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产品概述
名称 | FaDu (人咽鳞癌细胞) (STR鉴定正确) |
别称 | FaDU; FADU |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:6 |
推荐换液频率 | 2-3次/周 |
背景描述 | FaDu细胞株是于1968年从一位印度下咽骨肿瘤患者的钻孔活组织切片中建立的。在FaDu细胞中发现细胞质中含有成束的细丝,并且FaDu细胞分界上的桥粒特别突出。 |
年龄(性别) | 男性;56岁 |
组织来源 | 咽鳞癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 咽癌细胞 |
倍增时间 | ~30 hours |
保藏机构 | ATCC; HTB-43 BCRC; 60214 BCRJ; 0301 DSMZ; ACC-784 |
STR鉴定
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STR位点信息
CSF1PO 12 D2S1338 19 D3S1358 17,18 D5S818 12 D7S820 11,12 D8S1179 13 D13S317 8,9 D16S539 11 D18S51 16 D19S433 14,16 D21S11 31.2 FGA 25 PentaD 11 PentaE 17,19 TH01 8 TPOX 11 vWA 15,17 D6S1043 11,12 D12S391 17,21 D2S441 11 -
STR鉴定图
参考文献
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IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway (2024-01-25)
作者:Peng Liu:1.Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. cqmulp@stu.cqmu.edu.cn. ; Xin Kong:1.Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases, Institute for Viral Hepatitis, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. ; Shijiang Yi:1.Department of Otolaryngology Head and Neck Surgery, the Affiliated Hospital of Guilin Medical University, Guilin, China. ; Ying Chen:1.Department of Traditional Chinese Medicine, the Affiliated Hospital of Guilin Medical University, Guilin, China. ; Wenlong Luo:1.Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. luowenlong163@163.com. ;
期刊:IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway
DOI:10.1186/s12957-023-03274-5
影响因子 :3.2
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Amelioration of gamma irradiation-induced salivary gland damage in mice using melatonin (2023-06-30)
作者:Jingming Ren:1.Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. ; Tong Zhu:1.Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. ; Zhouxuan Wang:1.Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. ; Lu Lu:1.Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. ; Saijun Fan:1.Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Scie
期刊:Amelioration of gamma irradiation-induced salivary gland damage in mice using melatonin
影响因子 :10.3
引用产品: Hank's平衡盐溶液 (HBSS),含钙、镁,不含酚红 , FaDu 细胞
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PD-L1 Exon 3 Is a Hidden Switch of Its Expression and Function in Oral Cancer Cells (2023-05-03)
作者:Lingyan Yan:1.The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China. ; Yanan Sun:1.The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China. ; Jihua Guo:1.The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China. ; 2.Department of Endodontics, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China. ; Rong Jia:1.The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan Uni
期刊:PD-L1 Exon 3 Is a Hidden Switch of Its Expression and Function in Oral Cancer Cells
影响因子 :5.6
引用产品: FaDu 细胞 , U-2 OS [U2OS] 细胞 , Ca Ski 细胞
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An anti-PD-1 antisense oligonucleotide promotes the expression of soluble PD-1 by blocking the interaction between SRSF3 and an exonic splicing enhancer of PD-1 exon 3 (2023-12-04)
作者:Xu Wang:1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University Wuhan 430072, China. Electronic address: wangxu@whu.edu.cn. ; Lingyan Yan:1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University Wuhan 430072, China. ; Jihua Guo:1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University Wuhan 430072, China; Department of Endodontics, School & Hospital of Stomatology, Wuhan University, Wuhan 430072, China. Electronic address: jihuaguo@whu.edu.cn. ; Rong Jia:1.State Key Laboratory of Oral
期刊:An anti-PD-1 antisense oligonucleotide promotes the expression of soluble PD-1 by blocking the interaction between SRSF3 and an exonic splicing enhancer of PD-1 exon 3
DOI:10.1016/j.intimp.2023.111280
影响因子 :5.6
引用产品: MOLT-4 细胞 , FaDu 细胞 , Ca Ski 细胞 , HCT 116 细胞
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Homeobox-D 1 and FTO form a transcriptional–epigenetic feedback loop to promote head and neck cancer proliferation (2023-09-01)
作者:Chunyan Zhang:1.Department of Clinical Laboratory, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China. ; Linsen Xie:1.Department of Clinical Laboratory, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China. ; Zhen Lin:1.Department of Clinical Laboratory, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China. ;
期刊:Homeobox-D 1 and FTO form a transcriptional–epigenetic feedback loop to promote head and neck cancer proliferation
影响因子 :3.9
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Long Non-coding RNA Linc01224 Regulates Hypopharyngeal Squamous Cell Carcinoma Growth Through Interactions with miR-485-5p and IGF2BP3 (2023-09-18)
作者:Lai Wei:1.Department of Otolaryngology, The Eighth Affiliated Hospital of Sun Yat-sen University, 518033, Shenzhen, China. ; 2.Department of Otolaryngology, Affiliated Zhongshan Hospital of Dalian University, 116000, Dalian, China. ; Yuanhang Wu:1.Department of Oncology, The First Affiliated Hospital of Dalian Medical University, 116000, Dalian, China. ; Sisi Cai:1.Department of Otolaryngology, Affiliated Zhongshan Hospital of Dalian University, 116000, Dalian, China. ; Yulan Qin:1.Department of Otolaryngology, Affiliated Zhongshan Hospital of Dalian University, 116000, Dalian, China. ; Shuangchun Xing:1.Department of Otolaryngology, The First Affiliated Hospital of Dalian Medical University, 116000, Dalian, China. ; Zhiqiang Wang:1.Department of Otolaryngology, The Eighth Affiliated Hospital of Sun Yat-sen University, 518033, Shenzhen, China. ; 2.Department of Otolaryngology, Affiliated Zhongshan Hospital of Dalian University, 116000, Dalian, China. ;
期刊:Long Non-coding RNA Linc01224 Regulates Hypopharyngeal Squamous Cell Carcinoma Growth Through Interactions with miR-485-5p and IGF2BP3
影响因子 :3.9
引用产品: FaDu 细胞
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Identification of a distinct tumor endothelial cell-related gene expression signature associated with patient prognosis and immunotherapy response in multiple cancers (2023-05-25)
作者:Xianhua Zhuo:1.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. ; 2.Department of Otolaryngology, Head and Neck Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. ; Cheng Huang:1.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. ; 2.Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. ; Liangping Su:1.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. ; 2.Medical Research Center, S
期刊:Identification of a distinct tumor endothelial cell-related gene expression signature associated with patient prognosis and immunotherapy response in multiple cancers
DOI:10.1007/s00432-023-04848-2
影响因子 :3.6
引用产品: FaDu 细胞 , Hep G2 细胞 , A549 [A-549] 细胞
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Stathmin1 promotes lymph node metastasis in hypopharyngeal squamous cell carcinoma via regulation of HIF‑1α/VEGF‑A axis and MTA1 expression (2023-02-03)
作者:Yuqian Wu:1.Cancer Center, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China. ; Qin Liu:1.Cancer Center, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China. ; Jiaojiao Tong:1.Cancer Center, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China. ; Chunhui Hu:1.Cancer Center, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China. ; Dianshui Sun:1.Cancer Center, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China. ;
期刊:Stathmin1 promotes lymph node metastasis in hypopharyngeal squamous cell carcinoma via regulation of HIF‑1α/VEGF‑A axis and MTA1 expression
影响因子 :1.2
引用产品: FaDu 细胞 , MEM (含NEAA) 培养基
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Application of nanogold-cisplatin drug delivery system in laryngeal cancer chemoradiotherapy (2023-11-01)
作者:Xing, Guosheng: 1.Medical Imaging Diagnosis Teaching and Research Office, Henan Medical College, Zhengzhou, 451191, Henan, PR China; Kong, Ruihua: 1.Medical Imaging Diagnosis Teaching and Research Office, Henan Medical College, Zhengzhou, 451191, Henan, PR China; Yang, Shuli: 1.Medical Imaging Diagnosis Teaching and Research Office, Henan Medical College, Zhengzhou, 451191, Henan, PR China; Ma, Ruixue: 1.Medical Imaging Diagnosis Teaching and Research Office, Henan Medical College, Zhengzhou, 451191, Henan, PR China; Sun, Zhiguo: 1.Medical Imaging Diagnosis Teaching and Research Office, Henan Medical College, Zhengzhou, 451191, Henan, PR China;
期刊:Application of nanogold-cisplatin drug delivery system in laryngeal cancer chemoradiotherapy
影响因子 :0.7
引用产品: FaDu 细胞 , FaDu细胞专用培养基
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Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu) (2003-02-20)
作者:Xin Gao:1.Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, People's Republic of China. ; Xinlong Fan:1.Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, People's Republic of China. ; Wei Zeng:1.Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, People's Republic of China. ; Jiwang Liang:1.Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, People's Republic of China. ; Nan Guo:1.Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, People's Republic of China. ; Xiao Yang:1.Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, She
期刊:Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu)
DOI:10.1080/21655979.2022.2051266
影响因子 :4.9
引用产品: FaDu 细胞
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Identification and in vitro validation of prognostic lncRNA signature in head and neck squamous cell carcinoma (2010-01-20)
作者:Jian Wang:1.Department of Oral and Maxillofacial Surgery, The Affiliated Stomatology Hospital of The First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uyghur Autonomous Region, Urumqi, 830054, P.R. China. ; 2.Xinjiang Uygur Autonomous Region Institute of Stomatology, Xinjiang Uyghur Autonomous Region, Urumqi, 830054, P.R. China. ; Qinjiang Bian:1.Department of Maxillofacial Surgery, Gansu Provincial Hospital, Lanzhou, Gansu province, 730000, P.R. China. ; Jialin Liu:1.Xinjiang Uygur Autonomous Region Institute of Stomatology, Xinjiang Uyghur Autonomous Region, Urumqi, 830054, P.R. China. ; 2.Department of Prosthodontics, The Affiliated Stomatology Hospital of The First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uyghur Autonomous Region, Urumqi, 830054, P.R. China. ; Adili Moming:1.Department of Oral and Maxillofacial Surgery, The Affiliated Stomatology Hospital of The First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uyghur Autonom
期刊:Identification and in vitro validation of prognostic lncRNA signature in head and neck squamous cell carcinoma
DOI:10.1080/21655979.2021.1995577
影响因子 :4.9
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Metformin Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma through Circ_0003214-Mediated MiR-489-3p-ADAM10 Pathway (2007-01-20)
作者:Xiaoqiang Chen:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ; Chen Li:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ; Wei Chen:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ; Shuchun Lin:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ; Xuehan Yi:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ; Qin Lin:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ; Hao Xu:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ; Desheng Wang:1.Department of Otolaryngology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. ;
期刊:Metformin Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma through Circ_0003214-Mediated MiR-489-3p-ADAM10 Pathway
影响因子 :4.5
引用产品: FaDu 细胞
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The miR‑136‑5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells (2002-01-20)
作者:Bo Yang:1.Department of Otorhinolaryngology Head and Neck Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China. ; Jian Zang:1.Department of Otorhinolaryngology Head and Neck Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China. ; Weili Yuan:1.Department of Oral and Maxillofacial Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning 110032, P.R. China. ; Xuejun Jiang:1.Department of Otorhinolaryngology Head and Neck Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China. ; Fang Zhang:1.Department of Otorhinolaryngology Head and Neck Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning 110032, P.R. China. ;
期刊:The miR‑136‑5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells
影响因子 :2.7
引用产品: FaDu 细胞
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Downregulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR‐455‐5p (2011-00-20)
作者:Jingjing Wu:1.Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. ; Yong Li:1.Department of General Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. ; Jian Liu:1.Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. ; Yanzhi Xu:1.Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. ;
期刊:Downregulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR‐455‐5p
DOI:10.1002/jgm.3293
影响因子 :3.5
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