产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
胰岛素(Insulin,INS)是由胰岛β细胞分泌的一种双链形式(α, β)的多肽激素,不同物种动物(人、牛、羊、猪等)的胰岛素功能大体相同,成分稍有差异,胰岛素是目前已知的机体内唯一降低血糖的激素,也是唯一同时促进糖原、脂肪、蛋白质合成的激素。胰岛素在许多细胞活动中发挥重要作用,是哺乳动物细胞培养基中常用的添加物质胰岛素能加速葡萄糖的利用和抑制葡萄糖的生成,抑制脂肪的分解,促进脂肪的合成和贮存,促进蛋白质的合成,阻止蛋白质的分解,促进钾离子和镁离子穿过细胞膜进入细胞内;促进脱氧核糖核酸(DNA)、核糖核酸(RNA)及三磷酸腺苷(ATP)的合成。
普诺赛生产的重组人胰岛素(Recombinant Human Insulin),分子量约为5800 Da,结构与天然来源的人胰岛素相同,常用作细胞培养的辅助成分,常见使用浓度为1 μg/mL-10 μg/mL。
产品信息
形态 | 液体 |
规格 | 1mL/1mLx5/1mLx10 |
pH | 2.0-3.5 |
重组人胰岛素 | 10 mg/mL |
活性 | ≥275 IU/mL |
储存条件 | -5~-20℃,避光 |
运输条件 | 低温 |
有效期 | 12个月 |
注意事项
1、本产品经0.1 μm过滤除菌,使用本产品时应注意无菌操作,避免污染;
2、本产品为10 mg/mL浓缩液,请根据需要稀释后使用;
3、2-8℃中解冻,混匀后使用,切忌反复冻融,用量较少时建议分装冻存,2-8℃中保存,至少6个月有效;
4、不宜长时间放置于室温或较高温度的环境中;
5、溶解后若有沉淀产生,待溶液升至室温后混匀即可溶解;若遇无法溶解时,用无菌的0.1 M HCl缓慢调节pH至2-3之间(边调节,边用pH试纸检测pH);若仍然无法溶解,请及时与我们联系;
6、本产品仅用于科研或进一步研究使用,不用于诊断和治疗。
参考文献
-
Enhanced antibacterial and antibiofilm activities of quaternized ultra-high deacetylated chitosan against multidrug-resistant bacteria (2025-01-18)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2025.140052
影响因子 :7.7
引用产品: DMEM/F12 培养基 , EGF/Urogastrone/URG, Human, Recombinant , 重组人胰岛素溶液(10 mg/mL)
-
Overexpression of Apolipoprotein A-I Alleviates Insulin Resistance in MASLD Mice Through the PPARα Pathway (2025-01-26)
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :4.9
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
Short-Term Statin Therapy Induces Hepatic Insulin Resistance Through HNF4α/PAQR9/PPM1α Axis Regulated AKT Phosphorylation (2024-07-05)
期刊:Advanced Science
影响因子 :14.3
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
Adipose Tissue-Resident Sphingomonas Paucimobilis Suppresses Adaptive Thermogenesis by Reducing 15-HETE Production and Inhibiting AMPK Pathway (2024-10-30)
期刊:Advanced Science
影响因子 :14.3
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
SLC7A11 protects luminal A breast cancer cells against ferroptosis induced by CDK4/6 inhibitors (2024-08-10)
期刊:Redox Biology
DOI:10.1016/j.redox.2024.103304
影响因子 :10.7
引用产品: 青霉素-链霉素溶液(双抗),100× , 重组人胰岛素溶液(10 mg/mL)
-
Acidosis activates breast cancer ferroptosis through ZFAND5/SLC3A2 signaling axis and elicits M1 macrophage polarization (2024-02-14)
期刊:CANCER LETTERS
DOI:10.1016/j.canlet.2024.216732
影响因子 :9.7
引用产品: McCoy's 5A 培养基 , DMEM高糖 培养基 , 马血清 , EGF/Urogastrone/URG, Human, Recombinant , 重组人胰岛素溶液 (10mg/mL) , MEM非必需氨基酸溶液 (NEAA),100× , 青霉素-链霉素溶液 (双抗),100× , RPMI-1640 培养基
-
Identification of LRRC46 as a novel candidate gene for high myopia (2024-06-11)
期刊:Science China-Life Sciences
影响因子 :8.0
引用产品: 重组人胰岛素溶液(10 mg/mL) , HFSF 细胞 , 人巩膜成纤维细胞完全培养基 , 磷酸盐缓冲液(PBS) 1× , HCE-T 细胞 , 特级胎牛血清 , EGF/Urogastrone/URG, Human, Recombinant
-
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D (2024-01-10)
期刊:JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1021/acs.jmedchem.3c01622
影响因子 :7.3
引用产品: CAL-62 细胞 , HCT 116 细胞 , AGS 细胞 , 重组人胰岛素溶液 (10mg/mL)
-
Tanshinone I improves TNBC chemosensitivity by suppressing late-phase autophagy through AKT/p38 MAPK signaling pathway (2024-07-02)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2024.117037
影响因子 :6.9
引用产品: HCC1937 细胞 , HCC1954 细胞 , 重组人胰岛素溶液(10 mg/mL)
-
Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice (2024-04-14)
期刊:Nutrients
影响因子 :5.9
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
Sorghum Prolamin Scaffolds-Based Hybrid Cultured Meat with Enriched Sensory Properties (2024-10-09)
期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 :5.7
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
Therapeutic evaluation of glycoprotein hormone β5/α2 in reducing obesity and metabolic dysfunctions in genetically obese ob/ob mice (2024-12-10)
期刊:BIOCHEMICAL PHARMACOLOGY
影响因子 :5.3
引用产品: 特级胎牛血清 , D-葡萄糖溶液(200 g/L) , 重组人胰岛素溶液(10 mg/mL)
-
Weighted Gene Co-Expression Network Based on Transcriptomics: Unravelling the Differentiation Dynamics of 3T3-L1 Preadipocytes and the Regulatory Mechanism of Protopanaxatriol (2024-11-14)
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :4.9
引用产品: 3T3-L1 细胞 , 重组人胰岛素溶液(10 mg/mL)
-
Pirfenidone inhibits CCL2-mediated Treg chemotaxis induced by palbociclib and fulvestrant in HR+/HER2− breast cancer (2024-09-05)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2024.113059
影响因子 :4.8
引用产品: MEM 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液(双抗),100× , L-丙氨酰-L-谷氨酰胺溶液(GlutaMAX)(200 mM),100× , 重组人胰岛素溶液(10 mg/mL) , MA-891 细胞 , RPMI-1640 培养基
-
Atorvastatin exerts a preventive effect against steroid-induced necrosis of the femoral head by modulating Wnt5a release (2024-07-07)
期刊:ARCHIVES OF TOXICOLOGY
DOI:10.1007/s00204-024-03817-z
影响因子 :4.8
引用产品: 大鼠骨髓间充质干细胞 , 重组人胰岛素溶液(10 mg/mL)
-
Exogenous Nucleotides Ameliorate Insulin Resistance Induced by Palmitic Acid in HepG2 Cells through the IRS-1/AKT/FOXO1 Pathways (2024-06-07)
期刊:Nutrients
影响因子 :4.8
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
The role of RUNX1/NF-κB in regulating PVAT inflammation in aortic dissection (2024-04-30)
期刊:Scientific Reports
DOI:10.1038/s41598-024-60737-9
影响因子 :4.6
引用产品: A7r5细胞专用培养基 , RAW 264.7细胞专用培养基 , RAW 264.7 细胞 , 3T3-L1细胞专用培养基 , A7r5 细胞 , 3T3-L1 细胞 , 重组人胰岛素溶液(10 mg/mL)
-
Regulation of corticosteroid-binding globulin release in murine leydig tumor cell line mLTC-1 by luteinizing hormone and interleukin-6 (2024-09-20)
期刊:ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影响因子 :3.8
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
LncRNA HIF1A-AS2 promotes triple-negative breast cancer progression and paclitaxel resistance via MRPS23 protein (2024-08-16)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e36469
影响因子 :3.4
引用产品: 重组人胰岛素溶液(10 mg/mL) , MDA-MB-231 细胞 , MCF 10A 细胞 , MCF 10A细胞专用培养基 , BT-549 细胞
-
Citrus polymethoxyflavones degrade estrogen receptor-alpha (ERα) and combine with tamoxifen for the treatment of estrogen receptor-positive breast cancer (2024-06-15)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e33104
影响因子 :3.4
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells: BRCC3 promotes the proliferation and metastasis of TNBC (2024-03-07)
期刊:ACTA BIOCHIMICA ET BIOPHYSICA SINICA
影响因子 :3.3
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
Anti-adipogenesis and anti-obesity potential of alliin mediated by modulating glycolipid metabolism via activating PPARγ signaling (2024-06-03)
期刊:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI:10.1007/s00210-024-03181-w
影响因子 :3.1
引用产品: 3T3-L1 细胞 , 重组人胰岛素溶液(10 mg/mL)
-
A disulfidptosis-related lncRNAs cluster to forecast the prognosis and immune landscapes of ovarian cancer (2024-07-09)
期刊:Frontiers in Genetics
DOI:10.3389/fgene.2024.1397011
影响因子 :2.8
引用产品: NIH:OVCAR-3 [OVCAR3] 细胞 , 青霉素-链霉素溶液(双抗),100× , 重组人胰岛素溶液(10 mg/mL)
-
The Application of Duck Embryonic Fibroblasts CCL-141 as a Cell Model for Adipogenesis (2024-10-15)
期刊:Animals
影响因子 :2.7
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
SEMA7A as a Novel Prognostic Biomarker and Its Correlation with Immune Infiltrates in Breast Cancer (2024-09-14)
期刊:International Journal of General Medicine
影响因子 :2.1
引用产品: SK-BR-3 [SKBR3] 细胞 , MCF 10A细胞专用培养基 , MCF 10A 细胞 , BT-549 细胞 , EGF/Urogastrone/URG, Human, Recombinant , MCF7 [MCF-7] 细胞 , 重组人胰岛素溶液(10 mg/mL) , 马血清
-
Single-cell RNA sequencing and bulk sequencing reveal the immunosuppressive role of malignant cells in triple-negative breast cancer (2024-06-13)
期刊:Gene Reports
DOI:10.1016/j.genrep.2024.101952
影响因子 :1.0
引用产品: EGF/Urogastrone/URG, Human, Recombinant , 重组人胰岛素溶液(10 mg/mL) , 马血清 , DMEM/F12 培养基
-
Characterization of Cancer Cell Mechanics by Measuring Active Deformation Behavior (2023-09-29)
期刊:Small Methods
影响因子 :12.4
引用产品: DMEM/F12 培养基 , 马血清 , EGF/Urogastrone/URG, Human, Recombinant , 重组人胰岛素溶液 (10mg/mL) , MEM非必需氨基酸溶液 (NEAA),100× , Hela 细胞 , MCF 10A 细胞
-
Lipid-lowering activity and underlying mechanism of glycosylated peptide–calcium chelate prepared by transglutaminase pathway (2023-10-17)
期刊:Food Frontiers
DOI:10.1002/fft2.320
影响因子 :9.9
引用产品: 重组人胰岛素溶液 (10mg/mL)
-
NAD+ supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling (2023-01-23)
期刊:ONCOGENE
DOI:10.1038/s41388-023-02592-y
影响因子 :8.0
引用产品: 重组人胰岛素溶液 (10mg/mL) , MEM (含NEAA) 培养基
-
DNA Nanoribbon-Assisted Intracellular Biosynthesis of Fluorescent Gold Nanoclusters for Cancer Cell Imaging (2023-09-06)
期刊:JACS Au
影响因子 :8.0
引用产品: DMEM/F12 培养基 , 重组人胰岛素溶液 (10mg/mL) , MEM非必需氨基酸溶液 (NEAA),100× , EGF/Urogastrone/URG, Human, Recombinant , 马血清 , MTT溶液 (5mg/mL) , MCF 10A 细胞
-
NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway (2023-06-05)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04236-x
影响因子 :7.4
引用产品: BT-549 细胞 , MDA-MB-231 细胞 , MDA-MB-468 细胞 , MCF7 [MCF-7] 细胞 , MCF 10A 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , 重组人胰岛素溶液 (10mg/mL) , DMEM高糖 培养基
-
Molecular mechanism of Gan-song Yin inhibiting the proliferation of renal tubular epithelial cells by regulating miR-21-5p in adipocyte exosomes (2023-12-01)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
-
Hypoglycemic Effect of Edible Fungi Polysaccharides Depends on Their Metabolites from the Fermentation of Human Fecal Microbiota (2023-12-27)
期刊:Foods
影响因子 :5.2
引用产品: Hep G2 细胞 , 特级胎牛血清 , 重组人胰岛素溶液 (10mg/mL)
-
Z-Guggulsterone Induces Cell Cycle Arrest and Apoptosis by Targeting the p53/CCNB1/PLK1 Pathway in Triple-Negative Breast Cancer (2023-01-03)
期刊:ACS Omega
影响因子 :4.1
引用产品: DMEM/F12 培养基 , 马血清 , EGF/Urogastrone/URG, Human, Recombinant , 重组人胰岛素溶液 (10mg/mL) , MEM非必需氨基酸溶液 (NEAA),100×
-
AXL upregulates c?Myc expression through AKT and ERK signaling pathways in breast cancers (2023-02-08)
期刊:Molecular and Clinical Oncology
影响因子 :1.2
引用产品: MCF7 [MCF-7] 细胞 , MEM (含NEAA) 培养基 , 重组人胰岛素溶液 (10mg/mL) , 特级胎牛血清
-
Three-dimensional layered nanofiber sponge with in situ grown silver- metal organic framework for enhancing wound healing (2022-04-21)
期刊:Chemical Engineering Journal
影响因子 :15.1
-
Knockdown of hepatocyte Perilipin-3 mitigates hepatic steatosis and steatohepatitis caused by hepatocyte CGI-58 deletion in mice (2022-09-15)
期刊:Journal of Molecular Cell Biology
影响因子 :8.2
引用产品: 重组人胰岛素溶液(10 mg/mL) , AML12细胞专用培养基
-
Potentilla bifurca flavonoids effectively improve insulin resistance (2022-11-01)
期刊:European Review for Medical and Pharmacological Sciences
DOI:10.26355/eurrev_202211_30370
影响因子 :3.8
引用产品: 3T3-L1 细胞 , DMEM高糖 培养基 , 青霉素-链霉素溶液 (双抗),100× , 磷酸盐缓冲液 (PBS) 1× , 0.25%胰蛋白酶溶液 (含EDTA,溶于PBS) , 重组人胰岛素溶液 (10mg/mL)
-
Regulation of Atherosclerosis by Toll-Like Receptor 4 Induced by Serum Amyloid 1: A Systematic In Vitro Study (2022-09-15)
期刊:Biomed Research International
影响因子 :3.3
引用产品: 人脐静脉内皮细胞 , MEM非必需氨基酸溶液 (NEAA),100× , 重组人胰岛素溶液 (10mg/mL) , THP-1 细胞
-
Incorporation of a Multi-Valent Aptamer into Electrochemical Biosensors to Achieve an Improved Performance for Thrombin Analysis in Blood Serum (2022-11-21)
期刊:ChemPlusChem
影响因子 :3.2
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
Copper Tannic Acid-Coordinated Metal–Organic Nanosheets for Synergistic Antimicrobial and Antifouling Coatings (2021-02-22)
期刊:ACS Applied Materials & Interfaces
影响因子 :9.5
引用产品: MCF 10A细胞专用培养基 , DMEM/F12 (含HEPES) 培养基 , 马血清 , 重组人胰岛素溶液 (10mg/mL)
-
Macroscopic Supramolecular Assembly Strategy to Construct 3D Biocompatible Microenvironments with Site-Selective Cell Adhesion (2021-06-11)
期刊:ACS Applied Materials & Interfaces
影响因子 :9.5
引用产品: MG-63 细胞 , PC-12 (Undifferentiated) 细胞 , 重组人胰岛素溶液 (10mg/mL) , MEM非必需氨基酸溶液 (NEAA),100× , PUMC-HUVEC-T1 , CCC-SMC-1 细胞
-
Metformin regulates adiponectin signalling in epicardial adipose tissue and reduces atrial fibrillation vulnerability (2020-05-22)
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 :4.5
引用产品: 重组人胰岛素溶液(10 mg/mL)
-
MiR-519d and miR-328-3p Combinatorially Suppress Breast Cancer Progression (2020-12-18)
期刊:OncoTargets and Therapy
影响因子 :4.0
引用产品: Leibovitz's L-15 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , MEM (含NEAA) 培养基 , 重组人胰岛素溶液(10 mg/mL) , McCoy's 5A 培养基 , DMEM/F12 培养基 , McCoy's 5A 培养基 , DMEM/F12 培养基 , MEM 培养基 , 青霉素-链霉素溶液(双抗),100× , 特级胎牛血清 , Leibovitz's L-15 培养基
FAQs
Q:{{item.question}}
A:
产品资料


识别码示意图