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MDA-MB-436 (人乳腺癌细胞) (STR鉴定正确)
货号：CL-0383
规格：1×10⁶cells/T25培养瓶
价格： ￥1600
生长培养基：Leibovitz's L-15＋10μg/ml Insulin＋16μg/ml Glutathione＋15% FBS＋1% P/S
产品概述
| 名称 | MDA-MB-436 (人乳腺癌细胞) (STR鉴定正确) |
| 别称 | MDA MB 436; MDA-Mb-436; MDA-MB436; MDAMB436; MDA-436; MDA436; MD Anderson-Metastatic Breast-436 |
| 种属 | 人类 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 多角形 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，100%, 温度：37℃
|
| 培养方案B（可选） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 1.该细胞推荐使用Leibovitz's L-15培养基进行培养，Leibovitz's L-15不可以通入二氧化碳，会产生细胞毒性；2.如您没有无二氧化碳的培养箱，可使用DMEM替代Leibovitz's L-15，使用DMEM培养基时即可正常通入5%二氧化碳；3.配套专用培养基默认Leibovitz's L-15配置，如需DMEM配方，请联系销售下单备注更改。 |
| 背景描述 | MDA-MB-436细胞源于一名43岁患有乳腺腺癌女性的胸腔积液；MDA-MB-436细胞呈多形性，大多数细胞在间接免疫荧光染色时呈现与抗微管抗体的强烈反应。 |
| 年龄（性别） | 女性，43岁 |
| 组织来源 | 乳腺腺癌胸水转移灶 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 乳腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | No, in immunosuppressed mice.Yes, in semisolid medium. |
| 基因表达情况 | tubulin; actin |
| 保藏机构 | ATCC; HTB-130 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 23 D3S1358 18 D5S818 13 D7S820 10 D8S1179 10,14 D13S317 10 D16S539 9,11 D18S51 12 D19S433 13 D21S11 30,31.2 FGA 24 PentaD 9 PentaE 10,12 TH01 9.3 TPOX 8 vWA 14,20 D6S1043 11 D12S391 20 D2S441 10 -
STR鉴定图
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参考文献
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The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation (2024-01-22)
作者：Weijun Wu:1.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China; Department of Oncology Radiotherapy, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China. ; Wenjing Wu:1.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China; Department of Breast Oncology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ; Yingshi Zhou:1.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, G
期刊：The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation
影响因子 ：4.8
引用产品： MCF 10A 细胞 , HCC1806 细胞 , HCC1937 细胞 , MDA-MB-468 细胞 , BT-20 细胞 , Hs 578T 细胞 , MDA-MB-436 细胞 , MCF 10A细胞专用培养基 , HCC1806细胞专用培养基 , HCC1937细胞专用培养基 , MDA-MB-468细胞专用培养基 (L15) , BT-20细胞专用培养基 , Hs 578T细胞专用培养基 , MDA-MB-436细胞专用培养基 (L15)
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Identification of TFR2 as a novel ferroptosis‑related gene that serves an important role in prognosis and progression of triple‑negative breast cancer (2023-12-05)
作者：Yan Yang:1.Department of Laboratory Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; 2.School of Laboratory Medicine, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; 3.School of Forensic Medicine, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; Jie Du:1.School of Laboratory Medicine, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; Yun-Fei Huang:1.School of Laboratory Medicine, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; Wei He:1.School of Laboratory Medicine, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; Li Liu:1.Clinical Medical College, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; Dan Li:1.Clinical Medical College, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ; Rui Chen:1.Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China. ;
期刊：Identification of TFR2 as a novel ferroptosis‑related gene that serves an important role in prognosis and progression of triple‑negative breast cancer
影响因子 ：2.9
引用产品： MCF 10A 细胞 , T-47D 细胞 , SK-BR-3 [SKBR3] 细胞 , BT-549 细胞 , MDA-MB-468 细胞 , MDA-MB-436 细胞 , MDA-MB-231 细胞 , 马血清 , MEM非必需氨基酸溶液 (NEAA)，100×
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LncRNA MAGI2-AS3-Encoded Polypeptide Restrains the Proliferation and Migration of Breast Cancer Cells (2023-06-26)
作者：Zhiwei Zhang:1.Department of Oncology, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ; Yanli Yi:1.Department of Breast Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ; Zai Wang:1.Science and Education Division, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ; Haoyun Zhang:1.Department of Breast Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ; Yanchun Zhao:1.Department of Breast Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ; Ruijing He:1.Department of Breast Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ; Yan Luo:1.Department of Reproductive Genetic, Hebei General Hospital, Shijiazhuang, 050000, Hebei, China. ; Zhiqiang Cui:1.Department of Breast Surgery, Affiliated Hospital of Hebei University of Engineering,
期刊：LncRNA MAGI2-AS3-Encoded Polypeptide Restrains the Proliferation and Migration of Breast Cancer Cells
DOI：10.1007/s12033-023-00801-3
影响因子 ：2.6
引用产品： MCF7 [MCF-7] 细胞 , MDA-MB-436 细胞 , 293T [HEK-293T] 细胞 , RPMI-1640 培养基 , DMEM高糖 培养基
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Inhibition of glycolysis represses the growth and alleviates the endoplasmic reticulum stress of breast cancer cells by regulating TMTC3 (2023-04-10)
作者：Xue Hu:1.Department of Breast Surgery, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, 130033, China. ; Baoliang Guo:1.Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin City, Heilongjiang Province, China. ; Tong Sun:1.Department of Breast Surgery, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, 130033, China. ; Wan Wang:1.Department of Breast Surgery, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Avenue, Nanguan District, Changchun City, Jilin Province, 130033, China. ;
期刊：Inhibition of glycolysis represses the growth and alleviates the endoplasmic reticulum stress of breast cancer cells by regulating TMTC3
影响因子 ：2.1
引用产品： MCF 10A 细胞 , MCF7 [MCF-7] 细胞 , MDA-MB-231 细胞 , MDA-MB-436 细胞 , SK-BR-3 [SKBR3] 细胞 , DMEM/F12 培养基 , 马血清 , MEM非必需氨基酸溶液 (NEAA)，100× , 青霉素-链霉素溶液 (双抗)，100× , RPMI-1640 (ATCC改良) 培养基 , Leibovitz's L-15 培养基 , McCoy's 5A 培养基 , 特级胎牛血清
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FEZF2 inhibits the growth of triple-negative breast cancer cells through EZH2/PD-L1 and enhances anti-tumor immunity in vivo (2023-06-19)
作者：Wenyu Li: 1.The Fifth Ward of the Department of Tumor Chemotherapy, The First Affiliated Hospital of USTC, No. 107 Huanhu East Road, Anhui, Hefei, China; Hu Liu: 1.The Fifth Ward of the Department of Tumor Chemotherapy, The First Affiliated Hospital of USTC, No. 107 Huanhu East Road, Anhui, Hefei, China; Wenjuan Li: 1.The Fifth Ward of the Department of Tumor Chemotherapy, The First Affiliated Hospital of USTC, No. 107 Huanhu East Road, Anhui, Hefei, China; Qiujun Zhang: 1.The Fifth Ward of the Department of Tumor Chemotherapy, The First Affiliated Hospital of USTC, No. 107 Huanhu East Road, Anhui, Hefei, China; Qianyu Zhang: 1.The Fifth Ward of the Department of Tumor Chemotherapy, The First Affiliated Hospital of USTC, No. 107 Huanhu East Road, Anhui, Hefei, China; Dandan Hu: 1.The Fifth Ward of the Department of Tumor Chemotherapy, The First Affiliated Hospital of USTC, No. 107 Huanhu East Road, Anhui, Hefei, China;
期刊：FEZF2 inhibits the growth of triple-negative breast cancer cells through EZH2/PD-L1 and enhances anti-tumor immunity in vivo
DOI：10.1007/s13273-023-00368-9
影响因子 ：1.7
引用产品： MCF 10A 细胞 , DMEM/F12 培养基 , 马血清 , 青霉素-链霉素溶液 (双抗)，100× , MDA-MB-231 细胞 , MDA-MB-468 细胞 , DMEM高糖 培养基 , BT-549 细胞 , RPMI-1640 培养基 , MDA-MB-436 细胞
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DNAJB4 identified as a potential breast cancer marker: evidence from bioinformatics analysis and basic experiments (2012-00-20)
作者：Linlong Mo:1.Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, China. ; Jiayou Liu:1.Human Anatomy Department of School of Basic Medical Sciences, North Sichuan Medical College, Nanchong, China. ; Ziquan Yang:1.Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, China. ; Xun Gong:1.Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, China. ; Fanlun Meng:1.Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, China. ; Rongyang Zou:1.Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, China. ; Lingmi Hou:1.Department of Breast and Thyroid Surgery, Hepatobiliary and pancreatic institution, Affiliated Hospital of North Sichuan Medical College, Nanchong, China. ; Fang Fang:1.Department of Thyroid and Breast Surgery, The Fir
期刊：DNAJB4 identified as a potential breast cancer marker: evidence from bioinformatics analysis and basic experiments
影响因子 ：1.8
引用产品： MCF 10A 细胞 , MDA-MB-231 细胞 , MDA-MB-436 细胞
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