pengfei Ren:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, China. ; Han Yue:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, China. ; Qingjuan Tang:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, China. Electronic address: tangqingjuan@ouc.edu.cn. ; Yuming Wang:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, China. ; Changhu Xue:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, China. ;
期刊：Astaxanthin exerts an adjunctive anti-cancer effect through the modulation of gut microbiota and mucosal immunity
DOI：10.1016/j.intimp.2024.111553
影响因子 ：5.6
引用产品： H22 细胞
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Pathogenic Th17 cell-mediated liver fibrosis contributes to resistance to PD-L1 antibody immunotherapy in hepatocellular carcinoma (2024-02-13)
作者：Meiying Song:1.Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong 266071, PR China. ; Luoyang Wang:1.Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong 266071, PR China. ; Suli Jiang:1.Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong 266071, PR China. ; Jie Liang:1.Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong 266071, PR China. ; Wei Li:1.Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong 266071, PR China. ; Wei Rao:1.Division of Hepatology, Liver Disease Center, Organ Transplantation Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266071, PR China. ; Qiaochu Du:1.Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong 266071, PR China. ; Guixian Liu:1.Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong 266071, PR China. ; Haining M
期刊：Pathogenic Th17 cell-mediated liver fibrosis contributes to resistance to PD-L1 antibody immunotherapy in hepatocellular carcinoma
DOI：10.1016/j.intimp.2024.111601
影响因子 ：5.6
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Paeoniflorin increases the anti-tumor efficacy of sorafenib in tumor-bearing mice with liver cancer via suppressing the NF-κb/PD-l1 axis (2024-01-13)
作者：Junfei Li:1.Zhejiang Cancer Hospital, Hangzhou Institute of Medicine and Cancer (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China. ; Chenghui Zhu:1.Wannan Medical College, Wuhu, Anhui, 241000, China. ; Zengyu Zhang:1.The Second School of Clinical Medicine, Zhejiang Chinese Medical University No. 548, Binwen Road, Binjiang District, Hangzhou, Zhejiang, 310053, China. ; Xiaorong Zheng:1.Zhejiang Cancer Hospital, Hangzhou Institute of Medicine and Cancer (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China. ; Chunlei Wang:1.Zhejiang Cancer Hospital, Hangzhou Institute of Medicine and Cancer (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China. ; Hongyan Zhang:1.Zhejiang Cancer Hospital, Hangzhou Institute of Medicine and Cancer (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China. ;
期刊：Paeoniflorin increases the anti-tumor efficacy of sorafenib in tumor-bearing mice with liver cancer via suppressing the NF-κb/PD-l1 axis
DOI：10.1016/j.heliyon.2024.e24461
影响因子 ：4.0
引用产品： H22 细胞
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Suppression of hepatocellular carcinoma by Ulva lactuca ulvan via gut microbiota and metabolite interactions (2023-04-17)
作者：Yinghui Qiu:1.College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China; College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China. ; Jingxiang Xu:1.School of Basic Medicine, Gannan Medical University, Ganzhou 341000, China. ; Wei Liao:1.College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China. ; Yuxi Wen:1.College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Universidade de Vigo, Nutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Sciences, 32004 Ourense, Spain. ; Shiyue Jiang:1.School of Basic Medicine, Gannan Medical University, Ganzhou 341000, China. ; Jiahui Wen:1.College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China. ; Chao Zhao:1.College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Key Laboratory of Marine Biotechnology of
期刊：Suppression of hepatocellular carcinoma by Ulva lactuca ulvan via gut microbiota and metabolite interactions
DOI：10.1016/j.jare.2023.04.008
影响因子 ：10.7
引用产品： H22 细胞
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Nanoparticles prepared by polysaccharides extracted from Biyang floral mushroom loaded with resveratrol: Characterization, bioactivity and release behavior under in vitro digestion (2023-06-12)
作者：Keke Liu:1.School of Life Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China; Food Laboratory of Zhongyuan, Zhengzhou University, China. ; Yongqi Liu:1.School of Life Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China; Food Laboratory of Zhongyuan, Zhengzhou University, China. ; Jike Lu:1.School of Life Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China; Food Laboratory of Zhongyuan, Zhengzhou University, China. ; Xin Liu:1.School of Life Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China; Food Laboratory of Zhongyuan, Zhengzhou University, China. ; Limin Hao:1.Systems Engineering Institute, Academy of Military Sciences (AMS), Beijing, China. Electronic address: hlm2005@163.com. ; Juanjuan Yi:1.School of Life Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China; Food Laboratory of Zhongyuan, Zhengzhou University, China. Electronic address: yijuanjuanmsn@126.com. ;
期刊：Nanoparticles prepared by polysaccharides extracted from Biyang floral mushroom loaded with resveratrol: Characterization, bioactivity and release behavior under in vitro digestion
DOI：10.1016/j.foodchem.2023.136612
影响因子 ：8.8
引用产品： H22 细胞
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Astaxanthin slows down skeletal muscle atrophy in H22 tumor-bearing mice during sorafenib treatment by modulating the gut microbiota (2023-12-20)
作者：Pengfei Ren:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of, China, Qingdao, Shandong 266003, China. tangqingjuan@ouc.edu.cn. ; Han Yue:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of, China, Qingdao, Shandong 266003, China. tangqingjuan@ouc.edu.cn. ; Qingjuan Tang:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of, China, Qingdao, Shandong 266003, China. tangqingjuan@ouc.edu.cn. ; Yuming Wang:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of, China, Qingdao, Shandong 266003, China. tangqingjuan@ouc.edu.cn. ; Changhu Xue:1.State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of, China, Qingdao, Shandong
期刊：Astaxanthin slows down skeletal muscle atrophy in H22 tumor-bearing mice during sorafenib treatment by modulating the gut microbiota
影响因子 ：6.1
引用产品： H22 细胞
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Antitumor Activity of Carboxymethyl Pachymaran with Different Molecular Weights Based on Immunomodulatory and Gut Microbiota (2023-10-25)
作者：Yalin Zhao:1.College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. ; Xi Feng:1.Department of Nutrition, Food Science and Packaging, San Jose State University, San Jose, CA 95192, USA. ; Lijia Zhang:1.College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. ; Wen Huang:1.College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. ; Ying Liu:1.College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. ;
期刊：Antitumor Activity of Carboxymethyl Pachymaran with Different Molecular Weights Based on Immunomodulatory and Gut Microbiota
影响因子 ：5.9
引用产品： H22 细胞
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Engineering M1-derived nanovesicles loading with docosahexaenoic acid synergizes ferroptosis and immune activation for treating hepatocellular carcinoma (2023-03-07)
作者：Ming Meng: 1.Department of Neurology, Taizhou Third People’s Hospital, Taizhou, Jiangsu, China; **a Zhang: 1.Department of Infectious Diseases, The Affiliated Taizhou Peoples Hospital of Nan**g Medical University Taizhou School of Clinical Medicine Nan**g Medical University, Taizhou, Jiangsu, China; Yonglin Yang: 1.Department of Infectious Diseases, The Affiliated Taizhou Peoples Hospital of Nan**g Medical University Taizhou School of Clinical Medicine Nan**g Medical University, Taizhou, Jiangsu, China; Qian Li: 1.Department of Anesthesiology, The First Affiliated Hospital of Nan**g Medical University, Nan**g, Jiangsu, China; **g**g Han: 1.Department of Anesthesiology, The First Affiliated Hospital of Nan**g Medical University, Nan**g, Jiangsu, China; Yu Chen: 1.Department of Anesthesiology, The First Affiliated Hospital of Nan**g Medical University, Nan**g, Jiangsu, China; Haishi Qiao: 1.Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University,
期刊：Engineering M1-derived nanovesicles loading with docosahexaenoic acid synergizes ferroptosis and immune activation for treating hepatocellular carcinoma
DOI：10.1186/s12645-023-00166-x
影响因子 ：5.7
引用产品： H22 细胞
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Enhancing anti-tumor therapy with agmatine-cholesterol conjugate liposomes: in vitro and in vivo evidence (2023-09-27)
作者：Yanzhi Wang:1.State Key Laboratory of Esophageal Cancer Prevention & Treatment, Key Laboratory of Advanced Drug Preparation Technologies, Henan Key Laboratory of Drug Quality Control & Evaluation, School of Pharmaceutical Sciences, Ministry of Education of China, Zhengzhou University, Zhengzhou, China. wangyz@zzu.edu.cn. ; Linchao Wang:1.State Key Laboratory of Esophageal Cancer Prevention & Treatment, Key Laboratory of Advanced Drug Preparation Technologies, Henan Key Laboratory of Drug Quality Control & Evaluation, School of Pharmaceutical Sciences, Ministry of Education of China, Zhengzhou University, Zhengzhou, China. ; 2.Jining No. 1 People's Hospital, Jining, China. ; Hanyue Chang:1.State Key Laboratory of Esophageal Cancer Prevention & Treatment, Key Laboratory of Advanced Drug Preparation Technologies, Henan Key Laboratory of Drug Quality Control & Evaluation, School of Pharmaceutical Sciences, Ministry of Education of China, Zhengzhou University, Zhengzhou, China. ; Qing Sh
期刊：Enhancing anti-tumor therapy with agmatine-cholesterol conjugate liposomes: in vitro and in vivo evidence
DOI：10.1007/s13346-023-01433-5
影响因子 ：5.4
引用产品： H22 细胞
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Astaxanthin Supplementation Assists Sorafenib in Slowing Skeletal Muscle Atrophy in H22 Tumor-Bearing Mice via Reversing Abnormal Glucose Metabolism (2023-05-13)
作者：Pengfei Ren:1.Laboratory of Food Science and Human Health, College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong, 266003, China. ; Xinyue Yu:1.Laboratory of Food Science and Human Health, College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong, 266003, China. ; Qingjuan Tang:1.Laboratory of Food Science and Human Health, College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong, 266003, China. ; Yuchen Huan:1.Laboratory of Food Science and Human Health, College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong, 266003, China. ; Jie Xu:1.Laboratory of Food Science and Human Health, College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong, 266003, China. ; Yuming Wang:1.Laboratory of Food Science and Human Health, College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong, 266003, China. ; 2.Laboratory of Marine
期刊：Astaxanthin Supplementation Assists Sorafenib in Slowing Skeletal Muscle Atrophy in H22 Tumor-Bearing Mice via Reversing Abnormal Glucose Metabolism
影响因子 ：5.2
引用产品： H22 细胞
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Comparative study on the anti-tumor effect of steroids derived from different organisms in H22 tumor-bearing mice and analysis of their mechanisms (2023-12-13)
作者：Huimin Huo:1.College of Traditional Chinese Materia Medica & Key Research Laboratory for the Development and Utilization of Fungi Traditional Chinese Medicine Resources, Jilin Agricultural University, Changchun, 130118, China; Key Laboratory of Edible Fungi Resources and Utilization, Ministry of Agriculture and Rural Affairs, Jilin Agricultural University, Changchun, Jilin, 130118, China. Electronic address: huohuimin1216@163.com. ; Haiying Bao:1.College of Traditional Chinese Materia Medica & Key Research Laboratory for the Development and Utilization of Fungi Traditional Chinese Medicine Resources, Jilin Agricultural University, Changchun, 130118, China; Key Laboratory of Edible Fungi Resources and Utilization, Ministry of Agriculture and Rural Affairs, Jilin Agricultural University, Changchun, Jilin, 130118, China. Electronic address: baohaiying@jlau.edu.cn. ;
期刊：Comparative study on the anti-tumor effect of steroids derived from different organisms in H22 tumor-bearing mice and analysis of their mechanisms
DOI：10.1016/j.ejphar.2023.176269
影响因子 ：5.0
引用产品： H22 细胞
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CDK1-SRC Interaction-Dependent Transcriptional Activation of HSP90AB1 Promotes Antitumor Immunity in Hepatocellular Carcinoma (2023-11-10)
作者：Yi-Jie Zhang:1.Department of Hepatobiliary and Organ Transplantation, The First Affiliated Hospital of China Medical University, Shenyang 110001, P. R. China. ; 2.The Key Laboratory of Organ Transplantation of Liaoning Province, The First Affiliated Hospital of China Medical University, Shenyang 110001, P. R. China. ; De-Hui Yi:1.Department of Hepatobiliary and Organ Transplantation, The First Affiliated Hospital of China Medical University, Shenyang 110001, P. R. China. ; 2.The Key Laboratory of Organ Transplantation of Liaoning Province, The First Affiliated Hospital of China Medical University, Shenyang 110001, P. R. China. ;
期刊：CDK1-SRC Interaction-Dependent Transcriptional Activation of HSP90AB1 Promotes Antitumor Immunity in Hepatocellular Carcinoma
DOI：10.1021/acs.jproteome.3c00379
影响因子 ：4.4
引用产品： HuH-7 细胞 , H22 细胞 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100× , DMEM高糖 培养基
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Ajmalicine induces the pyroptosis of hepatoma cells to exert the antitumor effect (2023-12-08)
作者：Zhangchi Sun:1.Pharmacy Department, Zhejiang Rongjun Hospital, Jiaxing, Zhejiang Province, China. ; Chenfang Ma:1.Pharmacy Department, Zhejiang Rongjun Hospital, Jiaxing, Zhejiang Province, China. ; Xiaolan Zhan:1.Pharmacy Department, Zhejiang Rongjun Hospital, Jiaxing, Zhejiang Province, China. ;
期刊：Ajmalicine induces the pyroptosis of hepatoma cells to exert the antitumor effect
影响因子 ：3.6
引用产品： H22 细胞
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ALKBH5/MAP3K8 axis regulates PD-L1+ macrophage infiltration and promotes hepatocellular carcinoma progression (2022-08-01)
作者：Yu You:1.Hepatobiliary Surgery Department, Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Diguang Wen:1.Hepatobiliary Surgery Department, Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Lu Zeng:1.Department of Gastroenterology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Jiao Lu:1.Hepatobiliary Surgery Department, Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Xiao Xiao:1.Department of Gastroenterology, Chongqing University Central Hospital (Chongqing Emergency Medical Center), Chongqing 400010, China. ; Yucheng Chen:1.Hepatobiliary Surgery Department, Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Hua Song:1.Hepatobiliary Surgery Department, Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Zuojin Liu:1.Hepatobiliary Surgery Departme
期刊：ALKBH5/MAP3K8 axis regulates PD-L1+ macrophage infiltration and promotes hepatocellular carcinoma progression
影响因子 ：10.8
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞 , SK-Hep-1 细胞 , Hep G2 细胞 , H22 细胞 , THP-1 细胞
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Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer (2022-12-10)
作者：Xiao-Yan Yang:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Jin-Guo Zhang:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Qiao-Mei Zhou:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Jie-Ni Yu:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Yuan-Fei Lu:1.Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. ; Xiao-Jie Wang:1.Department of Radiology, Second Affiliated Hospital, School
期刊：Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer
DOI：10.1186/s12951-022-01738-6
影响因子 ：9.4
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Lactose-modified enzyme-sensitive branched polymers as a nanoscale liver cancer-targeting MRI contrast agent (2022-12-12)
作者：Xiaoqin Zhang:1.School of Basic Medical Science, Southwest Medical University, Luzhou,646000, China. ; Xiaoming Wang:1.Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China. luokui@scu.edu.cn. ; 2.Department of Radiology, Chongqing General Hospital, No. 118, Xingguang Avenue, Liangjiang New Area, Chongqing, 401147, China. ; Zhiqian Li:1.Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China. luokui@scu.edu.cn. ; Jun Du:1.School of Basic Medical Science, Southwest Medical University, Luzhou,646000, China. ; Xueyang Xiao:1.Department of Radiology, Huaxi MR Research Center (HMR
期刊：Lactose-modified enzyme-sensitive branched polymers as a nanoscale liver cancer-targeting MRI contrast agent
影响因子 ：8.3
引用产品： H22 细胞
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Improved anti-hepatocellular carcinoma effect by enhanced Co-delivery of Tim-3 siRNA and sorafenib via multiple pH triggered drug-eluting nanoparticles (2007-02-20)
作者：Chenghua Song:1.National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Shaanxi Provincial Center for Regenerative Medicine and Surgical Engineering, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Jia Zhang:1.National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Shaanxi Provincial Center for Regenerative Medicine and Surgical Engineering, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; 2.Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Ruichao Wen:1.National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Shaanxi Provincial Center for Regenerative Medicine and Surgical Engineering, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ; Qingshan Li:1.Departme
期刊：Improved anti-hepatocellular carcinoma effect by enhanced Co-delivery of Tim-3 siRNA and sorafenib via multiple pH triggered drug-eluting nanoparticles
DOI：10.1016/j.mtbio.2022.100350
影响因子 ：8.2
引用产品： Hepa 1-6 细胞 , H22 细胞
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Fluorinated carboxymethyl chitosan-based nano-prodrugs for precisely synergistic chemotherapy (2022-12-20)
作者：Chensong Zhang:1.Anhui Medical University, Hefei 230000, China; Department of Oncology Surgery, First Affiliated Hospital of Bengbu Medical College Bengbu, 233000, China. ; Yining Song:1.Anhui Engineering Technology Research Center of Biochemical Pharmaceutical, Bengbu Medical College, 2600 Donghai Avenue, Bengbu, Anhui 233030, China. ; Guoqing Yan:1.Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, China. Electronic address: 17017@ahu.edu.cn. ; Jiachi Ma:1.Anhui Medical University, Hefei 230000, China; Department of Oncology Surgery, First Affiliated Hospital of Bengbu Medical College Bengbu, 233000, China. Electronic address: tsmjc@hotmail.com. ;
期刊：Fluorinated carboxymethyl chitosan-based nano-prodrugs for precisely synergistic chemotherapy
DOI：10.1016/j.ijbiomac.2022.12.157
影响因子 ：8.0
引用产品： H22 细胞 , Hep G2 细胞 , A549 [A-549] 细胞 , MCF7 [MCF-7] 细胞
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Aidi injection enhances the anti-tumor impact of doxorubicin in H22 tumor-containing mice (2022-12-05)
作者：Yuan Lu:1.State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, 550004, China; The Affiliated Hospital of Guizhou Medical University, 28# Guiyi Road, Guiyang, 550004, Guizhou, China. ; Shuai Zhang:1.The Affiliated Hospital of Guizhou Medical University, 28# Guiyi Road, Guiyang, 550004, Guizhou, China. ; Xiaoqin Zhu:1.School of Pharmacy, Guizhou Medical University, No. 9, Beijing Road, Yunyan District, Guiyang, 550004, China. ; Kailiang Wang:1.School of Pharmacy, Guizhou Medical University, No. 9, Beijing Road, Yunyan District, Guiyang, 550004, China. ; Yan He:1.The Affiliated Hospital of Guizhou Medical University, 28# Guiyi Road, Guiyang, 550004, Guizhou, China. ; Chunhua Liu:1.Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, 550004, China. ; Jia Sun:1.State Key Laborator
期刊：Aidi injection enhances the anti-tumor impact of doxorubicin in H22 tumor-containing mice
影响因子 ：5.2
引用产品： H22 细胞
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Quercetin, the Ingredient of Xihuang Pills, Inhibits Hepatocellular Carcinoma by Regulating Autophagy and Macrophage Polarization (2022-12-20)
作者：Ruoxia Wu:1.School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, 410208 Changsha, Hunan, China. ; Ting Zhou:1.School of Pharmacy, Hunan University of Chinese Medicine, 410208 Changsha, Hunan, China. ; Jiaqing Xiong:1.Teaching and Research Section of Traditional Chinese Medicine Surgery, The First Hospital of Hunan University of Chinese Medicine, 410021 Changsha, Hunan, China. ; Zhen Zhang:1.College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, 410208 Changsha, Hunan, China. ; Sha Tian:1.Department of Internal Medicine, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, 410208 Changsha, Hunan, China. ; Yongli Wang:1.Oncology Department, The First Hospital of Hunan University of Chinese Medicine, 410021 Changsha, Hunan, China. ; Jindong Chen:1.Medical School, Hunan University of Chinese Medicine, 410208 Changsha, Hunan, China. ; Xuefei Tian:1.College of Integ
期刊：Quercetin, the Ingredient of Xihuang Pills, Inhibits Hepatocellular Carcinoma by Regulating Autophagy and Macrophage Polarization
影响因子 ：3.1
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Effects of Sensitized Sorafenib with a Paeoniflorin and Geniposide Mixture on Liver Cancer via the NF-κB-HIF-2α-SerpinB3 Pathway (2022-10-15)
作者：Jun-Fei Li:1.The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China. ; Xiao-Rong Zheng:1.The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China. ; Hong-Yan Zhang:1.The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China. ; Chang-Ming Shen:1.The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China. ; Guo-Xin Shen:1.The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang
期刊：Effects of Sensitized Sorafenib with a Paeoniflorin and Geniposide Mixture on Liver Cancer via the NF-κB-HIF-2α-SerpinB3 Pathway
影响因子 ：2.7
引用产品： H22 细胞
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Cantharidin-loaded biomimetic MOF nanoparticle cascade to enhance the Fenton reaction based on amplified photothermal therapy (2010-01-20)
作者：Xiao Cheng:1.School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, Liaoning 124221, China. guozm@dlut.edu.cn. ; Ye Liu:1.School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, Liaoning 124221, China. guozm@dlut.edu.cn. ; Hao Zhou:1.School of Food and Environment, Dalian University of Technology, Panjin, Liaoning 124221, China. ; Junke Leng:1.School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, Liaoning 124221, China. guozm@dlut.edu.cn. ; Xiaofeng Dai:1.School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, Liaoning 124221, China. guozm@dlut.edu.cn. ; Dong Wang:1.Panjin People's Hospital, Panjin, Liaoning 124221, China. ; Kun Ma:1.School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, Liaoning 124221, China. guozm@dlut.edu.cn. ; Changhao Cui:1.School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, Li
期刊：Cantharidin-loaded biomimetic MOF nanoparticle cascade to enhance the Fenton reaction based on amplified photothermal therapy
影响因子 ：7.6
引用产品： Hep G2 细胞 , RAW 264.7 细胞 , Hepa 1-6 细胞 , H22 细胞
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Protective effects of low-temperature plasma on cisplatin-induced nephrotoxicity (2012-01-20)
作者：Peng Guo:1.Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing, 100044, China. ; Nan Zhang:1.Department of Comparative Medicine, Laboratory Animal Center, Dalian Medical University, Dalian 116044, Liaoning, China. ; Juan Li:1.Yantai Healing Technology Co. Ltd., Yantai 264006, Shandong, China. ; Yang Liu:1.Department of Comparative Medicine, Laboratory Animal Center, Dalian Medical University, Dalian 116044, Liaoning, China. ; Yi Li:1.Yantai Healing Technology Co. Ltd., Yantai 264006, Shandong, China. ; Xuedong Wang:1.Yantai Healing Technology Co. Ltd., Yantai 264006, Shandong, China. ; Jingyu Wang:1.Department of Comparative Medicine, Laboratory Animal Center, Dalian Medical University, Dalian 116044, Liaoning, China. Electronic address: wangjingyus@163.com. ; Yupeng Wang:1.Yantai Healing Technology Co. Ltd., Yantai 264006, Shandong, China. Electronic address: 13901237491@139.com. ; Aiguo Wang:1.Department of Comparative Medicine, Laboratory
期刊：Protective effects of low-temperature plasma on cisplatin-induced nephrotoxicity
影响因子 ：6.1
引用产品： H22 细胞
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Anti-tumor effect of Inonotus hispidus petroleum ether extract in H22 tumor-bearing mice and analysis its mechanism by untargeted metabonomic (2012-01-20)
作者：Zhijun Li:1.Key Laboratory of Edible Fungi Resources and Utilization, Ministry of Agriculture and Rural Affairs, Jilin Agricultural University, Changchun, Jilin, 130118, China; College of Chinese Medicine Materials, Jilin Agricultural University, Changchun, 130118, China. Electronic address: 20191193@mails.jlau.edu.cn. ; Haiying Bao:1.Key Laboratory of Edible Fungi Resources and Utilization, Ministry of Agriculture and Rural Affairs, Jilin Agricultural University, Changchun, Jilin, 130118, China; College of Chinese Medicine Materials, Jilin Agricultural University, Changchun, 130118, China. Electronic address: baohaiying@jlau.edu.cn. ;
期刊：Anti-tumor effect of Inonotus hispidus petroleum ether extract in H22 tumor-bearing mice and analysis its mechanism by untargeted metabonomic
影响因子 ：5.4
引用产品： H22 细胞
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KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D (2007-01-20)
作者：Yonglan Wang:1.Department of Gastrointestinal Endoscopy Room, Jingmen No. 1 People's Hospital, Hubei, China. ; Kun Cao:1.Department of Gastroenterology, Jingmen No. 1 People's Hospital, 168 Xiangshan Road, Jingmen 448000, China. ;
期刊：KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D
影响因子 ：4.5
引用产品： HL-7702 [L-02; LO2] , SMMC-7721 细胞 , Hep G2 细胞 , H22 细胞
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Cistanche tubulosa Phenylethanoid Glycosides Induce Apoptosis of Hepatocellular Carcinoma Cells by Mitochondria-Dependent and MAPK Pathways and Enhance Antitumor Effect through Combination with Cisplatin: (2005-01-20)
作者：Pengfei Yuan:1.Xinjiang University, Urumqi, Xinjiang, China. ; Changshuang Fu:1.Xinjiang University, Urumqi, Xinjiang, China. ; Yi Yang:1.Xinjiang University, Urumqi, Xinjiang, China. ; Aipire Adila:1.Xinjiang University, Urumqi, Xinjiang, China. ; Fangfang Zhou:1.Xinjiang University, Urumqi, Xinjiang, China. ; Xianxian Wei:1.Xinjiang University, Urumqi, Xinjiang, China. ; Weilan Wang:1.Xinjiang University, Urumqi, Xinjiang, China. ; Jie Lv:1.Xinjiang University, Urumqi, Xinjiang, China. ; Yijie Li:1.Xinjiang University, Urumqi, Xinjiang, China. ; Lijie Xia:1.Xinjiang University, Urumqi, Xinjiang, China. ; Jinyao Li:1.Xinjiang University, Urumqi, Xinjiang, China. ;
期刊：Cistanche tubulosa Phenylethanoid Glycosides Induce Apoptosis of Hepatocellular Carcinoma Cells by Mitochondria-Dependent and MAPK Pathways and Enhance Antitumor Effect through Combination with Cisplatin:
影响因子 ：2.9
引用产品： H22 细胞
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Ultrasound Molecular Imaging as a Potential Non-invasive Diagnosis to Detect the Margin of Hepatocarcinoma via CSF-1R Targeting (2007-00-20)
作者：Qiongchao Jiang:1.Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; 2.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; Yunting Zeng:1.Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; 2.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; Yanni Xu:1.Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; 2.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; Xiaoyun Xiao:1.Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; Hejun Liu:1.Department of Hyperbaric O
期刊：Ultrasound Molecular Imaging as a Potential Non-invasive Diagnosis to Detect the Margin of Hepatocarcinoma via CSF-1R Targeting
影响因子 ：5.7
引用产品： H22 细胞
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Radiosensitization potential of caffeic acid phenethyl ester and the long non-coding RNAs in response to 60Coγ radiation in mouse hepatoma cells (2012-00-20)
作者：Xiaomiao Zhang: 1.School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China; Qiaozhen Kang: 1.School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China; Zhenyu Ji: 1.Henan Academy of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450052, China; Limin Hao: 1.The Quartermaster Research Institute of Engineering and Technology, Academy of Military Sciences PLA China, Beijing, 100010, China; Ting Wang: 1.School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China; Jiaqing Zhu: 1.School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China; Jike Lu: 1.School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China; Juanjuan Yi: 1.School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China;
期刊：Radiosensitization potential of caffeic acid phenethyl ester and the long non-coding RNAs in response to 60Coγ radiation in mouse hepatoma cells
DOI：10.1016/j.radphyschem.2020.109326
影响因子 ：2.9
引用产品： H22 细胞
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Antitumor Effects of Curcumin and Glycyrrhetinic Acid-Modified Curcumin-Loaded Cationic Liposome by Intratumoral Administration (2005-00-20)
作者：Mingxiang Chang:1.Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, Hubei University of Chinese Medicine, Wuhan 430061, China. ; Meimei Wu:1.Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430061, China. ; 2.Hubei Province Academy of Traditional Chinese Medicine, Wuhan 430074, China. ; Hanmin Li:1.Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430061, China. ; 2.Hubei Province Academy of Traditional Chinese Medicine, Wuhan 430074, China. ;
期刊：Antitumor Effects of Curcumin and Glycyrrhetinic Acid-Modified Curcumin-Loaded Cationic Liposome by Intratumoral Administration
影响因子 ：2.7
引用产品： H22 细胞
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Disruption of SIRT7 Increases the Efficacy of Checkpoint Inhibitor via MEF2D Regulation of Programmed Cell Death 1 Ligand 1 in Hepatocellular Carcinoma Cells (2010-09-20)
作者：Junyu Xiang:1.Center of Biotherapy, Southwest Hospital, Army Medical University, Chongqing, China. ; Ni Zhang:1.Center of Biotherapy, Southwest Hospital, Army Medical University, Chongqing, China. ; Hui Sun:1.Center of Biotherapy, Southwest Hospital, Army Medical University, Chongqing, China. ; Li Su:1.Department of Oncology, Chinese Traditional Medicine Hospital, Chongqing, China. ; Chengcheng Zhang:1.Department of Hepatobiliary Surgery, Southwest Hospital, Army Medical University, Chongqing, China. ; Huailong Xu:1.Center of Biotherapy, Southwest Hospital, Army Medical University, Chongqing, China. ; Juan Feng:1.Center of Biotherapy, Southwest Hospital, Army Medical University, Chongqing, China; Center for Precision Medicine of Cancer, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, China. ; Meiling Wang:1.Center of Biotherapy, Southwest Hospital, Army Medical University, Cho
期刊：Disruption of SIRT7 Increases the Efficacy of Checkpoint Inhibitor via MEF2D Regulation of Programmed Cell Death 1 Ligand 1 in Hepatocellular Carcinoma Cells
DOI：10.1053/j.gastro.2019.10.025
影响因子 ：29.4
引用产品： H22 细胞 , Hepa 1-6 细胞
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Assisting anti-PD-1 antibody treatment with a liposomal system capable of recruiting immune cells (2004-09-20)
作者：Boyang Zhou:1.Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province, China. luobm@mail.sysu.edu.cn. ; Qiongchao Jiang: Xiaoyun Xiao: Xiaolin Xu: Yanni Xu: Yao Kong: Wenyue Zhang: Yunting Zeng: Xiaodi Liu: Baoming Luo:
期刊：Assisting anti-PD-1 antibody treatment with a liposomal system capable of recruiting immune cells
影响因子 ：6.7
引用产品： H22 细胞
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EGCG enhances cancer cells sensitivity under 60Coγ radiation based on miR-34a/Sirt1/p53 (2009-09-20)
作者：Qiaozhen Kang:1.School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. ; Xiaomiao Zhang:1.School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. ; Nana Cao:1.School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. ; Chen Chen:1.School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. ; Juanjuan Yi:1.School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. ; Limin Hao:1.The Quartermaster Research Institute of Engineering and Technology, Academy of Military Sciences PLA China, Beijing, 100010, China. Electronic address: hlm2005@163.com. ; Yizhi Ji:1.Biochemical Engineering College, Beijing Union University, Beijing, 100010, China. ; Xin Liu:1.School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. ; Jike Lu:1.School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. Electronic address: ljk002004@163.com. ;
期刊：EGCG enhances cancer cells sensitivity under 60Coγ radiation based on miR-34a/Sirt1/p53
影响因子 ：4.3
引用产品： H22 细胞
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