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产品概述
名称 | DLD-1 (人结直肠腺癌上皮细胞) (STR鉴定正确) |
别称 | DLD 1; DLD1; CoCL3 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:8 |
推荐换液频率 | 2-3次/周 |
背景描述 | DLD-1细胞是由D·L·Dexter和其同事于1977-1979年分离的两株结直肠腺癌细胞株中的一株。在ATCC和其它地方进行的DNA指纹鉴定和染色体组型分析表明DLD-1细胞与HCT-15细胞相似,说明这两者是来自同一个人的不同克隆。DLD-1细胞和HCT-15细胞的遗传起源可通过DNA指纹鉴定证实,但染色体组型分析显示它们缺乏染色体标记一致改变或数目上一致改变。DLD-1细胞的CSAp阴性(CSAp-),p53抗原表达呈阳性(p53抗原产生了一个C→T点突变导致241位的Ser→Phe)。DLD-1细胞角蛋白免疫过氧化物酶染色阳性,癌基因c-myc、K-ras、H-ras、N-ras、myb、sis和fos的表达呈阳性,癌基因N-myc的表达未做检测。DLD-1细胞表达肿瘤特异性核基质蛋白CC-2、CC-3、CC-4、CC-5和CC-6。1979年提交到ATCC的DLD-1细胞代数不明且污染了支原体,其后经过12周多种抗生素联合培养处理,处理之后每周用Hoechst染色和标准培养法检测。其后连续11个月不加抗生素培养,DLD-1细胞所有的检测呈阴性。 |
年龄(性别) | 男性;成人 |
组织来源 | 结直肠腺癌上皮细胞 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肠癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~24-48 hours |
致瘤性 | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells). |
抗原表达情况 | Blood Type O.The cells are weakly positive for keratins and vimentin.The cells are positive for keratin by immunoperoxidase staining.DLD-1 cells are positive for p53 antigen expression (the p53 antigen produced has a C -> T |
基因表达情况 | carcinoembryonic antigen (CEA) 0.5 ng/10^6 cells/10 days; colon antigen 3. |
保藏机构 | ATCC; CCL-221 BCRC; 60132 DSMZ; ACC-278 ECACC; 90102540 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 11,12 D2S1338 17,25 D3S1358 17 D5S818 13 D7S820 10,12 D8S1179 15 D13S317 8,11 D16S539 12,13 D18S51 11,17 D19S433 14,16 D21S11 29,32.2 FGA 22 PentaD 9,14 PentaE 7,14 TH01 7,9.3 TPOX 8,11 vWA 18,19 D6S1043 11,13 D12S391 19,22 D2S441 13,15 -
STR鉴定图
参考文献
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Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis (2024-01-17)
作者:Can Cheng:1.Department of General Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. ; 2.Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. ; Hanhui Yao:1.Department of General Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. ; 2.Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. ; Heng Li:1.Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and T
期刊:Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis
DOI:10.1016/j.apsb.2024.01.006
影响因子 :14.5
引用产品: 特级胎牛血清 , LoVo 细胞 , HT-29 细胞 , HCT 116 细胞 , SW620 细胞 , RKO 细胞 , DLD-1 细胞 , HCT-8 [HRT-18] 细胞
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Norcantharidin Sensitizes Colorectal Cancer Cells to Radiotherapy via Reactive Oxygen Species–DRP1-Mediated Mitochondrial Damage (2024-03-14)
作者:Qiong Xu:1.Department of Oncology, Tianjin Union Medical Center, Nankai University, Tianjin 300350, China. ; 2.School of Medicine, Nankai University, Tianjin 300350, China. ; 3.School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301600, China. ; Heng Zhang:1.Department of Oncology, Tianjin Union Medical Center, Nankai University, Tianjin 300350, China. ; Haoren Qin:1.School of Medicine, Nankai University, Tianjin 300350, China. ; Huaqing Wang:1.Department of Oncology, Tianjin Union Medical Center, Nankai University, Tianjin 300350, China. ; Hui Wang:1.Department of Oncology, Tianjin Union Medical Center, Nankai University, Tianjin 300350, China. ;
期刊:Norcantharidin Sensitizes Colorectal Cancer Cells to Radiotherapy via Reactive Oxygen Species–DRP1-Mediated Mitochondrial Damage
影响因子 :7.0
引用产品: DLD-1 细胞
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METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1 (2024-01-24)
作者:Rui Yang:1.Department of Oncology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. ; Cheng Yang:1.Department of Oncology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. ; Danjie Su:1.Department of Obstetrics and Gynecology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. ; Yang Song:1.Department of Oncology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. ; Jie Min:1.Department of Oncology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. ; Zhixin Qian:1.Department of Oncology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. ; Xiangjing Shen:1.Department of Oncology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. ; Junqiang Li:1.Department of Oncology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi, China. jjunqiang@126.com. ; Haichuan Su:1.Departm
期刊:METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1
DOI:10.1038/s41417-024-00731-5
影响因子 :6.4
引用产品: HCT 116 细胞 , DLD-1 细胞 , 293T [HEK-293T] 细胞
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SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway (2024-03-08)
作者:Bi-Xia Liu:1.Department of Gastroenterology, Digestive Disease Hospital, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang 330000, Jiangxi, China; Department of Gastroenterology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330000, Jiangxi, China. ; Yang Xie:1.Department of Gastroenterology, Digestive Disease Hospital, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang 330000, Jiangxi, China. ; Jiayu Zhang:1.Huankui Academy of Nanchang University, Nanchang 330000, Jiangxi, China. ; Shuyan Zeng:1.Huankui Academy of Nanchang University, Nanchang 330000, Jiangxi, China. ; Jun Li:1.Department of Gastroenterology, Digestive Disease Hospital, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang 330000, Jiangxi, China. ; Qing Tao:1.Department of Gastroenterology, Digestive
期刊:SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway
DOI:10.1016/j.intimp.2024.111759
影响因子 :5.6
引用产品: DLD-1 细胞 , SW480 [SW-480] 细胞 , NCM460 细胞
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Integrated Multi-omics Analyses Identify CDCA5 as a Novel Biomarker Associated with Alternative Splicing, Tumor Microenvironment, and Cell Proliferation in Colon Cancer Via Pan-cancer Analysis (2024-01-01)
作者:Xinyue Bao:1.Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ; Xin Leng:1.Department of Urology, Affiliated Kunshan Hospital of Jiangsu University, Suzhou215300, China. ; Tianyu Yu:1.Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ; Junzheya Zhu:1.Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ; Yunhan Zhao:1.Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ; Tenzindrogar:1.Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ; Zhiluo Yang:1.Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ; Shaobo Wu:1.Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, C
期刊:Integrated Multi-omics Analyses Identify CDCA5 as a Novel Biomarker Associated with Alternative Splicing, Tumor Microenvironment, and Cell Proliferation in Colon Cancer Via Pan-cancer Analysis
影响因子 :3.9
引用产品: DLD-1 细胞
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Mollugin suppresses proliferation and drives ferroptosis of colorectal cancer cells through inhibition of insulin-like growth factor 2 mRNA binding protein 3/glutathione peroxidase 4 axis (2023-09-05)
作者:Wei Wang:1.Department of Integrated Traditional Chinese and Western Medicine, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang 110042, P.R. China. ; Lijiang Zhou:1.Department of Oncology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, P.R. China. ; Xinyu Zhang:1.Department of Integrated Traditional Chinese and Western Medicine, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang 110042, P.R. China. ; Zheng Li:1.Department of Integrated Traditional Chinese and Western Medicine, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang 110042, P.R. China. Electronic address: fox_dl1984@163.com. ;
期刊:Mollugin suppresses proliferation and drives ferroptosis of colorectal cancer cells through inhibition of insulin-like growth factor 2 mRNA binding protein 3/glutathione peroxidase 4 axis
DOI:10.1016/j.biopha.2023.115427
影响因子 :7.5
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Identification and validation of a novel prognosis model based on m5C-related long non-coding RNAs in colorectal cancer (2023-09-05)
作者:Ziyang Di:1.Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China. ; 2.Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China. ; Gaoran Xu:1.Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China. ; 2.Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China. ; Zheyu Ding:1.Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China. ; 2.Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China. ; Chengxin Li:1.Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China. ; 2.Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China. ; Jialin Song:1.Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China. ; 2.Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China. ; Guoquan Huang:1.Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Chi
期刊:Identification and validation of a novel prognosis model based on m5C-related long non-coding RNAs in colorectal cancer
DOI:10.1186/s12935-023-03025-2
影响因子 :5.8
引用产品: NCM460 细胞 , SW620 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , DLD-1 细胞 , LoVo 细胞 , HT-29 细胞
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Copine 7 promotes colorectal cancer proliferation through PKM2 interaction and MAPK signaling pathway (2023-07-04)
作者:Tianwen Yu:1.Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, China. ; 2.The Hunan Provincial Key Lab of Precision Diagnosis and Treatment for Gastrointestinal Tumor, Xiangya Hospital, Central South University, Changsha, China. ; 3.International Joint Research Center of Minimally Invasive Endoscopic Technology Equipment and Standardization, Xiangya Hospital, Central South University, Changsha, China. ; Changhao Huang:1.The Hunan Provincial Key Lab of Precision Diagnosis and Treatment for Gastrointestinal Tumor, Xiangya Hospital, Central South University, Changsha, China. ; 2.Department of Organ Transplantation Center, Xiangya Hospital, Central South University, Changsha, China. ; Chen Lai:1.The Hunan Provincial Key Lab of Precision Diagnosis and Treatment for Gastrointestinal Tumor, Xiangya Hospital, Central South University, Changsha, China. ; 2.International Joint Research Center of Minimally Invasive Endoscopic Technology Equipment and
期刊:Copine 7 promotes colorectal cancer proliferation through PKM2 interaction and MAPK signaling pathway
影响因子 :4.7
引用产品: 293 [HEK-293] 细胞 , HCT 116 细胞 , DLD-1 细胞 , McCoy's 5A 培养基 , 特级胎牛血清 , RPMI-1640 培养基 , DMEM高糖 培养基
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RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer (2023-07-27)
作者:Shi-Cheng Liu:1.Department of Colorectal Surgery, the Third Affiliated Hospital of Kunming Medical University (the Tumor Hospital of Yunnan), China. ; Le-Lan Gong:1.Department of Colorectal Surgery, the Third Affiliated Hospital of Kunming Medical University (the Tumor Hospital of Yunnan), China. ; Feng-Chang Huang:1.Department of Oncology, the First Affiliated Hospital of Kunming Medical University, China. ; Ning Xu:1.Department of Oncology, the First Affiliated Hospital of Kunming Medical University, China. ; Ke-Xin Yang:1.Department of Colorectal Surgery, the Third Affiliated Hospital of Kunming Medical University (the Tumor Hospital of Yunnan), China. ; Xi-Hong Liu:1.Department of Oncology, the First Affiliated Hospital of Kunming Medical University, China. ; Wen-Liang Li:1.Department of Colorectal Surgery, the Third Affiliated Hospital of Kunming Medical University (the Tumor Hospital of Yunnan), China. Electronic address: liwenliang@kmmu.edu.cn. ;
期刊:RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer
影响因子 :2.8
引用产品: DLD-1 细胞 , HT-29 细胞 , SW480 [SW-480] 细胞
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Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA (2022-12-15)
作者:Chi Jin:1.Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China. ; 2.The First School of Clinical Medicine, Nanjing Medical University, Nanjing, China. ; 3.The Colorectal Institute of Nanjing Medical University, Nanjing, China. ; Tuo Wang:1.Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China. ; 2.The First School of Clinical Medicine, Nanjing Medical University, Nanjing, China. ; 3.The Colorectal Institute of Nanjing Medical University, Nanjing, China. ; Dongsheng Zhang:1.Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China. ; 2.The First School of Clinical Medicine, Nanjing Medical University, Nanjing, China. ; 3.The Colorectal Institute of Nanjing Medical University, Nanjing, China. ; Peng Yang:1.Department of
期刊:Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA
DOI:10.1186/s13046-022-02551-7
影响因子 :12.7
引用产品: 293T [HEK-293T] 细胞 , NCM460 细胞 , SW480 [SW-480] 细胞 , DLD-1 细胞 , HT-29 细胞 , RKO 细胞 , HCT 116 细胞
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Critical role of guanylate binding protein 5 in tumor immune microenvironment and predictive value of immunotherapy response (2022-09-30)
作者:Xiang Li:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Dan Song:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Song Su:1.The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China. ; Xiaobo He:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Fengyu Cao:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Chao Yang:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Kai Li:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Shuoyang Huang:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Changhua Li:1.Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China. ; Chenhong Wang:1.Department of Gastrointestinal Surgery, Renmin
期刊:Critical role of guanylate binding protein 5 in tumor immune microenvironment and predictive value of immunotherapy response
影响因子 :4.8
引用产品: DLD-1 细胞
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CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway (2022-08-15)
作者:Xiaolong Zhang:1.Department of General Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China. ; Lifei Tian:1.Department of General Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China. ; Zeyu Li:1.Department of General Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China. ; Ruiting Liu:1.Department of General Surgery, Shaanxi Provincial People's Hospital, Xi'an, 710068, China. Electronic address: fgpeter1982@126.com. ; Jiao Yu:1.Department of Radiation Oncology, Shaanxi Provincial People's Hospital, Xi'an, 710068, China. ; Bo Liu:1.Department of Ultrasound Diagnosis, Shaanxi Provincial People's Hospital, Xi'an, 710068, China. ;
期刊:CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway
DOI:10.1016/j.bbrc.2022.08.036
影响因子 :3.3
引用产品: LS180 细胞 , SW480 [SW-480] 细胞 , HT-29 细胞 , HCT 116 细胞 , DLD-1 细胞
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Circ_KIAA1199 inhibits MSI1 degradation by targeting miR-34c-5p to drive the malignant cell behaviors and tumor growth of colorectal cancer (2001-02-20)
作者:Yanbo Zhang:1.Department of General Surgery, Liaocheng People's Hospital, Liaocheng City, Shandong Province, China. ; Hailong Yu: Zhen Guo:
期刊:Circ_KIAA1199 inhibits MSI1 degradation by targeting miR-34c-5p to drive the malignant cell behaviors and tumor growth of colorectal cancer
DOI:10.1097/CAD.0000000000001164
影响因子 :2.3
引用产品: HCT 116 细胞 , DLD-1 细胞
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Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress-Mediated Apoptosis in Colon Cancer Cells (2005-01-20)
作者:Junyan Qu:1.School of Life Sciences, Chongqing University, Chongqing 401331, China. ; Cheng Zeng:1.School of Life Sciences, Chongqing University, Chongqing 401331, China. ; Tingting Zou:1.School of Life Sciences, Chongqing University, Chongqing 401331, China. ; Xu Chen:1.School of Life Sciences, Chongqing University, Chongqing 401331, China. ; Xiaolong Yang:1.The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. ; Zhenghong Lin:1.School of Life Sciences, Chongqing University, Chongqing 401331, China. ;
期刊:Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress-Mediated Apoptosis in Colon Cancer Cells
影响因子 :5.6
引用产品: HCT 116 细胞 , DLD-1 细胞
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Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal cancer organoids (2008-01-20)
作者:Lisi Zeng:1.Institute of Oncology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, China. ; Quanxing Liao:1.Department of Abdominal Surgery, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, China. ; Quanxing Zhao:1.Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China. ; 2.Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen 518055, China. ; Shengwei Jiang:1.Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China. ; 2.Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen 518055, China. ; 3.Shenzhen Key Laboratory of Gene and Antibody Therapy, Tsinghua University, Shenzhen 518055, China. ; Xianzi Yang:1.Department of Medical Oncology, Affiliated Cancer Hospital and Institute of Guangzhou Me
期刊:Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal cancer organoids
DOI:10.20892/j.issn.2095-3941.2020.0566
影响因子 :5.5
引用产品: SW620 细胞 , SW480 [SW-480] 细胞 , DLD-1 细胞 , COLO 205 细胞
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Cullin-4B promotes cell proliferation and invasion through inactivation of p53 signaling pathway in colorectal cancer (2006-01-20)
作者:Min Zhong:1.Department of Oncology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. ; Ling Zhou:1.Department of Oncology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. ; Jianping Zou:1.Department of Oncology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. ; Yan He:1.Department of Oncology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. ; Ziling Fang:1.Department of Oncology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. Electronic address: zfang916@126.com. ; Xiaojun Xiang:1.Department of Oncology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. Electronic address: xjxiang_nc@ncu.edu.cn. ;
期刊:Cullin-4B promotes cell proliferation and invasion through inactivation of p53 signaling pathway in colorectal cancer
影响因子 :2.8
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The combination of lactoferrin and linolenic acid inhibits colorectal tumor growth through activating AMPK/JNK-related apoptosis pathway (2005-01-20)
作者:Qianqian Yao:1.Key Laboratory of Quality & Safety Control for Milk and Dairy Products of Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China. ; 2.Laboratory of Quality and Safety Risk Assessment for Dairy Products of Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China. ; 3.State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China. ; Huiying Li:1.Key Laboratory of Quality & Safety Control for Milk and Dairy Products of Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China. ; 2.Laboratory of Quality and Safety Risk Assessment for Dairy Products of Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China. ; 3.State Key
期刊:The combination of lactoferrin and linolenic acid inhibits colorectal tumor growth through activating AMPK/JNK-related apoptosis pathway
影响因子 :2.7
引用产品: Hep G2 细胞 , AGS 细胞 , HCT 116 细胞 , DLD-1 细胞 , HT-29 细胞
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Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis (2005-00-20)
作者:Le Yu:1.School of Life Sciences, Chongqing University, 401331, Chongqing, China. ; Ling Dong:1.School of Life Sciences, Chongqing University, 401331, Chongqing, China. ; Hui Li:1.School of Life Sciences, Chongqing University, 401331, Chongqing, China. ; Zhaojian Liu:1.Department of Cell Biology, Shandong University School of Medicine, 250012, Jinan, China. ; Zhong Luo:1.School of Life Sciences, Chongqing University, 401331, Chongqing, China. ; Guangjie Duan:1.Department of Pulmonology, Southwest Hospital, Third Military Medical University, 400038, Chongqing, China. ; Xiaotian Dai:1.Department of Pulmonology, Southwest Hospital, Third Military Medical University, 400038, Chongqing, China. daixt1973@163.com. ; Zhenghong Lin:1.School of Life Sciences, Chongqing University, 401331, Chongqing, China. zhenghonglin@cqu.edu.cn. ;
期刊:Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis
影响因子 :8.0
引用产品: 293T [HEK-293T] 细胞 , HCT 116 细胞 , DLD-1 细胞
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miR-145-5p restrained cell growth, invasion, migration and tumorigenesis via modulating RHBDD1 in colorectal cancer via the EGFR-associated signaling pathway (2011-09-20)
作者:Ying Niu:1.Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China. ; Jinping Zhang:1.Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China. ; Yalin Tong:1.Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China. ; Jiansheng Li:1.Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China. ; Bingrong Liu:1.Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China. Electronic address: bingrongcn@163.com. ;
期刊:miR-145-5p restrained cell growth, invasion, migration and tumorigenesis via modulating RHBDD1 in colorectal cancer via the EGFR-associated signaling pathway
DOI:10.1016/j.biocel.2019.105641
影响因子 :4.0
引用产品: Caco-2 细胞 , DLD-1 细胞 , LoVo 细胞 , SW480 [SW-480] 细胞 , T84 细胞
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