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产品概述
| 名称 | AML12 (小鼠正常肝细胞) (STR鉴定正确) |
| 别称 | AML-12; AML 12; Alpha Mouse Liver 12 |
| 种属 | 小鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | The AML12 (alpha mouse liver 12) cell line was established from hepatocytes from a mouse (CD1 strain, line MT42) transgenic for human TGF alpha. |
| 年龄（性别） | 雄性；3月龄 |
| 组织来源 | 肝脏 |
| 细胞类型 | 自发永生化细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~37 hours |
| 致瘤性 | NO |
| 基因表达情况 | albumin; human transforming growth factor alpha (TGF alpha); mouse TGF alpha. |
| 保藏机构 | ATCC; CRL-2254 BCRC; 60326 BCRJ; 0354 |
STR鉴定
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STR位点信息
18-3 21 6-7 12 5-5 14,15 X-1 26 1-2 13 7-1 29 8-1 14,15 1-1 11 19-2 13 15-3 21.3 12-1 19 6-4 15.3 4-2 20.3 3-2 12 2-1 9 13-1 15.1,15.2
11-2 18,19 17-2 14,15 -
STR鉴定图
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参考文献
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Targeted delivery of polymeric NO-donor micelles to hepatic stellate cells for restoration of liver function and inhibition of hepatic fibrosis (2025-01-17)
期刊：JOURNAL OF CONTROLLED RELEASE
DOI：10.1016/j.jconrel.2025.01.036
影响因子 ：10.5
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1-phenyl-3-methyl-5-pyrazolone activates the AMPK pathway to alleviate western-diet induced metabolic dysfunction-associated steatohepatitis in mice (2025-01-04)
期刊：CLINICAL NUTRITION
DOI：10.1016/j.clnu.2024.12.033
影响因子 ：6.6
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Betaine-homocysteine methyltransferase attenuates liver ischemia–reperfusion injury by targeting TAK1 (2025-01-24)
期刊：FASEB JOURNAL
影响因子 ：4.4
引用产品： AML12 细胞 , 293T [HEK-293T] 细胞 , AML12细胞专用培养基
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Inotodiol induces hepatocellular carcinoma apoptosis by activation of MAPK/ERK pathway (2025-01-29)
期刊：PLoS One
DOI：10.1371/journal.pone.0318450
影响因子 ：2.9
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Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation (2024-09-24)
期刊：IMMUNITY
DOI：10.1016/j.immuni.2024.08.015
影响因子 ：25.5
引用产品： AML12 细胞 , RAW 264.7 细胞
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Self-Sulfhydrated, Nitro-Fixed Albumin Nanoparticles as a Potent Therapeutic Agent for the Treatment of Acute Liver Injury (2024-07-23)
期刊：ACS Nano
影响因子 ：15.8
引用产品： AML12 细胞
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Lung-Targeted Lipid Nanoparticle-Delivered siUSP33 Attenuates SARS-CoV-2 Replication and Virulence by Promoting Envelope Degradation (2024-09-20)
期刊：Advanced Science
影响因子 ：14.3
引用产品： LLC [LL/2; LLC1] 细胞 , AML12 细胞
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Sirtuin 5-Mediated Desuccinylation of ALDH2 Alleviates Mitochondrial Oxidative Stress Following Acetaminophen-Induced Acute Liver Injury (2024-08-19)
期刊：Advanced Science
影响因子 ：14.3
引用产品： AML12 细胞
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Hepatic Steatosis Aggravates Vascular Calcification via Extracellular Vesicle-Mediated Osteochondrogenic Switch of Vascular Smooth Muscle Cells (2024-12-16)
期刊：Advanced Science
影响因子 ：14.3
引用产品： AML12 细胞
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SNRK modulates mTOR-autophagy pathway for liver lipid homeostasis in MAFLD (2024-11-08)
期刊：MOLECULAR THERAPY
DOI：10.1016/j.ymthe.2024.11.016
影响因子 ：12.1
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Multivalent supramolecular fluorescent probes for accurate disease imaging (2024-10-18)
期刊：Science Advances
影响因子 ：11.7
引用产品： RAW 264.7 细胞 , LX-2 细胞 , CT26.WT 细胞 , HK-2 细胞 , AML12 细胞
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A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy (2024-01-09)
期刊：CARBOHYDRATE POLYMERS
DOI：10.1016/j.carbpol.2024.121795
影响因子 ：11.2
引用产品： 4T1 细胞 , HL-1 细胞 , 大鼠小肠隐窝上皮细胞 , AML12 细胞 , MDA-MB-231/GFP 细胞
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Acute exposure to polystyrene nanoparticles promotes liver injury by inducing mitochondrial ROS-dependent necroptosis and augmenting macrophage-hepatocyte crosstalk (2024-04-12)
期刊：Particle and Fibre Toxicology
DOI：10.1186/s12989-024-00578-6
影响因子 ：10.0
引用产品： J774A.1 细胞 , THP-1 细胞 , AML12 细胞
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Histidine-rich glycoprotein modulates neutrophils and thrombolysis-associated hemorrhagic transformation (2024-08-15)
期刊：EMBO Molecular Medicine
DOI：10.1038/s44321-024-00117-y
影响因子 ：9.0
引用产品： RPMI-1640 培养基 , AML12 细胞
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Target-Engineered Liposomes Decorated with Nanozymes Alleviate Liver Fibrosis by Remodeling the Liver Microenvironment (2024-11-12)
期刊：ACS Applied Materials & Interfaces
影响因子 ：8.3
引用产品： RAW 264.7 细胞 , HSC-T6 细胞 , AML12 细胞
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Zearalenone induces liver injury in mice through ferroptosis pathway (2024-08-30)
期刊：SCIENCE OF THE TOTAL ENVIRONMENT
DOI：10.1016/j.scitotenv.2024.175875
影响因子 ：8.2
引用产品： AML12 细胞
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Bruceine A alleviates alcoholic liver disease by inhibiting AIM2 inflammasome activation via activating FXR (2024-05-07)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155693
影响因子 ：7.9
引用产品： 胰岛素-转铁蛋白-硒添加剂（ITS-G），100× , AML12 细胞 , 特级胎牛血清
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Mitochondrial HKDC1 suppresses oxidative stress and apoptosis by regulating mitochondrial function in goose fatty liver (2024-11-02)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.137222
影响因子 ：7.7
引用产品： AML12 细胞
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Inhibition of PTPRE suppresses tumor progression and improves sorafenib response in hepatocellular carcinoma (2024-03-08)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.116366
影响因子 ：7.5
引用产品： THLE-3 细胞 , AML12 细胞
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Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway (2024-01-09)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.116133
影响因子 ：7.5
引用产品： AML12 细胞
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Dendrobium officinale regulate lipid metabolism in diabetic mouse liver via PPAR-RXR signaling pathway: Evidence from an integrated multi-omics analysis (2024-03-08)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.116395
影响因子 ：7.5
引用产品： AML12 细胞
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Amphiphilic Rhodamine Fluorescent Probes Combined with Basal Imaging for Fine Structures of the Cell Membrane (2024-04-25)
期刊：ANALYTICAL CHEMISTRY
DOI：10.1021/acs.analchem.4c00946
影响因子 ：7.4
引用产品： AML12细胞专用培养基 , HT-1080 [HT1080]细胞专用培养基 , AML12 细胞 , A549 [A-549]细胞专用培养基
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Sulfonated albumin from hepatocytes accelerates liver fibrosis in nonalcoholic fatty liver disease through endoplasmic reticulum stress (2024-12-30)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.12.055
影响因子 ：7.1
引用产品： AML12 细胞 , Hep G2 细胞 , LX-2 细胞 , 293T [HEK-293T] 细胞
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Insulin-like growth factor-binding protein7 exacerbates inflammatory response and lipid metabolism imbalance in alcohol-associated liver disease (2024-09-17)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.09.006
影响因子 ：7.1
引用产品： AML12 细胞
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SGLT2 inhibitors ameliorate NAFLD in mice via downregulating PFKFB3, suppressing glycolysis and modulating macrophage polarization (2024-09-18)
期刊：ACTA PHARMACOLOGICA SINICA
DOI：10.1038/s41401-024-01389-3
影响因子 ：6.9
引用产品： RAW 264.7 细胞 , AML12 细胞
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Multi-time point transcriptomics and metabolomics reveal key transcription and metabolic features of hepatic ischemia-reperfusion injury in mice (2024-11-17)
期刊：Genes & Diseases
DOI：10.1016/j.gendis.2024.101465
影响因子 ：6.9
引用产品： 胰岛素-转铁蛋白-硒添加剂（ITS-G），100× , AML12 细胞 , 特级胎牛血清
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Exposure to polystyrene nanoplastics induces hepatotoxicity involving NRF2-NLRP3 signaling pathway in mice (2024-05-09)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116439
影响因子 ：6.8
引用产品： AML12 细胞
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A Novel Triptolide Nano-Liposome with Mitochondrial Targeting for Treatment of Hepatocellular Carcinoma (2024-12-03)
期刊：International Journal of Nanomedicine
影响因子 ：6.6
引用产品： HuH-7 细胞 , AML12 细胞 , 磷酸盐缓冲液（PBS） 1× , 青霉素-链霉素溶液（双抗），100× , 0.25%胰蛋白酶溶液（含EDTA，溶于PBS） , DMEM高糖 培养基
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FXR overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in alcoholic liver disease (2024-01-06)
期刊：Hepatology International
DOI：10.1007/s12072-023-10621-x
影响因子 ：6.6
引用产品： AML12 细胞
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Tangerine Peel-Derived Exosome-Like Nanovesicles Alleviate Hepatic Steatosis Induced by Type 2 Diabetes: Evidenced by Regulating Lipid Metabolism and Intestinal Microflora (2024-09-29)
期刊：International Journal of Nanomedicine
影响因子 ：6.6
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Pentagalloylglucose alleviates acetaminophen-induced acute liver injury by modulating inflammation via cGAS-STING pathway (2024-09-27)
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-024-00924-6
影响因子 ：6.0
引用产品： THP-1 细胞 , 293 [HEK-293] 细胞 , 293T [HEK-293T] 细胞 , AML12 细胞
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Sesamin ameliorates nonalcoholic hepatic steatosis by inhibiting CD36-mediated hepatocyte lipid accumulation in vitro and in vivo (2024-04-26)
期刊：BIOCHEMICAL PHARMACOLOGY
影响因子 ：5.8
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Identification and validation of cuproptosis-related genes in acetaminophen-induced liver injury using bioinformatics analysis and machine learning (2024-06-27)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1371446
影响因子 ：5.7
引用产品： AML12细胞专用培养基 , AML12 细胞
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Identification of potential pathogenic hepatic super-enhancers regulatory network in high-fat diet induced hyperlipidemia (2024-01-17)
期刊：JOURNAL OF NUTRITIONAL BIOCHEMISTRY
DOI：10.1016/j.jnutbio.2024.109584
影响因子 ：5.6
引用产品： AML12 细胞 , AML-12细胞专用培养基
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Qizhu Anticancer Prescription enhances immunosurveillance of liver cancer cells by regulating p21-dependent secretory phenotypes (2024-05-31)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： 特级胎牛血清 , AML12 细胞 , AML12细胞专用培养基
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GRK2 mediates cisplatin-induced acute liver injury via the modulation of NOX4 (2024-11-15)
期刊：CELL BIOLOGY AND TOXICOLOGY
DOI：10.1007/s10565-024-09940-y
影响因子 ：5.3
引用产品： AML12 细胞
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Triptolide induces hepatotoxicity by promoting ferroptosis through Nrf2 degradation (2024-11-06)
期刊：CELL BIOLOGY AND TOXICOLOGY
DOI：10.1007/s10565-024-09930-0
影响因子 ：5.3
引用产品： AML12 细胞
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Digoxigenin activates autophagy in hepatocellular carcinoma cells by regulating the PI3K/AKT/mTOR pathway (2024-12-18)
期刊：Cancer Cell International
DOI：10.1186/s12935-024-03602-z
影响因子 ：5.3
引用产品： AML12 细胞 , Hep G2 细胞 , AML12细胞专用培养基
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Identification and validation of cuproptosis-related molecular clusters in non-alcoholic fatty liver disease (2024-01-03)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：5.3
引用产品： AML12 细胞
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10-Hydroxy-2-decenoic acid attenuates nonalcoholic fatty liver disease by activating AMPK-α signaling pathway (2024-11-23)
期刊：BIOCHEMICAL PHARMACOLOGY
影响因子 ：5.3
引用产品： AML12 细胞
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Adenosine kinase protects against acetaminophen-induced acute liver injury by activating autophagy in hepatocytes (2024-07-27)
期刊：CELL BIOLOGY AND TOXICOLOGY
DOI：10.1007/s10565-024-09906-0
影响因子 ：5.3
引用产品： AML12 细胞
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Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury (2024-05-23)
期刊：Communications Biology
DOI：10.1038/s42003-024-06243-0
影响因子 ：5.2
引用产品： AML12 细胞
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METTL3 Modulates TXNIP Expression to Affect the Activation of NLRP3 Inflammasome in Hepatic Cells Under Oxygen–Glucose Deprivation/Reperfusion Injury (2024-01-18)
期刊：INFLAMMATION
DOI：10.1007/s10753-023-01958-4
影响因子 ：5.1
引用产品： AML12 细胞 , DMEM/F12 培养基
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MRG15 aggravates sepsis-related liver injury by promoting PCSK9 synthesis and secretion (2024-08-10)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112898
影响因子 ：4.8
引用产品： AML12 细胞 , RAW 264.7 细胞 , 293T [HEK-293T] 细胞
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Diammonium glycyrrhizinate ameliorates alcohol-induced liver injury by reducing oxidative stress, steatosis, and inflammation (2024-10-18)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113374
影响因子 ：4.8
引用产品： AML12 细胞 , AML12细胞专用培养基
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The regulation of GSH/GPX4-mediated lipid accumulation confirms that schisandra polysaccharides should be valued equally as lignans (2024-06-22)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： AML12细胞专用培养基 , AML12 细胞
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Inhibition of mitochondrial ROS-mediated necroptosis by Dendrobium nobile Lindl. alkaloids in carbon tetrachloride induced acute liver injury (2024-04-26)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： AML12 细胞
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Tanshinone IIA, a Component of Salvia miltiorrhiza Bunge, Attenuated Sepsis-induced Liver Injury via the SIRT1/Sestrin2/HO-1 Signaling Pathway (2024-11-29)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： AML12 细胞
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Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway (2024-03-30)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： AML12 细胞
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Nepetoidin B Alleviates Liver Ischemia/Reperfusion Injury via Regulating MKP5 and JNK/P38 Pathway (2024-06-16)
期刊：Drug Design Development and Therapy
影响因子 ：4.7
引用产品： DMEM无糖 培养基 , AML12 细胞
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6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway (2024-04-02)
期刊：Scientific Reports
DOI：10.1038/s41598-024-58392-1
影响因子 ：4.6
引用产品： Ham's F-12K无糖 培养基 , DMEM/F12 培养基 , AML12 细胞
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Exploring the mechanism and phytochemicals in Psoraleae Fructus-induced hepatotoxicity based on RNA-seq, in vitro screening and molecular docking (2024-01-19)
期刊：Scientific Reports
DOI：10.1038/s41598-023-50454-0
影响因子 ：4.6
引用产品： AML12 细胞
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Cordycepin alleviates diabetes mellitus-associated hepatic fibrosis by inhibiting SOX9-mediated Wnt/β-catenin signal axis (2024-09-06)
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2024.107812
影响因子 ：4.5
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JuA alleviates liver ischemia-reperfusion injury by activating AKT/NRF2/HO-1 pathways (2024-09-03)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2024.167496
影响因子 ：4.2
引用产品： AML12 细胞 , DMEM/F12（不含L-谷氨酰胺） 培养基
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Metformin improves nonalcoholic fatty liver disease in db/db mice by inhibiting ferroptosis (2024-01-18)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176341
影响因子 ：4.2
引用产品： AML12 细胞 , 胰岛素-转铁蛋白-硒添加剂（ITS-G），100×
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BNIP3 in hypoxia-induced mitophagy: novel insights and promising target for non-alcoholic fatty liver disease (2024-01-11)
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2024.106517
影响因子 ：4.0
引用产品： AML12 细胞
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Role of USF1 in activating CYBA transcription and influencing NADPH-ROS-mediated oxidative stress and lipid accumulation in non-alcoholic fatty liver disease (2024-11-20)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
DOI：10.1016/j.bbalip.2024.159581
影响因子 ：3.9
引用产品： AML12 细胞
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Kurarinol restrains non-alcoholic fatty liver disease-associated hepatocellular carcinoma (HCC) progression by suppressing EGFR signaling (2024-08-22)
期刊：Journal of Functional Foods
影响因子 ：3.8
引用产品： AML12 细胞
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Effect of Rab18 on liver injury and lipid accumulation by regulating perilipin 2 and peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease (2024-07-18)
期刊：JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
影响因子 ：3.7
引用产品： DMEM/F12 培养基 , AML12 细胞
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Knockdown of the Clock gene in the liver aggravates MASLD in mice via inhibiting lipophagy (2024-09-14)
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-024-05109-7
影响因子 ：3.5
引用产品： AML12 细胞
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Identification and validation of cuproptosis-related genes for diagnosis and therapy in nonalcoholic fatty liver disease (2024-03-21)
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-024-04957-7
影响因子 ：3.5
引用产品： AML12 细胞 , AML12细胞专用培养基
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Sevoflurane blocks KLF5-mediated transcriptional activation of ITGB2 to inhibit macrophage infiltration in hepatic ischemia/reperfusion injury (2024-05-14)
期刊：JOURNAL OF GENE MEDICINE
DOI：10.1002/jgm.3692
影响因子 ：3.5
引用产品： DMEM/F12 培养基 , DMEM低糖完全培养基（含10% FBS） , AML12 细胞 , AML12细胞专用培养基
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Immune Infiltration Analysis Based on Pyroptosis-related Gene in Metabolic dysfunction-associated fatty liver disease (2024-07-09)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e34348
影响因子 ：3.4
引用产品： AML12 细胞
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Exercise training alleviates cholesterol and lipid accumulation in mice with non-alcoholic steatohepatitis: reduction of KMT2D-mediated histone methylation of IDI1 (2024-09-25)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2024.114265
影响因子 ：3.3
引用产品： AML12细胞专用培养基 , AML12 细胞
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Inhibition of ROS/caspase-3/GSDME-mediated pyroptosis alleviates high glucose-induced injury in AML-12 cells (2024-05-08)
期刊：TOXICOLOGY IN VITRO
影响因子 ：3.2
引用产品： 胰岛素-转铁蛋白-硒添加剂（ITS-G），100× , DMEM/F12 培养基 , AML12 细胞
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The augment effects of magnesium hydride on the lipid lowering effect of atorvastatin: an in vivo and in vitro investigation (2024-03-28)
期刊：Medical Gas Research
DOI：10.4103/mgr.MEDGASRES-D-23-00047
影响因子 ：2.9
引用产品： AML12 细胞
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Ghrelin alleviates inflammation and pyroptosis by inhibiting TNF-α /caspase-8/caspase-3/ GSDME signalling pathways in an in vitro model of high glucose induced liver injury (2024-12-10)
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2024.102672
影响因子 ：2.7
引用产品： DMEM/F12无糖 培养基 , AML12 细胞
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Dendrobium nobile Lindl. alkaloids protect CCl4-induced acute liver injury via upregulating LAMP1 expression and activating autophagy flux (2024-11-15)
期刊：Journal of Natural Medicines
DOI：10.1007/s11418-024-01852-9
影响因子 ：2.5
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Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning (2024-01-15)
期刊：American Journal of Translational Research
DOI：PMID:38322557
影响因子 ：2.2
引用产品： AML12 细胞
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tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis (2023-04-03)
期刊：Signal Transduction and Targeted Therapy
DOI：10.1038/s41392-023-01351-5
影响因子 ：39.3
引用产品： HL-7702 [L-02; LO2] 细胞 , AML12 细胞
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m6A modification-tuned sphingolipid metabolism regulates postnatal liver development in male mice (2023-05-15)
期刊：Nature Metabolism
DOI：10.1038/s42255-023-00808-9
影响因子 ：20.8
引用产品： AML12 细胞
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Cullin-associated and neddylation-dissociated protein 1 (CAND1) alleviates NAFLD by reducing ubiquitinated degradation of ACAA2 (2023-08-01)
期刊：Nature Communications
DOI：10.1038/s41467-023-40327-5
影响因子 ：16.6
引用产品： AML12 细胞 , Hep G2 细胞 , AML-12细胞专用培养基
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Bioinspired porous three-coordinated single-atom Fe nanozyme with oxidase-like activity for tumor visual identification via glutathione (2023-11-06)
期刊：Nature Communications
DOI：10.1038/s41467-023-42889-w
影响因子 ：16.6
引用产品： Hepa 1-6 细胞 , AML12 细胞
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O-GlcNAcylation of Raptor transduces glucose signals to mTORC1 (2023-08-03)
期刊：MOLECULAR CELL
DOI：10.1016/j.molcel.2023.07.011
影响因子 ：16.0
引用产品： AML-12细胞专用培养基 , AML12 细胞
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Synergistic D-Amino Acids Based Antimicrobial Cocktails Formulated via High-Throughput Screening and Machine Learning (2023-12-21)
期刊：Advanced Science
影响因子 ：15.1
引用产品： BEAS-2B细胞专用培养基 , BEAS-2B 细胞 , MC3T3-E1 Subclone 24 (新引进) 细胞 , MEM（含NEAA） 培养基 , AML12细胞专用培养基 , MEM完全培养基（含NEAA、10% FBS） , AML12 细胞 , MC3T3-E1 Subclone 24细胞专用培养基（新引进）
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Inhibition of free heme-catalyzed Fenton-like reaction prevents non-alcoholic fatty liver disease by hepatocyte-targeted hydrogen delivery (2023-07-01)
期刊：BIOMATERIALS
DOI：10.1016/j.biomaterials.2023.122230
影响因子 ：14.0
引用产品： AML12 细胞
-
Alcoholic Setdb1 suppression promotes hepatosteatosis in mice by strengthening Plin2 (2023-07-06)
期刊：METABOLISM-CLINICAL AND EXPERIMENTAL
DOI：10.1016/j.metabol.2023.155656
影响因子 ：9.8
引用产品： AML12 细胞
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DBF4 Dependent Kinase Inhibition Suppresses Hepatocellular Carcinoma Progression and Potentiates Anti-Programmed Cell Death-1 Therapy (2023-07-03)
期刊：International Journal of Biological Sciences
影响因子 ：9.2
引用产品： AML12 细胞
-
Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway in vivo and in vitro (2023-04-03)
期刊：Frontiers of Medicine
影响因子 ：8.1
引用产品： AML12 细胞
-
Surface Engineering of HEK293 Cell-Derived Extracellular Vesicles for Improved Pharmacokinetic Profile and Targeted Delivery of IL-12 for the Treatment of Hepatocellular Carcinoma (2023-01-12)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： AML12 细胞 , MRC-5 细胞 , 293T [HEK-293T] 细胞 , RAW 264.7 细胞 , Hep G2 细胞
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Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1 (2023-01-07)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-022-03862-1
影响因子 ：7.4
引用产品： AML12 细胞 , McCoy's 5A 培养基
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ETNPPL impairs autophagy through regulation of the ARG2-ROS signaling axis, contributing to palmitic acid-induced hepatic insulin resistance (2023-02-24)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2023.02.017
影响因子 ：7.4
引用产品： Hep G2 细胞 , AML12 细胞 , 293T [HEK-293T] 细胞 , 293A 细胞
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Angelica sinensis polysaccharide ameliorates nonalcoholic fatty liver disease via restoring estrogen-related receptor α expression in liver (2023-08-10)
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.7982
影响因子 ：7.2
引用产品： AML12 细胞
-
Sappanone A Alleviates the Severity of Carbon Tetrachloride-Induced Liver Fibrosis in Mice (2023-09-04)
期刊：Antioxidants
影响因子 ：7.0
引用产品： AML12 细胞 , RAW 264.7 细胞 , LX-2 细胞
-
Adipose-Derived Mesenchymal Stem Cells Inhibit JNK-Mediated Mitochondrial Retrograde Pathway to Alleviate Acetaminophen-Induced Liver Injury (2023-01-09)
期刊：Antioxidants
影响因子 ：7.0
引用产品： AML12 细胞
-
Environmental toxin chlorpyrifos induces liver injury by activating P53-mediated ferroptosis via GSDMD-mtROS (2023-04-24)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.114938
影响因子 ：6.8
引用产品： AML12 细胞
-
Perfluorooctane sulfonate (PFOS), a novel environmental pollutant, induces liver injury in mice by activating hepatocyte ferroptosis (2023-10-27)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115625
影响因子 ：6.8
引用产品： AML12 细胞 , AML-12细胞专用培养基
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Cannabidiol alleviates perfluorooctane sulfonate-induced macrophage extracellular trap mediate inflammation and fibrosis in mice liver (2023-08-15)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115374
影响因子 ：6.8
引用产品： RAW 264.7 细胞 , AML12 细胞 , LX-2 细胞
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Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease (2023-10-31)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2023.166930
影响因子 ：6.2
引用产品： AML12 细胞 , 特级胎牛血清 , 胰岛素-转铁蛋白-硒添加剂 (ITS-G)，100×
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Identification of antioxidant peptides after digestion and absorption of isinglass by serum peptidomics and cellular antioxidant activity analysis (2023-02-10)
期刊：Food & Function
影响因子 ：6.1
引用产品： AML12 细胞 , DMEM/F12 培养基
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Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions (2023-11-14)
期刊：iScience
DOI：10.1016/j.isci.2023.108446
影响因子 ：5.8
引用产品： AML12细胞专用培养基 , AML12 细胞
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Self-assembled FGF21 nanoparticles alleviate drug-induced acute liver injury (2023-01-10)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2022.1084799
影响因子 ：5.6
引用产品： AML12 细胞
-
Trans-anethole pretreatment ameliorates hepatic ischemia–reperfusion injury via regulation of soluble epoxide hydrolase (2023-09-08)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110809
影响因子 ：5.6
引用产品： AML12 细胞 , AML-12细胞专用培养基
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Hepatocyte-derived exosomes deliver H2AFJ to hepatic stellate cells and promote liver fibrosis via the MAPK/STMN1 axis activation (2023-01-04)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2022.109605
影响因子 ：5.6
引用产品： AML12 细胞 , 青霉素-链霉素溶液 (双抗)，100× , DMEM/F12 培养基 , 小鼠肝星状细胞 , 小鼠肝星状细胞完全培养基
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Use of a ferroptosis-related gene signature to construct diagnostic and prognostic models for assessing immune infiltration in metabolic dysfunction-associated fatty liver disease (2023-10-19)
期刊：Frontiers in Cell and Developmental Biology
DOI：10.3389/fcell.2023.1199846
影响因子 ：5.5
引用产品： AML12 细胞 , DMEM高糖 培养基
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Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death (2023-11-26)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
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Pectolinarigenin attenuates hepatic ischemia/reperfusion injury via activation of the PI3K/AKT/Nrf2 signaling pathway (2023-10-12)
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 ：5.1
引用产品： AML12 细胞
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Design, synthesis and triglyceride-lowering activity of tricyclic matrine derivatives for the intervention of non-alcoholic fatty liver disease (2023-10-18)
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2023.106925
影响因子 ：5.1
引用产品： AML12 细胞
-
Adelmidrol ameliorates liver ischemia-reperfusion injury through activating Nrf2 signaling pathway (2023-12-17)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2023.176224
影响因子 ：5.0
引用产品： AML12 细胞 , DMEM/F12 培养基
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Skimmianine attenuates liver ischemia/reperfusion injury by regulating PI3K–AKT signaling pathway-mediated inflammation, apoptosis and oxidative stress (2023-10-25)
期刊：Scientific Reports
DOI：10.1038/s41598-023-45354-2
影响因子 ：4.6
引用产品： DMEM/F12 培养基 , AML12 细胞
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Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis (2023-07-08)
期刊：Lipids in Health and Disease
DOI：10.1186/s12944-023-01855-7
影响因子 ：4.5
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Oral administration of kynurenic acid delays the onset of type 2 diabetes in Goto-Kakizaki rats (2023-06-27)
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e17733
影响因子 ：4.0
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Suppression of SIRT1/FXR signaling pathway contributes to oleanolic acid-induced liver injury (2023-04-05)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2023.116509
影响因子 ：3.8
引用产品： AML12 细胞
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Low?dose ionizing radiation attenuates high glucose?induced hepatic apoptosis and immune factor release via modulation of a miR?155?SOCS1 axis (2023-07-24)
期刊：Molecular Medicine Reports
影响因子 ：3.4
-
AMP-activated protein kinase-farnesoid X receptor?pathway contributes to oleanolic acid-induced liver injury (2023-02-27)
期刊：JOURNAL OF APPLIED TOXICOLOGY
DOI：10.1002/jat.4456
影响因子 ：3.3
引用产品： AML12 细胞
-
Upregulated microRNA-450b-5p represses the development of acute liver failure via modulation of liver function, inflammatory response, and hepatocyte apoptosis (2023-02-24)
期刊：Immunity Inflammation and Disease
DOI：10.1002/iid3.767
影响因子 ：3.2
引用产品： AML12 细胞
-
HMG-CoA reductase inhibitor from the endophytic fungus Colletotrichum Capsici (2023-11-28)
期刊：NATURAL PRODUCT RESEARCH
DOI：10.1080/14786419.2023.2289085
影响因子 ：2.2
引用产品： AML12 细胞 , DMEM高糖 培养基
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In vitro and in?vivo metabolic profiling of PD105, a PI3Kδ inhibitor, using UHPLC-Q-Exactive plus-MS (2023-03-13)
期刊：XENOBIOTICA
DOI：10.1080/00498254.2023.2188070
影响因子 ：1.8
引用产品： AML12 细胞
-
Multicomponent microspheres with spatiotemporal drug release for post-surgical liver cancer treatment and liver regeneration (2022-12-01)
期刊：CHEMICAL ENGINEERING JOURNAL
影响因子 ：16.7
引用产品： AML12 细胞
-
Dietary Lactobacillus reuteri prevent from inflammation mediated apoptosis of liver via improving intestinal microbiota and bile acid metabolism (2022-10-18)
期刊：FOOD CHEMISTRY
DOI：10.1016/j.foodchem.2022.134643
影响因子 ：9.2
引用产品： AML12 细胞
-
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy (2022-10-18)
期刊：LIVER INTERNATIONAL
影响因子 ：8.8
引用产品： AML12 细胞 , AML-12细胞专用培养基
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FNDC3B protects steatosis and ferroptosis via the AMPK pathway in alcoholic fatty liver disease (2022-11-03)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2022.10.322
影响因子 ：8.1
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Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate experimental non-alcoholic steatohepatitis via Nrf2/NQO-1 pathway (2022-09-10)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2022.08.037
影响因子 ：8.1
引用产品： DMEM/F12 培养基 , Hep G2 细胞 , AML12 细胞
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ADSCs-derived exosomes ameliorate hepatic fibrosis by suppressing stellate cell activation and remodeling hepatocellular glutamine synthetase-mediated glutamine and ammonia homeostasis (2022-10-04)
期刊：Stem Cell Research & Therapy
DOI：10.1186/s13287-022-03049-x
影响因子 ：8.1
引用产品： AML12 细胞 , 小鼠肝星状细胞 , 小鼠肝星状细胞完全培养基
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A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles (2022-10-20)
期刊：Journal of Tissue Engineering
影响因子 ：7.9
引用产品： AML12 细胞 , HL-7702 [L-02; LO2] 细胞
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Targeting PARK7 Improves Acetaminophen-Induced Acute Liver Injury by Orchestrating Mitochondrial Quality Control and Metabolic Reprogramming (2022-10-28)
期刊：Antioxidants
影响因子 ：7.7
引用产品： AML12 细胞
-
The Protective Effect of Sericin on AML12 Cells Exposed to Oxidative Stress Damage in a High-Glucose Environment (2022-04-05)
期刊：Antioxidants
影响因子 ：7.0
引用产品： AML12 细胞
-
Dietary Selenium Alleviated Mouse Liver Oxidative Stress and NAFLD Induced by Obesity by Regulating the KEAP1/NRF2 Pathway (2022-02-10)
期刊：Antioxidants
影响因子 ：7.0
引用产品： AML12 细胞
-
Catalpol inhibits hepatic stellate cell activation by reducing the formation and changing the contents of hepatocyte-derived extracellular vesicles (2022-12-12)
期刊：Journal of Cell Communication and Signaling
DOI：10.1007/s12079-022-00716-9
影响因子 ：5.9
引用产品： AML12 细胞
-
Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress (2022-10-17)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2022.109185
影响因子 ：5.7
引用产品： AML12 细胞 , DMEM/F12 培养基
-
Liraglutide inhibits receptor for advanced glycation end products (RAGE)/reduced form of nicotinamide-adenine dinucleotide phosphate (NAPDH) signaling to ameliorate non-alcoholic fatty liver disease (NAFLD) in vivo and vitro (2022-02-14)
期刊：Bioengineered
DOI：10.1080/21655979.2022.2036902
影响因子 ：4.9
引用产品： AML12 细胞
-
SIRT5 alleviates hepatic ischemia and reperfusion injury by diminishing oxidative stress and inflammation via elevating SOD1 and IDH2 expression (2022-08-19)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2022.113319
影响因子 ：4.2
引用产品： AML12 细胞 , AML-12细胞专用培养基
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Octreotide ameliorates hepatic ischemia-reperfusion injury through SNHG12/TAF15-mediated Sirt1 stabilization and YAP1 transcription (2022-03-18)
期刊：Toxicology And Applied Pharmacology
DOI：10.1016/j.taap.2022.115975
影响因子 ：3.8
引用产品： AML12 细胞
-
Circadian rhythm disorders elevate macrophages cytokines release and promote multiple tissues/organs dysfunction in mice (2022-03-02)
期刊：Physiol Behav
DOI：10.1016/j.physbeh.2022.113772
影响因子 ：2.9
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Basic fibroblast growth factor protects against liver ischemia-reperfusion injury via the Nrf2/Hippo signaling pathway (2022-09-08)
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2022.101921
影响因子 ：2.6
引用产品： AML12 细胞
-
Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced (2022-12-02)
期刊：Jove-Journal of Visualized Experiments
DOI：10.3791/64816
影响因子 ：1.4
引用产品： AML12 细胞
-
Overexpression of PDE4D in mouse liver is sufficient to trigger NAFLD and hypertension in a CD36-TGF-β1 pathway: therapeutic role of roflumilast (2021-11-24)
期刊：Pharmacological Research
DOI：10.1016/j.phrs.2021.106004
影响因子 ：10.3
引用产品： AML12 细胞 , AML-12细胞专用培养基
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