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产品概述
| 名称 | KYSE-150 (人食管鳞癌细胞) (STR鉴定正确) |
| 别称 | KYSE 150; KYSE150; Kyse150; KY150 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:5 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | Established from the poorly differentiated esophageal squamous cell carcinoma resected from upper (cervical) esophagus of a 49-year-old Japanese woman after receiving radiotherapy (tumor was invading contiguous structures); described as carrying amplified oncogenes, c-erb-B (8x) and cyclin D1 (4x) and producing tumors in nude mice. |
| 年龄（性别） | 女性；49岁 |
| 组织来源 | 食管 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 食管癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | 13.7 hours (PubMed=1728357); 23 hours (PubMed=25984343); <25 hours, less when serum amount is increased (DSMZ) |
| 致瘤性 | Yes, in nude mice |
| 保藏机构 | DSMZ; ACC-375 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12,13 D2S1338 25 D3S1358 15,16 D5S818 12,13 D7S820 10,11 D8S1179 10,15 D13S317 8,11 D16S539 9,11 D18S51 14 D19S433 15,15.2 D21S11 30,31 FGA 21,24 PentaD 10 PentaE 12,18 TH01 7,9 TPOX 8 vWA 16,17 D6S1043 18,20 D12S391 19,22 D2S441 10,11 -
STR鉴定图
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参考文献
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N6-methyladenosine-mediated upregulation of LNCAROD confers radioresistance in esophageal squamous cell carcinoma through stabilizing PARP1 (2024-10-05)
期刊：Clinical and Translational Medicine
影响因子 ：7.9
引用产品： KYSE-30 细胞 , KYSE-150 细胞 , TE-1 细胞 , KYSE-410 细胞
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Lymphatic endothelial cell-mediated accumulation of CD177+Treg cells suppresses antitumor immunity in human esophageal squamous cell carcinoma (2024-03-20)
期刊：OncoImmunology
DOI：10.1080/2162402X.2024.2327692
影响因子 ：7.2
引用产品： KYSE-150 细胞 , 人淋巴管内皮细胞 , 多聚-L-赖氨酸溶液 (10×) , 人淋巴管内皮细胞完全培养基
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DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3 (2024-12-31)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05960-8
影响因子 ：6.1
引用产品： KYSE-150 细胞
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Pan-cancer analysis shows that BCAP31 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types (2024-12-16)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1507375
影响因子 ：5.7
引用产品： KYSE-150 细胞
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SIRT2-mediated deacetylation of ACLY promotes the progression of oesophageal squamous cell carcinoma (2024-03-01)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：5.3
引用产品： KYSE-150 细胞
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EIF4A3-mediated oncogenic circRNA hsa_circ_0001165 advances esophageal squamous cell carcinoma progression through the miR-381-3p/TNS3 pathway (2024-10-09)
期刊：CELL BIOLOGY AND TOXICOLOGY
DOI：10.1007/s10565-024-09927-9
影响因子 ：5.3
引用产品： KYSE-150 细胞 , 293 [HEK-293] 细胞 , Eca-109 细胞 , TE-1 细胞 , KYSE-510 细胞 , KYSE-30 细胞
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Synthesis and Biological Evaluation of Novel Furopyridone Derivatives as Potent Cytotoxic Agents against Esophageal Cancer (2024-09-05)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：4.9
引用产品： KYSE70 细胞 , KYSE-150 细胞
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Artesunate-loaded solid lipid nanoparticles resist esophageal squamous cell carcinoma by inducing Ferroptosis through inhibiting the AKT/mTOR signaling (2024-02-16)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111108
影响因子 ：4.8
引用产品： KYSE-150 细胞 , KYSE-30 细胞 , 人食管上皮细胞 , RPMI-1640完全培养基 (含10%FBS）
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Alkannin Induces G2/M-Phase Arrest, Apoptosis, and Inhibition of Invasion by Targeting GSK3β in Esophageal Squamous Cell Carcinoma (2024-11-24)
期刊：Drug Design Development and Therapy
影响因子 ：4.7
引用产品： Eca-109 细胞 , KYSE-150 细胞
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Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1 (2024-02-14)
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23696
影响因子 ：4.6
引用产品： KYSE-150 细胞 , KYSE-30 细胞 , KYSE-410 细胞
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Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma (2024-06-05)
期刊：iScience
DOI：10.1016/j.isci.2024.110188
影响因子 ：4.6
引用产品： KYSE-30 细胞 , KYSE-150 细胞
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Overexpression of YAP confers radioresistance to esophageal cancer by altering the tumor microenvironment (2024-02-20)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： KYSE-150 细胞
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Single-cell transcriptome sequencing analysis reveals intra-tumor heterogeneity in esophageal squamous cell carcinoma (2024-04-04)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： TE-1 细胞 , KYSE-150 细胞
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Arntl-induced upregulation of DUSP1 inhibits tumor progression in esophageal squamous cell carcinoma by inactivating ERK signaling (2024-09-28)
期刊：CANCER BIOLOGY & THERAPY
DOI：10.1080/15384047.2024.2408042
影响因子 ：4.4
引用产品： KYSE-150 细胞 , TE-1 细胞
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FABP6 serves as a new therapeutic target in esophageal tumor (2024-01-25)
期刊：Aging-US
影响因子 ：3.9
引用产品： KYSE-30 细胞 , KYSE-150 细胞 , Eca-109 细胞 , HET1A 细胞
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CXCR4 up-regulation mediated by USP1 deubiquitination promotes the tumorigenesis and immune escape in esophageal squamous-cell carcinoma (2024-10-23)
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 ：3.2
引用产品： KYSE-180 细胞 , KYSE-150 细胞 , KYSE-30 细胞 , TE-1 细胞 , 人食管上皮细胞
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Exosome-transported of circ_0081069 induces SPIN1 production by binding to miR-195-5p to inhibit radiosensitivity in esophageal squamous cell carcinoma (2024-02-01)
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 ：3.2
引用产品： KYSE-150 细胞 , KYSE-30 细胞
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Highly Expressed Z-DNA Binding Protein 1 in Esophageal Cancer Promotes Tumor Growth (2024-03-20)
期刊：DIGESTIVE DISEASES AND SCIENCES
DOI：10.1007/s10620-024-08375-z
影响因子 ：3.1
引用产品： KYSE-150 细胞 , KYSE-30 细胞
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The anti-tumor activity of tangeretin in esophageal squamous cell carcinoma by inhibiting GLI2-mediated transcription of GPNMB (2024-06-26)
期刊：PLoS One
DOI：10.1371/journal.pone.0291531
影响因子 ：2.9
引用产品： 293T [HEK-293T] 细胞 , KYSE-150 细胞 , TE-1 细胞
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Zuojin Pill inhibits the proliferation of esophageal cancer cells by inducing ROS production and apoptosis via regulation of PI3K/Akt signalling (2024-06-14)
期刊：Journal of Taibah University for Science
DOI：10.1080/16583655.2024.2361991
影响因子 ：2.8
引用产品： KYSE-150 细胞
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LncRNA NONHSAT227443.1 Confers Esophageal Squamous Cell Carcinoma Chemotherapy Resistance by Activating PI3K/AKT Signaling via Targeting MRTFB (2024-08-16)
期刊：TECHNOLOGY IN CANCER RESEARCH & TREATMENT
影响因子 ：2.7
引用产品： TE-1 细胞 , KYSE-150 细胞 , TE-12 细胞 , STR鉴定
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Involvement of circRNA Regulators MBNL1 and QKI in the Progression of Esophageal Squamous Cell Carcinoma (2024-05-20)
期刊：Cancer Control
影响因子 ：2.6
引用产品： KYSE-150 细胞
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circ-TTC17 Promotes Esophagus Squamous Cell Carcinoma Cell Growth, Metastasis, and Inhibits Autophagy-Mediated Radiosensitivity Through miR-145-5p/SIRT1 Axis (2024-12-02)
期刊：Thoracic Cancer
影响因子 ：2.3
引用产品： TE-1 细胞 , KYSE-150 细胞 , KYSE-180 细胞 , KYSE-30 细胞 , 人食管上皮细胞
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USP8-Dependent Family Tyrosine Kinase Promotes the Malignant Progression of Esophageal Squamous Cell Carcinoma by Upregulating Protein Tyrosine Kinase 2 Expression (2024-12-19)
期刊：Thoracic Cancer
影响因子 ：2.3
引用产品： KYSE-30 细胞 , KYSE-180 细胞 , TE-1 细胞 , KYSE-150 细胞 , 人食管上皮细胞
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Circular RNA circCHSY1 silencing inhibits the malignant progression of esophageal squamous cell carcinoma (2024-03-21)
期刊：Discover Oncology
DOI：10.1007/s12672-024-00935-z
影响因子 ：2.2
引用产品： TE-1 细胞 , Eca-109 细胞 , KYSE-150 细胞 , 人脐静脉内皮细胞 , 青霉素-链霉素溶液 (双抗)，100×
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XRCC2 knockdown effectively sensitizes esophageal cancer to albumin-paclitaxel in vitro and in vivo (2024-07-24)
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-024-10885-4
影响因子 ：2.1
引用产品： DMEM高糖 培养基 , RPMI-1640 培养基 , 特级胎牛血清 , KYSE-150 细胞 , Eca-109 细胞 , 青霉素-链霉素溶液（双抗），100× , KYSE-30 细胞
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Ginsenoside 20(S)-Rg3 Hinders Esophageal Squamous Cell Carcinoma Cells Malignant Behaviors by miR-210-3p/B4GALT5 Axis (2024-10-18)
期刊：CELL BIOCHEMISTRY AND BIOPHYSICS
DOI：10.1007/s12013-024-01566-5
影响因子 ：1.8
引用产品： KYSE-150 细胞 , Eca-109 细胞
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Circ_0000277 promotes the malignant progression of oesophageal squamous cell carcinoma through miR-1294-dependent regulation of DVL3 (2024-04-22)
期刊：Molecular & Cellular Toxicology
DOI：10.1007/s13273-024-00443-9
影响因子 ：1.7
引用产品： MTT溶液（5 mg/mL） , 人食管上皮细胞 , KYSE-150 细胞
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Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma (2023-12-14)
期刊：EBioMedicine
DOI：10.1016/j.ebiom.2023.104920
影响因子 ：11.1
引用产品： KYSE-410 细胞 , KYSE-30 细胞 , KYSE-510 细胞 , KYSE450 细胞 , KYSE-150 细胞 , RPMI-1640 培养基 , 特级胎牛血清
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The AEG-1-USP10-PARP1 axis confers radioresistance in esophageal squamous cell carcinoma via facilitating homologous recombination-dependent DNA damage repair (2023-10-12)
期刊：CANCER LETTERS
DOI：10.1016/j.canlet.2023.216440
影响因子 ：9.7
引用产品： KYSE-150 细胞 , Eca-109 细胞 , KYSE-410 细胞 , KYSE-30 细胞 , TE-1 细胞
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Designing Nd-doped bismuth selenide nanosheets with boosted photothermal conversion for imaging guided cancer therapy (2023-02-28)
期刊：MATERIALS & DESIGN
DOI：10.1016/j.matdes.2023.111801
影响因子 ：8.4
引用产品： KYSE-150 细胞
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Brusatol induces ferroptosis in oesophageal squamous cell carcinoma by repressing GSH synthesis and increasing the labile iron pool via inhibition of the NRF2 pathway (2023-09-22)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.115567
影响因子 ：7.5
引用产品： KYSE-150 细胞
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Circular RNA circ‐TNRC6B inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by regulating the miR‐452‐5p/DAG1 axis (2023-04-16)
期刊：Molecular Oncology
影响因子 ：6.6
引用产品： TE-1 细胞 , KYSE-30 细胞 , KYSE-150 细胞 , KYSE-170 细胞
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Long noncoding RNAs with peptide-encoding potential identified in esophageal squamous cell carcinoma: KDM4A-AS1-encoded peptide weakens cancer cell viability and migratory capacity (2023-03-25)
期刊：Molecular Oncology
影响因子 ：6.6
引用产品： KYSE-150 细胞 , TE-1 细胞 , 293T [HEK-293T] 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100× , DMEM高糖 培养基
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ZPR1 is an immunodiagnostic biomarker and promotes tumor progression in esophageal squamous cell carcinoma (2023-11-14)
期刊：CANCER SCIENCE
影响因子 ：5.7
引用产品： KYSE-150 细胞 , Eca-109 细胞 , TE-1 细胞 , 人食管上皮细胞
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Methyltransferase-like 3 facilitates the stem cell properties of esophageal cancer by upregulating Patched homolog 1 via N6-methyladenosine methylation (2023-08-14)
期刊：AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
DOI：10.1152/ajpcell.00136.2023
影响因子 ：5.5
引用产品： TE-1 细胞 , KYSE-30 细胞 , KYSE-150 细胞 , KYSE-410 细胞 , RPMI-1640 培养基
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SH2D4A inhibits esophageal squamous cell carcinoma progression through FAK/PI3K/AKT signaling pathway (2023-12-02)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110997
影响因子 ：4.8
引用产品： TE-1 细胞 , TE-10 细胞 , KYSE-150 细胞 , KYSE-510 细胞
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Potential ‘anti-cancer’ effects of esketamine on proliferation, apoptosis, migration and invasion in esophageal squamous carcinoma cells (2023-11-15)
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-023-01511-x
影响因子 ：4.2
引用产品： KYSE-30 细胞 , KYSE-150 细胞
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Selenide Heterostructure Nanosheets with Efficient Near-Infrared Photothermal Conversion for Therapy (2023-03-03)
期刊：ACS Omega
影响因子 ：4.1
引用产品： KYSE-150 细胞
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Irradiation Induces Gasdermin E-Triggered Tumor Immunity to Inhibit Esophageal Carcinoma Cell Survival (2023-11-29)
期刊：ACS Omega
影响因子 ：4.1
引用产品： Eca-109 细胞 , KYSE-150 细胞 , RPMI-1640 培养基 , 青霉素-链霉素溶液 (双抗)，100× , Ham's F-12 培养基
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Upregulation of miR-194-5p or silencing of PRC1 enhances radiotherapy sensitivity in esophageal squamous carcinoma cells (2023-11-13)
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e22282
影响因子 ：4.0
引用产品： KYSE-150 细胞
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LincRNA-P21 knockdown facilitates esophageal squamous cell carcinoma cell progression by upregulating cadherin 5 via YTH domain containing 1: The role of lncRNA-P21/YTHDC1/CDH5 axis in ESCC (2023-09-27)
期刊：ACTA BIOCHIMICA ET BIOPHYSICA SINICA
影响因子 ：3.7
引用产品： 青霉素-链霉素溶液（双抗），100× , Ham's F-12 培养基 , TE-1 细胞 , KYSE-150 细胞 , RPMI-1640 培养基
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Phosphorylation of AKT by lysyl oxidase-like 2 activates the PI3K/AKT signaling pathway to promote proliferation, invasion and metastasis in esophageal squamous carcinoma (2023-03-30)
期刊：Clinical & Translational Oncology
DOI：10.1007/s12094-023-03133-5
影响因子 ：3.4
引用产品： Eca-109 细胞 , KYSE-150 细胞
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PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma (2023-10-04)
期刊：Oncology Letters
影响因子 ：2.9
引用产品： TE-1 细胞 , KYSE-30 细胞 , KYSE-150 细胞 , KYSE170 细胞
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LOXL2 promotes tumor proliferation and metastasis by FAK/Src signaling in esophageal squamous cell carcinoma (2023-04-06)
期刊：ELECTRONIC JOURNAL OF BIOTECHNOLOGY
DOI：10.1016/j.ejbt.2023.01.002
影响因子 ：2.7
引用产品： Eca-109 细胞 , KYSE-150 细胞
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Inhibition of p62-Keap1-Nrf2 Pathway Activation by Realgar Promotes the Inhibition of Esophageal Cancer Cell Proliferation, Migration, and Ferroptosis (2023-01-19)
期刊：Current Drug Delivery
DOI：10.2174/1567201820666221226105655
影响因子 ：2.4
引用产品： Eca-109 细胞 , KYSE-150 细胞 , 人食管上皮细胞
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Bridging Integrator 3 (BIN3) Downregulation Predicts a Poor Prognosis in Patients with Esophagus Carcinoma: A Study based on TCGA Data (2023-09-01)
期刊：COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
DOI：10.2174/1386207326666221205101815
影响因子 ：1.8
引用产品： TE-1 细胞 , KYSE-30 细胞 , KYSE-150 细胞
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Circ_0024108 promotes the progression of esophageal cancer cells (2023-02-09)
期刊：General Thoracic and Cardiovascular Surgery
DOI：10.1007/s11748-023-01909-8
影响因子 ：1.2
引用产品： Eca-109 细胞 , KYSE-150 细胞 , KYSE450 细胞 , KYSE-410 细胞 , 人食管上皮细胞
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CircGFPT1 regulates the growth and apoptosis of esophageal squamous cell carcinoma through miR-142-5p/HAX1 axis (2023-07-16)
期刊：General Thoracic and Cardiovascular Surgery
DOI：10.1007/s11748-023-01955-2
影响因子 ：1.2
引用产品： KYSE-150 细胞 , 人食管上皮细胞
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The Biological Role of lncRNA linc01816 in Esophageal Squamous Cell Carcinoma and Its Correlation with Prognosis (2023-12-10)
期刊：RUSSIAN JOURNAL OF GENETICS
影响因子 ：0.6
引用产品： KYSE-150 细胞 , Eca-109 细胞 , YES-2 细胞 , TE-1 细胞
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circCYP24A1 facilitates esophageal squamous cell carcinoma progression through binding PKM2 to regulate NF-κB-induced CCL5 secretion (2022-12-13)
期刊：Molecular Cancer
DOI：10.1186/s12943-022-01686-7
影响因子 ：41.4
引用产品： TE-1 细胞 , KYSE-30 细胞 , KYSE-150 细胞 , KYSE170 细胞
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Construction and investigation of β3GNT2-associated regulatory network in esophageal carcinoma (2022-01-24)
期刊：Cellular & Molecular Biology Letters
DOI：10.1186/s11658-022-00306-y
影响因子 ：8.3
引用产品： TE-1 细胞 , KYSE-150 细胞 , KYSE-410 细胞
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Long non-coding RNA NCK1-AS1 functions as a ceRNA to regulate cell viability and invasion in esophageal squamous cell carcinoma via microRNA-133b/ENPEP axis (2022-11-22)
期刊：CELL CYCLE
DOI：10.1080/15384101.2022.2138416
影响因子 ：5.2
引用产品： KYSE-150 细胞 , TE-10 细胞
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Tumor-derived extracellular vesicles confer 5-fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery (2022-10-14)
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23469
影响因子 ：5.1
引用产品： KYSE-150 细胞 , TE-1 细胞
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DNA methyltransferase 3 beta regulates promoter methylation of microRNA-149 to augment esophageal squamous cell carcinoma development through the ring finger protein 2/Wnt/β-catenin axis (2022-02-06)
期刊：Bioengineered
DOI：10.1080/21655979.2022.2031411
影响因子 ：4.9
引用产品： TE-1 细胞 , KYSE-150 细胞 , 293T [HEK-293T] 细胞
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circPOLR1C Promotes the Development of Esophageal Cancer by Adsorbing miR-361-3p and Regulating Cancer Cell Apoptosis and Metastasis (2022-12-23)
期刊：Journal of Oncology
影响因子 ：4.5
引用产品： KYSE-30 细胞 , KYSE-150 细胞 , RPMI-1640 培养基 , Ham's F-12 培养基 , 青霉素-链霉素溶液 (双抗)，100× , Annexin V-FITC/ PI荧光双染细胞凋亡检测试剂盒
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CircCDR1 sponges miR-1290 to regulate cell proliferation, migration, invasion, and apoptosis in esophageal squamous cell cancer (2022-03-15)
期刊：Cell Cycle
DOI：10.1080/15384101.2022.2050645
影响因子 ：4.3
引用产品： KYSE-150 细胞 , KYSE-30 细胞
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β-Asarone suppresses TGF-β/Smad signaling to reduce the invasive properties in esophageal squamous cancer cells (2022-09-30)
期刊：MEDICAL ONCOLOGY
DOI：10.1007/s12032-022-01847-0
影响因子 ：3.7
引用产品： KYSE-410 细胞 , KYSE-150 细胞
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Therapeutic benefits of niraparib tosylate as radio sensitizer in esophageal squamous cell carcinoma: an in vivo and in vitro preclinical study (2022-04-01)
期刊：Clinical & Translational Oncology
DOI：10.1007/s12094-022-02818-7
影响因子 ：3.4
引用产品： KYSE-30 细胞 , KYSE-150 细胞
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Exploring the Mechanism of Realgar against Esophageal Cancer Based on Ferroptosis Induced by ROS-ASK1-p38 MAPK Signaling Pathway (2022-09-12)
期刊：Evidence-based Complementary and Alternative Medicine
影响因子 ：2.7
引用产品： Eca-109 细胞 , KYSE-150 细胞 , 人食管上皮细胞
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