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产品概述
| 名称 | CT26.WT (小鼠结肠癌细胞) (STR鉴定正确) |
| 别称 | CT26WT |
| 种属 | 小鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | CT26细胞是以N-亚硝基-N-甲基氨基甲酸酯(NNMU)诱导形成的未分化结肠癌细胞株，它克隆形成的细胞株命名为CT26.WT。用包含编码典型肿瘤相关抗原(TAA)β-半乳糖苷酶(β-gal)的lacZ基因的逆转录病毒载体LXSN稳定转染CT26.WT细胞，得到致死的亚克隆CT26.CL25。即使CT26.CL25细胞表达了典型的TAA-β-半乳糖苷酶，在正常小鼠中CT26.CL25细胞和CT26.WT细胞的生长率与致死率也保持基本一致。CT26.WT细胞与CT26.CL25细胞一起可用作测试免疫治疗程序的模型，并用于研究宿主免疫反应。 |
| 年龄（性别） | 不详 |
| 组织来源 | 器官：结肠；品系：BALB/c；疾病：癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肠癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | Yes, in BALB/c mice. Mice inoculated, subcutaneously, developed lethal tumors at 80% frequency with 1×10^3 cells and at 100% with 1×10^4 cells. Pulmonary metastases developed when mice were inoculated, intravenously, with 1×10^4 cells. |
| 抗原表达情况 | H-2d |
| 保藏机构 | ATCC; CRL-2638 BCRC; 60447 |
STR鉴定
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STR位点信息
18-3 19 6-7 12 5-5 14 X-1 25,26 1-2 17,18 7-1 25.2 8-1 13 1-1 14,15 19-2 13 15-3 21.3,22.3 12-1 16,17 6-4 18,20 4-2 21.3 3-2 14 2-1 16,17 13-1 16.2,17.2,18.2
11-2 17 17-2 15,16,17 -
STR鉴定图
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参考文献
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Enhancing tumor-specific recognition of programmable synthetic bacterial consortium for precision therapy of colorectal cancer (2024-01-20)
作者：Tuoyu Zhou:1.Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, China. ; Jingyuan Wu:1.The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, China. ; Haibo Tang:1.Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, China. ; Dali Liu:1.Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL, USA. ; Byong-Hun Jeon:1.Department of Earth Resources and Environmental Engineering, Hanyang University, Seoul, Korea. ; Weilin Jin:1.Medical Frontier Innovation Research Center, The First Hospital of Lanzhou University, Lanzhou, China. ; Yiqing Wang:1.The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, China. ; Yuanzhang Zheng:1.Discovery Biology, Curia Golbal Inc, New York, NY, USA. ; Aman Khan:1.Ministry of Education Key Laboratory of
期刊：Enhancing tumor-specific recognition of programmable synthetic bacterial consortium for precision therapy of colorectal cancer
DOI：10.1038/s41522-024-00479-8
影响因子 ：9.2
引用产品： CT26.WT 细胞 , RKO 细胞 , SW480 [SW-480] 细胞
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The Impact of Atmospheric Cadmium Exposure on Colon Cancer and the Invasiveness of Intestinal Stents in the Cancerous Colon (2024-03-14)
作者：Shuai Zhang:1.Department of General Surgery, Tianjin Union Medical Center, No. 190 Jieyuan Road, Hongqiao District, Tianjin 300121, China. ; Ruikang Li:1.Tianjin Key Laboratory of Urban Transport Emission Research & State Environmental Protection Key Laboratory of Urban Ambient Air Particulate Matter Pollution Prevention and Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China. ; Jing Xu:1.Department of General Surgery, Tianjin Union Medical Center, No. 190 Jieyuan Road, Hongqiao District, Tianjin 300121, China. ; Yan Liu:1.Tianjin Key Laboratory of Urban Transport Emission Research & State Environmental Protection Key Laboratory of Urban Ambient Air Particulate Matter Pollution Prevention and Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China. ; Yanjie Zhang:1.Tianjin Youmei Environment Technology, Ltd., Tianjin 300300, China. ;
期刊：The Impact of Atmospheric Cadmium Exposure on Colon Cancer and the Invasiveness of Intestinal Stents in the Cancerous Colon
影响因子 ：4.6
引用产品： CT26.WT 细胞 , CT26.WT细胞专用培养基
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Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases (2023-06-14)
作者：Qiang Wang:1.Digestive Diseases Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University, Shenzhen, Guangdong, China. ; 2.Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital of Sun Yat-Sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, China. ; 3.Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China. ; Peng Liu:1.Digestive Diseases Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University, Shenzhen, Guangdong, China. ; 2.Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital of Sun Yat-Sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, China. ; 3.Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China. ; Yingfei Wen:1.Scientific Research Center, The Seventh Affiliated Hospital of Sun
期刊：Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases
DOI：10.1186/s12943-023-01790-2
影响因子 ：37.3
引用产品： MGC80-3 [MGC-803] 细胞 , HGC-27 细胞 , CT26.WT 细胞 , CT26.WT 细胞
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Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation (2023-07-26)
作者：Jiaqi Meng:1.State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China. ; 2.School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China. ; Yanlin Lv:1.State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China. ; Weier Bao:1.State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China. ; 2.School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China. ; Zihui Meng:1.Department of Hepatobiliary-Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, P. R. China. ; Shuang Wang:1.State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China. ; Yuanbin Wu:1.
期刊：Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation
DOI：10.1038/s41467-023-40207-y
影响因子 ：16.6
引用产品： 4T1 细胞 , CT26.WT 细胞 , LLC [LL/2; LLC1] 细胞
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Modular Hydrogel Vaccine for Programmable and Coordinate Elicitation of Cancer Immunotherapy (2023-05-24)
作者：Panpan Ji:1.Department of Digestive Surgery, Xijing Hospital, Fourth Military Medical University, Shaanxi, 710032, China. ; Wenqi Sun:1.Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Shaanxi, 710038, China. ; Siyan Zhang:1.Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Shaanxi, 710038, China. ; Yuqi Xing:1.The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Shaanxi, 710032, China. ; Chen Wang:1.Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Shaanxi, 710038, China. ; Mengying Wei:1.The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Shaanxi, 710032, China. ; Qiuyun Li:1.Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China. ; Gang Ji:1.D
期刊：Modular Hydrogel Vaccine for Programmable and Coordinate Elicitation of Cancer Immunotherapy
影响因子 ：15.1
引用产品： 4T1 细胞 , CT26.WT 细胞
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Microbubbles-assisted ultrasonication to promote tumor accumulation of therapeutics and modulation of tumor microenvironment for enhanced cancer treatments (2023-06-01)
作者：Ju Huang:1.Chongqing Key Laboratory of Ultrasound Molecular Imaging, Institute of Ultrasound Imaging, Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China. ; Liang Zhang:1.Chongqing Key Laboratory of Ultrasound Molecular Imaging, Institute of Ultrasound Imaging, Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China; Department of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400042, PR China. ; Jun Zheng:1.Chongqing Key Laboratory of Ultrasound Molecular Imaging, Institute of Ultrasound Imaging, Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China. ; Yi Lin:1.Department of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400042, PR China. ; Xiaojing Leng:1.Chongqing Key Laboratory of Ultrasound Molecular Imaging, In
期刊：Microbubbles-assisted ultrasonication to promote tumor accumulation of therapeutics and modulation of tumor microenvironment for enhanced cancer treatments
DOI：10.1016/j.biomaterials.2023.122181
影响因子 ：14.0
引用产品： CT26.WT 细胞 , 人脐静脉内皮细胞 , RPMI-1640 培养基
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Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment (2023-02-09)
作者：Jun Zheng:1.State Key Laboratory of Ultrasound in Medicine and Engineering, Institute of Ultrasound Imaging, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, People's Republic of China. ; Ju Huang:1.State Key Laboratory of Ultrasound in Medicine and Engineering, Institute of Ultrasound Imaging, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, People's Republic of China. ; Liang Zhang:1.State Key Laboratory of Ultrasound in Medicine and Engineering, Institute of Ultrasound Imaging, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, People's Republic of China. zhangliang338@cqmu.edu.cn. ; 2.Ultrasound Department, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400042, People's Republic of China. zhangliang338@cqmu.edu.cn. ; Mengna Wang:1.Department of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, People's Republic of China. ;
期刊：Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment
DOI：10.1186/s40824-023-00350-5
影响因子 ：11.3
引用产品： RAW 264.7 细胞 , CT26.WT 细胞
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Original research: Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer (2023-08-18)
作者：Yibo Quan:1.Guangzhou Digestive Disease Center, Guangzhou First People's Hospital and The Second Affiliated Hospital, South China University of Technology School of Medicine, South China University of Technology, Guangzhou, China. ; Jie He:1.Guangzhou Digestive Disease Center, Guangzhou First People's Hospital and The Second Affiliated Hospital, South China University of Technology School of Medicine, South China University of Technology, Guangzhou, China. ; 2.Center for Pancreatic Cancer Research and Department of Immunology, The South China University of Technology School of Medicine, South China University of Technology, Guangzhou, China. ; Qi Zou:1.Guangzhou Digestive Disease Center, Guangzhou First People's Hospital and The Second Affiliated Hospital, South China University of Technology School of Medicine, South China University of Technology, Guangzhou, China. ; 2.Center for Pancreatic Cancer Research and Department of Immunology, The South China University of Technology Schoo
期刊：Original research: Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer
影响因子 ：10.9
引用产品： CT26.WT 细胞
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Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner (2023-02-03)
作者：Yiru Long:1.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. ; 2.University of Chinese Academy of Sciences, Beijing, China. ; Runqiu Chen:1.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. ; 2.Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, China. ; Xiaolu Yu:1.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. ; 2.University of Chinese Academy of Sciences, Beijing, China. ; Yongliang Tong:1.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. ; 2.University of Chinese Academy of Sciences, Beijing, China. ; Xionghua Peng:1.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
期刊：Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner
DOI：10.1158/2326-6066.CIR-22-0439
影响因子 ：10.1
引用产品： Jurkat, Clone E6-1 细胞 , RKO 细胞 , CT26.WT 细胞 , B16-F10 细胞 , MC38 细胞 , 4T1 细胞 , LLC [LL/2; LLC1] 细胞 , Hepa 1-6 细胞 , YAC-1 细胞 , 293T [HEK-293T] 细胞 , AAV-293 细胞 , STR鉴定
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Aggregation-induced emission photosensitizer/bacteria biohybrids enhance Cerenkov radiation-induced photodynamic therapy by activating anti-tumor immunity for synergistic tumor treatment (2023-06-15)
作者：Ziyang Zhu:1.Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China; Key Laboratory of Biological Targeted Therapy, the Ministry of Education, Wuhan, 430022, China. ; Qingyao Liu:1.Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China; Key Laboratory of Biological Targeted Therapy, the Ministry of Education, Wuhan, 430022, China. ; Ke Zhu:1.Department of Nuclear Medicine, Zigong First People's Hospital, Zigong Academy of Medical Sciences, Zigong, 643000, China. ; Kun Wang:1.Department of Nuclear Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, China. ; Lan Lin:1.Department of Integrated Traditional Chinese and Western Medicine, Uni
期刊：Aggregation-induced emission photosensitizer/bacteria biohybrids enhance Cerenkov radiation-induced photodynamic therapy by activating anti-tumor immunity for synergistic tumor treatment
DOI：10.1016/j.actbio.2023.06.009
影响因子 ：9.7
引用产品： CT26.WT 细胞
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Smart Nanosystem-Mediated Inhibition of Mitochondrial Respiration for Enhanced Phototherapy-Induced Antitumor Immunity (2023-06-25)
作者：Yifan Zhao:1.Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, 266071, People's Republic of China. ; Bai Lv:1.Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, 266071, People's Republic of China. ; Guanghe Xue:1.Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, 266071, People's Republic of China. ; Yong Sun:1.Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, 266071, People's Republic of China. ; Jie Cao:1.Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, 266071, People's Republic of China. ;
期刊：Smart Nanosystem-Mediated Inhibition of Mitochondrial Respiration for Enhanced Phototherapy-Induced Antitumor Immunity
影响因子 ：8.0
引用产品： CT26.WT 细胞 , RPMI-1640 培养基 , 特级胎牛血清
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Dual-inhibition of lactate metabolism and Prussian blue-mediated radical generation for enhanced chemodynamic therapy and antimetastatic effect (2023-04-18)
作者：Wenting Li:1.Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China. gaishili@hrbeu.edu.cn. ; Shikai Liu:1.Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China. gaishili@hrbeu.edu.cn. ; Yangyang Zhang:1.Key Laboratory of Hepatosplenic Surgery, Ministry of Education, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, P. R. China. ; Jialing Zhou:1.Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China. gaishili@hrbeu.edu.cn. ; Rumin Li:1.Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College o
期刊：Dual-inhibition of lactate metabolism and Prussian blue-mediated radical generation for enhanced chemodynamic therapy and antimetastatic effect
影响因子 ：6.7
引用产品： RPMI-1640完全培养基 (含10%FBS） , NCTC clone 929 [L 细胞, L-929] 细胞 , CT26.WT 细胞
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Tumor-targeting engineered probiotic Escherichia coli Nissle 1917 inhibits colorectal tumorigenesis and modulates gut microbiota homeostasis in mice (2023-04-24)
作者：Haibo Tang:1.Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Lanzhou, China. ; Tuoyu Zhou:1.Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Lanzhou, China. ; Weilin Jin:1.Institute of Cancer Neuroscience, Medical Frontier Innovation Research Center, The First Hospital of Lanzhou University, The First Clinical Medical College of Lanzhou University, Lanzhou, China. ; Simin Zong:1.Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Lanzhou, China. ; Tursunay Mamtimin:1.Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Lanzhou, China. ; El-Sayed Salama:1.Department of Occupational and Environmental Health, School of Public Health, Lanzhou University, Lanzhou, China. ; Byong-Hun Jeon:1.Depart
期刊：Tumor-targeting engineered probiotic Escherichia coli Nissle 1917 inhibits colorectal tumorigenesis and modulates gut microbiota homeostasis in mice
影响因子 ：6.1
引用产品： CT26.WT 细胞
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Ansofaxine hydrochloride inhibits tumor growth and enhances Anti-TNFR2 in murine colon cancer model (2023-12-14)
作者：Qianyu Jing:1.School of Basic Medical Sciences, Zunyi Medical University, Zunyi, China. ; Quan Wan:1.School of Basic Medical Sciences, Zunyi Medical University, Zunyi, China. ; Yujie Nie:1.NHC Key Laboratory of Pulmonary Immunological Diseases, Guizhou Provincial People's Hospital, Guiyang, China. ; Junqian Luo:1.The First People's Hospital of Jinzhong, Jinzhong, China. ; Xiangyan Zhang:1.NHC Key Laboratory of Pulmonary Immunological Diseases, Guizhou Provincial People's Hospital, Guiyang, China. ; Lan Zhu:1.School of Medicine, Guizhou University, Guiyang, China. ; Huan Gui:1.School of Medicine, Guizhou University, Guiyang, China. ; Linzhao Li:1.School of Medicine, Guizhou University, Guiyang, China. ; Chenglv Wang:1.School of Medicine, Guizhou University, Guiyang, China. ; Shuanghui Chen:1.School of Medicine, Guizhou University, Guiyang, China. ; Mengjiao Wang:1.School of Medicine, Guizhou University, Guiyang, China. ; Haohua Yuan:1.School of Medicine, Guizhou University, G
期刊：Ansofaxine hydrochloride inhibits tumor growth and enhances Anti-TNFR2 in murine colon cancer model
DOI：10.3389/fphar.2023.1286061
影响因子 ：5.6
引用产品： CT26.WT 细胞 , MCA38 细胞 , 4T1 细胞 , 特级胎牛血清
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Excessive consumption of mucin by over-colonized Akkermansia muciniphila promotes intestinal barrier damage during malignant intestinal environment (2023-03-02)
作者：Shuang Qu:1.College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, China. ; Yinghui Zheng:1.College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, China. ; Yichun Huang:1.College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, China. ; Yicheng Feng:1.College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, China. ; Kunyao Xu:1.College of Life Science and Technology, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, China. ; Wei Zhang:1.College of Life Science and
期刊：Excessive consumption of mucin by over-colonized Akkermansia muciniphila promotes intestinal barrier damage during malignant intestinal environment
DOI：10.3389/fmicb.2023.1111911
影响因子 ：5.2
引用产品： CT26.WT 细胞
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Ferulic Acid Induces Autophagy and Apoptosis in Colon Cancer CT26 Cells via the MAPK Pathway (2023-08-11)
作者：Shanbin Chen:1.China National Research Institute of Food and Fermentation Industries, Beijing 100015, China. ; 2.International Joint Research Center of Quality and Safety of Alcoholic Beverages, Beijing,100015, China. ; Dong Zhao:1.Yibin Wuliangye Co., Ltd., Yibin 644000, China. ; Chunguang Luan:1.China National Research Institute of Food and Fermentation Industries, Beijing 100015, China. ; 2.International Joint Research Center of Quality and Safety of Alcoholic Beverages, Beijing,100015, China. ; Jia Zheng:1.Yibin Wuliangye Co., Ltd., Yibin 644000, China. ; Wei Liu:1.China National Research Institute of Food and Fermentation Industries, Beijing 100015, China. ; 2.International Joint Research Center of Quality and Safety of Alcoholic Beverages, Beijing,100015, China. ; Zheng Feng:1.Yibin Wuliangye Co., Ltd., Yibin 644000, China. ; Ruiqi Luo:1.China National Research Institute of Food and Fermentation Industries, Beijing 100015, China. ; 2.International Joint Research Center of Q
期刊：Ferulic Acid Induces Autophagy and Apoptosis in Colon Cancer CT26 Cells via the MAPK Pathway
影响因子 ：4.6
引用产品： CT26.WT 细胞
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Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway (2023-12-27)
作者：Fenglin Luo:1.Department of Pharmacology, School of Pharmacy, Chengdu Medical College, Chengdu 610500, China. ; 2.Department of Pharmacy, Study on the Structure-Specific Small Molecule Drug in Sichuan Province College Key Laboratory, Chengdu Medical College, Chengdu 610500, China. ; Yimeng Tang:1.Department of Pharmacology, School of Pharmacy, Chengdu Medical College, Chengdu 610500, China. ; 2.Department of Pharmacy, Study on the Structure-Specific Small Molecule Drug in Sichuan Province College Key Laboratory, Chengdu Medical College, Chengdu 610500, China. ; Lin Zheng:1.Department of Pharmacology, School of Pharmacy, Chengdu Medical College, Chengdu 610500, China. ; 2.Department of Pharmacy, Study on the Structure-Specific Small Molecule Drug in Sichuan Province College Key Laboratory, Chengdu Medical College, Chengdu 610500, China. ; Ying Yang:1.Department of Pharmacology, School of Pharmacy, Chengdu Medical College, Chengdu 610500, China. ; 2.Department of Pharmacy, Study on th
期刊：Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway
影响因子 ：4.6
引用产品： HCT 116 细胞 , SW480 [SW-480] 细胞 , CT26.WT 细胞
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Self-Assembled Amphiphilic Camptothecin Nanoparticles with Glutathione-Responsive and Tumor-Targeting Ability for Enhanced Colorectal Cancer Therapy (2023-09-21)
作者：XiaoJie Song: 1.Department of Bioengineering, School of Life Sciences, Zhengzhou University, 100 # Science Avenue, Zhengzhou, 450001 P. R. China;2.Collaborative Innovation Center of New Drug Research and Safety Evaluation of Henan Province, Zhengzhou, 450001 China;3.E-mail: songxj@zzu.edu.cn; Kang-Li Lan: 1.Department of Bioengineering, School of Life Sciences, Zhengzhou University, 100 # Science Avenue, Zhengzhou, 450001 P. R. China; Yi-Fei Xue: 1.Department of Bioengineering, School of Life Sciences, Zhengzhou University, 100 # Science Avenue, Zhengzhou, 450001 P. R. China; Hong-Min Liu: 1.Collaborative Innovation Center of New Drug Research and Safety Evaluation of Henan Province, Zhengzhou, 450001 China; Qi-Yan Lv: 1.Department of Bioengineering, School of Life Sciences, Zhengzhou University, 100 # Science Avenue, Zhengzhou, 450001 P. R. China; Zhen Zhao: 1.Key Laboratory of Cardio-cerebrovascular Drug, Topfond Pharmaceutical Co., Ltd, Guangming Road, Zhumadian, Henan Province, Chi
期刊：Self-Assembled Amphiphilic Camptothecin Nanoparticles with Glutathione-Responsive and Tumor-Targeting Ability for Enhanced Colorectal Cancer Therapy
影响因子 ：4.6
引用产品： CT26.WT 细胞
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Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression (2023-03-22)
作者：Yu Sun:1.Guangdong Provincial Key Laboratory of Digestive Cancer Research; Digestive Diseases Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China; Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China. ; Wenjun Xiao:1.Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China. ; Yang Yu:1.Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China. ; Yuchen Jiang:1.Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China. ; Zhijie Xiao:1.Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China. ; Defa Huang:1.Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi Province, 341004, China. ; Tianyu Zhong:1.Department of Laboratory Medicine,
期刊：Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression
DOI：10.1016/j.yexcr.2023.113565
影响因子 ：3.7
引用产品： CT26.WT 细胞
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MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mTOR signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer (2023-11-30)
作者：Chao Wang:1.Department of General Surgery, the First Affiliated Hospital of Dalian Medical University, Dalian, China. wang15940192769@163.com. ; Haonan Lin:1.Department of General Surgery, the First Affiliated Hospital of Dalian Medical University, Dalian, China. sxlhnsx@163.com. ; Wangqiang Zhao:1.Department of General Surgery, the First Affiliated Hospital of Dalian Medical University, Dalian, China. zwq1782194564@outlook.com. ; Yixuan Liang:1.Department of General Surgery, the First Affiliated Hospital of Dalian Medical University, Dalian, China. 18132052191@163.com. ; Yao Chen:1.Department of General Surgery, the First Affiliated Hospital of Dalian Medical University, Dalian, China. clieachen1992@163.com. ; Changmiao Wang:1.Department of General Surgery, the First Affiliated Hospital of Dalian Medical University, Dalian, China. wcmdyyy@163.com. ;
期刊：MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mTOR signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer
DOI：10.14715/cmb/2023.69.12.37
影响因子 ：1.6
引用产品： CT26.WT 细胞
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Nitroreductase-instructed supramolecular assemblies for microbiome regulation to enhance colorectal cancer treatments (2022-11-09)
作者：Jiali Chen:1.CAS Center for Excellence in Nanoscience, CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China. ; 2.University of Chinese Academy of Sciences, Beijing 100049, China. ; Pai Zhang:1.CAS Center for Excellence in Nanoscience, CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China. ; 2.Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid Wastes, National Laboratory of Mineral Materials, School of Materials Science and Technology, China University of Geosciences, Beijing 100083, China. ; Yan Zhao:1.CAS Center for Excellence in Nanoscience, CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China. ; 2.University of Chinese Academy of Sciences, Beijing 100049, China. ; Jie Zhao:1.CAS Cen
期刊：Nitroreductase-instructed supramolecular assemblies for microbiome regulation to enhance colorectal cancer treatments
影响因子 ：15.0
引用产品： Hela 细胞 , HT-29 细胞 , HCT 116 细胞 , CT26.WT 细胞 , DMEM高糖 培养基 , McCoy's 5A 培养基 , RPMI-1640 培养基
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A hybrid of lactic acid bacteria and metal-organic frameworks potentiates photodynamic immunotherapy for hypoxia-targeted tumor eradication (2022-08-12)
作者：Tianzhong Li (**田忠): 1.Interdisciplinary Center of High Magnetic Field Physics of Shenzhen University, College of Physics and Optoelectronic Engineering, Department of Otolaryngology, Shenzhen Institute of Translational Medicine, Shenzhen Second People’s Hospital, the First Affiliated Hospital, Shenzhen University, Shenzhen, 518060, China;2.Shenzhen International Institute for Biomedical Research, Shenzhen, 518000, China; Han Zhang (张晗): 1.Interdisciplinary Center of High Magnetic Field Physics of Shenzhen University, College of Physics and Optoelectronic Engineering, Department of Otolaryngology, Shenzhen Institute of Translational Medicine, Shenzhen Second People’s Hospital, the First Affiliated Hospital, Shenzhen University, Shenzhen, 518060, China; **yong Wang (王金勇): 1.Shenzhen International Institute for Biomedical Research, Shenzhen, 518000, China; Jiangtian Yu (于江天): 1.Shenzhen International Institute for Biomedical Research, S
期刊：A hybrid of lactic acid bacteria and metal-organic frameworks potentiates photodynamic immunotherapy for hypoxia-targeted tumor eradication
影响因子 ：8.6
引用产品： CT26.WT 细胞 , RAW 264.7 细胞
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CAR-T-Cell Therapy for Solid Tumors Positive for Fibronectin Extra Domain B (2022-09-14)
作者：Zhijie Zhang:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Chang Liu:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Zhe Yang:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ; Hongping Yin:1.School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China. ;
期刊：CAR-T-Cell Therapy for Solid Tumors Positive for Fibronectin Extra Domain B
影响因子 ：7.7
引用产品： U-87 MG 细胞 , A549 [A-549] 细胞 , F9 细胞 , CT26.WT 细胞
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Arrangement of Indocyanine Green in a 1.5-Nanometer Channel to Achieve High-Efficiency Imaging of the Intestinal Lymphatic System (2022-12-08)
作者：Xiangyi Kong:1.Key Laboratory of Lymphatic Surgery Jilin Province, Jilin Engineering Laboratory for Lymphatic Surgery Jilin Province, China-Japan Union Hospital of Jilin University, Changchun 130031, China. ; Nan Gao:1.Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education, Faculty of Chemistry, Northeast Normal University, Changchun 130024, China. ; Jianshi Du:1.Key Laboratory of Lymphatic Surgery Jilin Province, Jilin Engineering Laboratory for Lymphatic Surgery Jilin Province, China-Japan Union Hospital of Jilin University, Changchun 130031, China. ; Qing Zhao:1.Key Laboratory of Lymphatic Surgery Jilin Province, Jilin Engineering Laboratory for Lymphatic Surgery Jilin Province, China-Japan Union Hospital of Jilin University, Changchun 130031, China. ;
期刊：Arrangement of Indocyanine Green in a 1.5-Nanometer Channel to Achieve High-Efficiency Imaging of the Intestinal Lymphatic System
影响因子 ：4.9
引用产品： 小鼠淋巴管内皮细胞 , RAW 264.7 细胞 , CT26.WT 细胞
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A serum metabolomics study based on LC-MS: Chemosensitization effects of Rauvolfia vomitoria Afzel. combined with 5- fluorouracil on colorectal cancer mice (2022-09-22)
作者：Zhi-Fan Wang:1.School of Pharmacy Sciences, Shandong University, 44# West Wenhua Road, Jinan 250012, China. ; Wen-Ru Kong:1.School of Pharmacy Sciences, Shandong University, 44# West Wenhua Road, Jinan 250012, China. ; Ning Wang:1.School of Pharmacy Sciences, Shandong University, 44# West Wenhua Road, Jinan 250012, China. ; Yu-Lin You:1.School of Pharmacy Sciences, Shandong University, 44# West Wenhua Road, Jinan 250012, China. ; Jian-Feng Wang:1.Department of Pain Management, Qilu Hospital of Shandong University, 107# West Wenhua Road, Jinan 250012, China. Electronic address: wangjianfeng123456@126.com. ; Shu-Qi Wang:1.School of Pharmacy Sciences, Shandong University, 44# West Wenhua Road, Jinan 250012, China. Electronic address: wangsq@sdu.edu.cn. ;
期刊：A serum metabolomics study based on LC-MS: Chemosensitization effects of Rauvolfia vomitoria Afzel. combined with 5- fluorouracil on colorectal cancer mice
DOI：10.1016/j.jpba.2022.115074
影响因子 ：3.6
引用产品： CT26.WT 细胞
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Disulfiram-loaded hollow copper sulfide nanoparticles show anti-tumor effects in preclinical models of colorectal cancer (2022-10-07)
作者：Zeyidan Jiapaer:1.College of Life Science & Technology, Xinjiang University, Xinjiang, 830046, China; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, Xinjiang, 830046, China. Electronic address: zeyidan@xju.edu.cn. ; Lingying Zhang:1.College of Life Science & Technology, Xinjiang University, Xinjiang, 830046, China; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, Xinjiang, 830046, China. ; Wanli Ma:1.100049 State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China. ; Haoqiang Liu:1.College of Life Science & Technology, Xinjiang University, Xinjiang, 830046, China; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, Xinjiang, 830046, China. ; Chengyu Li:1.College of Life Science & Technology, Xinjiang University, Xinjiang, 830046, China; Xinjiang Key Laborator
期刊：Disulfiram-loaded hollow copper sulfide nanoparticles show anti-tumor effects in preclinical models of colorectal cancer
DOI：10.1016/j.bbrc.2022.10.027
影响因子 ：3.3
引用产品： CT26.WT 细胞
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Danggui Buxue Decoction in the Treatment of Metastatic Colon Cancer: Network Pharmacology Analysis and Experimental Validation (2002-01-20)
作者：Shi-Han Feng:1.Yong Chuan Hospital of Chongqing Medical University, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, People's Republic of China. ; Bin Zhao:1.Yong Chuan Hospital of Chongqing Medical University, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, People's Republic of China. ; Xue Zhan:1.College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, People's Republic of China. ; Retsepile Motanyane:1.College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, People's Republic of China. ; Shu-Mei Wang:1.College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metab
期刊：Danggui Buxue Decoction in the Treatment of Metastatic Colon Cancer: Network Pharmacology Analysis and Experimental Validation
影响因子 ：4.3
引用产品： CT26.WT 细胞
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Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer (2001-00-20)
作者：Man Hu:1.Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Zhaomin Yu:1.Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Peiyuan Mei:1.Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Jinxiao Li:1.Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Dan Luo:1.Department of Respiratory Medicine, Wuhan First Hospital, Wuhan, China. ; Haiming Zhang:1.Department of Oncology, Integrated Traditional Chinese and Western Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Minfe
期刊：Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer
影响因子 ：5.2
引用产品： HCT 116 细胞 , SW480 [SW-480] 细胞 , RKO 细胞 , CT26.WT 细胞
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Gut Microbiome Influences the Efficacy of PD-1 Antibody Immunotherapy on MSS-Type Colorectal Cancer via Metabolic Pathway (2004-00-20)
作者：Xinjian Xu:1.Second Department of Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China. ; Ji Lv:1.Second Department of Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China. ; 2.Department of Surgery, First Hospital of Qinhuangdao, Qinhuangdao, China. ; Fang Guo:1.Department of Pharmacology, Hebei Medical University, Shijiazhuang, China. ; Jing Li:1.Department of Traditional Chinese Medicine, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China. ; 2.College of Combine Traditional Chinese and Western Medicine, Hebei Medical University, Shijiazhuang, China. ; Yitao Jia:1.Third Department of Oncology, Hebei General Hospital, Shijiazhuang, China. ; Da Jiang:1.Department of Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China. ; Na Wang:1.Department of Pharmacology, Hebei Medical University, Shijiazhuang, China. ; Chao Zhang:1.Department of Clinical Laboratory, The Fourth Hospital of Hebei Medi
期刊：Gut Microbiome Influences the Efficacy of PD-1 Antibody Immunotherapy on MSS-Type Colorectal Cancer via Metabolic Pathway
影响因子 ：5.2
引用产品： CT26.WT 细胞
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Bifunctional liposomes reduce the chemotherapy resistance of doxorubicin induced by reactive oxygen species (2008-09-20)
作者：Lei Xu:1.College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China. zhuyish@njtech.edu.cn and State Key Laboratory of Pharmaceutical Biotechnology, Medical School and School of life science, Nanjing University, Nanjing 210093, China. huyiqiao@nju.edu.cn. ; Zhicheng Zhang:1.State Key Laboratory of Pharmaceutical Biotechnology, Medical School and School of life science, Nanjing University, Nanjing 210093, China. huyiqiao@nju.edu.cn. ; Yawen Ding:1.State Key Laboratory of Pharmaceutical Biotechnology, Medical School and School of life science, Nanjing University, Nanjing 210093, China. huyiqiao@nju.edu.cn. ; Li Wang:1.State Key Laboratory of Pharmaceutical Biotechnology, Medical School and School of life science, Nanjing University, Nanjing 210093, China. huyiqiao@nju.edu.cn. ; Yali Cheng:1.State Key Laboratory of Pharmaceutical Biotechnology, Medical School and School of life science, Nanjing University, Nanjing 210093, China. huyiqiao@nj
期刊：Bifunctional liposomes reduce the chemotherapy resistance of doxorubicin induced by reactive oxygen species
影响因子 ：6.6
引用产品： CT26.WT 细胞
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A tungsten nitride-based degradable nanoplatform for dual-modal image-guided combinatorial chemo-photothermal therapy of tumors (2012-08-20)
作者：Cheng Zhang:1.Key Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan 430072, P. R. China. zlzhong@whu.edu.cn xz-zhang@whu.edu.cn. ; Shi-Bo Wang: Zhao-Xia Chen: Jin-Xuan Fan: Zhen-Lin Zhong: Xian-Zheng Zhang:
期刊：A tungsten nitride-based degradable nanoplatform for dual-modal image-guided combinatorial chemo-photothermal therapy of tumors
影响因子 ：6.7
引用产品： CT26.WT 细胞 , 4T1 细胞
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