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  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)

Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)

货号:CL-0202

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:McCoy’s 5A15% FBS1% P/S

数量: - +

  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
  • Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)

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产品概述
产品信息
名称 Saos-2 (人成骨肉瘤细胞) (STR鉴定正确)
别称 SAOS-2; Saos-2; SAOS 2; Saos 2; Saos2; SaOs2; SAOS2; Sarcoma OSteogenic-2; SaOS; SAOS
种属
生长特性 贴壁细胞
细胞形态 上皮细胞样
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养方案A(默认)
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:2-1:3
推荐换液频率 2-3次/周
参考资料(来源文献)
背景描述 Saos-2细胞是由J·Fogh和G·Trempe分离和鉴定的众多人肿瘤细胞系中的一种。该病人曾经多种药物治疗,包括RTG、methotrexate、adriamycin vincristine、cytoxan和aramycin-C。Saos-2细胞在免疫抑制小鼠中不致瘤,但在半固体培养基中形成集落。
年龄(性别) 女性;11岁
组织来源 骨;骨肉瘤
细胞类型 肿瘤细胞
肿瘤类型 肉瘤细胞
生物安全等级 BSL-1
倍增时间 ~48 hours
致瘤性 No, The cells were not tumorigenic in immunosuppressed mice, but did form colonies in semisolid medium.
受体表达情况 epidermal growth factor (EGF); transforming growth factor beta (Type 1 and Type 2)
抗原表达情况 Blood Type B, Rh+; HLA A2, A3, Bw16, Bw47
保藏机构 ATCC; CRL-7939ATCC; HTB-85 DSMZ; ACC-243 ECACC; 89050205
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 10
    D2S1338 18
    D3S1358 18
    D5S818 12
    D7S820 8,10
    D8S1179 10,12
    D13S317 12,13
    D16S539 12,13
    D18S51 15
    D19S433 13
    D21S11 28,30
    FGA 22,25
    PentaD 11,12
    PentaE 14,19
    TH01 6,9
    TPOX 8
    vWA 18
    D6S1043 11,14
    D12S391 20
    D2S441 10,14
  • STR鉴定图
参考文献
文献列表
  • Single-Atom Cu Nanozyme-Loaded Bone Scaffolds for Ferroptosis-Synergized Mild Photothermal Therapy in Osteosarcoma Treatment (2024-02-29)

    作者:Zuyun Yan:1.Department of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China. ; Xin Wu:1.Department of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China. ; Wei Tan:1.Department of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China. ; Jinpeng Yan:1.Department of Cell Biology, School of Life Sciences, Central South University, Changsha, Hunan, 410017, P. R. China. ; Jun Zhou:1.Medical Science Research Center, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China. ; Shijie Chen:1.Department of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China. ; Jinglei Miao:1.Department of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China. ; Jun Cheng:1.Department of Spine Surgery, The Third Xiangy

    期刊:Single-Atom Cu Nanozyme-Loaded Bone Scaffolds for Ferroptosis-Synergized Mild Photothermal Therapy in Osteosarcoma Treatment

    DOI:10.1002/adhm.202304595

    影响因子 :10.0

    引用产品: Saos-2 细胞

  • Multi-omics analysis reveals cuproptosis and mitochondria-based signature for assessing prognosis and immune landscape in osteosarcoma (2024-01-05)

    作者:Chenguang Jia:1.Department of Osteonecrosis and Hip Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China. ; 2.Department of Orthopedics, Hebei Chest Hospital, Shijiazhuang, China. ; Mei Liu:1.Molecular Biology Laboratory, Hebei Chest Hospital, Shijiazhuang, China. ; Liming Yao:1.Department of Orthopedics, Hebei Chest Hospital, Shijiazhuang, China. ; Fangchao Zhao:1.Department of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Shuren Liu:1.Department of Orthopedics, Hebei Chest Hospital, Shijiazhuang, China. ; Zhuo Li:1.Department of Orthopedics, Hebei Chest Hospital, Shijiazhuang, China. ; Yongtai Han:1.Department of Osteonecrosis and Hip Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China. ;

    期刊:Multi-omics analysis reveals cuproptosis and mitochondria-based signature for assessing prognosis and immune landscape in osteosarcoma

    DOI:10.3389/fimmu.2023.1280945

    影响因子 :7.3

    引用产品: hFOB 1.19 细胞 ,  HOS 细胞 ,  Saos-2 细胞 ,  143B 细胞

  • Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway (2024-01-08)

    作者:Ziang Zheng:1.Department of Bone and Soft Tissue Repair and Reconstructive Surgery, The Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Dalian, 116000, Liaoning, China. ; Xinghan Zhao:1.Department of Bone and Soft Tissue Repair and Reconstructive Surgery, The Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Dalian, 116000, Liaoning, China. ; Bo Yuan:1.Department of Bone and Soft Tissue Repair and Reconstructive Surgery, The Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Dalian, 116000, Liaoning, China. ; Shan Jiang:1.Department of Bone and Soft Tissue Repair and Reconstructive Surgery, The Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Dalian, 116000, Liaoning, China. ; Rushan Yan:1.Department of Bone and Soft Tissue Repair and Reconstructive Surgery, The Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Dalian, 116000, Liaoning, China. ; Xiaowei Dong:1.Department of Bone a

    期刊:Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway

    DOI:10.1186/s10020-024-00778-y

    影响因子 :5.7

    引用产品: U-2 OS [U2OS] 细胞 ,  Saos-2 细胞 ,  MG-63 细胞

  • Bone-targeting exosome nanoparticles activate Keap1 / Nrf2 / GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells (2023-09-30)

    作者:Wenkai Chen:1.Department of Orthopedic Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. ; 2.Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, Xiamen Key Laboratory of Regeneration Medicine, Organ Transplantation Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. ; Zongguang Li:1.Department of Orthopedic Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. ; 2.Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, Xiamen Key Laboratory of Regeneration Medicine, Organ Transplantation Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. ; Naichun Yu:1.Department of Orthopedic Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. ; 2.Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, Xiamen Key Laboratory of Regeneration Medic

    期刊:Bone-targeting exosome nanoparticles activate Keap1 / Nrf2 / GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells

    DOI:10.1186/s12951-023-02129-1

    影响因子 :10.2

    引用产品: 143B 细胞 ,  MG-63 细胞 ,  Saos-2 细胞 ,  U-2 OS [U2OS] 细胞 ,  人骨髓间充质干细胞

  • Natural Chlorogenic Acid Planted Nanohybrids with Steerable Hyperthermia for Osteosarcoma Suppression and Bone Regeneration (2023-05-11)

    作者:Yu-Ying Yang:1.Department of Pharmacy, Second Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China. ; 2.Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China. ; Yuan Zheng:1.Department of Pharmacy, Second Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China. ; 2.Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China. ; Jun-Jin Liu:1.Department of Pharmacy, Second Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China. ; 2.Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China. ; Zhuang-Peng Chang:1.Department of Pharmacy, Second Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China. ; 2.Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R.

    期刊:Natural Chlorogenic Acid Planted Nanohybrids with Steerable Hyperthermia for Osteosarcoma Suppression and Bone Regeneration

    DOI:10.1002/adhm.202300325

    影响因子 :10.0

    引用产品: Saos-2 细胞 ,  MC3T3-E1 Subclone 24 细胞

  • Osteoporotic bone loss from excess iron accumulation is driven by NOX4-triggered ferroptosis in osteoblasts (2023-02-03)

    作者:Hui Zhang:1.Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China; Department of Orthopaedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China; Osteoporosis Clinical Center, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China. ; Aifei Wang:1.Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China; Osteoporosis Clinical Center, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China; Institute of Osteoporosis Diagnosis and Treatments of Soochow University, Suzhou, 215004, China. ; Guangfei Li:1.Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China; Osteoporosis Clinical Center, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China. ; Qiaocheng Zhai:1.Jiangsu Key Laborat

    期刊:Osteoporotic bone loss from excess iron accumulation is driven by NOX4-triggered ferroptosis in osteoblasts

    DOI:10.1016/j.freeradbiomed.2023.01.026

    影响因子 :7.4

    引用产品: hFOB 1.19 细胞 ,  Saos-2 细胞

  • Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction (2023-12-15)

    作者:Junchao Zhu:1.Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ; Jinghong Yuan:1.Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ; Shahrzad Arya:1.Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. ; Zhi Du:1.Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ; Xijuan Liu:1.Department of Pediatrics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ; Jingyu Jia:1.Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. ;

    期刊:Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction

    DOI:10.3389/fimmu.2023.1265098

    影响因子 :7.3

    引用产品: HOS 细胞 ,  Saos-2 细胞

  • A1BG-AS1 promotes the biological functions of osteosarcoma cells via regulating the microRNA-148a-3p/USP22 axis and stabilizing the expression of SIRT1 through deubiquitinase function (2023-10-03)

    作者:Xiuxin Han:1.Department of Bone and Soft Tissue Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center of Cancer, Tianjin, China. ; Mengfan Yin:1.Department of Bone and Soft Tissue Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center of Cancer, Tianjin, China. ; 2.Department of Orthopedic Surgery, Tianjin Fifth Central Hospital, Tianjin, China. ; Chen Gong:1.General Clinical Research Center, Anhui Wanbei Coal-Electricity Group General Hospital, Suzhou, Anhui, China. ; Chao Zhang:1.Department of Bone and Soft Tissue Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center of

    期刊:A1BG-AS1 promotes the biological functions of osteosarcoma cells via regulating the microRNA-148a-3p/USP22 axis and stabilizing the expression of SIRT1 through deubiquitinase function

    DOI:10.1080/14728222.2023.2263908

    影响因子 :5.8

    引用产品: U-2 OS [U2OS] 细胞 ,  Saos-2 细胞 ,  MG-63 细胞 ,  HOS 细胞 ,  SJSA-1 细胞 ,  hFOB 1.19 细胞 ,  McCoy's 5A 培养基 ,  MEM 培养基 ,  RPMI-1640 培养基 ,  DMEM/F12 培养基

  • ATRX loss suppresses the type I interferon response in sarcoma cells through chromatin remodeling (2023-08-15)

    作者:Xinrui Wang:1.Department of Cell Biology, School of Life Sciences, Anhui Medical University Hefei 230032, Anhui, China. ; Zige Jin:1.Department of Cell Biology, School of Life Sciences, Anhui Medical University Hefei 230032, Anhui, China. ; Shanshan Tang:1.Department of Cell Biology, School of Life Sciences, Anhui Medical University Hefei 230032, Anhui, China. ; Xiyu Huang:1.Department of Cell Biology, School of Life Sciences, Anhui Medical University Hefei 230032, Anhui, China. ; Shanshan Wang:1.Department of Cell Biology, School of Life Sciences, Anhui Medical University Hefei 230032, Anhui, China. ; Xiaohe Ren:1.Department of Cell Biology, School of Life Sciences, Anhui Medical University Hefei 230032, Anhui, China. ; Mafei Xu:1.Department of Cell Biology, School of Life Sciences, Anhui Medical University Hefei 230032, Anhui, China. ;

    期刊:ATRX loss suppresses the type I interferon response in sarcoma cells through chromatin remodeling

    DOI:PMID:37693131

    影响因子 :5.3

    引用产品: HOS 细胞 ,  U-2 OS [U2OS] 细胞 ,  Saos-2 细胞 ,  293T [HEK-293T] 细胞 ,  MG-63 细胞

  • Circular RNA hsa_circ_001350 contributes to osteosarcoma progression by regulating microRNA-578/CCR4-NOT transcription complex and subunit 7/Wnt signaling (2023-06-15)

    作者:Rujin Xu:1.Laboratory Department, Hangzhou Linping First People's Hospital Hangzhou 311400, Zhejiang, P. R. China. ; Xingyuan Ci:1.Laboratory Department, Hangzhou Linping First People's Hospital Hangzhou 311400, Zhejiang, P. R. China. ; Fang He:1.Laboratory Department, Hangzhou Linping First People's Hospital Hangzhou 311400, Zhejiang, P. R. China. ; Yueqin Chen:1.Laboratory Department, Hangzhou Linping First People's Hospital Hangzhou 311400, Zhejiang, P. R. China. ;

    期刊:Circular RNA hsa_circ_001350 contributes to osteosarcoma progression by regulating microRNA-578/CCR4-NOT transcription complex and subunit 7/Wnt signaling

    DOI:PMID:37424831

    影响因子 :5.3

    引用产品: hFOB 1.19 细胞 ,  U-2 OS [U2OS] 细胞 ,  HOS 细胞 ,  Saos-2 细胞 ,  MG-63 细胞

  • HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway (2023-07-30)

    作者:Ziyuan Tong:1.Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, People's Republic of China. ; Yuan Shen:1.Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, People's Republic of China. ; Quan Yuan:1.Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, People's Republic of China. ; Honghao Yu:1.Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, People's Republic of China. Electronic address: yhhspine2022@163.com. ;

    期刊:HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway

    DOI:10.1016/j.bbamcr.2023.119553

    影响因子 :5.1

    引用产品: HOS 细胞 ,  Saos-2 细胞 ,  SW 1353 细胞 ,  McCoy's 5A 培养基

  • RING finger gene 180 inhibits osteosarcoma progression through regulating chromobox homolog 4 ubiquitination (2023-04-24)

    作者:Qirui Zhao:1.Department of Orthopedic Joint and Sports Medicine Ward, The First Clinical Hospital affiliated to Harbin Medical University, Harbin, Heilongjiang, China. ; Ning Liu:1.Department of Orthopedic Joint and Sports Medicine Ward, The First Clinical Hospital affiliated to Harbin Medical University, Harbin, Heilongjiang, China. ; Tongtong Xu:1.Major of Nursing, China Medical University, Shenyang, Liaoning, China. ; Keguan Song:1.Department of Orthopedic Joint and Sports Medicine Ward, The First Clinical Hospital affiliated to Harbin Medical University, Harbin, Heilongjiang, China. ;

    期刊:RING finger gene 180 inhibits osteosarcoma progression through regulating chromobox homolog 4 ubiquitination

    DOI:10.1080/15384101.2023.2205201

    影响因子 :4.3

    引用产品: 293T [HEK-293T] 细胞 ,  hFOB 1.19 细胞 ,  MNNG/HOS Cl #5 [R-1059-D] 细胞 ,  Saos-2 细胞 ,  MG-63 细胞 ,  U-2 OS [U2OS] 细胞

  • hsa_circ_0020378 regulating miR-339-3p/COL1A1 promotes osteosarcoma progression (2023-11-18)

    作者:Liang Liu:1.Department of Spinal Surgery, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Hubei, China. ; 2.Department of molecular therapy of cancer, Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Huangshi, Hubei, China. ; Wenze Huang:1.Department of Spinal Surgery, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Hubei, China. ; 2.Department of molecular therapy of cancer, Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Huangshi, Hubei, China. ;

    期刊:hsa_circ_0020378 regulating miR-339-3p/COL1A1 promotes osteosarcoma progression

    DOI:10.1080/15384047.2023.2274120

    影响因子 :3.6

    引用产品: hFOB 1.19 细胞 ,  HOS 细胞 ,  Saos-2 细胞 ,  SW 1353 细胞 ,  Leibovitz's L-15 培养基 ,  McCoy's 5A完全培养基 (含10%FBS) ,  MEM 培养基 ,  DMEM/F12 培养基 ,  青霉素-链霉素溶液 (双抗),100× ,  特级胎牛血清

  • Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy (2023-11-22)

    作者:Chenyang Meng:1.Department of Orthopedic Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China. ; Yun Yang:1.Department of Orthopedic Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China. ; Wei Feng:1.Department of Orthopedic Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China. ; Penglei Ma:1.Department of Anesthesiology, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China. 39818135@qq.com. ; Rui Bai:1.Department of Orthopedic Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China. bairuiandaiqing@126.com. ;

    期刊:Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy

    DOI:10.1186/s13018-023-04338-8

    影响因子 :2.6

    引用产品: MG-63 细胞 ,  HOS 细胞 ,  U-2 OS [U2OS] 细胞 ,  Saos-2 细胞

  • DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway (2023-02-27)

    作者:Mingming Yang:1.Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, No. 1 YouYi Road, Yuan Jia Gang, Yu Zhong District, Chongqing, 400016, People's Republic of China. yangmm@hospital.cqmu.edu.cn. ; Hang Zhang:1.Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, No. 1 YouYi Road, Yuan Jia Gang, Yu Zhong District, Chongqing, 400016, People's Republic of China. ; Shichang Gao:1.Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, No. 1 YouYi Road, Yuan Jia Gang, Yu Zhong District, Chongqing, 400016, People's Republic of China. ; Wei Huang:1.Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, No. 1 YouYi Road, Yuan Jia Gang, Yu Zhong District, Chongqing, 400016, People's Republic of China. ;

    期刊:DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway

    DOI:10.1186/s13018-023-03572-4

    影响因子 :2.6

    引用产品: hFOB 1.19 细胞 ,  U-2 OS [U2OS] 细胞 ,  Saos-2 细胞 ,  MG-63 细胞

  • Developing a Versatile Multiscale Therapeutic Platform for Osteosarcoma Synergistic Photothermo-Chemotherapy with Effective Osteogenicity and Antibacterial Capability (2022-09-20)

    作者:Yunlong Ma:1.Laser Micro/Nano-Fabrication Laboratory, School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081, P. R. China. ; 2.Beijing Institute of Technology Chongqing Innovation Center, Chongqing 401120, P. R. China. ; 3.Yangtze Delta Region Academy of Beijing Institute of Technology, Jiaxing 314019, P. R. China. ; Lan Jiang:1.Laser Micro/Nano-Fabrication Laboratory, School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081, P. R. China. ; 2.Beijing Institute of Technology Chongqing Innovation Center, Chongqing 401120, P. R. China. ; 3.Yangtze Delta Region Academy of Beijing Institute of Technology, Jiaxing 314019, P. R. China. ; Jie Hu:1.Laser Micro/Nano-Fabrication Laboratory, School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081, P. R. China. ; 2.Beijing Institute of Technology Chongqing Innovation Center, Chongqing 401120, P. R. China. ; 3.Yangtze Delta Region Academy of Beijing Institute of Technolo

    期刊:Developing a Versatile Multiscale Therapeutic Platform for Osteosarcoma Synergistic Photothermo-Chemotherapy with Effective Osteogenicity and Antibacterial Capability

    DOI:10.1021/acsami.2c10772

    影响因子 :10.4

    引用产品: Saos-2 细胞 ,  MDA-MB-231 细胞

  • MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm (2003-01-20)

    作者:Lifang Hu:1.Laboratory for Bone Metabolism, Key Laboratory for Space Biosciences and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China. ; 2.Xi'an Key Laboratory of Special Medicine and Health Engineering, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China. ; 3.Research Center for Special Medicine and Health Systems Engineering, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China. ; 4.NPU-UAB Joint Laboratory for Bone Metabolism, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China. ; Chong Yin:1.Laboratory for Bone Metabolism, Key Laboratory for Space Biosciences and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China. ; 2.Xi'an Key Laboratory of Special Medicine and Health Engineering, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China. ; 3.Research C

    期刊:MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm

    DOI:10.1038/s41418-021-00744-9

    影响因子 :12.4

    引用产品: Saos-2 细胞 ,  McCoy's 5A 培养基

  • lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression (2008-01-20)

    作者:Lei Ding:1.Department of Rehabilitation, The Second Hospital of Jilin University, Changchun 130000, Jilin, China. ; Taiyuan Liu:1.Department of Breast Surgery, The Second Hospital of Jilin University, Changchun 130000, Jilin, China. ; 2.Department of Breast Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, Liaoning, China. ; Yuan Qu:1.Department of Spine Surgery, The Second Hospital of Jilin University, Changchun 130000, Jilin, China. ; Zhichen Kang:1.Department of Rehabilitation, The Second Hospital of Jilin University, Changchun 130000, Jilin, China. ; Lixin Guo:1.Department of Rehabilitation, The Second Hospital of Jilin University, Changchun 130000, Jilin, China. ; Haina Zhang:1.Department of Rehabilitation, The Second Hospital of Jilin University, Changchun 130000, Jilin, China. ; Junjie Jiang:1.Department of Rehabilitation, The Second Hospital of Jilin University, Changchun 130000, Jilin, China. ; Fuling Qu:1.Department of Rehabilitation,

    期刊:lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression

    DOI:10.1016/j.omtn.2021.08.022

    影响因子 :8.8

    引用产品: Saos-2 细胞 ,  MG-63 细胞 ,  U-2 OS [U2OS] 细胞 ,  HOS 细胞

  • Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells (2010-01-20)

    作者:Rui Zhang:1.Orthopedic Oncology Institute, Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. ; Huan Wang:1.Orthopedic Oncology Institute, Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. ; Erliang Li:1.Orthopedic Oncology Institute, Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. ; Yonghong Wu:1.Orthopedic Oncology Institute, Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. ; Yanhua Wen:1.Orthopedic Oncology Institute, Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. ; Chenyu Li:1.Orthopedic Oncology Institute, Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. ; Bo Liao:1.Orthopedic Oncology Institute, Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medica

    期刊:Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells

    DOI:10.1186/s12935-021-02286-z

    影响因子 :5.8

    引用产品: Saos-2 细胞

  • Down-regulation of PRR11 affects the proliferation, migration and invasion of osteosarcoma by inhibiting the Wnt/β-catenin pathway (2009-01-20)

    作者:Ke Li:1.Orthopedic Center, First Affiliated Hospital, School of Medicine, Shihezi University, No.107 North 2nd Road, Shihezi, Xinjiang 832008, P. R. China. ; Hongtao Yu:1.Orthopedic Center, First Affiliated Hospital, School of Medicine, Shihezi University, No.107 North 2nd Road, Shihezi, Xinjiang 832008, P. R. China. ; Chunbing Zhao:1.Department of Pharmacy, First Affiliated Hospital, School of Medicine, Shihezi University, No.107 North 2nd Road, Shihezi, Xinjiang 832008, P. R. China. ; Jing Li:1.Orthopedic Center, First Affiliated Hospital, School of Medicine, Shihezi University, No.107 North 2nd Road, Shihezi, Xinjiang 832008, P. R. China. ; Rui Tan:1.Orthopedic Center, First Affiliated Hospital, School of Medicine, Shihezi University, No.107 North 2nd Road, Shihezi, Xinjiang 832008, P. R. China. ; Lei Chen:1.Orthopedic Center, First Affiliated Hospital, School of Medicine, Shihezi University, No.107 North 2nd Road, Shihezi, Xinjiang 832008, P. R. China. ;

    期刊:Down-regulation of PRR11 affects the proliferation, migration and invasion of osteosarcoma by inhibiting the Wnt/β-catenin pathway

    DOI:10.7150/jca.62491

    影响因子 :3.9

    引用产品: Saos-2 细胞 ,  MG-63 细胞 ,  U-2 OS [U2OS] 细胞 ,  hFOB 1.19 细胞

  • Schisandrin B Inhibits Cell Viability and Migration, and Induces Cell Apoptosis by circ_0009112/miR-708-5p Axis Through PI3K/AKT Pathway in Osteosarcoma (2012-01-20)

    作者:Bing Wang:1.Department of Orthopaedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Xiaowei Wang:1.Department of Orthopaedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Xing Tong:1.Department of Orthopaedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Yingang Zhang:1.Department of Orthopaedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ;

    期刊:Schisandrin B Inhibits Cell Viability and Migration, and Induces Cell Apoptosis by circ_0009112/miR-708-5p Axis Through PI3K/AKT Pathway in Osteosarcoma

    DOI:10.3389/fgene.2020.588670

    影响因子 :3.7

    引用产品: U-2 OS [U2OS] 细胞 ,  Saos-2 细胞 ,  hFOB 1.19 细胞

  • Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner (2012-01-20)

    作者:Tehasi Wang:1.Graduate School, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China. ; Chengguang Zhang:1.Graduate School, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China. ; Shuren Wang:1.Department of Tramotology and Orthopedics, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, No. 26 Heping Road, Xiangfang District, Harbin, 150040, Heilongjiang, China. wsr696969@163.com. ;

    期刊:Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner

    DOI:10.1186/s13018-021-02868-7

    影响因子 :2.6

    引用产品: MG-63 细胞 ,  Saos-2 细胞

  • circATP2A2 promotes osteosarcoma progression by upregulating MYH9 (2011-01-20)

    作者:Xin Cao:1.Department of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China. ; Xianfeng Meng:1.Department of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China. ; Peng Fu:1.Department of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China. ; Lin Wu:1.Department of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China. ; Zhen Yang:1.Department of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China. ; Huijin Chen:1.Department of Clinical Laboratory, Shengli Oilfield Central Hospital, No. 31, Jinan Road, Dongying, 257000, Shandong, China. ;

    期刊:circATP2A2 promotes osteosarcoma progression by upregulating MYH9

    DOI:10.1515/med-2021-0370

    影响因子 :2.1

    引用产品: U-2 OS [U2OS] 细胞 ,  HOS 细胞 ,  Saos-2 细胞 ,  特级胎牛血清 ,  DMEM/F12 培养基 ,  hFOB 1.19 细胞

  • ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p (2003-00-20)

    作者:Quan Yuan:1.1Department of Orthopedics, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang, 110004 People's Republic of China. ; Honghao Yu:1.1Department of Orthopedics, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang, 110004 People's Republic of China. ; Jianhua Chen:1.1Department of Orthopedics, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang, 110004 People's Republic of China. ; Xiaoyu Song:1.2Institute of Translational Medicine, China Medical University, Shenyang, 110122 People's Republic of China. ; Li Sun:1.3Department of Nephrology, The First Hospital of China Medical University, Shenyang, 110001 People's Republic of China. ;

    期刊:ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p

    DOI:10.1186/s12935-020-01174-2

    影响因子 :5.8

    引用产品: Saos-2 细胞 ,  SW 1353 细胞 ,  HOS 细胞 ,  McCoy's 5A 培养基

  • Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells (2002-00-20)

    作者:Quan Yuan:1.Department of Orthopedic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China. ; Honghao Yu:1.Department of Orthopedic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China. ; Jianhua Chen:1.Department of Orthopedic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China. ; Xiaoyu Song:1.Institute of Translational Medicine, China Medical University, Shenyang 110122, People's Republic of China. ; Li Sun:1.Department of Nephrology, The First Hospital of China Medical University, Shenyang 110001, People's Republic of China. ;

    期刊:Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells

    DOI:10.2147/OTT.S232718

    影响因子 :4.0

    引用产品: Saos-2 细胞 ,  HOS 细胞

  • Long Non-Coding RNA OIP5-AS1 Knockdown Enhances CDDP Sensitivity in Osteosarcoma via miR-377-3p/FOSL2 Axis (2005-00-20)

    作者:Ling Liu:1.Department of Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, Henan, People's Republic of China. ; Shuya Wang:1.Department of Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, Henan, People's Republic of China. ;

    期刊:Long Non-Coding RNA OIP5-AS1 Knockdown Enhances CDDP Sensitivity in Osteosarcoma via miR-377-3p/FOSL2 Axis

    DOI:10.2147/OTT.S232918

    影响因子 :4.0

    引用产品: MG-63 细胞 ,  Saos-2 细胞

  • Sirt1 modulates H3 phosphorylation and facilitates osteosarcoma cell autophagy (2008-09-20)

    作者:Hongliang Ying:1.a Department of Orthopaedics, China-Japan Union Hospital of Jilin University , Changchun , China. ; Boda Ying:1.b Department of Joint Surgery of Orthopaedic Center, The Second Hospital of Jilin University , Changchun , China. ; Jinrui Zhang:1.a Department of Orthopaedics, China-Japan Union Hospital of Jilin University , Changchun , China. ; Daliang Kong:1.a Department of Orthopaedics, China-Japan Union Hospital of Jilin University , Changchun , China. ;

    期刊:Sirt1 modulates H3 phosphorylation and facilitates osteosarcoma cell autophagy

    DOI:10.1080/21691401.2019.1648280

    影响因子 :5.8

    引用产品: Saos-2 细胞 ,  MG-63 细胞 ,  HOS 细胞

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