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产品概述
名称 | SW480 [SW-480] (人结肠癌细胞) (STR鉴定正确) |
别称 | SW-480; SW 480; SW480E |
种属 | 人类 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,100%, 温度:37℃
|
培养方案B(可选) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
注意事项 | 1. 该细胞推荐使用Leibovitz's L-15培养基进行培养,Leibovitz's L-15不可以通入二氧化碳,会产生细胞毒性; 2. 该细胞不建议更换为DMEM培养,圆形较多,效果不好。 |
背景描述 | SW480 [SW-480]细胞源自原位直肠腺癌,和SW620细胞源自同一病人一年后的淋巴结转移。CSAp和直肠抗体3阴性;角蛋白免疫过氧化物酶染色阳性。p53基因第273位密码子的G→A突变引起Arg→His替代,309位密码子的C→T突变导致Pro→Ser替代。细胞p53蛋白表达水平提高,癌基因c-myc、K-ras、H-ras、N-ras、myb、sis和fos的表达呈阳性,癌基因N-myc的表达未做检测。SW480 [SW-480]细胞不表达细胞溶解酶,一种与肿瘤入侵相关的金属蛋白酶。有报道称,SW480 [SW-480]细胞表达GM-CSF。SW480 [SW-480]细胞ras原癌基因的12位密码子有一个突变,可以用作PCR法检测该突变的阳性对照。1978年11月,A·Leibovitz将其提交给ATCC时已传代至第91代。 |
年龄(性别) | 男性;50岁 |
组织来源 | 直肠;结直肠腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肠癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~30-50 hours |
致瘤性 | Yes. Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells. |
受体表达情况 | epidermal growth factor (EGF) |
基因表达情况 | carcinoembryonic antigen (CEA) 0.7 ng/10^6 cells/10 days; keratin; transforming growth factor beta, myc+; myb+ ; ras+; fos+; sis+; p53+; abl -; ros -; src -, HLA A2, B8, B17; Blood Type A; Rh+, The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb, sis and fos oncogenes. |
保藏机构 | ATCC; CCL-228 DSMZ; ACC-313 ECACC; 87092801 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 13,14 D2S1338 17,24 D3S1358 15 D5S818 13 D7S820 8 D8S1179 13 D13S317 12 D16S539 13 D18S51 13 D19S433 13 D21S11 30,30.2 FGA 24 PentaD 9,15 PentaE 10 TH01 8 TPOX 11 vWA 16 D6S1043 11,12 D12S391 17 D2S441 10,15 -
STR鉴定图
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参考文献
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Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity (2025-01-16)
期刊:Cell Reports Medicine
DOI:10.1016/j.xcrm.2024.101913
影响因子 :11.7
引用产品: B16-F10 细胞 , 293T [HEK-293T] 细胞 , CT26.WT 细胞 , SW480 [SW-480] 细胞 , THP-1 细胞 , HCT 116 细胞 , TE-1 细胞
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Visualization of carboxylesterase 2 regulation in kidney injury via an enzyme-activated fluorescent probe (2025-01-22)
期刊:SENSORS AND ACTUATORS B-CHEMICAL
影响因子 :8.0
引用产品: SW480 [SW-480] 细胞 , MCF7 [MCF-7] 细胞 , A-375 细胞 , HL-7702 [L-02; LO2] 细胞 , Hep G2 细胞
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TYMS Enhances Colorectal Cell Antioxidant Capacity Via the KEAP1-NRF2 Pathway to Resist Ferroptosis (2025-01-01)
期刊:Journal of Cancer
影响因子 :3.3
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , HT-29 细胞 , HCT-8 [HRT-18] 细胞 , HCT 116 细胞 , LoVo 细胞
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TRIM36 Inhibits the Development of AOM/DSS-Induced Colitis-Associated Colorectal Cancer by Promoting the Ubiquitination and Degradation of GRB7 (2025-01-13)
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23871
影响因子 :3.0
引用产品: COLO 205 细胞 , HCT 116 细胞 , T84 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞
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D3S-001, a KRAS G12C inhibitor with rapid target engagement kinetics, overcomes nucleotide cycling and demonstrates robust preclinical and clinical activities (2024-05-08)
期刊:Cancer Discovery
DOI:10.1158/2159-8290.CD-24-0006
影响因子 :28.2
引用产品: AGS 细胞 , A549 [A-549] 细胞 , A-375 细胞 , KYSE-410 细胞 , NCI-H358 细胞 , AsPC-1 细胞 , BxPC-3 细胞 , HCT-15 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞
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Mitochondrial genome transfer drives metabolic reprogramming in adjacent colonic epithelial cells promoting TGFβ1-mediated tumor progression (2024-04-30)
期刊:Nature Communications
DOI:10.1038/s41467-024-48100-y
影响因子 :16.6
引用产品: SW480 [SW-480] 细胞 , 293T [HEK-293T] 细胞 , HCT 116 细胞 , HT-29 细胞 , SW620 细胞 , RKO 细胞
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Dual activation of GCGR/GLP1R signaling ameliorates intestinal fibrosis via metabolic regulation of histone H3K9 lactylation in epithelial cells (2024-11-26)
期刊:Acta Pharmaceutica Sinica B
DOI:10.1016/j.apsb.2024.11.017
影响因子 :14.7
引用产品: IEC-6 细胞 , SW480 [SW-480] 细胞
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Enhancing tumor-specific recognition of programmable synthetic bacterial consortium for precision therapy of colorectal cancer (2024-01-20)
期刊:npj Biofilms and Microbiomes
DOI:10.1038/s41522-024-00479-8
影响因子 :9.2
引用产品: CT26.WT 细胞 , RKO 细胞 , SW480 [SW-480] 细胞
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PRDX1 inhibits ferroptosis by binding to Cullin-3 as a molecular chaperone in colorectal cancer (2024-09-23)
期刊:International Journal of Biological Sciences
影响因子 :8.2
引用产品: HCT 116 细胞 , SW620 细胞 , SW480 [SW-480] 细胞
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Circular RNA circWBSCR22 facilitates colorectal cancer metastasis by enhancing CHD4's protein stability (2024-10-30)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2024.137135
影响因子 :7.7
引用产品: SW480 [SW-480] 细胞 , 293T [HEK-293T] 细胞 , HCT 116 细胞
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Hsa_circ_0007718 facilitates the progression of colorectal cancer by regulating the miR-1299/PSMC2 axis (2024-10-11)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2024.136537
影响因子 :7.7
引用产品: HT-29 细胞 , SW620 细胞 , NCM460 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞
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A probiotic Limosilactobacillus fermentum GR-3 mitigates colitis-associated tumorigenesis in mice via modulating gut microbiome (2024-09-06)
期刊:npj Science of Food
DOI:10.1038/s41538-024-00307-5
影响因子 :6.3
引用产品: SW480 [SW-480] 细胞 , RKO 细胞
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SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway (2024-03-08)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2024.111759
影响因子 :5.6
引用产品: DLD-1 细胞 , SW480 [SW-480] 细胞 , NCM460 细胞
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Forming Single-Cell-Derived Colon Cancer Organoid Arrays on a Microfluidic Chip for High Throughput Tumor Heterogeneity Analysis (2024-08-01)
期刊:ACS Biomaterials Science & Engineering
DOI:10.1021/acsbiomaterials.4c00727
影响因子 :5.4
引用产品: SW480 [SW-480] 细胞 , HCT 116 细胞 , HT-29 细胞
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RUNX1-induced upregulation of PTGS2 enhances cell growth, migration and invasion in colorectal cancer cells (2024-05-22)
期刊:Scientific Reports
DOI:10.1038/s41598-024-60296-z
影响因子 :4.6
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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Can thymosin beta 10 function both as a non-invasive biomarker and chemotherapeutic target in human colorectal cancer? (2024-06-07)
期刊:Translational Oncology
DOI:10.1016/j.tranon.2024.102026
影响因子 :4.5
引用产品: SW480 [SW-480] 细胞 , HT-29 细胞
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Network-based prediction of anti-cancer drug combinations (2024-08-15)
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2024.1418902
影响因子 :4.4
引用产品: SW480 [SW-480] 细胞 , HCT 116 细胞 , BxPC-3 细胞
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Identification and validation of basement membrane-associated gene AGRN as prognostic and immune-associated biomarkers in colorectal cancer patients (2024-08-25)
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 :4.3
引用产品: SW480 [SW-480] 细胞
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Entero-toxigenic Bacteroides fragilis contributes to intestinal barrier injury and colorectal cancer progression by mediating the BFT/STAT3/ZEB2 pathway (2024-01-25)
期刊:CELL CYCLE
DOI:10.1080/15384101.2024.2309005
影响因子 :4.3
引用产品: SW480 [SW-480] 细胞 , Caco-2 细胞
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NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis (2024-06-24)
期刊:Aging-US
影响因子 :3.9
引用产品: LoVo 细胞 , DLD-1 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞
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Multi-omics analysis of the biological function of the VEGF family in colon adenocarcinoma (2024-11-11)
期刊:FUNCTIONAL & INTEGRATIVE GENOMICS
DOI:10.1007/s10142-024-01493-x
影响因子 :3.9
引用产品: SW480 [SW-480] 细胞
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PTPN11 is a potential biomarker for type 2 diabetes mellitus complicated with colorectal cancer (2024-10-24)
期刊:Scientific Reports
DOI:10.1038/s41598-024-75889-x
影响因子 :3.8
引用产品: SW480 [SW-480] 细胞
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Intestinal metabolite xylulose inhibits colorectal cancer by inducing apoptosis through the MAPK signalling pathway (2024-05-10)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2024.116960
影响因子 :3.8
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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Zinc finger protein 263 promotes colorectal cancer cell progression by activating STAT3 and enhancing chemoradiotherapy resistance (2024-09-18)
期刊:Scientific Reports
DOI:10.1038/s41598-024-72636-0
影响因子 :3.8
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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NSUN6 mediates 5-methylcytosine modification of METTL3 and promotes colon adenocarcinoma progression (2024-05-27)
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.6
引用产品: HCT-8 [HRT-18] 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞
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TL1A promotes metastasis and EMT process of colorectal cancer (2024-01-15)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e24392
影响因子 :3.4
引用产品: SW480 [SW-480] 细胞 , LoVo 细胞 , SW620 细胞 , RKO 细胞 , HCT 116 细胞 , HCT116 细胞(荧光素酶标记) , FHC 细胞
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DDX18 influences chemotherapy sensitivity in colorectal cancer by regulating genomic stability (2024-11-20)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2024.114344
影响因子 :3.3
引用产品: SW620 细胞 , SW480 [SW-480] 细胞 , RKO 细胞 , HCT 116 细胞 , HT-29 细胞
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Thiostrepton suppresses colorectal cancer progression through reactive oxygen species related endoplasmic reticulum stress (2024-12-27)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2024.117221
影响因子 :3.3
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , McCoy's 5A 培养基 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液(双抗),100× , Annexin V-APC/PI荧光双染细胞凋亡检测试剂盒
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MiR-214-3p overexpression-triggered chondroitin polymerizing factor (CHPF) inhibition modulates the ferroptosis and metabolism in colon cancer (2024-01-08)
期刊:KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 :3.3
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , LoVo 细胞 , DMEM高糖 培养基 , 青霉素-链霉素溶液 (双抗),100× , Ham's F-12K 培养基
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Development of a Novel Prognostic Panel for Colorectal Cancer Based on Cancer Functional Status, and Validation of STC2 as a Promising Biomarker (2024-07-02)
期刊:Frontiers in Bioscience-Landmark
影响因子 :3.3
引用产品: SW480 [SW-480] 细胞 , HCT 116 细胞 , LoVo 细胞 , NCM460 细胞
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Circ_0006174 Upregulates IGF1R to Enhance Radioresistance and Tumorigenesis in Colorectal Cancer via miR-940 Suppression (2024-08-22)
期刊:APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI:10.1007/s12010-024-05028-9
影响因子 :3.1
引用产品: SW480 [SW-480] 细胞 , SW620 细胞
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Jianpi Jiedu Recipe Inhibits Proliferation through Reactive Oxygen Species-Induced Incomplete Autophagy and Reduces PD-L1 Expression in Colon Cancer (2024-08-18)
期刊:INTEGRATIVE CANCER THERAPIES
影响因子 :2.9
引用产品: HT-29 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞
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The role of HM13 expression and its relationship to PI3K/Akt and p53 signaling pathways in colorectal cancer (2024-12-27)
期刊:TISSUE & CELL
DOI:10.1016/j.tice.2024.102702
影响因子 :2.7
引用产品: NCM460 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , LoVo 细胞 , HT-29 细胞
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Matrine promotes colorectal cancer apoptosis by downregulating shank-associated RH domain interactor expression (2024-12-15)
期刊:World Journal of Gastrointestinal Oncology
影响因子 :2.5
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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Piperine induces autophagy of colon cancer cells: Dual modulation of AKT/mTOR signaling pathway and ROS production (2024-07-02)
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2024.150340
影响因子 :2.5
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , DLD-1 细胞 , CT26.WT 细胞 , NCM460 细胞 , IEC-6 细胞
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E3 Ubiquitination Ligase MYLIP Mediates the NKRF/SLC25A34 Axis to Suppress Malignant Progression in Colorectal Cancer (2024-12-11)
期刊:DIGESTIVE DISEASES AND SCIENCES
DOI:10.1007/s10620-024-08735-9
影响因子 :2.5
引用产品: HCT-15 细胞 , HCT 116 细胞 , HT-29 细胞 , SW480 [SW-480] 细胞
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The Combination of SHP099 Inhibits the Malignant Biological Behavior of L-OHP/5-FU-Resistant Colorectal Cancer Cells by Regulating Energy Metabolism Reprogramming (2024-06-28)
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2024.150262
影响因子 :2.5
引用产品: HT-29 细胞 , SW480 [SW-480] 细胞
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In-depth study of pyroptosis-related genes and immune infiltration in colon cancer (2024-10-29)
期刊:PeerJ
影响因子 :2.3
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , HT-29 细胞 , SW620 细胞
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Forkhead box D subfamily genes in colorectal cancer: potential biomarkers and therapeutic targets (2024-10-29)
期刊:PeerJ
影响因子 :2.3
引用产品: HT-29 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , SW620 细胞
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Circ_0089761 accelerates colorectal cancer metastasis and immune escape via miR-27b-3p/PD-L1 axis (2024-12-04)
期刊:Physiological Reports
影响因子 :2.2
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , 特级胎牛血清
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Activation of the WNT7B/β-Catenin Pathway Initiates GLUT1 Expression and Promotes Aerobic Glycolysis in Colorectal Cancer Cells (2024-10-21)
期刊:NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
DOI:10.1080/01635581.2024.2418607
影响因子 :2.0
引用产品: SW480 [SW-480] 细胞
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WTAP-mediated m6A modification regulates NLRP3/Caspase-1/GSDMD to inhibit pyroptosis and exacerbate colorectal cancer (2024-10-29)
期刊:Biomarkers in Medicine
DOI:10.1080/17520363.2024.2416886
影响因子 :1.9
引用产品: DLD-1 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞
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Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers (2023-03-10)
期刊:JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1021/acs.jmedchem.3c00075
影响因子 :7.3
引用产品: Calu-1 细胞 , SW480 [SW-480] 细胞 , CAL-62 细胞 , LoVo 细胞 , HCT 116 细胞 , NCI-H460 [H460] 细胞
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Design, synthesis, and biological evaluation of 1,6-naphthyridine-2-one derivatives as novel FGFR4 inhibitors for the treatment of colorectal cancer (2023-08-04)
期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1016/j.ejmech.2023.115703
影响因子 :6.7
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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Pan-cancer analysis of PLAU indicates its potential prognostic value and correlation with neutrophil infiltration in BLCA (2023-11-22)
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI:10.1016/j.bbadis.2023.166965
影响因子 :6.2
引用产品: MCF7 [MCF-7] 细胞 , Caco-2 细胞 , SW480 [SW-480] 细胞 , CAL 27 细胞 , KHM-5M 细胞 , SV-HUC-1 细胞 , 5637 细胞 , UM-UC-3 细胞 , EJ-1 细胞 , T24 [T-24] 细胞 , TCCSUP 细胞
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Identification and validation of a novel prognosis model based on m5C-related long non-coding RNAs in colorectal cancer (2023-09-05)
期刊:Cancer Cell International
DOI:10.1186/s12935-023-03025-2
影响因子 :5.8
引用产品: NCM460 细胞 , SW620 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , DLD-1 细胞 , LoVo 细胞 , HT-29 细胞
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The Males Absent on the First (MOF) Mediated Acetylation Alters the Protein Stability and Transcriptional Activity of YY1 in HCT116 Cells (2023-05-13)
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.6
引用产品: SW480 [SW-480] 细胞 , 特级胎牛血清
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The combination of phosphoinositol with inositol suppresses colorectal cancer growth and metastasis by regulating CLDN23/ RhoA /ROCK1 pathway (2023-11-08)
期刊:Journal of Functional Foods
影响因子 :5.6
引用产品: SW620 细胞 , SW480 [SW-480] 细胞
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Loss of Tumor Suppressor C9orf9 Promotes Metastasis in Colorectal Cancer (2023-02-07)
期刊:Biomolecules
影响因子 :5.5
引用产品: SW480 [SW-480] 细胞 , LoVo 细胞
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Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells (2023-03-12)
期刊:FEBS Journal
影响因子 :5.4
引用产品: HT-29 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , NCM460 细胞
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Identification of differentially expressed HERV-K(HML-2) loci in colorectal cancer (2023-06-05)
期刊:Frontiers in Microbiology
DOI:10.3389/fmicb.2023.1192900
影响因子 :5.2
引用产品: HT-29 细胞 , SW480 [SW-480] 细胞
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KIF18A improves migration and invasion of colorectal cancer (CRC) cells through inhibiting PTEN signaling (2023-09-13)
期刊:Aging-US
影响因子 :5.2
引用产品: SW480 [SW-480] 细胞 , HT-29 细胞
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m6A methyltransferase METTL16 mediates immune evasion of colorectal cancer cells via epigenetically regulating PD-L1 expression (2023-08-29)
期刊:Aging-US
影响因子 :5.2
引用产品: 人结肠黏膜上皮细胞 , RKO 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , COLO 320DM 细胞
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Characterization of SHCBP1 to prognosis and immunological landscape in pan-cancer: novel insights to biomarker and therapeutic targets (2023-03-14)
期刊:Aging-US
影响因子 :5.2
引用产品: SW480 [SW-480] 细胞 , HCT 116 细胞 , NCM460 细胞
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Exosomal circCOL1A2 from cancer cells accelerates colorectal cancer progression via regulating miR-665/LASP1 signal axis (2023-04-12)
期刊:EUROPEAN JOURNAL OF PHARMACOLOGY
DOI:10.1016/j.ejphar.2023.175722
影响因子 :5.0
引用产品: HT-29 细胞 , HCT 116 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , 人结肠黏膜上皮细胞
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The role of KNTC1 in the regulation of proliferation, migration and tumorigenesis in colorectal cancer (2023-05-23)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2023.110728
影响因子 :4.8
引用产品: HCT 116 细胞 , RKO 细胞 , SW480 [SW-480] 细胞
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Inorganic pyrophosphatase 1 activates the phosphatidylinositol 3-kinase/Akt signaling to promote tumorigenicity and stemness properties in colorectal cancer (2023-05-02)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2023.110693
影响因子 :4.8
引用产品: 特级胎牛血清 , HCT 116 细胞 , SW480 [SW-480] 细胞 , Caco-2 细胞 , LoVo 细胞 , HCT 116细胞专用培养基 , SW480 [SW-480]细胞专用培养基 (L15) , Caco-2细胞专用培养基 , LoVo细胞专用培养基
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Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway (2023-12-27)
期刊:Pharmaceuticals
影响因子 :4.6
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , CT26.WT 细胞
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Anti-Colorectal Cancer Activity of Solasonin from Solanum nigrum L. via Histone Deacetylases-Mediated p53 Acetylation Pathway (2023-09-15)
期刊:MOLECULES
影响因子 :4.6
引用产品: SW620 细胞 , SW480 [SW-480] 细胞 , A549 [A-549] 细胞 , MGC80-3 [MGC-803] 细胞
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The Upregulation of GSTO2 is Associated with Colon Cancer Progression and a Poor Prognosis (2023-01-11)
期刊:Journal of Oncology
影响因子 :4.5
引用产品: HT-29 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞
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Matrine restrains the development of colorectal cancer through regulating the AGRN/Wnt/β-catenin pathway (2023-01-09)
期刊:ENVIRONMENTAL TOXICOLOGY
影响因子 :4.5
引用产品: NCM460 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞
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Annexin A9 promotes cell proliferation by regulating the Wnt signaling pathway in colorectal cancer (2023-06-22)
期刊:Human Cell
DOI:10.1007/s13577-023-00939-x
影响因子 :4.3
引用产品: LoVo 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , HT-29 细胞 , 人结肠黏膜上皮细胞
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CILP2: A prognostic biomarker associated with immune infiltration in colorectal cancer (2023-04-20)
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e15535
影响因子 :4.0
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , RKO 细胞 , 人结肠黏膜上皮细胞
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P300 increases CSNK2A1 expression which accelerates colorectal cancer progression through activation of the PI3K-AKT-mTOR axis (2023-06-28)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2023.113694
影响因子 :3.7
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , LoVo 细胞 , HT-29 细胞
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Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway (2023-06-22)
期刊:PLoS One
DOI:10.1371/journal.pone.0287133
影响因子 :3.7
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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ELAPOR1 suppresses tumor progression in colorectal cancer and indicates favorable prognosis (2023-06-03)
期刊:Cancer Biomarkers
影响因子 :3.1
引用产品: SW620 细胞 , RKO 细胞 , SW480 [SW-480] 细胞 , HT-29 细胞 , Caco-2 细胞 , HCT 116 细胞 , 293T [HEK-293T] 细胞
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Naringin Inhibits Colorectal Carcinogenesis by Inhibiting Viability of Colorectal Cancer Cells (2023-06-21)
期刊:Chinese Journal of Integrative Medicine
影响因子 :2.9
引用产品: Caco-2 细胞 , HCT 116 细胞 , HT-29 细胞 , SW480 [SW-480] 细胞 , MEM 培养基 , McCoy's 5A 培养基 , Leibovitz's L-15 培养基
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RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer (2023-07-27)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.8
引用产品: DLD-1 细胞 , HT-29 细胞 , SW480 [SW-480] 细胞
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Circ_0087862 promotes tumorigenesis and glycolysis in colorectal cancer by sponging miR-296-3p to regulate PGK1 expression (2023-07-17)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.8
引用产品: LoVo 细胞 , SW620 细胞 , HT-29 细胞 , SW480 [SW-480] 细胞
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Development and validation of cuproptosis-related lncRNA signatures for prognosis prediction in colorectal cancer (2023-03-22)
期刊:BMC Medical Genomics
DOI:10.1186/s12920-023-01487-x
影响因子 :2.7
引用产品: FHC 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , HCT-8 [HRT-18] 细胞 , HT-29 细胞 , LoVo 细胞
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Circular RNA (circ)_0053277 Contributes to Colorectal Cancer Cell Growth, Angiogenesis, Metastasis and Glycolysis (2023-11-02)
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-023-00936-3
影响因子 :2.6
引用产品: NCI-H460 [H460] 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , 人脐静脉内皮细胞
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Circ_0000370 Plays an Oncogenic Role in Colorectal Cancer by Regulating the miR-502-5p/SIRT1 Axis (2023-08-10)
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-023-10468-9
影响因子 :2.4
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , 人结肠黏膜上皮细胞
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Circ_0005615 Regulates the Progression of Colorectal Cancer Through the miR-873-5p/FOSL2 Signaling Pathway (2023-03-15)
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-023-10355-3
影响因子 :2.4
引用产品: HCT 116 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞 , 人结肠黏膜上皮细胞 , RPMI-1640 培养基 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , 磷酸盐缓冲液 (PBS) 1×
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TRIM29 knockdown prevented the colon cancer progression through decreasing the ubiquitination levels of KRT5 (2023-08-30)
期刊:Open Life Sciences
影响因子 :2.2
引用产品: 人结肠黏膜上皮细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , SW620 细胞 , LoVo 细胞 , RKO 细胞
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Hsa_Circ_0104206 is An Oncogenic circRNA in Colon Cancer by Targeting Mir-188–3p/CCNA2 Axis (2023-06-05)
期刊:HORMONE AND METABOLIC RESEARCH
影响因子 :2.2
引用产品: HCT-8 [HRT-18] 细胞 , SW620 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , 特级胎牛血清
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NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer (2023-02-27)
期刊:Journal of Gastrointestinal Oncology
影响因子 :2.1
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , HT-29 细胞
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The combination of inositol hexaphosphate and inositol inhibits metastasis of colorectal cancer cells by upregulating claudin 7 (2023-06-08)
期刊:BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子 :2.0
引用产品: SW480 [SW-480] 细胞 , SW620 细胞
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Cryptotanshinone, a Potential SIRT3 Inhibitor, Suppresses Colorectal Cancer Proliferation in vitro and in vivo (2023-08-18)
期刊:Natural Product Communications
影响因子 :1.8
引用产品: SW480 [SW-480] 细胞 , SW620 细胞
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Exosomes-derived miR-548am-5p promotes colorectal cancer progression (2023-11-30)
期刊:CELLULAR AND MOLECULAR BIOLOGY
DOI:10.14715/cmb/2023.69.12.17
影响因子 :1.6
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , RKO 细胞 , LoVo 细胞
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Vitamin D Inhibits Colorectal Cancer Cell Proliferation, Migration and Invasion via Downregulating the Notch1 Pathway (2023-07-31)
期刊:CELLULAR AND MOLECULAR BIOLOGY
影响因子 :1.6
引用产品: SW480 [SW-480] 细胞 , 青霉素-链霉素溶液 (双抗),100×
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Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer (2022-08-28)
期刊:Advanced Science
影响因子 :17.5
引用产品: SW480 [SW-480] 细胞 , HT-29 细胞 , SW620 细胞
-
Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA (2022-12-15)
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-022-02551-7
影响因子 :12.7
引用产品: 293T [HEK-293T] 细胞 , NCM460 细胞 , SW480 [SW-480] 细胞 , DLD-1 细胞 , HT-29 细胞 , RKO 细胞 , HCT 116 细胞
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Design, synthesis and evaluation of N3-substituted quinazolinone derivatives as potential Bloom's Syndrome protein (BLM) helicase inhibitor for sensitization treatment of colorectal cancer (2022-11-21)
期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1016/j.ejmech.2022.114944
影响因子 :7.1
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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LncRNA-ENST00000543604 exerts a tumor-promoting effect via miRNA 564/AEG-1 or ZNF326/EMT and predicts the prognosis of and chemotherapeutic effect in colorectal cancer. (2022-08-23)
期刊:Frontiers in Oncology
影响因子 :5.7
引用产品: RKO 细胞 , HT-29 细胞 , FHC 细胞 , HCT 116 细胞 , HCT-15 细胞 , SW620 细胞 , SW480 [SW-480] 细胞
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Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer (2022-01-26)
期刊:Biomedical Journal
影响因子 :5.5
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , LoVo 细胞 , HCT 116 细胞 , RPMI-1640 培养基 , DMEM高糖 培养基 , 特级胎牛血清
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Oct4 promoted proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) in colon cancer cells by activating the SCF/c-Kit signaling pathway (2022-10-18)
期刊:CELL CYCLE
DOI:10.1080/15384101.2022.2112486
影响因子 :5.2
引用产品: HT-29 细胞 , SW480 [SW-480] 细胞
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Hsa_circ_0003602 Contributes to the Progression of Colorectal Cancer by Mediating the miR-149-5p/SLC38A1 Axis (2022-09-23)
期刊:Gut and Liver
影响因子 :4.3
引用产品: SW620 细胞 , HCT 116 细胞 , DMEM高糖 培养基 , 青霉素-链霉素溶液(双抗),100× , SW480 [SW-480] 细胞 , 特级胎牛血清 , LoVo 细胞
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Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer (2022-08-02)
期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI:10.1007/s11010-022-04525-x
影响因子 :3.8
引用产品: LoVo 细胞 , SW620 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , 特级胎牛血清 , Leibovitz's L-15 培养基 , McCoy's 5A 培养基
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HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability (2022-09-01)
期刊:NEOPLASMA
DOI:10.4149/neo_2022_220331N363
影响因子 :3.4
引用产品: DLD-1 细胞 , SW480 [SW-480] 细胞
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CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway (2022-08-15)
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2022.08.036
影响因子 :3.3
引用产品: LS180 细胞 , SW480 [SW-480] 细胞 , HT-29 细胞 , HCT 116 细胞 , DLD-1 细胞
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Design, Synthesis and Biological Evaluation of Novel 1, 3, 4-Oxadiazole PD176252 Analogues as Potential GRPR Inhibitors (2022-10-01)
期刊:Anti-Cancer Agents in Medicinal Chemistry
DOI:10.2174/1871520622666220501162813
影响因子 :2.5
引用产品: PC-3 细胞 , HGC-27 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , A549 [A-549] 细胞 , HK-2 细胞
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Identification and characterization of the inhibitory effect of ART on colorectal cancer cells using Raman spectroscopy (2022-01-10)
期刊:Journal of Raman Spectroscopy
DOI:10.1002/jrs.6292
影响因子 :2.5
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , HCT 116 细胞 , Leibovitz's L-15 培养基 , McCoy's 5A 培养基
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ISLR affects colon cancer progression by regulating the epithelial–mesenchymal transition signaling pathway (2022-01-01)
期刊:Anti-Cancer Drugs
DOI:10.1097/CAD.0000000000001233
影响因子 :2.3
引用产品: 人结肠黏膜上皮细胞 , CX-1 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , HT-29 细胞 , Hs 578T 细胞
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Galloflavin Relieves the Malignant Behavior of Colorectal Cancer Cells in the Inflammatory Tumor Microenvironment. (2021-12-10)
期刊:Frontiers in Pharmacology
影响因子 :5.6
引用产品: SW480 [SW-480] 细胞
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Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal cancer organoids (2021-08-15)
期刊:Cancer Biology & Medicine
DOI:10.20892/j.issn.2095-3941.2020.0566
影响因子 :5.5
引用产品: SW620 细胞 , SW480 [SW-480] 细胞 , DLD-1 细胞 , COLO 205 细胞
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Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis (2021-10-21)
期刊:Journal Of Physiology And Biochemistry
DOI:10.1007/s13105-021-00832-x
影响因子 :5.1
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , HCT 116 细胞 , COLO 205 细胞 , LoVo 细胞
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MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2 (2021-10-16)
期刊:Bioengineered
DOI:10.1080/21655979.2021.1996505
影响因子 :4.9
引用产品: HT-29 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞 , HCT 116 细胞 , PUMC-HUVEC-T1
-
MicroRNA?129 inhibits colorectal cancer cell proliferation, invasion and epithelial?to?mesenchymal transition by targeting SOX4 (2021-03-24)
期刊:Oncology Reports
影响因子 :4.2
引用产品: SW620 细胞 , SW480 [SW-480] 细胞
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Deoxycholic acid-modified microporous SiO2 nanofibers mimicking colorectal microenvironment to optimize radiotherapy-chemotherapy combined therapy (2021-10-12)
期刊:Biomedical Materials
影响因子 :4.1
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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Photodynamic effect of chlorin e6 on cytoskeleton protein of human colon cancer SW480 cells (2021-01-30)
期刊:Photodiagnosis and Photodynamic Therapy
DOI:10.1016/j.pdpdt.2021.102201
影响因子 :3.3
引用产品: SW480 [SW-480] 细胞
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Circ_0029803 serves as the sponge of miR-216b-5p to promote the progression of colorectal cancer by regulating SKIL expression (2021-09-03)
期刊:World Journal of Surgical Oncology
DOI:10.1186/s12957-021-02368-2
影响因子 :3.2
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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NDRG4 sensitizes CRC cells to 5-FU by upregulating DDIT3 expression (2021-09-13)
期刊:Oncology Letters
影响因子 :2.9
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , 293T [HEK-293T] 细胞
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microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16 (2021-08-26)
期刊:In Vitro Cellular & Developmental Biology-Animal
DOI:10.1007/s11626-021-00603-4
影响因子 :2.7
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , HCT 116 细胞 , LoVo 细胞 , Caco-2 细胞 , Leibovitz's L-15 培养基 , Ham's F-12K 培养基 , McCoy's 5A 培养基
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circASS1 overexpression inhibits the proliferation, invasion and migration of colorectal cancer cells by regulating the miR?1269a/VASH1 axis (2021-08-10)
期刊:Experimental and Therapeutic Medicine
影响因子 :2.7
引用产品: HCT 116 细胞 , Caco-2 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞 , HT-29 细胞
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CHIP-mediated ubiquitination of Galectin-1 predicts colorectal cancer prognosis (2020-01-14)
期刊:International Journal of Biological Sciences
影响因子 :9.2
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞
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Amphoteric natural starch-coated polymer nanoparticles with excellent protein corona-free and targeting properties (2020-01-28)
期刊:Nanoscale
影响因子 :6.9
引用产品: SW480 [SW-480] 细胞 , A549 [A-549] 细胞
-
Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer (2020-01-03)
期刊:Aging-US
影响因子 :5.2
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , RKO 细胞 , CT26.WT 细胞
-
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis (2020-04-30)
期刊:Bioengineered
DOI:10.1080/21655979.2020.1757224
影响因子 :4.9
引用产品: SW620 细胞 , SW480 [SW-480] 细胞 , Caco-2 细胞 , LoVo 细胞 , 293T [HEK-293T] 细胞 , Ham's F-12K 培养基
-
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer (2020-06-28)
期刊:Cell Cycle
DOI:10.1080/15384101.2020.1783058
影响因子 :4.3
引用产品: SW480 [SW-480] 细胞 , LoVo 细胞 , Ham's F-12K 培养基
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The bromodomain and extra-terminal domain inhibitor JQ1 synergistically sensitizes human colorectal cancer cells to topoisomerase I inhibitors through repression of Mre11-mediated DNA repair pathway (2020-09-26)
期刊:Investigational New Drugs
DOI:10.1007/s10637-020-01014-0
影响因子 :3.4
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞 , HT-29 细胞 , LoVo 细胞 , RKO 细胞
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Anti-cancer effects of Porphyra haitanensis polysaccharides on human colon cancer cells via cell cycle arrest and apoptosis without causing adverse effects in vitro (2020-08-11)
期刊:3 BIOTECH
DOI:10.1007/s13205-020-02379-y
影响因子 :2.8
引用产品: HT-29 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞
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Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer (2019-06-10)
期刊:Cancer Letters
DOI:10.1016/j.canlet.2019.04.014
影响因子 :9.7
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , HCT 116 细胞 , HT-29 细胞 , RKO 细胞 , LoVo 细胞
-
A 3-circular RNA signature as a noninvasive biomarker for diagnosis of colorectal cancer (2019-11-04)
期刊:Cancer Cell International
影响因子 :5.8
引用产品: HCT 116 细胞 , SW480 [SW-480] 细胞 , SW620 细胞
-
miR-145-5p restrained cell growth, invasion, migration and tumorigenesis via modulating RHBDD1 in colorectal cancer via the EGFR-associated signaling pathway (2019-11-03)
期刊:International Journal Of Biochemistry & Cell Biology
DOI:10.1016/j.biocel.2019.105641
影响因子 :4.0
引用产品: Caco-2 细胞 , DLD-1 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞 , T84 细胞
-
SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway (2019-06-30)
期刊:Clinical And Experimental Pharmacology And Physiology
影响因子 :2.9
引用产品: SW480 [SW-480] 细胞 , SW620 细胞 , HCT 116 细胞 , COLO 205 细胞 , LoVo 细胞
-
Mitochondrial DNA content reduction induces aerobic glycolysis and reversible resistance to drug-induced apoptosis in SW480 colorectal cancer cells (2018-04-24)
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2018.04.099
影响因子 :7.5
引用产品: SW480 [SW-480] 细胞
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