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产品概述
名称 | Calu-1 (人肺癌细胞) (STR鉴定正确) |
别称 | CaLu-1; CALU-1; CALU 1; Calu 1; CALU1; Calu1 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | Calu-1细胞超微结构特征包括众多微绒毛、显著的粗面内质网、溶酶体、脂包含体、无病毒颗粒;此外,Calu-1细胞含ras(H-ras)癌基因。 |
年龄(性别) | 男性;47岁 |
组织来源 | 器官:肺;肿瘤分期:Ⅲ期;疾病:表皮瘤;取材转移灶:肋膜 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~37 hours |
致瘤性 | Yes, in nude mice; forms epidermoid carcinomas.Yes, in steroid treated hamsters. |
基因表达情况 | Blood Type A; Rh+; HLA A10, A11, B15, Bw35 |
保藏机构 | ATCC; HTB-54 ECACC; 93120818 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10 D2S1338 16,17 D3S1358 17 D5S818 10,12 D7S820 9,10 D8S1179 10 D13S317 11,12 D16S539 11 D18S51 14,17 D19S433 13,15 D21S11 28 FGA 20,21 PentaD 9 PentaE 11 TH01 9,9.3 TPOX 8 vWA 15,16 D6S1043 17,19 D12S391 18,20 D2S441 10,11 -
STR鉴定图
参考文献
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Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis (2024-02-23)
作者:Qiuyan Guo:1.State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. ; Minghong Zhao:1.First Affiliated Hospital of Gannan Medical University, No. 23, Qingnian Road, Ganzhou, Jiangxi 341000, China. ; Qixin Wang:1.State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. ; Tianming Lu:1.State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. ; Piao Luo:1.State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academ
期刊:Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis
DOI:10.1016/j.biopha.2024.116304
影响因子 :7.5
引用产品: A549 [A-549] 细胞 , Calu-1 细胞
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Design, synthesis and biological evaluation of rhein–piperazine–furanone hybrids as potential anticancer agents (2024-02-13)
作者:Yu He:1.State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, Ningxia Research Center for Natural Medicine Engineering and Technology, College of Chemistry and Chemical Engineering, Ningxia University 489 Helanshan West Road Yinchuan 750021 China weimengxue@nxu.edu.cn. ; Si-Si Zhang:1.State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, Ningxia Research Center for Natural Medicine Engineering and Technology, College of Chemistry and Chemical Engineering, Ningxia University 489 Helanshan West Road Yinchuan 750021 China weimengxue@nxu.edu.cn. ; Meng-Xue Wei:1.State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, Ningxia Research Center for Natural Medicine Engineering and Technology, College of Chemistry and Chemical Engineering, Ningxia University 489 Helanshan West Road Yinchuan 750021 China weimengxue@nxu.edu.cn. ;
期刊:Design, synthesis and biological evaluation of rhein–piperazine–furanone hybrids as potential anticancer agents
影响因子 :4.1
引用产品: A549 [A-549] 细胞 , NCI-H460 [H460] 细胞 , PC-9 细胞 , Calu-1 细胞 , SK-BR-3 [SKBR3] 细胞 , SK-OV-3 细胞 , 786-O [786-0] 细胞 , HuH-7 细胞 , HCT 116 细胞 , Hela 细胞 , WI-38 细胞 , MCF 10A 细胞 , KGN 细胞 , 293T [HEK-293T] 细胞 , DMEM高糖 培养基 , MEM 培养基 , DMEM/F12 培养基 , McCoy's 5A 培养基 , RPMI-1640 培养基 , 0.25%胰蛋白酶溶液 (含EDTA,溶于PBS)
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PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway (2024-01-19)
作者:Junqi Lv:1.Department of Thoracic Surgery, People's Hospital of Ningxia Hui Autonomous Region, No. 301, Zhengyuan North Street, Yinchuan, Ningxia, People's Republic of China. ljqi10358@126.com. ; Shengmao Ma:1.Department of Thoracic Surgery, People's Hospital of Ningxia Hui Autonomous Region, No. 301, Zhengyuan North Street, Yinchuan, Ningxia, People's Republic of China. ; Xiaowen Wang:1.Department of Thoracic Surgery, People's Hospital of Ningxia Hui Autonomous Region, No. 301, Zhengyuan North Street, Yinchuan, Ningxia, People's Republic of China. ; Jifang Dang:1.Department of Thoracic Surgery, People's Hospital of Ningxia Hui Autonomous Region, No. 301, Zhengyuan North Street, Yinchuan, Ningxia, People's Republic of China. ; Fuchun Ma:1.Department of Thoracic Surgery, People's Hospital of Ningxia Hui Autonomous Region, No. 301, Zhengyuan North Street, Yinchuan, Ningxia, People's Republic of China. ;
期刊:PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway
DOI:10.1007/s13258-023-01484-5
影响因子 :2.1
引用产品: BEAS-2B 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , Calu-1 细胞
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Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers (2023-03-10)
作者:Zehui Zhou:1.Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. ; 2.University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China. ; Guizhen Zhou:1.Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. ; 2.School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China. ; Chuan Zhou:1.Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. ; Zisheng Fan:1.Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. ; Rongrong Cui:1.Drug Discovery and Design Center, State Key Laboratory of Drug Rese
期刊:Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
DOI:10.1021/acs.jmedchem.3c00075
影响因子 :7.3
引用产品: Calu-1 细胞 , SW480 [SW-480] 细胞 , CAL-62 细胞 , LoVo 细胞 , HCT 116 细胞 , NCI-H460 [H460] 细胞
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LINC00173.v1 Promotes Angiogenesis and Progression of Lung Squamous Cell Carcinoma by Sponging miR-511-5p to Regulate VEGFA Expression (2007-00-20)
作者:Jiarong Chen:1.Clinical Experimental Center, Jiangmen Key Laboratory of Clinical Biobanks and Translational Research, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, 529030, China. ; 2.Department of Oncology, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, 529030, China. ; Aibin Liu:1.Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, 410008, China. ; 2.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China. ; Zhihui Wang:1.Department of Oncology, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, 529030, China. ; Bin Wang:1.Clinical Experimental Center, Jiangmen Key Laboratory of Clinical Biobanks and Translational Research, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, 529030, China. ; 2.Dongguan Key Labor
期刊:LINC00173.v1 Promotes Angiogenesis and Progression of Lung Squamous Cell Carcinoma by Sponging miR-511-5p to Regulate VEGFA Expression
DOI:10.1186/s12943-020-01217-2
影响因子 :37.3
引用产品: A549 [A-549] 细胞 , Calu-1 细胞 , NCI-H460 [H460] 细胞 , NCI-H292 细胞
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